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PDB: 17892 件
1E28
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Nonstandard peptide binding of HLA-B*5101 complexed with HIV immunodominant epitope KM2(TAFTIPSI)
分子名称: BETA-2 MICROGLOBULIN LIGHT CHAIN, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN HEAVY CHAIN, PEPTIDE
著者Maenaka, K, Maenaka, T, Tomiyama, H, Takiguchi, M, Stuart, D.I, Jones, E.Y.
登録日2000-05-18
公開日2000-09-12
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Nonstandard peptide binding revealed by crystal structures of HLA-B*5101 complexed with HIV immunodominant epitopes.
J Immunol., 165, 2000
7Q87
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Carboxypeptidase T with (S)-3-phenyllactic acid
分子名称: ALPHA-HYDROXY-BETA-PHENYL-PROPIONIC ACID, CALCIUM ION, Carboxypeptidase T, ...
著者Timofeev, V.I, Akparov, V.K, Shevtsov, M.B, Kuranova, I.P.
登録日2021-11-10
公開日2022-01-26
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Carboxypeptidase T with (S)-3-phenyllactic acid
To Be Published
7VUS
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BU of 7vus by Molmil
Crystal structure of AlleyCat9 with 5-nitro-benzotriazole
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 5-nitro-1H-benzotriazole, AlleyCat, ...
著者Tame, J.R.H, Korendovych, I.V, Margheritis, E, Takahashi, K.
登録日2021-11-04
公開日2022-07-27
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献NMR-guided directed evolution.
Nature, 610, 2022
7VUR
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Crystal structure of AlleyCat9 with calcium but no inhibitor
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, AlleyCat, CALCIUM ION
著者Margheritis, E, Takahashi, K, Korendovych, I.V, Tame, J.R.H.
登録日2021-11-04
公開日2022-07-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献NMR-guided directed evolution.
Nature, 610, 2022
5KUY
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BU of 5kuy by Molmil
Influenza hemagglutinin H3 A/Hong Kong/1/1968 in complex with designed inhibitor protein HSB.2A
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Designed influenza inhibitor HSB.2A, ...
著者Bernard, S.M, Wilson, I.A.
登録日2016-07-13
公開日2017-06-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.598 Å)
主引用文献Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site.
Nat. Biotechnol., 35, 2017
7VUU
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BU of 7vuu by Molmil
Crystal structure of AlleyCat10 with inhibitor
分子名称: 5-nitro-1H-benzotriazole, AlleyCat, CALCIUM ION
著者Tame, J.R.H, Korendovych, I.V, Margheritis, E, Takahashi, K.
登録日2021-11-04
公開日2022-07-27
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献NMR-guided directed evolution.
Nature, 610, 2022
8T1C
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BU of 8t1c by Molmil
Cryo-EM structure of human TRPV4 ankyrin repeat domain in complex with GTPase RhoA
分子名称: GUANOSINE-5'-DIPHOSPHATE, Transforming protein RhoA, Transient receptor potential cation channel subfamily V member 4-Enhanced green fluorescent protein chimera
著者Nadezhdin, K.D, Talyzina, I.A, Neuberger, A, Sobolevsky, A.I.
登録日2023-06-02
公開日2023-07-05
実験手法ELECTRON MICROSCOPY (3.49 Å)
主引用文献Structure of human TRPV4 in complex with GTPase RhoA.
Nat Commun, 14, 2023
6GZH
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BU of 6gzh by Molmil
Crystal Structure of Human CDK9/cyclinT1 with A86
分子名称: Cyclin-T1, Cyclin-dependent kinase 9, GLYCEROL, ...
著者Ben-neriah, Y, Venkatachalam, A, Minzel, W, Fink, A, Snir-Alkalay, I, Vacca, J.
登録日2018-07-04
公開日2018-08-29
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.17 Å)
主引用文献Small Molecules Co-targeting CKI alpha and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models.
Cell, 175, 2018
7VUT
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BU of 7vut by Molmil
Crystal structure of AlleyCat10
分子名称: AlleyCat10, CALCIUM ION
著者Tame, J.R.H, Korendovych, I.V, Margheritis, E, Takahashi, K.
登録日2021-11-04
公開日2022-07-27
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献NMR-guided directed evolution.
Nature, 610, 2022
7SH1
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BU of 7sh1 by Molmil
Class II UvrA protein - Ecm16
分子名称: ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Excinuclease ABC subunit UvrA, ...
著者Grade, P, Erlandson, A, Ullah, A, Mathews, I.I, Chen, X, Kim, C.-Y, Mera, P.E.
