3K34
| Human carbonic anhydrase II with a sulfonamide inhibitor | 分子名称: | (4-SULFAMOYL-PHENYL)-THIOCARBAMIC ACID O-(2-THIOPHEN-3-YL-ETHYL) ESTER, 4-(HYDROXYMERCURY)BENZOIC ACID, Carbonic anhydrase 2, ... | 著者 | Behnke, C.A, Le Trong, I, Merritt, E.A, Teller, D.C, Stenkamp, R.E. | 登録日 | 2009-10-01 | 公開日 | 2010-05-12 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (0.9 Å) | 主引用文献 | Atomic resolution studies of carbonic anhydrase II. Acta Crystallogr.,Sect.D, 66, 2010
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1VJ9
| Urokinase Plasminogen Activator B-Chain-JT464 Complex | 分子名称: | N-(BENZYLSULFONYL)-L-SERYL-N~1~-{4-[AMINO(IMINO)METHYL]BENZYL}-O-BENZYL-L-SERINAMIDE, SULFATE ION, plasminogen activator, ... | 著者 | Schweinitz, A, Steinmetzer, T, Banke, I.J, Arlt, M.J.E, Stuerzebecher, A, Schuster, O, Geissler, A, Giersiefen, H, Zeslawska, E, Jacob, U, Kruger, A, Stuerzebecher, J. | 登録日 | 2004-02-03 | 公開日 | 2004-06-22 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Design of novel and selective inhibitors of urokinase-type plasminogen activator with improved pharmacokinetic properties for use as antimetastatic agents J.Biol.Chem., 279, 2004
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5TNU
| S. tokodaii XPB II crystal structure at 3.0 Angstrom resolution | 分子名称: | CHLORIDE ION, DNA-dependent ATPase XPBII, GLYCEROL, ... | 著者 | DuPrez, K.T, Hilario, E, Wang, I, Fan, L. | 登録日 | 2016-10-14 | 公開日 | 2017-11-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | 主引用文献 | Application of Electrochemical Devices to Characterize the Dynamic Actions of Helicases on DNA. Anal.Chem., 90, 2018
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1W2U
| X-RAY CRYSTAL STRUCTURE OF THE CATALYTIC DOMAIN OF HUMICOLA GRISEA CEL12A IN COMPLEX WITH A SOAKED THIO CELLOTETRAOSE | 分子名称: | ENDOGLUCANASE, SULFATE ION, TETRAETHYLENE GLYCOL, ... | 著者 | Berglund, G.I, Shaw, A, Stahlberg, J, Kenne, L, Driguez, T.H, Mitchinson, C, Sandgren, M. | 登録日 | 2004-07-08 | 公開日 | 2004-09-16 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | 主引用文献 | Crystal Complex Structures Reveal How Substrate is Bound in the -4 to the +2 Binding Sites of Humicola Grisea Cel12A J.Mol.Biol., 342, 2004
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1W3F
| Crystal structure of the hemolytic lectin from the mushroom Laetiporus sulphureus complexed with N-acetyllactosamine in the gamma motif | 分子名称: | GLYCEROL, HEMOLYTIC LECTIN FROM LAETIPORUS SULPHUREUS, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-alpha-D-glucopyranose | 著者 | Mancheno, J.M, Tateno, H, Goldstein, I.J, Martinez-Ripoll, M, Hermoso, J.A. | 登録日 | 2004-07-15 | 公開日 | 2005-02-01 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Structural Analysis of the Laetiporus Sulphureus Hemolytic Pore-Forming Lectin in Complex with Sugars J.Biol.Chem., 280, 2005
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6EVI
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1W3V
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1W03
| Isopenicillin N Synthase Aminoadipoyl-Cysteinyl-Glycine-Fe Complex | 分子名称: | DELTA-(L-ALPHA-AMINOADIPOYL)-L-CYSTEINYL-GLYCINE, FE (II) ION, ISOPENICILLIN N SYNTHETASE, ... | 著者 | Long, A.J, Clifton, I.J, Rutledge, P.J. | 登録日 | 2004-06-01 | 公開日 | 2005-05-04 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Studies on the Reaction of Isopenicillin N Synthase with the Truncated Substrate Analogues Delta-(L-Alpha-Aminoadipoyl)-L-Cysteinyl-Glycine and Delta-(L-Alpha-Aminoadipoyl)-L-Cysteinyl-D- Alanine Biochemistry, 44, 2005
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1W05
| Isopenicillin N Synthase Aminoadipoyl-Cysteinyl-Alanine-Fe Complex | 分子名称: | DELTA-(L-ALPHA-AMINOADIPOYL)-L-CYSTEINYL-D-ALANINE, FE (II) ION, ISOPENICILLIN N SYNTHETASE, ... | 著者 | Long, A.J, Clifton, I.J, Rutledge, P.J. | 登録日 | 2004-06-01 | 公開日 | 2005-05-04 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | Structural Studies on the Reaction of Isopenicillin N Synthase with the Truncated Substrate Analogues Delta-(L-Alpha-Aminoadipoyl)-L-Cysteinyl-Glycine and Delta-(L-Alpha-Aminoadipoyl)-L-Cysteinyl-D- Alanine Biochemistry, 44, 2005
