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PDB: 108 件
8Q44
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Crystal structure of cA4-bound Can2 (E364R) in complex with oligo-T DNA
分子名称: Cyclic tetraadenosine monophosphate (cA4), DNA (5'-D(*TP*TP*T)-3'), DUF1887 family protein, ...
著者Jungfer, K, Sigg, A, Jinek, M.
登録日2023-08-04
公開日2023-11-22
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Substrate selectivity and catalytic activation of the type III CRISPR ancillary nuclease Can2.
Nucleic Acids Res., 52, 2024
7QR5
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SpCas9 bound to FANCF off-target6 DNA substrate
分子名称: 1,2-ETHANEDIOL, CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target6 non-target strand, ...
著者Pacesa, M, Jinek, M.
登録日2022-01-17
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQO
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SpCas9 bound to AAVS1 off-target1 DNA substrate
分子名称: AAVS1 off-target1 non-target strand, AAVS1 off-target1 target strand, AAVS1 sgRNA, ...
著者Pacesa, M, Jinek, M.
登録日2022-01-10
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQP
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SpCas9 bound to AAVS1 off-target3 DNA substrate
分子名称: 1,2-ETHANEDIOL, AAVS1 off-target3 non-target strand, AAVS1 off-target3 target strand, ...
著者Pacesa, M, JInek, M.
登録日2022-01-10
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQS
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BU of 7qqs by Molmil
SpCas9 bound to FANCF on-target DNA substrate
分子名称: CRISPR-associated endonuclease Cas9/Csn1, FANCF on-target non-target strand, FANCF on-target target strand, ...
著者Pacesa, M, Jinek, M.
登録日2022-01-10
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQQ
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SpCas9 bound to AAVS1 off-target4 DNA substrate
分子名称: 1,2-ETHANEDIOL, AAVS1 off-target4 non-target strand, AAVS1 off-target4 target strand, ...
著者Pacesa, M, Jinek, M.
登録日2022-01-10
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQU
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BU of 7qqu by Molmil
SpCas9 bound to FANCF off-target2 DNA substrate
分子名称: CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target2 non-target strand, FANCF off-target2 target strand, ...
著者Pacesa, M, Jinek, M.
登録日2022-01-10
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQT
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SpCas9 bound to FANCF off-target1 DNA substrate
分子名称: CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target1 non-target strand, FANCF off-target1 target strand, ...
著者Pacesa, M, Jinek, M.
登録日2022-01-10
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QR8
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SpCas9 bound to PTPRC off-target1 DNA substrate
分子名称: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, POTASSIUM ION, ...
著者Pacesa, M, Jinek, M.
登録日2022-01-10
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQX
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SpCas9 bound to FANCF off-target5 DNA substrate
分子名称: CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target5 non-target strand, FANCF off-target5 target strand, ...
著者Pacesa, M, Jinek, M.
登録日2022-01-10
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QR0
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BU of 7qr0 by Molmil
SpCas9 bound to TRAC off-target1 DNA substrate
分子名称: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, POTASSIUM ION, ...
著者Pacesa, M, Jinek, M.
登録日2022-01-10
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQZ
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BU of 7qqz by Molmil
SpCas9 bound to FANCF off-target7 DNA substrate
分子名称: CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target7 non-target strand, FANCF off-target7 target strand, ...
著者Pacesa, M, Jinek, M.
登録日2022-01-10
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QQW
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BU of 7qqw by Molmil
SpCas9 bound to FANCF off-target4 DNA substrate
分子名称: CRISPR-associated endonuclease Cas9/Csn1, FANCF off-target4 non-target strand, FANCF off-target4 target strand, ...
著者Pacesa, M, Jinek, M.
登録日2022-01-10
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QR1
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BU of 7qr1 by Molmil
SpCas9 bound to TRAC off-target2 DNA substrate
分子名称: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, POTASSIUM ION, ...
著者Pacesa, M, Jinek, M.
登録日2022-01-10
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
7QR7
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BU of 7qr7 by Molmil
SpCas9 bound to AAVS1 off-target2 DNA substrate
分子名称: AAVS1 off-target2 non-target strand, AAVS1 off-target2 target strand, AAVS1 sgRNA, ...
著者Pacesa, M, JInek, M.
登録日2022-01-10
公開日2022-10-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for Cas9 off-target activity.
Cell, 185, 2022
8R3Z
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BU of 8r3z by Molmil
Cryo-EM structure of the Asgard archaeal Argonaute HrAgo1 bound to a guide RNA
分子名称: HrAgo1, MAGNESIUM ION, RNA (5'-R(P*UP*GP*AP*GP*GP*U*(MG))-3')
著者Finocchio, G, Swarts, D, Jinek, M.
