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PDB: 179 件

4UOV
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The structure of a tetrameric alpha-carbonic anhydrase from Thermovibrio ammonificans reveals a core formed around intermolecular disulfides, which contribute to its thermostability.
分子名称: 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, ...
著者James, P, Isupov, M, Sayer, C, Berg, S, Lioliou, M, Kotlar, H, Littlechild, J.
登録日2014-06-10
公開日2014-10-15
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The Structure of a Tetrameric [Alpha]-Carbonic Anhydrase from Thermovibrio Ammonificans Reveals a Core Formed Around Intermolecular Disulfides that Contribute to its Thermostability
Acta Crystallogr.,Sect.D, 70, 2014
1A2Z
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PYRROLIDONE CARBOXYL PEPTIDASE FROM THERMOCOCCUS LITORALIS
分子名称: PYRROLIDONE CARBOXYL PEPTIDASE, SULFATE ION
著者Singleton, M.R, Isupov, M.N, Littlechild, J.A.
登録日1998-01-13
公開日1998-07-15
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献X-ray structure of pyrrolidone carboxyl peptidase from the hyperthermophilic archaeon Thermococcus litoralis.
Structure Fold.Des., 7, 1999
2V9P
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Crystal structure of papillomavirus E1 hexameric helicase DNA-free form
分子名称: MAGNESIUM ION, PHOSPHATE ION, REPLICATION PROTEIN E1
著者Sanders, C.M, Kovalevskiy, O.V, Sizov, D, Lebedev, A.A, Isupov, M.N, Antson, A.A.
登録日2007-08-24
公開日2007-10-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Papillomavirus E1 Helicase Assembly Maintains an Asymmetric State in the Absence of DNA and Nucleotide Cofactors.
Nucleic Acids Res., 35, 2007
2VIM
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X-ray structure of Fasciola hepatica thioredoxin
分子名称: THIOREDOXIN
著者Line, K, Isupov, M.N, Garcia-Rodriguez, E, Maggioli, G, Parra, F, Littlechild, J.A.
登録日2007-12-05
公開日2008-07-29
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献The Fasciola Hepatica Thioredoxin: High Resolution Structure Reveals Two Oxidation States.
Mol.Biochem.Parasitol., 161, 2008
2VXI
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The binding of heme and zinc in Escherichia coli Bacterioferritin
分子名称: BACTERIOFERRITIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION, ...
著者Willies, S.C, Isupov, M.N, Garman, E.F, Littlechild, J.A.
登録日2008-07-04
公開日2008-11-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献The Binding of Haem and Zinc in the 1.9 A X-Ray Structure of Escherichia Coli Bacterioferritin.
J.Biol.Inorg.Chem., 14, 2009
1HL7
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Gamma lactamase from an Aureobacterium species in complex with 3a,4,7,7a-tetrahydro-benzo [1,3] dioxol-2-one
分子名称: 3A,4,7,7A-TETRAHYDRO-BENZO [1,3] DIOXOL-2-ONE, GAMMA LACTAMASE
著者Line, K, Isupov, M.N, Littlechild, J.A.
登録日2003-03-14
公開日2004-03-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献The Crystal Structure of a (-)Gamma-Lactamase from an Aureobacterium Species Reveals a Tetrahedral Intermediate in the Active Site
J.Mol.Biol., 338, 2004
1HKH
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unligated gamma lactamase from an Aureobacterium species
分子名称: GAMMA LACTAMASE, SULFATE ION
著者Line, K, Isupov, M.N, Littlechild, J.A.
登録日2003-03-10
公開日2004-03-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献The crystal structure of a (-) gamma-lactamase from an Aureobacterium species reveals a tetrahedral intermediate in the active site.
J. Mol. Biol., 338, 2004
1QLW
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The Atomic Resolution Structure of a Novel Bacterial Esterase
分子名称: ESTERASE, SULFATE ION
著者Bourne, P.C, Isupov, M.N, Littlechild, J.A.
登録日1999-09-17
公開日2000-02-10
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (1.09 Å)
主引用文献The Atomic Resolution Structure of a Novel Bacterial Esterase
Structure, 8, 2000
8ORK
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cyclic 2,3-diphosphoglycerate synthetase from the hyperthermophilic archaeon Methanothermus fervidus
分子名称: 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, ...
著者De Rose, S.A, Isupov, M.
登録日2023-04-14
公開日2023-12-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Structural characterization of a novel cyclic 2,3-diphosphoglycerate synthetase involved in extremolyte production in the archaeon Methanothermus fervidus .
Front Microbiol, 14, 2023
8ORU
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cyclic 2,3-diphosphoglycerate synthetase from the hyperthermophilic archaeon Methanothermus fervidus bound to 2,3-diphosphoglycerate and ADP.
分子名称: (2R)-2,3-diphosphoglyceric acid, 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, ...
著者De Rose, S.A, Isupov, M.
登録日2023-04-17
公開日2023-12-06
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.23 Å)
主引用文献Structural characterization of a novel cyclic 2,3-diphosphoglycerate synthetase involved in extremolyte production in the archaeon Methanothermus fervidus .
Front Microbiol, 14, 2023
7QON
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Monoclinic triose phosphate isomerase from Fasciola hepatica.
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, SODIUM ION, ...
著者Kontellas, G, Isupov, M.N, Littlechild, J.A.
登録日2021-12-24
公開日2023-01-18
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Monoclinic triose phosphate isomerase from Fasciola hepatica.
To Be Published
7P7W
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N-acetylglucosamine kinase from Plesiomonas shigelloides compexed with alpha-N-acetylglucosamine and ADP
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, ...
