8C1V
| SARS-CoV-2 S-trimer (3 RBDs up) bound to TriSb92, fitted into cryo-EM map | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Sb92, ... | Authors: | Huiskonen, J.T, Rissanen, I, Hannula, L. | Deposit date: | 2022-12-21 | Release date: | 2023-04-19 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Intranasal trimeric sherpabody inhibits SARS-CoV-2 including recent immunoevasive Omicron subvariants. Nat Commun, 14, 2023
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5OXE
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6ZJM
| Atomic model of Andes virus glycoprotein spike tetramer generated by fitting into a Tula virus reconstruction | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein,Envelope polyprotein,Envelope polyprotein,Envelope polyprotein,Envelope polyprotein,Envelope polyprotein,Envelope polyprotein,Envelope polyprotein,Envelope polyprotein, ... | Authors: | Stass, R, Huiskonen, J.T, Rey, F, Guardado-Calvo, P. | Deposit date: | 2020-06-29 | Release date: | 2020-10-14 | Last modified: | 2020-10-28 | Method: | ELECTRON MICROSCOPY (11.4 Å) | Cite: | The Hantavirus Surface Glycoprotein Lattice and Its Fusion Control Mechanism. Cell, 183, 2020
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1GW8
| quasi-atomic resolution model of bacteriophage PRD1 sus607 mutant, obtained by combined cryo-EM and X-ray crystallography. | Descriptor: | MAJOR CAPSID PROTEIN | Authors: | San Martin, C, Huiskonen, J, Bamford, J.K.H, Butcher, S.J, Fuller, S.D, Bamford, D.H, Burnett, R.M. | Deposit date: | 2002-03-08 | Release date: | 2002-03-15 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (13.3 Å) | Cite: | Minor Proteins, Mobile Arms and Membrane-Capsid Interactions in the Bacteriophage Prd1 Capsid. Nat.Struct.Biol., 9, 2002
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5G47
| Structure of Gc glycoprotein from severe fever with thrombocytopenia syndrome virus in the trimeric postfusion conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, SFTSV GC | Authors: | Halldorsson, S, Behrens, A.J, Harlos, K, Huiskonen, J.T, Elliott, R.M, Crispin, M, Brennan, B, Bowden, T.A. | Deposit date: | 2016-05-05 | Release date: | 2016-07-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structure of a Phleboviral Envelope Glycoprotein Reveals a Consolidated Model of Membrane Fusion. Proc.Natl.Acad.Sci.USA, 113, 2016
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8BI4
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1GW7
| QUASI-ATOMIC RESOLUTION MODEL OF BACTERIOPHAGE PRD1 CAPSID, OBTAINED BY COMBINED CRYO-EM AND X-RAY CRYSTALLOGRAPHY. | Descriptor: | MAJOR CAPSID PROTEIN | Authors: | San Martin, C, Huiskonen, J, Bamford, J.K.H, Butcher, S.J, Fuller, S.D, Bamford, D.H, Burnett, R.M. | Deposit date: | 2002-03-08 | Release date: | 2002-03-13 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (13.5 Å) | Cite: | Minor Proteins, Mobile Arms, and Membrane-Capsid Interactions in Bacteriophage Prd1 Capsid Assembly Nat.Struct.Biol., 9, 2002
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7Q8S
| Leishmania major ADP-actin filament decorated with Leishmania major cofilin | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADF/Cofilin, Actin, ... | Authors: | Kotila, T, Muniyandi, S, Lappalainen, P, Huiskonen, J.T. | Deposit date: | 2021-11-11 | Release date: | 2022-05-18 | Last modified: | 2022-06-29 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite. Nat Commun, 13, 2022
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7B0A
| Puumala virus-like particle glycoprotein spike and lattice contacts model. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein, ... | Authors: | Rissanen, I, Stass, R, Huiskonen, J.T, Bowden, T.A. | Deposit date: | 2020-11-19 | Release date: | 2020-12-16 | Last modified: | 2021-01-13 | Method: | ELECTRON MICROSCOPY (13.9 Å) | Cite: | Molecular rationale for antibody-mediated targeting of the hantavirus fusion glycoprotein. Elife, 9, 2020
