3K9F
| Detailed structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases | 分子名称: | (3S)-9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid, DNA (5'-D(*AP*CP*CP*AP*AP*GP*GP*T*CP*AP*TP*GP*AP*AP*T)-3'), DNA (5'-D(*CP*TP*GP*TP*TP*TP*TP*A*CP*GP*TP*GP*CP*AP*T)-3'), ... | 著者 | Laponogov, I, Pan, X.-S, Veselkov, D.A, Fisher, L.M, Sanderson, M.R. | 登録日 | 2009-10-15 | 公開日 | 2009-10-27 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural Basis of Gate-DNA Breakage and Resealing by Type II Topoisomerases Plos One, 5, 2010
|
|
3GBN
| Crystal Structure of Fab CR6261 in Complex with the 1918 H1N1 influenza virus hemagglutinin | 分子名称: | 1,2-ETHANEDIOL, 2-ETHOXYETHANOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Ekiert, D.C, Elsliger, M.A, Wilson, I.A. | 登録日 | 2009-02-20 | 公開日 | 2009-03-10 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Antibody recognition of a highly conserved influenza virus epitope. Science, 324, 2009
|
|
5H5T
| |
5HW5
| |
1WWL
| Crystal structure of CD14 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Monocyte differentiation antigen CD14 | 著者 | Kim, J.-I, Lee, C.J, Jin, M.S, Lee, C.-H, Paik, S.-G, Lee, H, Lee, J.-O. | 登録日 | 2005-01-06 | 公開日 | 2005-02-22 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal Structure of CD14 and Its Implications for Lipopolysaccharide Signaling J.Biol.Chem., 280, 2005
|
|
2H41
| |
6Z3Y
| |
1AMN
| TRANSITION STATE ANALOG: ACETYLCHOLINESTERASE COMPLEXED WITH M-(N,N,N-TRIMETHYLAMMONIO)TRIFLUOROACETOPHENONE | 分子名称: | ACETYLCHOLINESTERASE, M-(N,N,N-TRIMETHYLAMMONIO)-2,2,2-TRIFLUORO-1,1-DIHYDROXYETHYLBENZENE, SULFATE ION | 著者 | Harel, M, Silman, I, Sussman, J.L. | 登録日 | 1996-02-13 | 公開日 | 1996-04-03 | 最終更新日 | 2021-06-02 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | The X-ray structure of a transition state analog complex reveals the molecular origins of the catalytic power and substrate specificity of acetylcholinesterase. J.Am.Chem.Soc., 118, 1996
|
|
5IXM
| The LPS Transporter LptDE from Yersinia pestis, core complex | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, LPS-assembly lipoprotein LptE, LPS-assembly protein LptD | 著者 | Botos, I, Mayclin, S.J, McCarthy, J.G, Buchanan, S.K. | 登録日 | 2016-03-23 | 公開日 | 2016-05-18 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.746 Å) | 主引用文献 | Structural and Functional Characterization of the LPS Transporter LptDE from Gram-Negative Pathogens. Structure, 24, 2016
|
|
6Z06
| Crystal structure of Puumala virus Gc in complex with Fab 4G2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein, Fab 4G2 Heavy chain, ... | 著者 | Rissanen, I.R, Stass, R, Krumm, S.A, Seow, J, Hulswit, R.J.G, Paesen, G.C, Hepojoki, J, Vapalahti, O, Lundkvist, A, Reynard, O, Volchkov, V, Doores, K.J, Huiskonen, J.T, Bowden, T.A. | 登録日 | 2020-05-07 | 公開日 | 2020-12-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Molecular rationale for antibody-mediated targeting of the hantavirus fusion glycoprotein. Elife, 9, 2020
|
|
3J81
| CryoEM structure of a partial yeast 48S preinitiation complex | 分子名称: | 18S rRNA, MAGNESIUM ION, METHIONINE, ... | 著者 | Hussain, T, Llacer, J.L, Fernandez, I.S, Savva, C.G, Ramakrishnan, V. | 登録日 | 2014-08-29 | 公開日 | 2014-11-05 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structural changes enable start codon recognition by the eukaryotic translation initiation complex. Cell(Cambridge,Mass.), 159, 2014
