7MXI
| IgE-Fc in complex with DARPins E2_79 and E3_53 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-IgE Inhibitor E2_79, DARPin E3_53, ... | 著者 | Pennington, L.F, Jardetzky, T.J. | 登録日 | 2021-05-19 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure-guided design of ultrapotent disruptive IgE inhibitors to rapidly terminate acute allergic reactions. J.Allergy Clin.Immunol., 148, 2021
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7SHY
| IgE-Fc in complex with omalizumab scFv | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, IgE Fc, ... | 著者 | Pennington, L.F, Jardetzky, T.J, Kleinboelting, S. | 登録日 | 2021-10-11 | 公開日 | 2021-12-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex. Nat Commun, 12, 2021
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7SI0
| IgE-Fc in complex with 813 | 分子名称: | 813 Variable fragment Heavy chain, 813 Variable fragment Light chain, IgE Fc, ... | 著者 | Pennington, L.F, Jardetzky, T.J, Kleinboelting, S. | 登録日 | 2021-10-12 | 公開日 | 2021-12-15 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex. Nat Commun, 12, 2021
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7SHZ
| IgE-Fc in complex with HAE | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ... | 著者 | Pennington, L.F, Jardetzky, T.J, Kleinboelting, S. | 登録日 | 2021-10-11 | 公開日 | 2021-12-22 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex. Nat Commun, 12, 2021
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7SHU
| IgE-Fc in complex with omalizumab variant C02 | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Immunoglobulin heavy constant epsilon, ... | 著者 | Pennington, L.F, Jardetzky, T.J, Kleinboelting, S. | 登録日 | 2021-10-11 | 公開日 | 2021-12-15 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Directed evolution of and structural insights into antibody-mediated disruption of a stable receptor-ligand complex. Nat Commun, 12, 2021
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