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1MEX
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1MA3
| Structure of a Sir2 enzyme bound to an acetylated p53 peptide | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cellular tumor antigen p53, Transcriptional regulatory protein, ... | 著者 | Avalos, J.L, Celic, I, Muhammad, S, Cosgrove, M.S, Boeke, J.D, Wolberger, C. | 登録日 | 2002-07-31 | 公開日 | 2002-10-16 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of a Sir2 enzyme bound to an acetylated p53 peptide Mol.Cell, 10, 2002
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3KAQ
| Flavodoxin from D. desulfuricans (semireduced form) | 分子名称: | FLAVIN MONONUCLEOTIDE, Flavodoxin | 著者 | Romero, A, Caldeira, J, LeGall, J, Moura, I, Moura, J.J.G, Romao, M.J. | 登録日 | 2009-10-19 | 公開日 | 2009-11-24 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Crystal structure of flavodoxin from Desulfovibrio desulfuricans ATCC 27774 in two oxidation states. Eur.J.Biochem., 239, 1996
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1MG7
| Crystal Structure of xol-1 | 分子名称: | early switch protein xol-1 2.2k splice form | 著者 | Luz, J.G, Hassig, C.A, Godzik, A, Meyer, B.J, Wilson, I.A. | 登録日 | 2002-08-14 | 公開日 | 2003-04-22 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators Genes Dev., 17, 2003
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3UGT
| Crystal structure of the yeast mitochondrial threonyl-tRNA synthetase - orthorhombic crystal form | 分子名称: | Threonyl-tRNA synthetase, mitochondrial, ZINC ION | 著者 | Peterson, K.M, Ling, J, Simonovic, I, Cho, C, Soll, D, Simonovic, M. | 登録日 | 2011-11-02 | 公開日 | 2012-02-22 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Yeast mitochondrial threonyl-tRNA synthetase recognizes tRNA isoacceptors by distinct mechanisms and promotes CUN codon reassignment. Proc.Natl.Acad.Sci.USA, 109, 2012
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1W04
| Isopenicillin N Synthase Aminoadipoyl-Cysteinyl-Glycine-Fe-NO Complex | 分子名称: | DELTA-(L-ALPHA-AMINOADIPOYL)-L-CYSTEINYL-GLYCINE, FE (II) ION, HYDROXYAMINE, ... | 著者 | Long, A.J, Clifton, I.J, Rutledge, P.J. | 登録日 | 2004-06-01 | 公開日 | 2005-05-04 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | 主引用文献 | Structural Studies on the Reaction of Isopenicillin N Synthase with the Truncated Substrate Analogues Delta-(L-Alpha-Aminoadipoyl)-L-Cysteinyl-Glycine and Delta-(L-Alpha-Aminoadipoyl)-L-Cysteinyl-D- Alanine Biochemistry, 44, 2005
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1W06
| Isopenicillin N Synthase Aminoadipoyl-Cysteinyl-Alanine-Fe NO Complex | 分子名称: | DELTA-(L-ALPHA-AMINOADIPOYL)-L-CYSTEINYL-D-ALANINE, FE (II) ION, HYDROXYAMINE, ... | 著者 | Long, A.J, Clifton, I.J, Rutledge, P.J. | 登録日 | 2004-06-01 | 公開日 | 2005-05-04 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural Studies on the Reaction of Isopenicillin N Synthase with the Truncated Substrate Analogues Delta-(L-Alpha-Aminoadipoyl)-L-Cysteinyl-Glycine and Delta-(L-Alpha-Aminoadipoyl)-L-Cysteinyl-D- Alanine Biochemistry, 44, 2005
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3ZUI
| OMCI in complex with palmitoleic acid | 分子名称: | COMPLEMENT INHIBITOR, PALMITOLEIC ACID | 著者 | Roversi, P, Maillet, I, Togbe, D, Couillin, I, Quesniaux, V.F.J, Teixeira, M, Ahmat, N, Lissina, O, Boland, W, Ploss, K, Caesar, J.J.E, Leonhartsberger, S, Ryffel, B, Lea, S.M, Nunn, M.A. | 登録日 | 2011-07-19 | 公開日 | 2012-08-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Bifunctional Lipocalin Ameliorates Murine Immune Complex-Induced Acute Lung Injury. J.Biol.Chem., 288, 2013
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4CN1
