1F5M
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![BU of 1f5m by Molmil](/molmil-images/mine/1f5m) | STRUCTURE OF THE GAF DOMAIN | Descriptor: | BROMIDE ION, GAF | Authors: | Ho, Y.S, Burden, L.M, Hurley, J.H. | Deposit date: | 2000-06-15 | Release date: | 2000-11-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the GAF domain, a ubiquitous signaling motif and a new class of cyclic GMP receptor. EMBO J., 19, 2000
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3PFQ
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![BU of 3pfq by Molmil](/molmil-images/mine/3pfq) | Crystal Structure and Allosteric Activation of Protein Kinase C beta II | Descriptor: | CALCIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Protein kinase C beta type, ... | Authors: | Leonard, T.A, Rozycki, B, Saidi, L.F, Hummer, G, Hurley, J.H. | Deposit date: | 2010-10-28 | Release date: | 2011-02-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Crystal Structure and Allosteric Activation of Protein Kinase C beta II Cell(Cambridge,Mass.), 144, 2011
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1P4U
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![BU of 1p4u by Molmil](/molmil-images/mine/1p4u) | CRYSTAL STRUCTURE OF GGA3 GAE DOMAIN IN COMPLEX WITH RABAPTIN-5 PEPTIDE | Descriptor: | ADP-ribosylation factor binding protein GGA3, Rabaptin-5 | Authors: | Miller, G.J, Mattera, R, Bonifacino, J.S, Hurley, J.H. | Deposit date: | 2003-04-24 | Release date: | 2003-07-29 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | RECOGNITION OF ACCESSORY PROTEIN MOTIFS BY THE GAMMA-ADAPTIN EAR DOMAIN OF GGA3 Nat.Struct.Biol., 10, 2003
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1LF8
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![BU of 1lf8 by Molmil](/molmil-images/mine/1lf8) | Complex of GGA3-VHS Domain and CI-MPR C-terminal Phosphopeptide | Descriptor: | ADP-ribosylation factor binding protein GGA3, Cation-independent mannose-6-phosphate receptor | Authors: | Kato, Y, Misra, S, Puertollano, R, Hurley, J.H, Bonifacino, J.S. | Deposit date: | 2002-04-10 | Release date: | 2002-06-26 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Phosphoregulation of sorting signal-VHS domain interactions by a direct electrostatic mechanism. Nat.Struct.Biol., 9, 2002
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1JPL
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![BU of 1jpl by Molmil](/molmil-images/mine/1jpl) | GGA3 VHS domain complexed with C-terminal peptide from cation-independent mannose 6-phosphate receptor | Descriptor: | ADP-RIBOSYLATION FACTOR BINDING PROTEIN GGA3, Cation-Independent Mannose 6-phosphate receptor | Authors: | Misra, S, Puertollano, R, Bonifacino, J.S, Hurley, J.H. | Deposit date: | 2001-08-02 | Release date: | 2002-02-27 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for acidic-cluster-dileucine sorting-signal recognition by VHS domains. Nature, 415, 2002
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1AB8
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![BU of 1ab8 by Molmil](/molmil-images/mine/1ab8) | |
1BO1
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![BU of 1bo1 by Molmil](/molmil-images/mine/1bo1) | PHOSPHATIDYLINOSITOL PHOSPHATE KINASE TYPE II BETA | Descriptor: | PROTEIN (PHOSPHATIDYLINOSITOL PHOSPHATE KINASE IIBETA) | Authors: | Rao, V.D, Misra, S, Boronenkov, I.V, Anderson, R.A, Hurley, J.H. | Deposit date: | 1998-08-02 | Release date: | 1998-10-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of type IIbeta phosphatidylinositol phosphate kinase: a protein kinase fold flattened for interfacial phosphorylation. Cell(Cambridge,Mass.), 94, 1998
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1ELK
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![BU of 1elk by Molmil](/molmil-images/mine/1elk) | VHS domain of TOM1 protein from H. sapiens | Descriptor: | TARGET OF MYB1 | Authors: | Misra, S, Beach, B, Hurley, J.H. | Deposit date: | 2000-03-13 | Release date: | 2000-03-22 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structure of the VHS domain of human Tom1 (target of myb 1): insights into interactions with proteins and membranes Biochemistry, 39, 2000
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1ZI7
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![BU of 1zi7 by Molmil](/molmil-images/mine/1zi7) | Structure of truncated yeast oxysterol binding protein Osh4 | Descriptor: | KES1 protein, SULFATE ION | Authors: | Im, Y.J, Raychaudhuri, S, Prinz, W.A, Hurley, J.H. | Deposit date: | 2005-04-27 | Release date: | 2005-09-06 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural mechanism for sterol sensing and transport by OSBP-related proteins Nature, 437, 2005
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1XA6
