1V90
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![BU of 1v90 by Molmil](/molmil-images/mine/1v90) | Solution structure by NMR means of delta-paluIT1-NH2 | Descriptor: | Delta-palutoxin IT1 | Authors: | Ferrat, G, Bosmans, F, Tytgat, J, Pimentel, C, Chagot, B, Nakajima, T, Darbon, H, Corzo, G. | Deposit date: | 2004-01-19 | Release date: | 2005-03-29 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of two insect-specific spider toxins and their pharmacological interaction with the insect voltage-gated Na(+) channel Proteins, 59, 2005
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1UM6
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![BU of 1um6 by Molmil](/molmil-images/mine/1um6) | catalytic antibody 21h3 | Descriptor: | antibody 21h3, H chain, L chain | Authors: | Beuscher IV, A.E, Reuter, J, Olson, A.J, Romesberg, F.E, Schultz, P.G, Wirsching, P, Janda, K.D, Lerner, R.A, Stevens, R.C. | Deposit date: | 2003-09-23 | Release date: | 2004-10-05 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Studies of an Efficient Catalytic Antibody Operating by Ping-Pong and Induced Fit Mechanisms To be Published
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1UU4
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![BU of 1uu4 by Molmil](/molmil-images/mine/1uu4) | X-RAY CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMICOLA GRISEA CEL12A IN COMPLEX WITH CELLOBIOSE | Descriptor: | ENDO-BETA-1,4-GLUCANASE, TETRAETHYLENE GLYCOL, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | Authors: | Berglund, G.I, Shaw, A, Stahlberg, J, Kenne, L, Driguez, T.H, Mitchinson, C, Sandgren, M. | Deposit date: | 2003-12-15 | Release date: | 2004-09-16 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.49 Å) | Cite: | Crystal Complex Structures Reveal How Substrate is Bound in the -4 to the +2 Binding Sites of Humicola Grisea Cel12A J.Mol.Biol., 342, 2004
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1V91
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![BU of 1v91 by Molmil](/molmil-images/mine/1v91) | Solution structure of insectidal toxin delta-paluIT2-NH2 | Descriptor: | Delta-palutoxin IT2 | Authors: | Ferrat, G, Bosmans, F, Tytgat, J, Pimentel, C, Chagot, B, Nakajima, T, Darbon, H, Corzo, G. | Deposit date: | 2004-01-19 | Release date: | 2005-03-29 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | Solution structure of two insect-specific spider toxins and their pharmacological interaction with the insect voltage-gated Na(+) channel Proteins, 59, 2005
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1V1T
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![BU of 1v1t by Molmil](/molmil-images/mine/1v1t) | Crystal structure of the PDZ tandem of human syntenin in complex with TNEYKV peptide | Descriptor: | BENZOIC ACID, SYNTENIN 1, TNEYKV PEPTIDE | Authors: | Grembecka, J, Cierpicki, T, Devedjiev, Y, Cooper, D.R, Derewenda, U, Derewenda, Z.S. | Deposit date: | 2004-04-23 | Release date: | 2005-06-14 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The Binding of the Pdz Tandem of Syntenin to Target Proteins. Biochemistry, 45, 2006
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1V3N
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![BU of 1v3n by Molmil](/molmil-images/mine/1v3n) | Crystal structure of d(GCGAGAGC): the DNA quadruplex structure split from the octaplex | Descriptor: | 5'-D(*GP*(CBR)P*GP*AP*GP*AP*GP*C)-3', POTASSIUM ION | Authors: | Kondo, J, Umeda, S, Sunami, T, Takenaka, A. | Deposit date: | 2003-11-03 | Release date: | 2004-06-08 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structures of a DNA octaplex with I-motif of G-quartets and its splitting into two quadruplexes suggest a folding mechanism of eight tandem repeats Nucleic Acids Res., 32, 2004
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1V3P
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![BU of 1v3p by Molmil](/molmil-images/mine/1v3p) | Crystal structure of d(GCGAGAGC): the DNA octaplex structure with I-motif of G-quartet | Descriptor: | 5'-D(*GP*(C38)P*GP*AP*GP*AP*GP*C)-3', POTASSIUM ION | Authors: | Kondo, J, Umeda, S, Sunami, T, Takenaka, A. | Deposit date: | 2003-11-03 | Release date: | 2004-06-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structures of a DNA octaplex with I-motif of G-quartets and its splitting into two quadruplexes suggest a folding mechanism of eight tandem repeats Nucleic Acids Res., 32, 2004
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1V3W
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![BU of 1v3w by Molmil](/molmil-images/mine/1v3w) | Structure of Ferripyochelin binding protein from Pyrococcus horikoshii OT3 | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | Authors: | Jeyakanthan, J, Tahirov, T.H, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-11-07 | Release date: | 2003-11-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Observation of a calcium-binding site in the gamma-class carbonic anhydrase from Pyrococcus horikoshii. Acta Crystallogr.,Sect.D, 64, 2008
