5MDE
 
 | | The structure of the mature HIV-1 CA hexameric lattice with curvature parameters: tilt=23, twist=0 | | 分子名称: | Capsid protein p24 C-terminal domain, Capsid protein p24 N-terminal domain | | 著者 | Mattei, S, Glass, B, Hagen, W.J.H, Kraeusslich, H.-G, Briggs, J.A.G. | | 登録日 | 2016-11-10 | | 公開日 | 2016-12-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (8.4 Å) | | 主引用文献 | The structure and flexibility of conical HIV-1 capsids determined within intact virions.
Science, 354, 2016
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4CF5
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6ZOY
 | | Structure of Disulphide-stabilized SARS-CoV-2 Spike Protein Trimer (x1 disulphide-bond mutant, S383C, D985C, K986P, V987P, single Arg S1/S2 cleavage site) in Closed State | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Xiong, X, Qu, K, Scheres, S.H.W, Briggs, J.A.G. | | 登録日 | 2020-07-08 | | 公開日 | 2020-07-22 | | 最終更新日 | 2021-06-02 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | A thermostable, closed SARS-CoV-2 spike protein trimer.
Nat.Struct.Mol.Biol., 27, 2020
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4CF3
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6ZPH
 | | Kinesin binding protein complexed with Kif15 motor domain | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, KIF-binding protein, Kinesin-like protein KIF15, ... | | 著者 | Atherton, J, Hummel, J.J.A, Olieric, N, Locke, J, Pena, A, Rosenfeld, S.S, Steinmetz, M.O, Hoogenraad, C.C, Moores, C.A. | | 登録日 | 2020-07-08 | | 公開日 | 2020-12-30 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (6.9 Å) | | 主引用文献 | The mechanism of kinesin inhibition by kinesin-binding protein.
Elife, 9, 2020
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4CDG
 | | Crystal structure of the Bloom's syndrome helicase BLM in complex with Nanobody | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BLOOM SYNDROME PROTEIN, NANOBODY, ... | | 著者 | Newman, J.A, Savitsky, P, Allerston, C.K, Pike, A.C.W, Pardon, E, Steyaert, J, Arrowsmith, C.H, von Delft, F, Bountra, C, Edwards, A, Gileadi, O. | | 登録日 | 2013-10-31 | | 公開日 | 2013-11-13 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.794 Å) | | 主引用文献 | Crystal Structure of the Bloom'S Syndrome Helicase Indicates a Role for the Hrdc Domain in Conformational Changes.
Nucleic Acids Res., 43, 2015
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4CE6
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5MDA
 | | The structure of the mature HIV-1 CA hexameric lattice with curvature parameters: tilt=17, twist=0 | | 分子名称: | Gag protein | | 著者 | Mattei, S, Glass, B, Hagen, W.J.H, Kraeusslich, H.-G, Briggs, J.A.G. | | 登録日 | 2016-11-10 | | 公開日 | 2016-12-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (8.4 Å) | | 主引用文献 | The structure and flexibility of conical HIV-1 capsids determined within intact virions.
Science, 354, 2016
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6ZP0
 | | Structure of SARS-CoV-2 Spike Protein Trimer (single Arg S1/S2 cleavage site) in Closed State | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Xiong, X, Qu, K, Scheres, S.H.W, Briggs, J.A.G. | | 登録日 | 2020-07-08 | | 公開日 | 2020-07-22 | | 最終更新日 | 2021-06-02 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | A thermostable, closed SARS-CoV-2 spike protein trimer.
Nat.Struct.Mol.Biol., 27, 2020
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1NOS
 | | MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN (DELTA 114), IMIDAZOLE COMPLEX | | 分子名称: | IMIDAZOLE, INDUCIBLE NITRIC OXIDE SYNTHASE, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Crane, B.R, Arvai, A.S, Getzoff, E.D, Stuehr, D.J, Tainer, J.A. | | 登録日 | 1997-09-28 | | 公開日 | 1998-10-14 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The structure of nitric oxide synthase oxygenase domain and inhibitor complexes.
