6H5S
 
 | | Cryo-EM map of in vitro assembled Measles virus N into nucleocapsid-like particles (NCLPs) bound to viral genomic 5-prime RNA hexamers. | | Descriptor: | Nucleocapsid, RNA (5'-R(*AP*CP*CP*AP*GP*A)-3') | | Authors: | Desfosses, A, Milles, S, Ringkjobing Jensen, M, Guseva, S, Colletier, J.P, Maurin, D, Schoehn, G, Gutsche, I, Ruigrok, R, Blackledge, M. | | Deposit date: | 2018-07-25 | | Release date: | 2019-06-12 | | Last modified: | 2024-05-15 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Assembly and cryo-EM structures of RNA-specific measles virus nucleocapsids provide mechanistic insight into paramyxoviral replication.
Proc.Natl.Acad.Sci.USA, 116, 2019
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8BHZ
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8B9F
 | | Structure of Echovirus 11 complexed with DAF (CD55) calculated from symmetry expansion | | Descriptor: | Complement decay-accelerating factor, Genome polyprotein, SPHINGOSINE | | Authors: | Stuart, D.I, Ren, J, Qin, L, Zhou, D. | | Deposit date: | 2022-10-05 | | Release date: | 2022-12-07 | | Last modified: | 2023-01-04 | | Method: | ELECTRON MICROSCOPY (3.93 Å) | | Cite: | Switching of Receptor Binding Poses between Closely Related Enteroviruses.
Viruses, 14, 2022
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6HXU
 | | Crystal structure of Human RHOB Q63L in complex with GTP | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rho-related GTP-binding protein RhoB | | Authors: | Soulie, S, Gence, R, Cabantous, S, Lajoie-Mazenc, I, Favre, G, Pedelacq, J.D. | | Deposit date: | 2018-10-18 | | Release date: | 2019-09-25 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.19 Å) | | Cite: | A Targeted Protein Degradation Cell-Based Screening for Nanobodies Selective toward the Cellular RHOB GTP-Bound Conformation.
Cell Chem Biol, 26, 2019
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5UM8
 | | Crystal structure of HIV-1 envelope trimer 16055 NFL TD CC (T569G) in complex with Fabs 35022 and PGT124 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 35022 heavy chain, ... | | Authors: | Garces, F, Stanfield, R.L, Wilson, I.A. | | Deposit date: | 2017-01-26 | | Release date: | 2017-05-24 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (3.935 Å) | | Cite: | Glycine Substitution at Helix-to-Coil Transitions Facilitates the Structural Determination of a Stabilized Subtype C HIV Envelope Glycoprotein.
Immunity, 46, 2017
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4F6R
 | | Tubulin:Stathmin-like domain complex | | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Designed ankyrin repeat protein (DARPIN) D2, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Gigant, B, Mignot, I, Knossow, M. | | Deposit date: | 2012-05-15 | | Release date: | 2012-07-18 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.64 Å) | | Cite: | Design and characterization of modular scaffolds for tubulin assembly.
J.Biol.Chem., 287, 2012
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4L59
 | | Crystal structure of the 3-MBT repeat domain of L3MBTL3 and UNC2533 complex | | Descriptor: | 4-(pyrrolidin-1-yl)-1-{4-[2-(pyrrolidin-1-yl)ethyl]phenyl}piperidine, Lethal(3)malignant brain tumor-like protein 3, SULFATE ION, ... | | Authors: | Zhong, N, Dong, A, Ravichandran, M, Camerino, M.A, Dickson, B.M, James, L.I, Baughman, B.M, Norris, J.L, Kireev, D.B, Janzen, W.P, Graslund, S, Frye, S.V, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Brown, P.J, Structural Genomics Consortium (SGC) | | Deposit date: | 2013-06-10 | | Release date: | 2013-07-10 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.29 Å) | | Cite: | The structure-activity relationships of L3MBTL3 inhibitors: flexibility of the dimer interface.
Medchemcomm, 4, 2013
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4L5H
 | | Structure of haze forming proteins in white wines: Vitis vinifera thaumatin-like proteins | | Descriptor: | GLYCEROL, VVTL1 | | Authors: | Marangon, M, Menz, R.I, Waters, E.J, Van Sluyter, S.C. | | Deposit date: | 2013-06-11 | | Release date: | 2013-07-03 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure of Haze Forming Proteins in White Wines: Vitis vinifera Thaumatin-Like Proteins.
