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PDB: 43 件

4U6U
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Crystal Structure of the Cog5-Cog7 complex from Kluyveromyces lactis
分子名称: Cog5, Cog7
著者Ha, J.Y, Jeffrey, P.D, Hughson, F.M.
登録日2014-07-29
公開日2014-10-22
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Cog5-Cog7 crystal structure reveals interactions essential for the function of a multisubunit tethering complex.
Proc.Natl.Acad.Sci.USA, 111, 2014
8CUK
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X-ray Structure of the WD40 domain of HOPS subunit Vps11 from Yeast
分子名称: E3 ubiquitin-protein ligase PEP5
著者Port, S.A, Baker, R.W, Jeffrey, P.D, Hughson, F.M.
登録日2022-05-17
公開日2022-05-25
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献X-ray Structure of the WD40 domain of HOPS subunit Vps11 from Yeast
to be published
2HJE
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Crystal structure of Vibrio harveyi LuxQ periplasmic domain
分子名称: Autoinducer 2 sensor kinase/phosphatase luxQ, NICKEL (II) ION
著者Neiditch, M.B, Kelly, R.C, Hughson, F.M.
登録日2006-06-30
公開日2006-09-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Ligand-induced asymmetry in histidine sensor kinase complex regulates quorum sensing.
Cell(Cambridge,Mass.), 126, 2006
1ZHH
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Crystal Structure of the Apo Form of Vibrio Harveyi LUXP Complexed with the Periplasmic Domain of LUXQ
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Autoinducer 2 sensor kinase/phosphatase luxQ, Autoinducer 2-binding periplasmic protein luxP
著者Neiditch, M.B, Federle, M.J, Miller, S.T, Bassler, B.L, Hughson, F.M.
登録日2005-04-25
公開日2005-05-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Regulation of LuxPQ Receptor Activity by the Quorum-Sensing Signal Autoinducer-2.
Mol.Cell, 18, 2005
1HTM
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STRUCTURE OF INFLUENZA HAEMAGGLUTININ AT THE PH OF MEMBRANE FUSION
分子名称: HEMAGGLUTININ HA1 CHAIN, HEMAGGLUTININ HA2 CHAIN
著者Bullough, P.A, Hughson, F.M, Skehel, J.J, Wiley, D.C.
登録日1994-11-02
公開日1995-02-14
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of influenza haemagglutinin at the pH of membrane fusion.
Nature, 371, 1994
8FTU
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Crystal structure of the SNARE Use1 bound to Dsl1 complex subunits Sec39 and Dsl1, Revised Use1 structure
分子名称: Protein transport protein DSL1, Protein transport protein SEC39, Vesicle transport protein USE1
著者Travis, S.M, Jeffrey, P.D, Hughson, F.M.
登録日2023-01-13
公開日2023-03-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (5.73 Å)
主引用文献Structure of a membrane tethering complex incorporating multiple SNAREs.
Nat.Struct.Mol.Biol., 31, 2024
5BV0
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Crystal Structure of a Complex Between the SNARE Nyv1 and the HOPS Vps33-Vps16 subcomplex from Chaetomium thermophilum
分子名称: SM (Sec1/Munc18-like) protein, SNARE domain, Vps16
著者Baker, R.W, Jeffrey, P.D, Hughson, F.M.
登録日2015-06-04
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A direct role for the Sec1/Munc18-family protein Vps33 as a template for SNARE assembly.
Science, 349, 2015
5BUZ
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Crystal Structure of a Complex Between the SNARE Vam3 and the HOPS Vps33-Vps16 subcomplex from Chaetomium thermophilum
分子名称: Putative vacuolar protein sorting-associated protein, SM (Sec1/Munc18-like) protein, SNAP receptor-like protein
著者Baker, R.W, Jeffrey, P.D, Hughson, F.M.
登録日2015-06-04
公開日2015-08-05
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献A direct role for the Sec1/Munc18-family protein Vps33 as a template for SNARE assembly.
