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PDB: 153 件

5TET
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BU of 5tet by Molmil
TEV Cleaved Human ATP Citrate Lyase Bound to 4S Hydroxycitrate
分子名称: 3-C-carboxy-2-deoxy-D-erythro-pentaric acid, ATP-citrate synthase, GLYCEROL, ...
著者Hu, J, Fraser, M.E.
登録日2016-09-22
公開日2017-08-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TDZ
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BU of 5tdz by Molmil
TEV Cleaved Human ATP Citrate Lyase Bound to Tartrate and ADP
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE, ADENOSINE-5'-DIPHOSPHATE, ...
著者Hu, J, Fraser, M.E.
登録日2016-09-20
公開日2017-08-09
最終更新日2017-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TES
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BU of 5tes by Molmil
TEV Cleaved Human ATP Citrate Lyase Bound to Citrate and ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, CITRATE ANION, ...
著者Hu, J, Fraser, M.E.
登録日2016-09-22
公開日2017-08-09
最終更新日2017-08-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TDF
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BU of 5tdf by Molmil
TEV Cleaved Human ATP Citrate Lyase Bound to 4S hydroxycitrate
分子名称: 3-C-carboxy-2-deoxy-D-erythro-pentaric acid, ADENINE, ADENOSINE-5'-DIPHOSPHATE, ...
著者Hu, J, Fraser, M.E.
登録日2016-09-19
公開日2017-08-09
最終更新日2017-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
3S0X
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BU of 3s0x by Molmil
The crystal structure of GxGD membrane protease FlaK
分子名称: Peptidase A24B, FlaK domain protein
著者Hu, J, Xue, Y, Ha, Y.
登録日2011-05-13
公開日2011-08-03
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献The crystal structure of GXGD membrane protease FlaK.
Nature, 475, 2011
2HDV
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BU of 2hdv by Molmil
Crystal structure of the Src Homology-2 domain of the adapter protein SH2-B
分子名称: SH2-B PH domain containing signaling mediator 1 gamma isoform
著者Hu, J, Hubbard, S.R.
登録日2006-06-20
公開日2006-08-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Basis for Phosphotyrosine Recognition by the Src Homology-2 Domains of the Adapter Proteins SH2-B and APS.
J.Mol.Biol., 361, 2006
2HDX
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BU of 2hdx by Molmil
Crystal structure of the Src homology-2 domain of SH2-B in complex with Jak2 pTyr813 phosphopeptide
分子名称: Jak2 protein, SH2-B PH domain containing signaling mediator 1 gamma isoform
著者Hu, J, Hubbard, S.R.
登録日2006-06-21
公開日2006-08-08
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural Basis for Phosphotyrosine Recognition by the Src Homology-2 Domains of the Adapter Proteins SH2-B and APS.
J.Mol.Biol., 361, 2006
2H95
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BU of 2h95 by Molmil
Structure of the Amantadine-Blocked Influenza A M2 Proton Channel Trans-membrane Domain by Solid-state NMR spectroscopy
分子名称: Matrix protein 2
著者Hu, J, Asbury, T, Cross, T.A.
登録日2006-06-08
公開日2007-04-24
最終更新日2024-05-29
実験手法SOLID-STATE NMR
主引用文献Backbone structure of the amantadine-blocked trans-membrane domain m2 proton channel from influenza a virus.
Biophys.J., 92, 2007
7X4B
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BU of 7x4b by Molmil
Crystal Structure of An Anti-CRISPR Protein
分子名称: Anti-CRISPR protein (AcrIIC1), SULFATE ION
著者Hu, J, Zhang, S, Gao, J.Y, Liu, X, Liu, J.
登録日2022-03-02
公開日2022-10-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献A redox switch regulates the assembly and anti-CRISPR activity of AcrIIC1.
Nat Commun, 13, 2022
5YDU
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BU of 5ydu by Molmil
Crystal structure of Utp30
分子名称: PHOSPHATE ION, Ribosome biogenesis protein UTP30
著者Hu, J, Zhu, X, Ye, K.