Plos One, 9, 2014
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6A27
 | | Crystal structure of PprA W183R mutant form 1 | | Descriptor: | DNA repair protein PprA, GLYCEROL, SULFATE ION | | Authors: | Adachi, M, Shibazaki, C, Shimizu, R, Arai, S, Satoh, K, Narumi, I, Kuroki, R. | | Deposit date: | 2018-06-09 | | Release date: | 2018-12-26 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (1.353 Å) | | Cite: | Extended structure of pleiotropic DNA repair-promoting protein PprA from Deinococcus radiodurans.
FASEB J., 33, 2019
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3Q1E
 | | Crystal structure of Y116T/I16A double mutant of 5-hydroxyisourate hydrolase in complex with T4 | | Descriptor: | 3,5,3',5'-TETRAIODO-L-THYRONINE, 5-hydroxyisourate hydrolase | | Authors: | Cendron, L, Ramazzina, I, Percudani, R, Zanotti, G, Berni, R. | | Deposit date: | 2010-12-17 | | Release date: | 2011-05-04 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Probing the evolution of hydroxyisourate hydrolase into transthyretin through active-site redesign.
J.Mol.Biol., 409, 2011
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5L90
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8B8R
 | | Complex of Echovirus 11 with its attaching receptor decay-accelerating factor (CD55) | | Descriptor: | DECAY ACCELERATING FACTOR (CD55), SPHINGOSINE, VP1, ... | | Authors: | Stuart, D.I, Ren, J, Zhou, D, Qin, L. | | Deposit date: | 2022-10-04 | | Release date: | 2022-12-07 | | Last modified: | 2023-01-04 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Switching of Receptor Binding Poses between Closely Related Enteroviruses.
Viruses, 14, 2022
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6HNL
 | | Selenomethionine derivative of IdmH 96-104 loop truncation variant | | Descriptor: | Putative polyketide cyclase IdmH | | Authors: | Drulyte, I, Obajdin, J, Trinh, C, Hemsworth, G.R, Berry, A. | | Deposit date: | 2018-09-16 | | Release date: | 2019-11-06 | | Last modified: | 2019-11-20 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Crystal structure of the putative cyclase IdmH from the indanomycin nonribosomal peptide synthase/polyketide synthase.
Iucrj, 6, 2019
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4JMR
 | | A unique spumavirus gag N-terminal domain with functional properties of orthoretroviral Matrix and Capsid | | Descriptor: | Env protein, Gag protein | | Authors: | Taylor, I.A, Goldstone, D.C, Flower, T.G, Ball, N.J. | | Deposit date: | 2013-03-14 | | Release date: | 2013-05-29 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | A Unique Spumavirus Gag N-terminal Domain with Functional Properties of Orthoretroviral Matrix and Capsid.
Plos Pathog., 9, 2013
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5LAO
 | | S-nitrosylated 3D NMR structure of the cytoplasmic rhodanese domain of the inner membrane protein YgaP from Escherichia coli | | Descriptor: | Inner membrane protein YgaP | | Authors: | Eichmann, C, Tzitzilonis, C, Nakamura, T, Maslennikov, I, Kwiatkowski, W, Choe, S, Lipton, S.A, Guntert, P, Riek, R. | | Deposit date: | 2016-06-14 | | Release date: | 2016-08-17 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | S-Nitrosylation Induces Structural and Dynamical Changes in a Rhodanese Family Protein.
J.Mol.Biol., 428, 2016
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4JQO
 | | Crystal structure of anabolic ornithine carbamoyltransferase from Vibrio vulnificus in complex with citrulline and inorganic phosphate | | Descriptor: | CHLORIDE ION, CITRULLINE, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Shabalin, I.G, Winsor, J, Grimshaw, S, Domagalski, M.J, Anderson, W.F, Minor, W, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2013-03-20 | | Release date: | 2013-04-17 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.082 Å) | | Cite: | Crystal structures and kinetic properties of anabolic ornithine carbamoyltransferase from human pathogens Vibrio vulnificus and Bacillus anthracis
To be Published
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5VE6
 | | Crystal structure of Sugen kinase 223 | | Descriptor: | Tyrosine-protein kinase SgK223 | | Authors: | Patel, O, Lucet, I, Panjikar, S. | | Deposit date: | 2017-04-03 | | Release date: | 2017-10-18 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.953 Å) | | Cite: | Structure of SgK223 pseudokinase reveals novel mechanisms of homotypic and heterotypic association.
Nat Commun, 8, 2017
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4JRU
 | | Structure of haze forming proteins in white wines: Vitis vinifera thaumatin-like proteins | | Descriptor: | GLYCEROL, thaumatin-like protein | | Authors: | Marangon, M, Menz, R.I, Waters, E.J, Van Sluyter, S.C. | | Deposit date: | 2013-03-22 | | Release date: | 2014-04-02 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | Structure of Haze Forming Proteins in White Wines: Vitis vinifera Thaumatin-Like Proteins.