Science, 349, 2015
5BV1
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Crystal Structure of a Vps33-Vps16 Complex from Chaetomium thermophilum
分子名称: D-MALATE, Putative vacuolar protein sorting-associated protein, VPS33
著者Baker, R.W, Jeffrey, P.D, Hughson, F.M.
登録日2015-06-04
公開日2015-08-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.902 Å)
主引用文献A direct role for the Sec1/Munc18-family protein Vps33 as a template for SNARE assembly.
Science, 349, 2015
8DIT
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Cryo-EM structure of a HOPS core complex containing Vps33, Vps16, and Vps18
分子名称: Vacuolar protein sorting-associated protein 16, Vacuolar protein sorting-associated protein 18, Vacuolar protein sorting-associated protein 33
著者Port, S.A, Farrell, P.D, Jeffrey, P.D, DiMaio, F, Hughson, F.M.
登録日2022-06-29
公開日2022-08-31
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (5.1 Å)
主引用文献Cryo-EM structure of the HOPS core complex and its implication for SNARE assembly
To Be Published
8EKI
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CryoEM structure of the Dsl1 complex bound to SNAREs Sec20 and Use1
分子名称: Protein transport protein DSL1, Protein transport protein SEC20, Protein transport protein SEC39, ...
著者DAmico, K.A, Jeffrey, P.D, Hughson, F.M.
登録日2022-09-21
公開日2023-10-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structure of a membrane tethering complex incorporating multiple SNAREs.
Nat.Struct.Mol.Biol., 31, 2024
1EZ3
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CRYSTAL STRUCTURE OF THE NEURONAL T-SNARE SYNTAXIN-1A
分子名称: SYNTAXIN-1A
著者Lerman, J.C, Robblee, J, Fairman, R, Hughson, F.M.
登録日2000-05-09
公開日2000-06-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural analysis of the neuronal SNARE protein syntaxin-1A.
Biochemistry, 39, 2000
1FIO
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CRYSTAL STRUCTURE OF YEAST T-SNARE PROTEIN SSO1
分子名称: SSO1 PROTEIN, ZINC ION
著者Munson, M, Chen, X, Cocina, A.E, Schultz, S.M, Hughson, F.M.
登録日2000-08-04
公開日2000-10-11
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Interactions within the yeast t-SNARE Sso1p that control SNARE complex assembly.
Nat.Struct.Biol., 7, 2000
6U3W
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Crystal structure of yeast alpha/epsilon-COP of the COPI vesicular coat
分子名称: Coatomer subunit alpha, Coatomer subunit epsilon, GLYCEROL
著者Travis, S.M, Hughson, F.M.
登録日2019-08-22
公開日2019-11-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.394 Å)
主引用文献Roles of singleton tryptophan motifs in COPI coat stability and vesicle tethering.
Proc.Natl.Acad.Sci.USA, 116, 2019
6U3V
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Crystal structure of human alpha/epsilon-COP of the COPI vesicular coat bound to alpha-COP STM1
分子名称: Coatomer subunit alpha, Coatomer subunit epsilon
著者Travis, S.M, Hughson, F.M.
登録日2019-08-22
公開日2019-11-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.96 Å)
主引用文献Roles of singleton tryptophan motifs in COPI coat stability and vesicle tethering.
Proc.Natl.Acad.Sci.USA, 116, 2019
6TZT
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BU of 6tzt by Molmil
Crystal structure of human alpha/epsilon-COP of the COPI vesicular coat bound to alpha-COP STM2
分子名称: Coatomer subunit alpha, Coatomer subunit epsilon
著者Travis, S.M, Hughson, F.M.
登録日2019-08-13
公開日2019-11-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.065 Å)
主引用文献Roles of singleton tryptophan motifs in COPI coat stability and vesicle tethering.
Proc.Natl.Acad.Sci.USA, 116, 2019
6WC3
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Crystal structure of the SNARE Sec20 bound to Dsl1 complex subunit Tip20
分子名称: Protein transport protein SEC20, Protein transport protein TIP20
著者Travis, S.M, Jeffrey, P.D, Hughson, F.M.