|
|
1AKD
| CYTOCHROME P450CAM FROM PSEUDOMONAS PUTIDA, COMPLEXED WITH 1S-CAMPHOR | 分子名称: | CAMPHOR, CYTOCHROME P450CAM, POTASSIUM ION, ... | 著者 | Schlichting, I, Jung, C, Schulze, H. | 登録日 | 1997-05-16 | 公開日 | 1997-11-19 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of cytochrome P-450cam complexed with the (1S)-camphor enantiomer. FEBS Lett., 415, 1997
|
|
5HTS
| Crystal structure of shaft pilin spaA from Lactobacillus rhamnosus GG - D295N mutant | 分子名称: | Cell surface protein SpaA | 著者 | Chaurasia, P, Pratap, S, von Ossowski, I, Palva, A, Krishnan, V. | 登録日 | 2016-01-27 | 公開日 | 2016-07-20 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | New insights about pilus formation in gut-adapted Lactobacillus rhamnosus GG from the crystal structure of the SpaA backbone-pilin subunit Sci Rep, 6, 2016
|
|
6YUX
| Crystal structure of Malus domestica Double Bond Reductase (MdDBR) ternary complex | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 3-(4-HYDROXY-3-METHOXYPHENYL)-2-PROPENOIC ACID, ... | 著者 | Caliandro, R, Polsinelli, I, Demitri, N, Benini, S. | 登録日 | 2020-04-27 | 公開日 | 2021-02-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | The structural and functional characterization of Malus domestica double bond reductase MdDBR provides insights towards the identification of its substrates. Int.J.Biol.Macromol., 171, 2021
|
|
5FQF
| The details of glycolipid glycan hydrolysis by the structural analysis of a family 123 glycoside hydrolase from Clostridium perfringens | 分子名称: | 2-acetamido-2-deoxy-beta-D-galactopyranose, BETA-N-ACETYLGALACTOSAMINIDASE, FORMIC ACID | 著者 | Noach, I, Pluvinage, B, Laurie, C, Abe, K.T, Alteen, M, Vocadlo, D.J, Boraston, A.B. | 登録日 | 2015-12-10 | 公開日 | 2016-03-30 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | The Details of Glycolipid Glycan Hydrolysis by the Structural Analysis of a Family 123 Glycoside Hydrolase from Clostridium Perfringens J.Mol.Biol., 428, 2016
|
|
1A88
| CHLOROPEROXIDASE L | 分子名称: | CHLOROPEROXIDASE L | 著者 | Hofmann, B, Toelzer, S, Pelletier, I, Altenbuchner, J, Van Pee, K.-H, Hecht, H.-J. | 登録日 | 1998-04-03 | 公開日 | 1998-10-14 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural investigation of the cofactor-free chloroperoxidases. J.Mol.Biol., 279, 1998
|
|
5FU2
| The complexity of the Ruminococcus flavefaciens cellulosome reflects an expansion in glycan recognition | 分子名称: | CALCIUM ION, CBM74-RFGH5, SODIUM ION, ... | 著者 | Basle, A, Luis, A.S, Venditto, I, Gilbert, H.J. | 登録日 | 2016-01-20 | 公開日 | 2016-06-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Complexity of the Ruminococcus Flavefaciens Cellulosome Reflects an Expansion in Glycan Recognition. Proc.Natl.Acad.Sci.USA, 113, 2016
|
|
4I2V
| X-ray structure of the unliganded uridine phosphorylase from Yersinia pseudotuberculosis at 2.12A resolution | 分子名称: | Uridine phosphorylase | 著者 | Lashkov, A.A, Balaev, V.V, Prokofev, I.I, Betzel, C, Gabdoulkhakov, A.G, Mikhailov, A.M. | 登録日 | 2012-11-23 | 公開日 | 2013-12-18 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.121 Å) | 主引用文献 | X-ray structure of the unliganded uridine phosphorylase from Yersinia pseudotuberculosis at 2.12A resolution To be Published