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![BU of 1xa6 by Molmil](/molmil-images/mine/1xa6) | Crystal Structure of the Human Beta2-Chimaerin | Descriptor: | Beta2-chimaerin, ZINC ION | Authors: | Canagarajah, B, Leskow, F.C, Ho, J.Y, Mischak, H, Saidi, L.F, Kazanietz, M.G, Hurley, J.H. | Deposit date: | 2004-08-25 | Release date: | 2004-11-23 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural mechanism for lipid activation of the Rac-specific GAP, beta2-chimaerin. Cell(Cambridge,Mass.), 119, 2004
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1ZB1
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![BU of 1zb1 by Molmil](/molmil-images/mine/1zb1) | Structure basis for endosomal targeting by the Bro1 domain | Descriptor: | BRO1 protein | Authors: | Kim, J, Sitaraman, S, Hierro, A, Beach, B.M, Odorizzi, G, Hurley, J.H. | Deposit date: | 2005-04-07 | Release date: | 2005-06-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis for endosomal targeting by the Bro1 domain. Dev.Cell, 8, 2005
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2OJQ
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![BU of 2ojq by Molmil](/molmil-images/mine/2ojq) | Crystal structure of Alix V domain | Descriptor: | Programmed cell death 6-interacting protein | Authors: | Lee, S, Hurley, J.H. | Deposit date: | 2007-01-13 | Release date: | 2007-02-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.87 Å) | Cite: | Structural basis for viral late-domain binding to Alix Nat.Struct.Mol.Biol., 14, 2007
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1Z2P
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![BU of 1z2p by Molmil](/molmil-images/mine/1z2p) | Inositol 1,3,4-trisphosphate 5/6-Kinase in complex with Mg2+/AMP-PCP/Ins(1,3,4)P3 | Descriptor: | (1S,3S,4S)-1,3,4-TRIPHOSPHO-MYO-INOSITOL, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... | Authors: | Miller, G.J, Wilson, M.P, Majerus, P.W, Hurley, J.H. | Deposit date: | 2005-03-08 | Release date: | 2005-04-19 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.22 Å) | Cite: | Specificity determinants in inositol polyphosphate synthesis: crystal structure of inositol 1,3,4-trisphosphate 5/6-kinase. Mol.Cell, 18, 2005
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1Z2N
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![BU of 1z2n by Molmil](/molmil-images/mine/1z2n) | Inositol 1,3,4-trisphosphate 5/6-kinase complexed Mg2+/ADP | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, inositol 1,3,4-trisphosphate 5/6-kinase | Authors: | Miller, G.J, Wilson, M.P, Majerus, P.W, Hurley, J.H. | Deposit date: | 2005-03-08 | Release date: | 2005-04-19 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Specificity determinants in inositol polyphosphate synthesis: crystal structure of inositol 1,3,4-trisphosphate 5/6-kinase. Mol.Cell, 18, 2005
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1Z2O
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![BU of 1z2o by Molmil](/molmil-images/mine/1z2o) | Inositol 1,3,4-trisphosphate 5/6-Kinase in complex with mg2+/ADP/Ins(1,3,4,6)P4 | Descriptor: | (1S,3R,4R,6S)-1,3,4,6-TETRAPKISPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Miller, G.J, Wilson, M.P, Majerus, P.W, Hurley, J.H. | Deposit date: | 2005-03-08 | Release date: | 2005-04-19 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.24 Å) | Cite: | Specificity determinants in inositol polyphosphate synthesis: crystal structure of inositol 1,3,4-trisphosphate 5/6-kinase. Mol.Cell, 18, 2005
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1MLV
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![BU of 1mlv by Molmil](/molmil-images/mine/1mlv) | Structure and Catalytic Mechanism of a SET Domain Protein Methyltransferase | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Ribulose-1,5 biphosphate carboxylase/oxygenase large subunit N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | Authors: | Trievel, R.C, Beach, B.M, Dirk, L.M.A, Houtz, R.L, Hurley, J.H. | Deposit date: | 2002-08-30 | Release date: | 2002-10-30 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure and catalytic mechanism of a SET domain protein methyltransferase. Cell(Cambridge,Mass.), 111, 2002
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1XHB
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![BU of 1xhb by Molmil](/molmil-images/mine/1xhb) | The Crystal Structure of UDP-GalNAc: polypeptide alpha-N-acetylgalactosaminyltransferase-T1 | Descriptor: | CALCIUM ION, MANGANESE (II) ION, Polypeptide N-acetylgalactosaminyltransferase 1, ... | Authors: | Fritz, T.A, Hurley, J.H, Trinh, L.B, Shiloach, J, Tabak, L.A. | Deposit date: | 2004-09-17 | Release date: | 2004-10-26 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The beginnings of mucin biosynthesis: The crystal structure of UDP-GalNAc:polypeptide {alpha}-N-acetylgalactosaminyltransferase-T1 Proc.Natl.Acad.Sci.USA, 101, 2004