登録日2021-10-07
公開日2022-10-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Structural and functional analyses of the echinomycin resistance conferring protein Ecm16 from Streptomyces lasalocidi.
Sci Rep, 13, 2023
5OGA
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BU of 5oga by Molmil
Structure of minimal i-motif domain
分子名称: DNA (5'-D(*TP*(DCP)P*GP*TP*TP*CP*(DCP)P*GP*TP*TP*TP*TP*TP*CP*GP*TP*TP*CP*CP*GP*T)-3')
著者Mir, B, Serrano, I, Buitrago, D, Orozco, M, Escaja, N, Gonzalez, C.
登録日2017-07-12
公開日2017-11-29
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Prevalent Sequences in the Human Genome Can Form Mini i-Motif Structures at Physiological pH.
J. Am. Chem. Soc., 139, 2017
7SEH
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BU of 7seh by Molmil
Glucose-6-phosphate 1-dehydrogenase (K403QdLtL)
分子名称: Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Mathews, I.I, Garcia, A.A, Wakatsuki, S, Mochly-Rosen, D.
登録日2021-09-30
公開日2022-08-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Stabilization of glucose-6-phosphate dehydrogenase oligomers enhances catalytic activity and stability of clinical variants.
J.Biol.Chem., 298, 2022
7SEI
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BU of 7sei by Molmil
Glucose-6-phosphate 1-dehydrogenase (K403Q)
分子名称: Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Mathews, I.I, Garcia, A.A, Wakatsuki, S, Mochly-Rosen, D.
登録日2021-09-30
公開日2022-08-17
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.65 Å)
主引用文献Stabilization of glucose-6-phosphate dehydrogenase oligomers enhances catalytic activity and stability of clinical variants.
J.Biol.Chem., 298, 2022
6WGI
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BU of 6wgi by Molmil
Atomic model of the mutant OCCM (ORC-Cdc6-Cdt1-Mcm2-7 with Mcm6 WHD truncation) loaded on DNA at 10.5 A resolution
分子名称: Cell division control protein 6, Cell division cycle protein CDT1, DNA (34-MER), ...
著者Yuan, Z, Schneider, S, Dodd, T, Riera, A, Bai, L, Yan, C, Magdalou, I, Ivanov, I, Stillman, B, Li, H, Speck, C.
登録日2020-04-05
公開日2020-07-15
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (10 Å)
主引用文献Structural mechanism of helicase loading onto replication origin DNA by ORC-Cdc6.
Proc.Natl.Acad.Sci.USA, 117, 2020
1AJF
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BU of 1ajf by Molmil
SOLUTION STRUCTURE OF THE P5B STEM LOOP FROM A GROUP I INTRON COMPLEXED WITH COBALT (III) HEXAMMINE, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: COBALT HEXAMMINE(III), RNA (5'-R(*GP*AP*CP*AP*GP*GP*GP*GP*AP*AP*AP*CP*UP*UP*UP*GP*UP*C)-3')
著者Kieft, J.S, Tinoco Junior, I.
登録日1997-05-02
公開日1997-07-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of a metal-binding site in the major groove of RNA complexed with cobalt (III) hexammine.
Structure, 5, 1997
2NNP
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BU of 2nnp by Molmil
Crystal structure analysis of HIV-1 protease mutant I84V with a inhibitor saquinavir
分子名称: (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, ACETIC ACID, GLYCEROL, ...
著者Tie, Y, Kovalevsky, A.Y, Boross, P, Wang, Y.F, Ghosh, A.K, Tozser, J, Harrison, R.W, Weber, I.T.
登録日2006-10-24
公開日2007-03-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Atomic resolution crystal structures of HIV-1 protease and mutants V82A and I84V with saquinavir.
Proteins, 67, 2007
2YM8
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BU of 2ym8 by Molmil
Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors
分子名称: (R)-5-(8-CHLOROISOQUINOLIN-3-YLAMINO)-3-(1-(DIMETHYLAMINO)PROPAN-2-YLOXY)PYRAZINE-2-CARBONITRILE, 1,2-ETHANEDIOL, SERINE/THREONINE-PROTEIN KINASE CHK1
著者Reader, J.C, Matthews, T.P, Klair, S, Cheung, K.M.J, Scanlon, J, Proisy, N, Addison, G, Ellard, J, Piton, N, Taylor, S, Cherry, M, Fisher, M, Boxall, K, Burns, S, Walton, M.I, Westwood, I.M, Hayes, A, Eve, P, Valenti, M, Brandon, A.H, Box, G, vanMontfort, R.L.M, Williams, D.H, Aherne, G.W, Raynaud, F.I, Eccles, S.A, Garrett, M.D, Collins, I.