|
|
1AE5
| HUMAN HEPARIN BINDING PROTEIN | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HEPARIN BINDING PROTEIN | 著者 | Iversen, L.F, Kastrup, J.S, Bjorn, S.E, Rasmussen, P.B, Wiberg, F.C, Flodgaard, H.J, Larsen, I.K. | 登録日 | 1997-03-05 | 公開日 | 1998-03-11 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of HBP, a multifunctional protein with a serine proteinase fold. Nat.Struct.Biol., 4, 1997
|
|
5JJN
| Structure of the SRII/HtrII(G83F) Complex in P212121 space group ("V" shape) | 分子名称: | EICOSANE, RETINAL, Sensory rhodopsin II transducer, ... | 著者 | Ishchenko, A, Round, E, Borshchevskiy, V, Grudinin, S, Gushchin, I, Klare, J, Remeeva, A, Polovinkin, V, Utrobin, P, Balandin, T, Engelhard, M, Bueldt, G, Gordeliy, V. | 登録日 | 2016-04-24 | 公開日 | 2017-02-15 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | New Insights on Signal Propagation by Sensory Rhodopsin II/Transducer Complex. Sci Rep, 7, 2017
|
|
8P9G
| Crystal structure of the first bromodomain of human BRD4 in complex with the dual BET/HDAC inhibitor NB390 | 分子名称: | 1,2-ETHANEDIOL, Bromodomain-containing protein 4, ~{N}-(2-aminophenyl)-4-[(~{E})-(6-methyl-7-oxidanyl-1~{H}-indol-4-yl)diazenyl]benzamide | 著者 | Balourdas, D.I, Bauer, N, Knapp, S, Joerger, A.C, Structural Genomics Consortium (SGC) | 登録日 | 2023-06-06 | 公開日 | 2023-07-05 | 最終更新日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | 主引用文献 | Development of Potent Dual BET/HDAC Inhibitors via Pharmacophore Merging and Structure-Guided Optimization. Acs Chem.Biol., 19, 2024
|
|
8P9H
| Crystal structure of the first bromodomain of human BRD4 in complex with the dual BET/HDAC inhibitor NB437 | 分子名称: | 1,2-ETHANEDIOL, Bromodomain-containing protein 4, ~{N}-(2-aminophenyl)-2-(6-methyl-7-oxidanylidene-1~{H}-pyrrolo[2,3-c]pyridin-4-yl)quinoline-6-carboxamide | 著者 | Balourdas, D.I, Bauer, N, Knapp, S, Joerger, A.C, Structural Genomics Consortium (SGC) | 登録日 | 2023-06-06 | 公開日 | 2023-07-05 | 最終更新日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | 主引用文献 | Development of Potent Dual BET/HDAC Inhibitors via Pharmacophore Merging and Structure-Guided Optimization. Acs Chem.Biol., 19, 2024
|
|
6Z2L
| |
1AMR
| X-RAY CRYSTALLOGRAPHIC STUDY OF PYRIDOXAMINE 5'-PHOSPHATE-TYPE ASPARTATE AMINOTRANSFERASES FROM ESCHERICHIA COLI IN THREE FORMS | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ASPARTATE AMINOTRANSFERASE, MALEIC ACID | 著者 | Miyahara, I, Hirotsu, K, Hayashi, H, Kagamiyama, H. | 登録日 | 1994-07-01 | 公開日 | 1994-09-30 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | X-ray crystallographic study of pyridoxamine 5'-phosphate-type aspartate aminotransferases from Escherichia coli in three forms. J.Biochem.(Tokyo), 116, 1994
|
|
8QQ7
| Structure of SpNOX: a Bacterial NADPH oxidase | 分子名称: | DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, FAD-binding FR-type domain-containing protein, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Thepaut, M, Petit-Hartlein, I, Vermot, A, Chaptal, V, Humm, A.S, Dupeux, F, Marquez, J.A, Smith, S, Fieschi, F. | 登録日 | 2023-10-04 | 公開日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (3.62 Å) | 主引用文献 | X-ray structure and enzymatic study of a bacterial NADPH oxidase highlight the activation mechanism of eukaryotic NOX. Elife, 13, 2024
|
|