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1YD8
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![BU of 1yd8 by Molmil](/molmil-images/mine/1yd8) | COMPLEX OF HUMAN GGA3 GAT DOMAIN AND UBIQUITIN | Descriptor: | ADP-RIBOSYLATION FACTOR BINDING PROTEIN GGA3, UBIQUIN | Authors: | Prag, G, Lee, S, Mattera, R, Arighi, C.N, Beach, B.M, Bonifacino, J.S, Hurley, J.H. | Deposit date: | 2004-12-23 | Release date: | 2005-02-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural mechanism for ubiquitinated-cargo recognition by the Golgi-localized, {gamma}-ear-containing, ADP-ribosylation-factor-binding proteins Proc.Natl.Acad.Sci.USA, 102, 2005
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1ZHZ
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![BU of 1zhz by Molmil](/molmil-images/mine/1zhz) | Structure of yeast oxysterol binding protein Osh4 in complex with ergosterol | Descriptor: | ERGOSTEROL, KES1 protein, LEAD (II) ION | Authors: | Im, Y.J, Raychaudhuri, S, Prinz, W.A, Hurley, J.H. | Deposit date: | 2005-04-26 | Release date: | 2005-09-06 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural mechanism for sterol sensing and transport by OSBP-related proteins Nature, 437, 2005
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1ZHY
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![BU of 1zhy by Molmil](/molmil-images/mine/1zhy) | Structure of yeast oxysterol binding protein Osh4 in complex with cholesterol | Descriptor: | CHOLESTEROL, KES1 protein, LEAD (II) ION | Authors: | Im, Y.J, Raychaudhuri, S, Prinz, W.A, Hurley, J.H. | Deposit date: | 2005-04-26 | Release date: | 2005-09-06 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural mechanism for sterol sensing and transport by OSBP-related proteins Nature, 437, 2005
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1ZHW
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![BU of 1zhw by Molmil](/molmil-images/mine/1zhw) | Structure of yeast oxysterol binding protein Osh4 in complex with 20-hydroxycholesterol | Descriptor: | 20-HYDROXYCHOLESTEROL, KES1 protein, LEAD (II) ION | Authors: | Im, Y.J, Raychaudhuri, S, Prinz, W.A, Hurley, J.H. | Deposit date: | 2005-04-26 | Release date: | 2005-09-06 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural mechanism for sterol sensing and transport by OSBP-related proteins Nature, 437, 2005
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1ZHX
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![BU of 1zhx by Molmil](/molmil-images/mine/1zhx) | Structure of yeast oxysterol binding protein Osh4 in complex with 25-hydroxycholesterol | Descriptor: | 25-HYDROXYCHOLESTEROL, KES1 protein | Authors: | Im, Y.J, Raychaudhuri, S, Prinz, W.A, Hurley, J.H. | Deposit date: | 2005-04-26 | Release date: | 2005-09-06 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural mechanism for sterol sensing and transport by OSBP-related proteins Nature, 437, 2005
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1OZV
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![BU of 1ozv by Molmil](/molmil-images/mine/1ozv) | Crystal structure of the SET domain of LSMT bound to Lysine and AdoHcy | Descriptor: | LYSINE, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast, ... | Authors: | Trievel, R.C, Flynn, E.M, Houtz, R.L, Hurley, J.H. | Deposit date: | 2003-04-09 | Release date: | 2003-07-01 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Mechanism of multiple lysine methylation by the SET domain enzyme Rubisco LSMT Nat.Struct.Biol., 10, 2003
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1ZHT
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![BU of 1zht by Molmil](/molmil-images/mine/1zht) | Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol | Descriptor: | 7-HYDROXYCHOLESTEROL, KES1 protein | Authors: | Im, Y.J, Raychaudhuri, S, Prinz, W.A, Hurley, J.H. | Deposit date: | 2005-04-26 | Release date: | 2005-09-06 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural mechanism for sterol sensing and transport by OSBP-related proteins Nature, 437, 2005
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1P0Y
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![BU of 1p0y by Molmil](/molmil-images/mine/1p0y) | Crystal structure of the SET domain of LSMT bound to MeLysine and AdoHcy | Descriptor: | N-METHYL-LYSINE, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast, ... | Authors: | Trievel, R.C, Flynn, E.M, Houtz, R.L, Hurley, J.H. | Deposit date: | 2003-04-11 | Release date: | 2003-07-01 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Mechanism of multiple lysine methylation by the SET domain enzyme Rubisco LSMT Nat.Struct.Biol., 10, 2003
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