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PDB: 5628 件

6Z8E
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Human Picobirnavirus Ht-CP VLP
分子名称: Capsid protein precursor
著者Ortega-Esteban, A, Mata, C.P, Rodriguez-Espinosa, M.J, Luque, D, Irigoyen, N, Rodriguez, J.M, de Pablo, P.J, Caston, J.R.
登録日2020-06-02
公開日2020-09-23
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Cryo-electron Microscopy Structure, Assembly, and Mechanics Show Morphogenesis and Evolution of Human Picobirnavirus.
J.Virol., 94, 2020
8TXR
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E. coli ExoVII(H238A)
分子名称: Exodeoxyribonuclease 7 large subunit, Exodeoxyribonuclease 7 small subunit
著者Liu, C, Berger, J.M.
登録日2023-08-24
公開日2024-01-31
最終更新日2024-02-07
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure of Escherichia coli exonuclease VII.
Proc.Natl.Acad.Sci.USA, 121, 2024
8U7M
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Human retinal variant phosphomimetic IMPDH1(595)-S477D free octamer bound by GTP, ATP, IMP, and NAD+
分子名称: ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ...
著者Calise, S.J, Kollman, J.M.
登録日2023-09-15
公開日2024-01-31
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Light-sensitive phosphorylation regulates retinal IMPDH1 activity and filament assembly.
J.Cell Biol., 223, 2024
5D7Z
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Crystal structure of glyoxalase I from Zea mays
分子名称: FORMIC ACID, Lactoylglutathione lyase, NICKEL (II) ION, ...
著者Gonzalez, J.M.
登録日2015-08-14
公開日2015-09-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Structure of the novel monomeric glyoxalase I from Zea mays.
Acta Crystallogr.,Sect.D, 71, 2015
6QM2
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NlaIV restriction endonuclease
分子名称: POTASSIUM ION, SODIUM ION, Type-2 restriction enzyme NlaIV
著者Czapinska, H, Siwek, W, Szczepanowski, R.H, Bujnicki, J.M, Bochtler, M, Skowronek, K.
登録日2019-02-01
公開日2019-05-01
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure and Directed Evolution of Specificity of NlaIV Restriction Endonuclease.
J.Mol.Biol., 431, 2019
5DBU
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Crystal structure of 2-deoxyribose-5-phosphate aldolase (1-220) from Streptococcus suis
分子名称: Deoxyribose-phosphate aldolase
著者Cao, T.-P, Choi, J.M, Lee, S.H.
登録日2015-08-22
公開日2016-04-13
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.797 Å)
主引用文献Structural insight for substrate tolerance to 2-deoxyribose-5-phosphate aldolase from the pathogen Streptococcus suis
J. Microbiol., 54, 2016
5D6W
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Crystal structure of double tudor domain of human lysine demethylase KDM4A
分子名称: Lysine-specific demethylase 4A, S,R MESO-TARTARIC ACID
著者Wang, F, Su, Z, Denu, J.M, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro)
登録日2015-08-13
公開日2015-11-25
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.992 Å)
主引用文献Reader domain specificity and lysine demethylase-4 family function.
Nat Commun, 7, 2016
8B8B
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Multimerization domain of Munia virus 1 phosphoprotein
分子名称: Munia Bornavirus 1 phosphoprotein, NITRATE ION
著者Chenavier, F, Tarbouriech, N, Bourhis, J.M, Tomonaga, K, Horie, M, Crepin, T.
登録日2022-10-04
公開日2022-11-23
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Borna Disease Virus 1 Phosphoprotein Forms a Tetramer and Interacts with Host Factors Involved in DNA Double-Strand Break Repair and mRNA Processing.
Viruses, 14, 2022
8B8A
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Multimerization domain of borna disease virus 1 phosphoprotein
分子名称: Phosphoprotein
著者Tarbouriech, N, Legrand, P, Bourhis, J.M, Chenavier, F, Freslon, L, Kawasaki, J, Horie, M, Tomonaga, K, Bachiri, K, Coyaud, E, Gonzalez-Dunia, D, Ruigrok, R.W.H, Crepin, T.
登録日2022-10-04
公開日2022-11-23
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Borna Disease Virus 1 Phosphoprotein Forms a Tetramer and Interacts with Host Factors Involved in DNA Double-Strand Break Repair and mRNA Processing.