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7B09
| Puumala virus glycoprotein (Gc) in complex with fab fragment P-4G2. | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein, ... | Authors: | Rissanen, I, Stass, R, Huiskonen, J.T, Bowden, T.A. | Deposit date: | 2020-11-19 | Release date: | 2020-12-16 | Last modified: | 2021-01-13 | Method: | ELECTRON MICROSCOPY (13.4 Å) | Cite: | Molecular rationale for antibody-mediated targeting of the hantavirus fusion glycoprotein. Elife, 9, 2020
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7Q8B
| Leishmania major actin filament in ADP-Pi state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, MAGNESIUM ION, ... | Authors: | Kotila, T, Muniyandi, S, Lappalainen, P, Huiskonen, J.T. | Deposit date: | 2021-11-11 | Release date: | 2022-05-18 | Last modified: | 2022-06-29 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite. Nat Commun, 13, 2022
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7Q8C
| Leishmania major actin filament in ADP-state | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin, MAGNESIUM ION | Authors: | Kotila, T, Muniyandi, S, Lappalainen, P, Huiskonen, J.T. | Deposit date: | 2021-11-11 | Release date: | 2022-05-18 | Last modified: | 2022-06-29 | Method: | ELECTRON MICROSCOPY (2.72 Å) | Cite: | Structural basis of rapid actin dynamics in the evolutionarily divergent Leishmania parasite. Nat Commun, 13, 2022
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8P0V
| Structure of the human Commander complex coiled coils, DENND10 and partial Retriever subcomplex | Descriptor: | Coiled-coil domain-containing protein 22, Coiled-coil domain-containing protein 93, DENN domain-containing protein 10, ... | Authors: | Kumpula, E.P, Laulumaa, S, Huiskonen, J.T. | Deposit date: | 2023-05-10 | Release date: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | Structure and interactions of the endogenous human Commander complex. Nat.Struct.Mol.Biol., 2024
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8BF9
| Molecular view of ER membrane remodeling by the Sec61/TRAP translocon. | Descriptor: | 60S ribosomal protein L39, Large ribosomal subunit protein eL31, Large ribosomal subunit protein eL38, ... | Authors: | Karki, S, Javanainen, M, Tranter, D, Rehan, S, Huiskonen, J, Happonen, L, Paavilainen, V. | Deposit date: | 2022-10-24 | Release date: | 2023-11-01 | Last modified: | 2023-12-20 | Method: | ELECTRON MICROSCOPY (2.69 Å) | Cite: | Molecular view of ER membrane remodeling by the Sec61/TRAP translocon. Embo Rep., 24, 2023
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8P0W
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8P0X
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5ACA
| Structure-based energetics of protein interfaces guide Foot-and-Mouth disease virus vaccine design | Descriptor: | VP1, VP2, VP3, ... | Authors: | Kotecha, A, Seago, J, Scott, K, Burman, A, Loureiro, S, Ren, J, Porta, C, Ginn, H.M, Jackson, T, Perez-Martin, E, Siebert, C.A, Paul, G, Huiskonen, J.T, Jones, I.M, Esnouf, R.M, Fry, E.E, Maree, F.F, Charleston, B, Stuart, D.I. | Deposit date: | 2015-08-14 | Release date: | 2015-09-23 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure-Based Energetics of Protein Interfaces Guide Foot-and-Mouth Disease Vaccine Design Nat.Struct.Mol.Biol., 22, 2015
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5AC9