登録日2011-06-06
公開日2012-01-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Structure-Guided Evolution of Potent and Selective Chk1 Inhibitors Through Scaffold Morphing.
J.Med.Chem., 54, 2011
1TL5
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Solution structure of apoHAH1
分子名称: Copper transport protein ATOX1
著者Anastassopoulou, I, Banci, L, Bertini, I, Cantini, F, Katsari, E, Rosato, A, Structural Proteomics in Europe (SPINE)
登録日2004-06-09
公開日2004-10-26
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution Structure of the Apo and Copper(I)-Loaded Human Metallochaperone HAH1.
Biochemistry, 43, 2004
6JFD
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BU of 6jfd by Molmil
K1U bound crystal structure of class I type b peptide deformylase from Pseudomonas aeruginosa
分子名称: (3R)-3-benzyl-4-oxo-4-[(2-oxo-2-phenylethyl)sulfanyl]butanoic acid, NICKEL (II) ION, Peptide deformylase
著者Lee, I.H, Ho, T.H, Kang, L.W.
登録日2019-02-08
公開日2020-02-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献K1U bound crystal structure of class I type b peptide deformylase from Pseudomonas aeruginosa
To be published
2NEF
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HIV-1 NEF (REGULATORY FACTOR), NMR, 40 STRUCTURES
分子名称: NEGATIVE FACTOR (F-PROTEIN)
著者Grzesiek, S, Bax, A, Clore, G.M, Gronenborn, A.M, Hu, J.S, Kaufman, J, Palmer, I, Stahl, S.J, Tjandra, N, Wingfield, P.T.
登録日1997-02-12
公開日1997-07-07
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Refined solution structure and backbone dynamics of HIV-1 Nef.
Protein Sci., 6, 1997
6JFA
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Met-Ala-Ser bound crystal structure of class I type b peptide deformylase from Pseudomonas aeruginosa
分子名称: MET-ALA-SER, NICKEL (II) ION, Peptide deformylase
著者Lee, I.H, Ho, T.H, Kang, L.W.
登録日2019-02-08
公開日2020-02-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Met-Ala-Ser bound crystal structure of class I type b peptide deformylase from Pseudomonas aeruginosa
To be published
6JFF
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K3U bound crystal structure of class I type b peptide deformylase from Pseudomonas aeruginosa
分子名称: NICKEL (II) ION, Peptide deformylase, S-(2-oxo-2-phenylethyl) (2R)-2-benzyl-4,4,4-trifluorobutanethioate
著者Lee, I.H, Ho, T.H, Kang, L.W.
登録日2019-02-08
公開日2020-02-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献K3U bound crystal structure of class I type b peptide deformylase from Pseudomonas aeruginosa
To be published
6T6M
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Y201W mutant of the orange carotenoid protein from Synechocystis at pH 5.5
分子名称: GLYCEROL, HISTIDINE, Orange carotenoid-binding protein, ...
著者Sluchanko, N.N, Gushchin, I, Botnarevskiy, V.S, Slonimskiy, Y.B, Remeeva, A, Kovalev, K, Stepanov, A.V, Gordeliy, V, Maksimov, E.G.
登録日2019-10-18
公開日2020-11-18
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.49 Å)
主引用文献Role of hydrogen bond alternation and charge transfer states in photoactivation of the Orange Carotenoid Protein.
Commun Biol, 4, 2021
1B5P
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THERMUS THERMOPHILUS ASPARTATE AMINOTRANSFERASE DOUBLE MUTANT 1
分子名称: PHOSPHATE ION, PROTEIN (ASPARTATE AMINOTRANSFERASE), PYRIDOXAL-5'-PHOSPHATE
著者Ura, H, Nakai, T, Kawaguchi, S.I, Miyahara, I, Hirotsu, K, Kuramitsu, S.
登録日1999-01-07
公開日2003-09-02
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Substrate recognition mechanism of thermophilic dual-substrate enzyme
J.BIOCHEM.(TOKYO), 130, 2001
6JFE
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K2U bound crystal structure of class I type b peptide deformylase from Pseudomonas aeruginosa
分子名称: NICKEL (II) ION, Peptide deformylase, S-(2-oxo-2-phenylethyl) (2R)-2-benzyl-4,4,4-trifluorobutanethioate
著者Lee, I.H, Ho, T.H, Kang, L.W.
登録日2019-02-08
公開日2020-02-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献K2U bound crystal structure of class I type b peptide deformylase from Pseudomonas aeruginosa
To be published

224931

件を2024-09-11に公開中

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