Science, 278, 1997
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6ZPI
 | | Microtubule complexed with Kif15 motor domain. Symmetrised asymmetric unit | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF15, ... | | 著者 | Atherton, J, Hummel, J.J.A, Olieric, N, Locke, J, Pena, A, Rosenfeld, S.S, Steinmetz, M.O, Hoogenraad, C.C, Moores, C.A. | | 登録日 | 2020-07-08 | | 公開日 | 2020-12-30 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | The mechanism of kinesin inhibition by kinesin-binding protein.
Elife, 9, 2020
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4A4O
 | | CRYSTAL STRUCTURE OF POLO-LIKE KINASE 1 IN COMPLEX WITH A 2-(2-AMINO- PYRIMIDIN-4-YL)-1,5,6,7-TETRAHYDRO-PYRROLOPYRIDIN-4-ONE INHIBITOR | | 分子名称: | 1-METHYL-2-(2-{[5-(4-METHYLPIPERAZIN-1-YL)-2-(TRIFLUOROMETHOXY)PHENYL]AMINO}PYRIMIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE, L(+)-TARTARIC ACID, SERINE/THREONINE-PROTEIN KINASE PLK1, ... | | 著者 | Bertrand, J.A, Bossi, R.T. | | 登録日 | 2011-10-18 | | 公開日 | 2012-01-11 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | 5-(2-Amino-Pyrimidin-4-Yl)-1H-Pyrrole and 2-(2-Amino-Pyrimidin-4-Yl)-1,5,6,7-Tetrahydro-Pyrrolo[3,2-C]Pyridin-4-One Derivatives as New Classes of Selective and Orally Available Polo-Like Kinase 1 Inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
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1NOC
 | | MURINE INDUCIBLE NITRIC OXIDE SYNTHASE OXYGENASE DOMAIN (DELTA 114) COMPLEXED WITH TYPE I E. COLI CHLORAMPHENICOL ACETYL TRANSFERASE AND IMIDAZOLE | | 分子名称: | IMIDAZOLE, INDUCIBLE NITRIC OXIDE SYNTHASE, PROTOPORPHYRIN IX CONTAINING FE, ... | | 著者 | Crane, B.R, Arvai, A.S, Getzoff, E.D, Stuehr, D.J, Tainer, J.A. | | 登録日 | 1997-09-28 | | 公開日 | 1998-10-14 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The structure of nitric oxide synthase oxygenase domain and inhibitor complexes.
Science, 278, 1997
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463D
 | | CALCIUM FORM OF D(CGCGAATTCGCG)2 | | 分子名称: | CALCIUM ION, DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3') | | 著者 | Liu, J, Subirana, J.A. | | 登録日 | 1999-03-29 | | 公開日 | 1999-10-08 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Structure of d(CGCGAATTCGCG) in the presence of Ca(2+) ions.
J.Biol.Chem., 274, 1999
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473D
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4AJ1
 | | rat LDHA in complex with N-(2-(methylamino)-1,3-benzothiazol-6-yl) acetamide | | 分子名称: | GLYCEROL, L-LACTATE DEHYDROGENASE A CHAIN, MALONATE ION, ... | | 著者 | Tucker, J.A, Brassington, C, Hassall, G, Vogtherr, M, Ward, R, Tart, J, Davies, G. | | 登録日 | 2012-02-15 | | 公開日 | 2012-03-21 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | The Design and Synthesis of Novel Lactate Dehydrogenase a Inhibitors by Fragment-Based Lead Generation
J.Med.Chem., 55, 2012
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1ODS
 | | Cephalosporin C deacetylase from Bacillus subtilis | | 分子名称: | CEPHALOSPORIN C DEACETYLASE, CHLORIDE ION, MAGNESIUM ION | | 著者 | Vincent, F, Charnock, S.J, Verschueren, K.H.G, Turkenburg, J.P, Scott, D.J, Offen, W.A, Roberts, S, Pell, G, Gilbert, H.J, Brannigan, J.A, Davies, G.J. | | 登録日 | 2003-02-20 | | 公開日 | 2003-07-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Multifunctional Xylooligosaccharide/Cephalosporin C Deacetylase Revealed by the Hexameric Structure of the Bacillus Subtilis Enzyme at 1.9A Resolution
J.Mol.Biol., 330, 2003
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1O72