| Structure-based energetics of protein interfaces guide Foot-and-Mouth disease virus vaccine design | Descriptor: | VP1, VP2, VP3, ... | Authors: | Kotecha, A, Seago, J, Scott, K, Burman, A, Loureiro, S, Ren, J, Porta, C, Ginn, H.M, Jackson, T, PerezMartin, E, Siebert, C.A, Paul, G, Huiskonen, J.T, Jones, I.M, Esnouf, R.M, Fry, E.E, Maree, F.F, Charleston, B, Stuart, D.I. | Deposit date: | 2015-08-14 | Release date: | 2015-09-23 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure-Based Energetics of Protein Interfaces Guide Foot-and-Mouth Disease Vaccine Design Nat.Struct.Mol.Biol., 22, 2015
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5MUV
| Atomic structure fitted into a localized reconstruction of bacteriophage phi6 packaging hexamer P4 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Packaging enzyme P4 | Authors: | Sun, Z, El Omari, K, Sun, X, Ilca, S, Kotecha, A, Stuart, D.I, Poranen, M.M, Huiskonen, J.T. | Deposit date: | 2017-01-14 | Release date: | 2017-03-22 | Last modified: | 2019-04-24 | Method: | ELECTRON MICROSCOPY (9.1 Å) | Cite: | Double-stranded RNA virus outer shell assembly by bona fide domain-swapping. Nat Commun, 8, 2017
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5MUW
| Atomic structure of P4 packaging enzyme fitted into a localized reconstruction of bacteriophage phi6 vertex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Packaging enzyme P4 | Authors: | Sun, Z, El Omari, K, Sun, X, Ilca, S, Kotecha, A, Stuart, D.I, Poranen, M.M, Huiskonen, J.T. | Deposit date: | 2017-01-14 | Release date: | 2017-03-22 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Double-stranded RNA virus outer shell assembly by bona fide domain-swapping. Nat Commun, 8, 2017
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6Z06
| Crystal structure of Puumala virus Gc in complex with Fab 4G2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope polyprotein, Fab 4G2 Heavy chain, ... | Authors: | Rissanen, I.R, Stass, R, Krumm, S.A, Seow, J, Hulswit, R.J.G, Paesen, G.C, Hepojoki, J, Vapalahti, O, Lundkvist, A, Reynard, O, Volchkov, V, Doores, K.J, Huiskonen, J.T, Bowden, T.A. | Deposit date: | 2020-05-07 | Release date: | 2020-12-30 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (3.5 Å) | Cite: | Molecular rationale for antibody-mediated targeting of the hantavirus fusion glycoprotein. Elife, 9, 2020
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8A06
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5K47
| CryoEM structure of the human Polycystin-2/PKD2 TRP channel | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Polycystin-2 | Authors: | Pike, A.C.W, Grieben, M, Shintre, C.A, Tessitore, A, Shrestha, L, Mukhopadhyay, S, Mahajan, P, Chalk, R, Burgess-Brown, N.A, Huiskonen, J.T, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Carpenter, E.P, Structural Genomics Consortium (SGC) | Deposit date: | 2016-05-20 | Release date: | 2016-08-24 | Last modified: | 2020-10-21 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2). Nat. Struct. Mol. Biol., 24, 2017
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6HY0
| Atomic models of P1, P4 C-terminal fragment and P8 fitted in the bacteriophage phi6 nucleocapsid reconstructed with icosahedral symmetry | Descriptor: | Major Outer Capsid Protein P8, Major inner protein P1, Packaging Enzyme P4 | Authors: | El Omari, K, Ilca, S.L, Stuart, D.I, Huiskonen, J.T. | Deposit date: | 2018-10-18 | Release date: | 2019-06-12 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Multiple liquid crystalline geometries of highly compacted nucleic acid in a dsRNA virus. Nature, 570, 2019
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1YQ5
| PRD1 vertex protein P5 | Descriptor: | Minor capsid protein | Authors: | Merckel, M.C, Huiskonen, J.T, Goldman, A, Bamford, D.H, Tuma, R. | Deposit date: | 2005-02-01 | Release date: | 2005-04-26 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structure of the bacteriophage PRD1 spike sheds light on the evolution of viral capsid architecture. Mol.Cell, 18, 2005
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