| GlgE isoform 1 from Streptomyces coelicolor D394A mutant with maltose- 1-phosphate bound | 分子名称: | ALPHA-1,4-GLUCAN: MALTOSE-1-PHOSPHATE MALTOSYLTRANSFERASE 1, alpha-D-glucopyranose-(1-4)-1-O-phosphono-alpha-D-glucopyranose | 著者 | Syson, K, Stevenson, C.E.M, Rashid, A.M, Saalbach, G, Tang, M, Tuukanen, A, Svergun, D.I, Withers, S.G, Lawson, D.M, Bornemann, S. | 登録日 | 2014-01-21 | 公開日 | 2014-05-21 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Structural Insight Into How Streptomyces Coelicolor Maltosyl Transferase Glge Binds Alpha-Maltose 1-Phosphate and Forms a Maltosyl-Enzyme Intermediate. Biochemistry, 53, 2014
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3ZSO
| Small molecule inhibitors of the LEDGF site of HIV type 1 integrase identified by fragment screening and structure based design | 分子名称: | 5-{[(2-{[bis(4-methoxyphenyl)methyl]carbamoyl}benzyl)(prop-2-en-1-yl)amino]methyl}-1,3-benzodioxole-4-carboxylic acid, ACETIC ACID, INTEGRASE, ... | 著者 | Peat, T.S, Newman, J, Rhodes, D.I, Deadman, J.J, Vandergraaff, N, Le, G, Jones, E.D, Smith, J.A, Coates, J.A.V, Thienthong, N, Dolezal, O, Ryan, J.H, Savage, G.P, Francis, C.L. | 登録日 | 2011-06-30 | 公開日 | 2012-07-11 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Small Molecule Inhibitors of the Ledgf Site of Human Immunodeficiency Virus Integrase Identified by Fragment Screening and Structure Based Design. Plos One, 7, 2012
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3JVW
| HIV-1 Protease Mutant G86A with symmetric inhibitor DMP323 | 分子名称: | Gag-Pol polyprotein, [4-R-(-4-ALPHA,5-ALPHA,6-BETA,7-BETA)]-HEXAHYDRO-5,6-BIS(HYDROXY)-[1,3-BIS([4-HYDROXYMETHYL-PHENYL]METHYL)-4,7-BIS(PHEN YLMETHYL)]-2H-1,3-DIAZEPINONE | 著者 | Tie, Y, Weber, I.T. | 登録日 | 2009-09-17 | 公開日 | 2009-12-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Highly conserved glycine 86 and arginine 87 residues contribute differently to the structure and activity of the mature HIV-1 protease Proteins, 78, 2009
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3T1T
| MglA bound to GDP in P1 tetrameric arrangement | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Gliding protein mglA | 著者 | Miertzschke, M, Vetter, I.R, Koerner, C, Wittinghofer, A. | 登録日 | 2011-07-22 | 公開日 | 2011-08-31 | 最終更新日 | 2011-11-02 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural analysis of the Ras-like G protein MglA and its cognate GAP MglB and implications for bacterial polarity. Embo J., 30, 2011
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3JW2
| HIV-1 Protease Mutant G86S with DARUNAVIR | 分子名称: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, CHLORIDE ION, Gag-Pol polyprotein, ... | 著者 | Tie, Y, Weber, I.T. | 登録日 | 2009-09-17 | 公開日 | 2009-12-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Highly conserved glycine 86 and arginine 87 residues contribute differently to the structure and activity of the mature HIV-1 protease Proteins, 78, 2009
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1W35
| FERREDOXIN-NADP+ REDUCTASE (MUTATION: Y 303 W) | 分子名称: | FERREDOXIN-NADP+ REDUCTASE, FLAVIN-ADENINE DINUCLEOTIDE, SULFATE ION | 著者 | Hermoso, J.A, Perez-Dorado, I, Medina, M, Julvez, M.M, Sanz-Aparicio, J, Gomez-Moreno, C. | 登録日 | 2004-07-13 | 公開日 | 2005-07-26 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | C-Terminal Tyrosine of Ferredoxin-Nadp(+) Reductase in Hydride Transfer Processes with Nad(P)(+)/H. Biochemistry, 44, 2005
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1JI9
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2CA0
| Crystal structure of YC-17-bound cytochrome P450 PikC (CYP107L1) | 分子名称: | 4-{[4-(DIMETHYLAMINO)-3-HYDROXY-6-METHYLTETRAHYDRO-2H-PYRAN-2-YL]OXY}-12-ETHYL-3,5,7,11-TETRAMETHYLOXACYCLODODEC-9-ENE-2,8-DIONE, CYTOCHROME P450 MONOOXYGENASE, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Yermalitskaya, L.I, Kim, Y, Sherman, D.H, Waterman, M.R, Podust, L.M. | 登録日 | 2005-12-15 | 公開日 | 2006-12-13 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Crystal Structure of Yc-17-Bound Cytochrome P450 Pikc (Cyp107L1) To be Published
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