著者Roy, S, Isupov, M.N, Harmer, N.J, Ames, J.R.
登録日2021-07-20
公開日2022-08-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases
J.Biol.Chem., 2022
7P7I
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Native structure of N-acetylglucosamine kinase from Plesiomonas shigelloides
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
著者Roy, S, Isupov, M.N, Harmer, N.J, Ames, J.R.
登録日2021-07-19
公開日2022-07-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases
J.Biol.Chem., 2022
7P9L
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N-acetylglucosamine kinase from Plesiomonas shigelloides compexed with alpha-N-acetylglucosamine-6-phosphate
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-6-O-phosphono-beta-D-glucopyranose, ...
著者Roy, S, Isupov, M.N, Harmer, N.J, Ames, J.R.
登録日2021-07-27
公開日2022-08-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases
J.Biol.Chem., 2022
7P9P
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N-acetylglucosamine kinase from Plesiomonas shigelloides compexed with alpha-N-acetylglucosamine and AMP-PNP inhibitor
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-glucopyranose, DI(HYDROXYETHYL)ETHER, ...
著者Roy, S, Isupov, M.N, Harmer, N.J, Ames, J.R.
登録日2021-07-27
公開日2022-08-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases
J.Biol.Chem., 2022
7P9Y
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N-acetylglucosamine kinase from Plesiomonas shigelloides compexed with alpha-N-acetylglucosamine
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-glucopyranose, ...
著者Roy, S, Isupov, M.N, Harmer, N.J, Ames, J.R.
登録日2021-07-28
公開日2022-08-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases
J.Biol.Chem., 2022
7PVI
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dTDP-sugar epimerase
分子名称: CITRATE ANION, SODIUM ION, alpha-D-xylopyranose, ...
著者Cross, A.R, Harmer, N.J, Isupov, M.N.
登録日2021-10-04
公開日2022-04-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.434 Å)
主引用文献Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases.
J.Biol.Chem., 298, 2022
7PWB
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dTDP-sugar epimerase from Coxiella burnetii in complex with dTDP
分子名称: 1,2-ETHANEDIOL, CITRIC ACID, THYMIDINE-5'-DIPHOSPHATE, ...
著者Cross, A.R, Harmer, N.J, Isupov, M.N.
登録日2021-10-06
公開日2022-04-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases.
J.Biol.Chem., 298, 2022
5I6J
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Crystal Structure of SRGAP2 F-BARx
分子名称: SLIT-ROBO Rho GTPase-activating protein 2
著者Sporny, M, Guez-Haddad, J, Isupov, M.N, Opatowsky, Y.
登録日2016-02-16
公開日2017-03-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural History of Human SRGAP2 Proteins.
Mol. Biol. Evol., 34, 2017
5I7D
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Crystal Structure of srGAP2 F-BARx WT Form-2
分子名称: SLIT-ROBO Rho GTPase-activating protein 2
著者Sporny, M, Guez-Haddad, J, Isupov, M.N, Opatowsky, Y.
登録日2016-02-17
公開日2017-08-30
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.95 Å)
主引用文献Structural Basis for srGAP2 Membrane Interactions, and Antagonism by the Human Specific Paralog srGAP2C
To Be Published
5FRD
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Structure of a thermophilic esterase
分子名称: CARBOXYLESTERASE (EST-2), CHLORIDE ION, CITRATE ANION, ...
著者Sayer, C, Finnigan, W, Isupov, M.N, Levisson, M, Kengen, S.W.M, van der Oost, J, Harmer, N, Littlechild, J.A.
登録日2015-12-17
公開日2016-05-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural and Biochemical Characterisation of Archaeoglobus Fulgidus Esterase Reveals a Bound Coa Molecule in the Vicinity of the Active Site.
Sci.Rep., 6, 2016
7PWI
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Structure of the dTDP-sugar epimerase StrM
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, dTDP-4-keto-rhamnose 3,5-epimerase,dTDP-4-dehydrorhamnose 3,5-epimerase
著者Cross, A.R, Harmer, N.J, Isupov, M.N.
登録日2021-10-06
公開日2022-04-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.326 Å)
主引用文献Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases.
J.Biol.Chem., 298, 2022
7PWH
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Structure of the dTDP-sugar epimerase StrM
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, THYMIDINE-5'-DIPHOSPHATE, ...
著者Cross, A.R, Harmer, N.J, Isupov, M.N.
登録日2021-10-06
公開日2022-04-20
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases.
J.Biol.Chem., 298, 2022
5FIP
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Discovery and characterization of a novel thermostable and highly halotolerant GH5 cellulase from an Icelandic hot spring isolate
分子名称: 1,2-ETHANEDIOL, 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE, CHLORIDE ION, ...
著者Zarafeta, D, Kissas, D, Sayer, C, Gudbergsdottir, S.R, Ladoukakis, E, Isupov, M.N, Chatziioannou, A, Peng, X, Littlechild, J.A, Skretas, G, Kolisis, F.N.
登録日2015-10-01
公開日2016-01-20
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Discovery and Characterization of a Thermostable and Highly Halotolerant Gh5 Cellulase from an Icelandic Hot Spring Isolate.
Plos One, 11, 2016
1W5T
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Structure of the Aeropyrum Pernix ORC2 protein (ADPNP-ADP complexes)
分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ORC2, ...
著者Singleton, M.R, Morales, R, Grainge, I, Cook, N, Isupov, M.N, Wigley, D.B.
登録日2004-08-09
公開日2004-10-05
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Conformational Changes Induced by Nucleotide Binding in Cdc6/Orc from Aeropyrum Pernix
J.Mol.Biol., 343, 2004

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