登録日2020-03-29
公開日2020-05-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.203 Å)
主引用文献Structural basis for the binding of SNAREs to the multisubunit tethering complex Dsl1.
J.Biol.Chem., 295, 2020
6XJL
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BU of 6xjl by Molmil
Structure of the SM protein Vps45
分子名称: Vps45
著者Jeffrey, P.D, Shimamura, G.S, Allen, F, Hughson, F.M.
登録日2020-06-24
公開日2020-08-19
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Sec1/Munc18 protein Vps45 holds the Qa-SNARE Tlg2 in an open conformation.
Elife, 9, 2020
6XM1
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SM Protein Vps45 in Complex with Qa SNARE Tlg2
分子名称: Tlg2 Qa SNARE, Vps45
著者Jeffrey, P.D, Eisemann, T.J, Hughson, F.M.
登録日2020-06-29
公開日2020-08-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Sec1/Munc18 protein Vps45 holds the Qa-SNARE Tlg2 in an open conformation.
Elife, 9, 2020
6XMD
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SM Protein Vps45 in Complex with Qa SNARE Tlg2 (1-310)
分子名称: Tlg2 Qa SNARE, Vps45
著者Jeffrey, P.D, Eisemann, T.J, Hughson, F.M.
登録日2020-06-30
公開日2020-08-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献The Sec1/Munc18 protein Vps45 holds the Qa-SNARE Tlg2 in an open conformation.
Elife, 9, 2020
3K8P
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Structural basis for vesicle tethering by the Dsl1 complex
分子名称: Dsl1, Protein transport protein SEC39
著者Ren, Y, Jeffrey, P.D, Hughson, F.M.
登録日2009-10-14
公開日2009-11-10
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A structure-based mechanism for vesicle capture by the multisubunit tethering complex Dsl1.
Cell(Cambridge,Mass.), 139, 2009
3KKI
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PLP-Dependent Acyl-CoA transferase CqsA
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CAI-1 autoinducer synthase, MAGNESIUM ION, ...
著者Kelly, R.C, Jeffrey, P.D, Hughson, F.M.
登録日2009-11-05
公開日2009-11-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Vibrio cholerae quorum-sensing autoinducer CAI-1: analysis of the biosynthetic enzyme CqsA.
Nat.Chem.Biol., 5, 2009
1TM2
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Crystal Structure of the apo form of the Salmonella typhimurium AI-2 receptor LsrB
分子名称: sugar transport protein
著者Miller, S.T, Xavier, K.B, Campagna, S.R, Taga, M.E, Semmelhack, M.F, Bassler, B.L, Hughson, F.M.
登録日2004-06-10
公開日2004-09-28
最終更新日2018-01-31
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Salmonella typhimurium Recognizes a Chemically Distinct Form of the Bacterial Quorum-Sensing Signal AI-2
Mol.Cell, 15, 2004
1TJY
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Crystal Structure of Salmonella typhimurium AI-2 receptor LsrB in complex with R-THMF
分子名称: (2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran, sugar transport protein
著者Miller, S.T, Xavier, K.B, Campagna, S.R, Taga, M.E, Semmelhack, M.F, Bassler, B.L, Hughson, F.M.
登録日2004-06-07
公開日2004-09-28
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Salmonella typhimurium Recognizes a Chemically Distinct Form of the Bacterial Quorum-Sensing Signal AI-2
Mol.Cell, 15, 2004
4H5J
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Crystal Structure of the Guanine Nucleotide Exchange Factor Sec12 (P64 form)
分子名称: Guanine nucleotide-exchange factor SEC12, POTASSIUM ION
著者McMahon, C, Jeffrey, P.D, Hughson, F.M.
登録日2012-09-18
公開日2012-11-07
最終更新日2013-01-09
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献The structure of sec12 implicates potassium ion coordination in sar1 activation.
J.Biol.Chem., 287, 2012

 

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