登録日2017-09-14
公開日2017-11-01
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.646 Å)
主引用文献Structure and RNA recognition of ribosome assembly factor Utp30.
RNA, 23, 2017
6DWB
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BU of 6dwb by Molmil
Structure of the Salmonella SPI-1 type III secretion injectisome needle filament
分子名称: Protein PrgI
著者Hu, J, Hong, C, Worrall, L.J, Vuckovic, M, Yu, Z, Strynadka, N.C.J.
登録日2018-06-26
公開日2018-10-03
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin.
Nat Commun, 9, 2018
6DV3
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BU of 6dv3 by Molmil
Structure of the Salmonella SPI-1 type III secretion injectisome secretin InvG in the open gate state
分子名称: Protein InvG
著者Hu, J, Worrall, L.J, Vuckovic, M, Atkinson, C.E, Strynadka, N.C.J.
登録日2018-06-22
公開日2018-10-03
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin.
Nat Commun, 9, 2018
5TE1
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BU of 5te1 by Molmil
C20S, C293G Mutant N-terminal Human ATP Citrate Lyase Bound to 4R-Hydroxycitrate
分子名称: 3-C-carboxy-2-deoxy-L-threo-pentaric acid, ATP-citrate synthase, PHOSPHATE ION, ...
著者Hu, J, Fraser, M.E.
登録日2016-09-20
公開日2017-08-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TDE
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BU of 5tde by Molmil
TEV Cleaved Human ATP Citrate Lyase Bound to Citrate
分子名称: ATP-citrate synthase, CITRATE ANION, DIHYDROGENPHOSPHATE ION, ...
著者Hu, J, Fraser, M.E.
登録日2016-09-19
公開日2017-08-09
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
5TDM
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BU of 5tdm by Molmil
TEV Cleaved Human ATP Citrate Lyase Bound to 4R-Hydroxycitrate and ADP
分子名称: 3-C-carboxy-2-deoxy-L-threo-pentaric acid, ADENOSINE, ADENOSINE-5'-DIPHOSPHATE, ...
著者Hu, J, Fraser, M.E.
登録日2016-09-19
公開日2017-08-09
最終更新日2017-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Binding of hydroxycitrate to human ATP-citrate lyase.
Acta Crystallogr D Struct Biol, 73, 2017
4MQT
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BU of 4mqt by Molmil
Structure of active human M2 muscarinic acetylcholine receptor bound to the agonist iperoxo and allosteric modulator LY2119620
分子名称: 3-amino-5-chloro-N-cyclopropyl-4-methyl-6-[2-(4-methylpiperazin-1-yl)-2-oxoethoxy]thieno[2,3-b]pyridine-2-carboxamide, 4-(4,5-dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethylbut-2-yn-1-aminium, Muscarinic acetylcholine receptor M2, ...
著者Kruse, A.C, Ring, A.M, Manglik, A, Hu, J, Hu, K, Eitel, K, Huebner, H, Pardon, E, Valant, C, Sexton, P.M, Christopoulos, A, Felder, C.C, Gmeiner, P, Steyaert, J, Weis, W.I, Garcia, K.C, Wess, J, Kobilka, B.K.
登録日2013-09-16
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Activation and allosteric modulation of a muscarinic acetylcholine receptor.
Nature, 504, 2013
5FBK
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BU of 5fbk by Molmil
Crystal structure of the extracellular domain of human calcium sensing receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, CHLORIDE ION, ...
著者Zhang, T, Zhang, C, Miller, C.L, Zou, J, Moremen, K.W, Brown, E.M, Yang, J.J, Hu, J.
登録日2015-12-14
公開日2016-06-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist.
Sci Adv, 2, 2016
6XJH
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BU of 6xjh by Molmil
PmtCD ABC exporter without the basket domain at C2 symmetry
分子名称: ABC transporter ATP-binding protein, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Zeytuni, N, Strynadka, N.J.C, Hu, J, Worrall, L.J, Chou, H, Yu, Z.