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1V8E
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![BU of 1v8e by Molmil](/molmil-images/mine/1v8e) | |
1UUH
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![BU of 1uuh by Molmil](/molmil-images/mine/1uuh) | Hyaluronan binding domain of human CD44 | Descriptor: | CD44 ANTIGEN | Authors: | Teriete, P, Banerji, S, Noble, M, Blundell, C, Wright, A, Pickford, A, Lowe, E, Mahoney, D, Tammi, M, Kahmann, J, Campbell, I, Day, A, Jackson, D. | Deposit date: | 2003-12-19 | Release date: | 2004-03-04 | Last modified: | 2019-05-29 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the Regulatory Hyaluronan-Binding Domain in the Inflammatory Leukocyte Homing Receptor Cd44 Mol.Cell, 13, 2004
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1UM5
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![BU of 1um5 by Molmil](/molmil-images/mine/1um5) | Catalytic Antibody 21H3 with alcohol substrate | Descriptor: | 1-PHENYLETHANOL, Antibody 21H3 H chain, Antibody 21H3 L chain | Authors: | Beuscher IV, A.E, Reuter, J, Olson, A.J, Romesberg, F.E, Schultz, P.G, Wirsching, P, Janda, K.D, Lerner, R.A, Stevens, R.C. | Deposit date: | 2003-09-23 | Release date: | 2004-10-05 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural Studies of an Efficient Catalytic Antibody Operating by Ping-Pong and Induced Fit Mechanisms To be Published
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1UTK
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![BU of 1utk by Molmil](/molmil-images/mine/1utk) | Trypsin specificity as elucidated by LIE calculations, X-ray structures and association constant measurements | Descriptor: | CALCIUM ION, SULFATE ION, TRYPSIN I | Authors: | Leiros, H.-K.S, Brandsdal, B.O, Andersen, O.A, Os, V, Leiros, I, Helland, R, Otlewski, J, Willassen, N.P, Smalas, A.O. | Deposit date: | 2003-12-09 | Release date: | 2004-01-29 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | Trypsin Specificity as Elucidated by Lie Calculations, X-Ray Structures, and Association Constant Measurements Protein Sci., 13, 2004
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1UTP
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![BU of 1utp by Molmil](/molmil-images/mine/1utp) | Trypsin specificity as elucidated by LIE calculations, X-ray structures and association constant measurements | Descriptor: | 4-PHENYLBUTYLAMINE, CALCIUM ION, GLYCEROL, ... | Authors: | Leiros, H.-K.S, Brandsdal, B.O, Andersen, O.A, Os, V, Leiros, I, Helland, R, Otlewski, J, Willassen, N.P, Smalas, A.O. | Deposit date: | 2003-12-09 | Release date: | 2004-01-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Trypsin Specificity as Elucidated by Lie Calculations, X-Ray Structures, and Association Constant Measurements Protein Sci., 13, 2004
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1UZ1
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![BU of 1uz1 by Molmil](/molmil-images/mine/1uz1) | Family 1 b-glucosidase from Thermotoga maritima in complex with isofagomine lactam | Descriptor: | (3S,4R,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)PIPERIDIN-2-ONE, BETA-GLUCOSIDASE A | Authors: | Gloster, T.M, Macdonald, J, Stick, R.V, Davies, G.J. | Deposit date: | 2004-03-03 | Release date: | 2004-11-23 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Common Inhibition of Both -Glucosidases and -Mannosidases by Isofagomine Lactam Reflects Different Conformational Itineraries for Pyranoside Hydrolysis Chembiochem, 5, 2004
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4US2
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![BU of 4us2 by Molmil](/molmil-images/mine/4us2) | The crystal structure of H-Ras and SOS in complex with ligands | Descriptor: | 3-[(3R)-1-ethyl-2,5-dioxopyrrolidin-3-yl]benzamide, GTPASE HRAS, SON OF SEVENLESS HOMOLOG 1 | Authors: | Winter, J.J.G, Anderson, M, Blades, K, Brassington, C, Breeze, A.L, Chresta, C, Embrey, K, Fairley, G, Faulder, P, Finlay, M.R.V, Kettle, J.G, Nowak, T, Overman, R, Patel, S.J, Perkins, P, Spadola, L, Tart, J, Tucker, J, Wrigley, G. | Deposit date: | 2014-07-02 | Release date: | 2015-03-04 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.48 Å) | Cite: | Small Molecule Binding Sites on the Ras:SOS Complex Can be Exploited for Inhibition of Ras Activation. J.Med.Chem., 58, 2015
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8AFE
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![BU of 8afe by Molmil](/molmil-images/mine/8afe) | |