登録日2023-11-10
公開日2024-06-19
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献RNA-guided RNA silencing by an Asgard archaeal Argonaute.
Nat Commun, 15, 2024
6F9W
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BU of 6f9w by Molmil
Crystal structure of the LSM domain of LSM14 in complex with a C-terminal peptide of 4E-T
分子名称: Eukaryotic translation initiation factor 4E transporter, Protein LSM14 homolog A
著者Brandmann, T, Jinek, M.
登録日2017-12-15
公開日2018-03-21
最終更新日2018-04-11
実験手法X-RAY DIFFRACTION (2.623 Å)
主引用文献Molecular architecture of LSM14 interactions involved in the assembly of mRNA silencing complexes.
EMBO J., 37, 2018
3P3I
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BU of 3p3i by Molmil
Crystal structure of the F36A mutant of the fluoroacetyl-CoA-specific thioesterase FlK in complex with fluoroacetate and CoA
分子名称: COENZYME A, Fluoroacetyl coenzyme A thioesterase, fluoroacetic acid
著者Weeks, A.M, Coyle, S.M, Jinek, M, Doudna, J.A, Chang, M.C.Y.
登録日2010-10-04
公開日2010-10-20
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity.
Biochemistry, 49, 2010
3P2S
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BU of 3p2s by Molmil
Crystal structure of the fluoroacetyl-CoA-specific thioesterase FlK in an open conformation
分子名称: Fluoroacetyl coenzyme A thioesterase
著者Weeks, A.M, Coyle, S.M, Jinek, M, Doudna, J.A, Chang, M.C.Y.
登録日2010-10-04
公開日2010-10-20
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity.
Biochemistry, 49, 2010
3P2R
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Crystal structure of the fluoroacetyl-CoA-specific thioesterase FlK in complex with fluoroacetate
分子名称: Fluoroacetyl coenzyme A thioesterase, fluoroacetic acid
著者Weeks, A.M, Coyle, S.M, Jinek, M, Doudna, J.A, Chang, M.C.Y.
登録日2010-10-03
公開日2010-10-20
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity.
Biochemistry, 49, 2010
3P3F
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BU of 3p3f by Molmil
Crystal structure of the F36A mutant of the fluoroacetyl-CoA-specific thioesterase FlK
分子名称: Fluoroacetyl coenzyme A thioesterase
著者Weeks, A.M, Coyle, S.M, Jinek, M, Doudna, J.A, Chang, M.C.Y.
登録日2010-10-04
公開日2010-10-20
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity.
Biochemistry, 49, 2010
3P2Q
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Crystal structure of the fluoroacetyl-CoA-specific thioesterase, FlK
分子名称: Fluoroacetyl coenzyme A thioesterase
著者Weeks, A.M, Coyle, S.M, Jinek, M, Doudna, J.A, Chang, M.C.Y.
登録日2010-10-03
公開日2010-10-20
最終更新日2011-11-16
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity.
Biochemistry, 49, 2010
6I0T
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Crystal structure of DmTailor in complex with GpU
分子名称: RNA (5'-R(*GP*U)-3'), Terminal uridylyltransferase Tailor
著者Kroupova, A, Ivascu, A, Jinek, M.
登録日2018-10-26
公開日2018-12-05
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for acceptor RNA substrate selectivity of the 3' terminal uridylyl transferase Tailor.
Nucleic Acids Res., 47, 2019
6I0U
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Crystal structure of DmTailor in complex with U6 RNA
分子名称: MAGNESIUM ION, RNA (5'-R(*UP*UP*UP*U)-3'), Terminal uridylyltransferase Tailor
著者Kroupova, A, Ivascu, A, Jinek, M.
登録日2018-10-26
公開日2018-12-05
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.001 Å)
主引用文献Structural basis for acceptor RNA substrate selectivity of the 3' terminal uridylyl transferase Tailor.
Nucleic Acids Res., 47, 2019
6I0V
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Crystal structure of DmTailor in complex with CACAGU RNA
分子名称: MAGNESIUM ION, RNA (5'-R(*CP*AP*CP*AP*GP*U)-3'), Terminal uridylyltransferase Tailor
著者Kroupova, A, Ivascu, A, Jinek, M.
登録日2018-10-26
公開日2018-12-05
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.851 Å)
主引用文献Structural basis for acceptor RNA substrate selectivity of the 3' terminal uridylyl transferase Tailor.
Nucleic Acids Res., 47, 2019

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件を2024-09-11に公開中

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