登録日2020-06-23
公開日2020-10-14
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural insight into the Staphylococcus aureus ATP-driven exporter of virulent peptide toxins
Sci Adv, 6, 2020
6XJI
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BU of 6xji by Molmil
PmtCD ABC exporter at C1 symmetry
分子名称: ABC transporter ATP-binding protein, MAGNESIUM ION, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ...
著者Zeytuni, N, Strynadka, N.J.C, Hu, J, Worrall, L.J, Chou, H, Yu, Z.
登録日2020-06-23
公開日2020-10-14
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Structural insight into the Staphylococcus aureus ATP-driven exporter of virulent peptide toxins
Sci Adv, 6, 2020
4FO9
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BU of 4fo9 by Molmil
Crystal structure of the E3 SUMO Ligase PIAS2
分子名称: E3 SUMO-protein ligase PIAS2, UNKNOWN ATOM OR ION, ZINC ION
著者Dong, A, Hu, J, Dobrovetsky, E, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC)
登録日2012-06-20
公開日2012-07-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Crystal structure of the E3 SUMO Ligase PIAS2
to be published
4MVT
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BU of 4mvt by Molmil
Crystal structure of SUMO E3 Ligase PIAS3
分子名称: CHLORIDE ION, E3 SUMO-protein ligase PIAS3, UNKNOWN ATOM OR ION, ...
著者Dong, A, Hu, J, Li, Y, Tempel, W, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC)
登録日2013-09-24
公開日2013-10-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of SUMO E3 Ligase PIAS3
to be published
4MQS
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BU of 4mqs by Molmil
Structure of active human M2 muscarinic acetylcholine receptor bound to the agonist iperoxo
分子名称: 4-(4,5-dihydro-1,2-oxazol-3-yloxy)-N,N,N-trimethylbut-2-yn-1-aminium, Muscarinic acetylcholine receptor M2, Nanobody 9-8
著者Kruse, A.C, Ring, A.M, Manglik, A, Hu, J, Hu, K, Eitel, K, Huebner, H, Pardon, E, Valant, C, Sexton, P.M, Christopoulos, A, Felder, C.C, Gmeiner, P, Steyaert, J, Weis, W.I, Garcia, K.C, Wess, J, Kobilka, B.K.
登録日2013-09-16
公開日2013-11-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Activation and allosteric modulation of a muscarinic acetylcholine receptor.
Nature, 504, 2013
1VSQ
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BU of 1vsq by Molmil
Solution NMR structure of the productive complex between IIAMannose and IIBMannose of the mannose transporter of the E. coli phosphotransferase system
分子名称: Mannose-specific phosphotransferase enzyme IIA component, Mannose-specific phosphotransferase enzyme IIB component
著者Clore, G.M, Hu, J, Hu, K.
登録日2008-01-10
公開日2008-02-19
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution NMR Structures of Productive and Non-productive Complexes between the A and B Domains of the Cytoplasmic Subunit of the Mannose Transporter of the Escherichia coli Phosphotransferase System.
J.Biol.Chem., 283, 2008
5CB2
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BU of 5cb2 by Molmil
the structure of candida albicans Sey1p in complex with GMPPNP
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Protein SEY1
著者Yan, L, Sun, S, Wang, W, Shi, J, Hu, X, Wang, S, Rao, Z, Hu, J, Lou, Z.
登録日2015-06-30
公開日2015-09-23
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of the yeast dynamin-like GTPase Sey1p provide insight into homotypic ER fusion
J.Cell Biol., 210, 2015
6PGI
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BU of 6pgi by Molmil
Asymmetric functions of a binuclear metal cluster within the transport pathway of the ZIP transition metal transporters
分子名称: BbZIP, CADMIUM ION
著者Zhang, T, Sui, D, Zhang, C, Logan, T, Hu, J.
登録日2019-06-24
公開日2019-12-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Asymmetric functions of a binuclear metal center within the transport pathway of a human zinc transporter ZIP4.
Faseb J., 34, 2020

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