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PDB: 6 件
2G7I
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BU of 2g7i by Molmil
Structure of Human Complement Factor H Carboxyl Terminal Domains 19-20: a Basis for Atypical Hemolytic Uremic Syndrome
分子名称: Complement factor H
著者Jaakola, V.-P, Jokiranta, T.S, Goldman, A.
登録日2006-02-28
公開日2006-05-23
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure of complement factor H carboxyl-terminus reveals molecular basis of atypical haemolytic uremic syndrome.
Embo J., 25, 2006
3EML
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BU of 3eml by Molmil
The 2.6 A Crystal Structure of a Human A2A Adenosine Receptor bound to ZM241385.
分子名称: 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, Human Adenosine A2A receptor/T4 lysozyme chimera, STEARIC ACID, ...
著者Jaakola, V.-P, Griffith, M.T, Hanson, M.A, Cherezov, V, Chien, E.Y.T, Lane, J.R, Ijzerman, A.P, Stevens, R.C, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR)
登録日2008-09-24
公開日2008-10-14
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist.
Science, 322, 2008
8QJ2
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BU of 8qj2 by Molmil
Structure of active state MC4R in complex with a potent ligand mimicking nanobody
分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ...
著者Busch, A, Jaakola, V.-P, Masiulis, S.
登録日2023-09-12
公開日2024-09-25
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure of active state MC4R in complex with a potent ligand mimicking nanobody
To Be Published
6RNK
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BU of 6rnk by Molmil
Crystal structure of a humanized (K18E, K269N) rat succinate receptor SUCNR1 (GPR91) in complex with a nanobody and antagonist NF-56-EJ40.
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 2-[2-[[3-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]phenyl]carbonylamino]phenyl]ethanoic acid, GLYCEROL, ...
著者Haffke, M, Jaakola, V.-P.
登録日2019-05-08
公開日2019-08-14
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structural basis of species-selective antagonist binding to the succinate receptor.
Nature, 574, 2019
6IBB
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BU of 6ibb by Molmil
Crystal structure of the rat isoform of the succinate receptor SUCNR1 (GPR91) in complex with a nanobody
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2~{S},5~{R})-hexane-2,5-diol, CHOLESTEROL, ...
著者Haffke, M, Jaakola, V.-P.
登録日2018-11-29
公開日2019-08-14
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献Structural basis of species-selective antagonist binding to the succinate receptor.
Nature, 574, 2019
3D4S
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BU of 3d4s by Molmil
Cholesterol bound form of human beta2 adrenergic receptor.
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol, Beta-2 adrenergic receptor/T4-lysozyme chimera, ...
著者Hanson, M.A, Cherezov, V, Roth, C.B, Griffith, M.T, Jaakola, V.-P, Chien, E.Y.T, Velasquez, J, Kuhn, P, Stevens, R.C, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D), GPCR Network (GPCR)
登録日2008-05-14
公開日2008-06-17
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A specific cholesterol binding site is established by the 2.8 A structure of the human beta2-adrenergic receptor.
Structure, 16, 2008

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件を2024-11-06に公開中

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