 | | Crystal structure of the water-soluble state of the pore-forming cytolysin Sticholysin II complexed with phosphorylcholine | | 分子名称: | PHOSPHOCHOLINE, STICHOLYSIN II | | 著者 | Mancheno, J.M, Martinez-Ripoll, M, Gavilanes, J.G, Hermoso, J.A. | | 登録日 | 2002-10-23 | | 公開日 | 2003-11-13 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Crystal and Electron Microscopy Structures of Sticholysin II Actinoporin Reveal Insights Into the Mechanism of Membrane Pore Formation
Structure, 11, 2003
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3OZM
 | | Crystal structure of enolase superfamily member from Bordetella bronchiseptica complexed with Mg, m-Xylarate and L-Lyxarate | | 分子名称: | D-xylaric acid, GLYCEROL, L-arabinaric acid, ... | | 著者 | Fedorov, A.A, Fedorov, E.V, Wichelecki, D, Gerlt, J.A, Almo, S.C. | | 登録日 | 2010-09-25 | | 公開日 | 2011-09-28 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of enolase superfamily member from Bordetella bronchiseptica complexed with Mg, m-Xylarate and L-Lyxarate
TO BE PUBLISHED
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426D
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1OGJ
 | | FERREDOXIN:NADP+ REDUCTASE MUTANT WITH LEU 263 REPLACED BY PRO (L263P) | | 分子名称: | FERREDOXIN--NADP+ REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION | | 著者 | Hermoso, J.A, Mayoral, T, Martinez Julvez, M, Medina, M, Sanz-Aparicio, J, Gomez-Moreno, C. | | 登録日 | 2003-05-06 | | 公開日 | 2003-09-25 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Involvement of the Pyrophosphate and the 2'-Phosphate Binding Regions of Ferredoxin-Nadp+ Reductase in Coenzyme Specificity
J.Biol.Chem., 278, 2003
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5MD4
 | | The structure of the mature HIV-1 CA hexameric lattice with curvature parameters: tilt=11, twist=6 | | 分子名称: | Capsid protein p24 | | 著者 | Mattei, S, Glass, B, Hagen, W.J.H, Kraeusslich, H.-G, Briggs, J.A.G. | | 登録日 | 2016-11-10 | | 公開日 | 2016-12-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (8.4 Å) | | 主引用文献 | The structure and flexibility of conical HIV-1 capsids determined within intact virions.
Science, 354, 2016
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5MDG
 | | The structure of the mature HIV-1 CA hexameric lattice with curvature parameters: tilt=29, twist=0 | | 分子名称: | Gag protein | | 著者 | Mattei, S, Glass, B, Hagen, W.J.H, Kraeusslich, H.-G, Briggs, J.A.G. | | 登録日 | 2016-11-10 | | 公開日 | 2016-12-28 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (8.7 Å) | | 主引用文献 | The structure and flexibility of conical HIV-1 capsids determined within intact virions.
Science, 354, 2016
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4A2I
 | | Cryo-electron Microscopy Structure of the 30S Subunit in Complex with the YjeQ Biogenesis Factor | | 分子名称: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | | 著者 | Jomaa, A, Stewart, G, Mears, J.A, Kireeva, I, Brown, E.D, Ortega, J. | | 登録日 | 2011-09-27 | | 公開日 | 2011-11-02 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (16.5 Å) | | 主引用文献 | Cryo-Electron Microscopy Structure of the 30S Subunit in Complex with the Yjeq Biogenesis Factor.
RNA, 17, 2011
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3P2R
 | | Crystal structure of the fluoroacetyl-CoA-specific thioesterase FlK in complex with fluoroacetate | | 分子名称: | Fluoroacetyl coenzyme A thioesterase, fluoroacetic acid | | 著者 | Weeks, A.M, Coyle, S.M, Jinek, M, Doudna, J.A, Chang, M.C.Y. | | 登録日 | 2010-10-03 | | 公開日 | 2010-10-20 | | 最終更新日 | 2011-11-16 | | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | | 主引用文献 | Structural and biochemical studies of a fluoroacetyl-CoA-specific thioesterase reveal a molecular basis for fluorine selectivity.
Biochemistry, 49, 2010
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