1FU0
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![BU of 1fu0 by Molmil](/molmil-images/mine/1fu0) | CRYSTAL STRUCTURE ANALYSIS OF THE PHOSPHO-SERINE 46 HPR FROM ENTEROCOCCUS FAECALIS | Descriptor: | PHOSPHOCARRIER PROTEIN HPR | Authors: | Audette, G.F, Engelmann, R, Hengstenberg, W, Deutscher, J, Hayakawa, K, Quail, J.W, Delbaere, L.T.J. | Deposit date: | 2000-09-13 | Release date: | 2000-11-22 | Last modified: | 2022-12-21 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The 1.9 A resolution structure of phospho-serine 46 HPr from Enterococcus faecalis. J.Mol.Biol., 303, 2000
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8ATW
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![BU of 8atw by Molmil](/molmil-images/mine/8atw) | Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with 6-mer RNA, pppGpGpApApApU (IC6) | Descriptor: | DNA-directed RNA polymerase, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Goovaerts, Q, Shen, J, Patel, S.S, Das, K. | Deposit date: | 2022-08-24 | Release date: | 2023-08-30 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (3.62 Å) | Cite: | Structures illustrate step-by-step mitochondrial transcription initiation. Nature, 622, 2023
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8AJZ
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![BU of 8ajz by Molmil](/molmil-images/mine/8ajz) | Serial femtosecond crystallography structure of CO bound ba3- type cytochrome c oxidase at 2 milliseconds after irradiation by a 532 nm laser | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, CARBON MONOXIDE, COPPER (II) ION, ... | Authors: | Safari, C, Ghosh, S, Andersson, R, Johannesson, J, Donoso, A.V, Bath, P, Bosman, R, Dahl, P, Nango, E, Tanaka, R, Zoric, D, Svensson, E, Nakane, T, Iwata, S, Neutze, R, Branden, G. | Deposit date: | 2022-07-29 | Release date: | 2023-08-16 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Time-resolved serial crystallography to track the dynamics of carbon monoxide in the active site of cytochrome c oxidase. Sci Adv, 9, 2023
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8AFL
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![BU of 8afl by Molmil](/molmil-images/mine/8afl) | |
8ATT
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![BU of 8att by Molmil](/molmil-images/mine/8att) | Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex with 4-mer RNA, pppGpGpUpA (IC4) | Descriptor: | DNA-directed RNA polymerase, mitochondrial, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Goovaerts, Q, Shen, J, Patel, S.S, Das, K. | Deposit date: | 2022-08-24 | Release date: | 2023-08-30 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (3.44 Å) | Cite: | Structures illustrate step-by-step mitochondrial transcription initiation. Nature, 622, 2023
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1G2J
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![BU of 1g2j by Molmil](/molmil-images/mine/1g2j) | RNA OCTAMER R(CCCP*GGGG) CONTAINING PHENYL RIBONUCLEOTIDE | Descriptor: | 5'-R(*CP*CP*CP*(PYY)P*GP*GP*GP*G)-3', CALCIUM ION | Authors: | Minasov, G, Matulic-Adamic, J, Wilds, C.J, Haeberli, P, Usman, N, Beigelman, L, Egli, M. | Deposit date: | 2000-10-20 | Release date: | 2000-12-06 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Crystal structure of an RNA duplex containing phenyl-ribonucleotides, hydrophobic isosteres of the natural pyrimidines. RNA, 6, 2000
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6DW4
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![BU of 6dw4 by Molmil](/molmil-images/mine/6dw4) | SAMHD1 Bound to Cladribine-TP in the Catalytic Pocket and Allosteric Pocket | Descriptor: | 2'-deoxy-2-methyladenosine 5'-(tetrahydrogen triphosphate), Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Knecht, K.M, Buzovetsky, O, Schneider, C, Thomas, D, Srikanth, V, Kaderali, L, Tofoleanu, F, Reiss, K, Ferreiros, N, Geisslinger, G, Batista, V.S, Ji, X, Cinatl, J, Keppler, O.T, Xiong, Y. | Deposit date: | 2018-06-26 | Release date: | 2018-10-10 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1G0M
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![BU of 1g0m by Molmil](/molmil-images/mine/1g0m) | CRYSTAL STRUCTURE OF T4 LYSOZYME MUTANT T152I | Descriptor: | 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, PROTEIN (LYSOZYME) | Authors: | Xu, J, Baase, W.A, Quillin, M.L, Matthews, B.W. | Deposit date: | 2000-10-06 | Release date: | 2001-05-23 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural and thermodynamic analysis of the binding of solvent at internal sites in T4 lysozyme. Protein Sci., 10, 2001
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8AFM
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![BU of 8afm by Molmil](/molmil-images/mine/8afm) | |