Viruses, 14, 2022
6NSL
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CRYSTAL STRUCTURE OF TYROSINE KINASE 2 JH2 (PSEUDO KINASE DOMAIN) COMPLEXED WITH Compound-6c AKA 6-((1-(4-CYANOPHENY L)-2-OXO-1,2-DIHYDRO-3-PYRIDINYL)AMINO)-N-CYCLOPROPYL-8-(M ETHYLAMINO)IMIDAZO[1,2-B]PYRIDAZINE-3-CARBOXAMIDE
分子名称: 6-{[1-(4-cyanophenyl)-2-oxo-1,2-dihydropyridin-3-yl]amino}-N-cyclopropyl-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamide, Non-receptor tyrosine-protein kinase TYK2, SULFATE ION
著者Muckelbauer, J.M, Khan, J.A.
登録日2019-01-25
公開日2020-01-29
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Identification of Imidazo[1,2-b]pyridazine Derivatives as Potent, Selective, and Orally Active Tyk2 JH2 Inhibitors.
Acs Med.Chem.Lett., 10, 2019
5D5K
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Crystal Structure NLS from human PARP-2 complexed with Importin alpha delta IBB
分子名称: Importin subunit alpha-1, Poly [ADP-ribose] polymerase 2
著者Riccio, A.A, Cingolani, G, Pascal, J.M.
登録日2015-08-10
公開日2016-06-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献PARP-2 domain requirements for DNA damage-dependent activation and localization to sites of DNA damage.
Nucleic Acids Res., 44, 2016
5DHX
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HIV-1 Rev NTD dimers with variable crossing angles
分子名称: Anti-Rev Antibody Fab single-chain variable fragment, light chain,Anti-Rev Antibody Fab single-chain variable fragment, heavy chain, ...
著者DiMattia, M.A, Watts, N.R, Wingfield, P.T, Grimes, J.M, Stuart, D.I, Steven, A.C.
登録日2015-08-31
公開日2016-06-22
最終更新日2017-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The Structure of HIV-1 Rev Filaments Suggests a Bilateral Model for Rev-RRE Assembly.
Structure, 24, 2016
5DHY
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HIV-1 Rev NTD dimers with variable crossing angles
分子名称: Anti-Rev Antibody Fab single-chain variable fragment, heavy chain, light chain, ...
著者DiMattia, M.A, Watts, N.R, Wingfield, P.T, Grimes, J.M, Stuart, D.I, Steven, A.C.
登録日2015-08-31
公開日2016-06-22
最終更新日2017-08-30
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The Structure of HIV-1 Rev Filaments Suggests a Bilateral Model for Rev-RRE Assembly.
Structure, 24, 2016
6NO9
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PIM1 in complex with Cpd16 (5-amino-N-(5-((4R,5R)-4-amino-5-fluoroazepan-1-yl)-1-methyl-1H-pyrazol-4-yl)-2-(2,6-difluorophenyl)thiazole-4-carboxamide)
分子名称: 5-amino-N-{5-[(4R,5R)-4-amino-5-fluoroazepan-1-yl]-1-methyl-1H-pyrazol-4-yl}-2-(2,6-difluorophenyl)-1,3-thiazole-4-carboxamide, GLYCEROL, PHOSPHATE ION, ...
著者Murray, J.M, Noland, C.
登録日2019-01-15
公開日2019-02-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.712 Å)
主引用文献Optimization of Pan-Pim Kinase Activity and Oral Bioavailability Leading to Diaminopyrazole (GDC-0339) for the Treatment of Multiple Myeloma.
J. Med. Chem., 62, 2019
8VOL
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Apex domain deletion mutant of bacteriophage P2 central spike protein, membrane-piercing module
分子名称: PHOSPHATIDYLETHANOLAMINE, Spike protein
著者Leiman, P.G, Miller, J.M.
登録日2024-01-15
公開日2024-08-07
実験手法X-RAY DIFFRACTION (0.9 Å)
主引用文献Function of the bacteriophage P2 baseplate central spike Apex domain in the infection process.
bioRxiv, 2023
5DVX
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Crystal structure of the catalytic-domain of human carbonic anhydrase IX at 1.6 angstrom resolution
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Carbonic anhydrase 9, ...
著者Mahon, B.P, Socorro, L, Driscoll, J.M, McKenna, R.
登録日2015-09-21
公開日2016-08-03
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.598 Å)
主引用文献The Structure of Carbonic Anhydrase IX Is Adapted for Low-pH Catalysis.