Plos One, 9, 2014
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5LAM
 | | Refined 3D NMR structure of the cytoplasmic rhodanese domain of the inner membrane protein YgaP from Escherichia coli | | Descriptor: | Inner membrane protein YgaP | | Authors: | Eichmann, C, Tzitzilonis, C, Nakamura, T, Maslennikov, I, Kwiatkowski, W, Choe, S, Lipton, S.A, Guntert, P, Riek, R. | | Deposit date: | 2016-06-14 | | Release date: | 2016-08-17 | | Last modified: | 2024-06-19 | | Method: | SOLUTION NMR | | Cite: | S-Nitrosylation Induces Structural and Dynamical Changes in a Rhodanese Family Protein.
J.Mol.Biol., 428, 2016
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4FDG
 | | Crystal Structure of an Archaeal MCM Filament | | Descriptor: | Minichromosome maintenance protein MCM, ZINC ION | | Authors: | Slaymaker, I.M, Fu, Y, Brewster, A.B, Chen, X.S. | | Deposit date: | 2012-05-28 | | Release date: | 2013-03-06 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (4.1 Å) | | Cite: | Mini-chromosome maintenance complexes form a filament to remodel DNA structure and topology.
Nucleic Acids Res., 41, 2013
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4FHE
 | | Spore photoproduct lyase C140A mutant | | Descriptor: | 1,2-ETHANEDIOL, IRON/SULFUR CLUSTER, SULFATE ION, ... | | Authors: | Benjdia, A, Heil, K, Barends, T.R.M, Carell, T, Schlichting, I. | | Deposit date: | 2012-06-06 | | Release date: | 2012-07-18 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural insights into recognition and repair of UV-DNA damage by Spore Photoproduct Lyase, a radical SAM enzyme.
Nucleic Acids Res., 40, 2012
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5LFD
 | | Crystal structure of allantoin racemase from Pseudomonas fluorescens AllR | | Descriptor: | Allantoin racemase | | Authors: | Cendron, l, Zanotti, G, Percudani, R, Ramazzina, I, Puggioni, V, Maccacaro, E, Liuzzi, A, Secchi, A. | | Deposit date: | 2016-07-01 | | Release date: | 2017-05-10 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | The Structure and Function of a Microbial Allantoin Racemase Reveal the Origin and Conservation of a Catalytic Mechanism.
Biochemistry, 55, 2016
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2XFS
 | | Structural and mechanistic studies on a cephalosporin esterase from the clavulanic acid biosynthesis pathway | | Descriptor: | (2R,3Z,5R)-3-(2-HYDROXYETHYLIDENE)-7-OXO-4-OXA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID, ORF12 | | Authors: | Iqbal, A, Valegard, K, Kershaw, N.J, Ivison, D, Genereux, C, Dubus, A, Andersson, I, Schofield, C.J. | | Deposit date: | 2010-05-26 | | Release date: | 2011-06-29 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural and mechanistic studies of the orf12 gene product from the clavulanic acid biosynthesis pathway.
Acta Crystallogr. D Biol. Crystallogr., 69, 2013
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3GFU
 | | FaeE-FaeG chaperone-major pilin complex of F4 ac 5/95 fimbriae | | Descriptor: | Chaperone protein faeE, FaeG, SULFATE ION | | Authors: | Van Molle, I, Moonens, K, Garcia-Pino, A, Buts, L, Bouckaert, J, De Greve, H. | | Deposit date: | 2009-02-27 | | Release date: | 2009-10-20 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.991 Å) | | Cite: | Structural and thermodynamic characterization of pre- and postpolymerization states in the F4 fimbrial subunit FaeG
J.Mol.Biol., 394, 2009
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3QKM
 | | Spirocyclic sulfonamides as AKT inhibitors | | Descriptor: | N-(2-ethoxyethyl)-N-{(2S)-2-hydroxy-3-[(5R)-2-(quinazolin-4-yl)-2,7-diazaspiro[4.5]dec-7-yl]propyl}-2,6-dimethylbenzenesulfonamide, RAC-alpha serine/threonine-protein kinase | | Authors: | Xu, R, Banka, A, Blake, J.F, Mitchell, I.S, Wallace, E.M, Gloor, S.L, Martinson, M, Risom, T, Gross, S.D, Morales, T, Vigers, G.P.A, Brandhuber, B.J, Skelton, N.J. | | Deposit date: | 2011-02-01 | | Release date: | 2011-04-06 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Discovery of spirocyclic sulfonamides as potent Akt inhibitors with exquisite selectivity against PKA.
Bioorg.Med.Chem.Lett., 21, 2011
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