Biochemistry, 55, 2016
8BEW
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Cryo-EM structure of the electron bifurcating Fe-Fe hydrogenase HydABC complex from Thermoanaerobacter kivui in the oxidised state
分子名称: Electron bifurcating hydrogenase subunit HydA1, Electron bifurcating hydrogenase subunit HydB, Electron bifurcating hydrogenase subunit HydC, ...
著者Kumar, A, Schuller, J.M.
登録日2022-10-22
公開日2023-02-15
最終更新日2023-03-29
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献Molecular Basis of the Electron Bifurcation Mechanism in the [FeFe]-Hydrogenase Complex HydABC.
J.Am.Chem.Soc., 145, 2023
8B8F
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Atomic structure of the beta-trefoil domain of the Laccaria bicolor lectin LBL in complex with lactose
分子名称: N-terminal beta-trefoil domain of the lectin LBL from Laccaria bicolor, beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose
著者Acebron, I, Campanero-Rhodes, M.A, Solis, D, Menendez, M, Garcia, C, Lillo, M.P, Mancheno, J.M.
登録日2022-10-04
公開日2023-02-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Atomic crystal structure and sugar specificity of a beta-trefoil lectin domain from the ectomycorrhizal basidiomycete Laccaria bicolor.
Int.J.Biol.Macromol., 233, 2023
8B4H
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IstA transposase cleaved donor complex
分子名称: DNA (55-MER) / right IS21 transposon end (insertion sequence IS5376), DNA (57-MER) / right IS21 transposon end (insertion sequence IS5376), MAGNESIUM ION, ...
著者Spinola-Amilibia, M, de la Gandara, A, Araujo-Bazan, L, Berger, J.M, Arias-Palomo, E.
登録日2022-09-20
公開日2023-05-03
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献IS21 family transposase cleaved donor complex traps two right-handed superhelical crossings.
Nat Commun, 14, 2023
8BVP
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Crystal structure of an N-terminal fragment of the effector protein Lpg2504 (SidI) from Legionella pneumophila
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Restriction endonuclease
著者Machtens, D.A, Willerding, J.M, Eschenburg, S, Reubold, T.F.
登録日2022-12-05
公開日2023-05-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the N-terminal domain of the effector protein SidI of Legionella pneumophila reveals a glucosyl transferase domain.
Biochem.Biophys.Res.Commun., 661, 2023
6XPI
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CutR flat hexamer, form 1
分子名称: Ethanolamine utilization protein EutS
著者Ochoa, J.M, Sawaya, M.R, Nguyen, V.N, Duilio, C, Yeates, T.O.
登録日2020-07-08
公開日2020-07-22
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Symmetry breaking and structural polymorphism in a bacterial microcompartment shell protein for choline utilization.
Protein Sci., 29, 2020
5DOE
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Crystal structure of the Human Cytomegalovirus UL53 (residues 72-292)
分子名称: Virion egress protein UL31 homolog, ZINC ION
著者Lye, M.F, El Omari, K, Filman, D.J, Hogle, J.M.
登録日2015-09-11
公開日2015-11-25
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Unexpected features and mechanism of heterodimer formation of a herpesvirus nuclear egress complex.
Embo J., 34, 2015
6XPJ
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CutR flat hexamer, form 2
分子名称: Ethanolamine utilization protein EutS, SULFATE ION
著者Ochoa, J.M, Sawaya, M.R, Nguyen, V.N, Duilio, C, Yeates, T.O.
登録日2020-07-08
公開日2020-07-22
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Symmetry breaking and structural polymorphism in a bacterial microcompartment shell protein for choline utilization.
Protein Sci., 29, 2020
8BWY
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In situ outer dynein arm from Chlamydomonas reinhardtii in a pre-power stroke state
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Calmodulin, ...
著者Zimmermann, N.E.L, Noga, A, Obbineni, J.M, Ishikawa, T.
登録日2022-12-07
公開日2023-05-10
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (38 Å)
主引用文献ATP-induced conformational change of axonemal outer dynein arms revealed by cryo-electron tomography.
Embo J., 42, 2023
8BX8
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In situ outer dynein arm from Chlamydomonas reinhardtii in the post-power stroke state
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ...
著者Zimmermann, N.E.L, Noga, A, Obbineni, J.M, Ishikawa, T.
登録日2022-12-08
公開日2023-05-10
最終更新日2023-06-28
実験手法ELECTRON MICROSCOPY (30.299999 Å)
主引用文献ATP-induced conformational change of axonemal outer dynein arms revealed by cryo-electron tomography.
Embo J., 42, 2023

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