5FBH
 
 | | Crystal structure of the extracellular domain of human calcium sensing receptor with bound Gd3+ | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, CHLORIDE ION, ... | | Authors: | Zhang, T, Zhang, C, Miller, C.L, Zou, J, Moremen, K.W, Brown, E.M, Yang, J.J, Hu, J. | | Deposit date: | 2015-12-14 | | Release date: | 2016-06-22 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis for regulation of human calcium-sensing receptor by magnesium ions and an unexpected tryptophan derivative co-agonist.
Sci Adv, 2, 2016
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3NYJ
 | | Crystal Structure Analysis of APP E2 domain | | Descriptor: | Amyloid beta A4 protein, OSMIUM ION | | Authors: | Ha, Y, Hu, J, Lee, S, Liu, X. | | Deposit date: | 2010-07-15 | | Release date: | 2011-06-01 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | The E2 Domains of APP and APLP1 Share a Conserved Mode of Dimerization.
Biochemistry, 50, 2011
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8UC2
 | | Ethylene forming enzyme (EFE) R171A variant in complex with nickel and Benzoic acid | | Descriptor: | 1,2-ETHANEDIOL, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, BENZOIC ACID, ... | | Authors: | Chatterjee, S, Rankin, J.A, Hu, J, Hausinger, R. | | Deposit date: | 2023-09-25 | | Release date: | 2023-10-04 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural, Spectroscopic, and Computational Insights from Canavanine-Bound and Two Catalytically Compromised Variants of the Ethylene-Forming Enzyme.
Biochemistry, 63, 2024
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3FP2
 | | Crystal structure of Tom71 complexed with Hsp82 C-terminal fragment | | Descriptor: | ATP-dependent molecular chaperone HSP82, CHLORIDE ION, MAGNESIUM ION, ... | | Authors: | Li, J, Qian, X, Hu, J, Sha, B. | | Deposit date: | 2009-01-03 | | Release date: | 2009-07-28 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Molecular chaperone Hsp70/Hsp90 prepares the mitochondrial outer membrane translocon receptor Tom71 for preprotein loading.
J.Biol.Chem., 284, 2009
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2NEF
 | | HIV-1 NEF (REGULATORY FACTOR), NMR, 40 STRUCTURES | | Descriptor: | NEGATIVE FACTOR (F-PROTEIN) | | Authors: | Grzesiek, S, Bax, A, Clore, G.M, Gronenborn, A.M, Hu, J.S, Kaufman, J, Palmer, I, Stahl, S.J, Tjandra, N, Wingfield, P.T. | | Deposit date: | 1997-02-12 | | Release date: | 1997-07-07 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Refined solution structure and backbone dynamics of HIV-1 Nef.
Protein Sci., 6, 1997
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3FP3
 | | Crystal structure of Tom71 | | Descriptor: | CHLORIDE ION, SULFATE ION, TPR repeat-containing protein YHR117W | | Authors: | Li, J, Qian, X, Hu, J, Sha, B. | | Deposit date: | 2009-01-03 | | Release date: | 2009-07-28 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Molecular chaperone Hsp70/Hsp90 prepares the mitochondrial outer membrane translocon receptor Tom71 for preprotein loading.
J.Biol.Chem., 284, 2009
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7WNT
 | | RNase J from Mycobacterium tuberculosis | | Descriptor: | Ribonuclease J, ZINC ION | | Authors: | Li, J, Bao, L, Hu, J, Zhan, B, Li, Z. | | Deposit date: | 2022-01-19 | | Release date: | 2023-01-25 | | Last modified: | 2024-09-04 | | Method: | X-RAY DIFFRACTION (2.44 Å) | | Cite: | Structural insights into RNase J that plays an essential role in Mycobacterium tuberculosis RNA metabolism
Nat Commun, 14, 2023
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7WNU
 | | Mycobacterium tuberculosis Rnase J complex with 7nt RNA | | Descriptor: | RNA (5'-R(P*AP*AP*AP*AP*AP*AP*A)-3'), Ribonuclease J, ZINC ION | | Authors: | Li, J, Hu, J, Bao, L, Zhan, B, Li, Z. | | Deposit date: | 2022-01-19 | | Release date: | 2023-01-25 | | Last modified: | 2024-09-04 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | Structural insights into RNase J that plays an essential role in Mycobacterium tuberculosis RNA metabolism
Nat Commun, 14, 2023
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3FP4
 | | Crystal structure of Tom71 complexed with Ssa1 C-terminal fragment | | Descriptor: | CHLORIDE ION, SODIUM ION, SULFATE ION, ... | | Authors: | Li, J, Qian, X, Hu, J, Sha, B. | | Deposit date: | 2009-01-03 | | Release date: | 2009-07-28 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.14 Å) | | Cite: | Molecular chaperone Hsp70/Hsp90 prepares the mitochondrial outer membrane translocon receptor Tom71 for preprotein loading.
J.Biol.Chem., 284, 2009
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4O2W
 | | Crystal structure of the third RCC1-like domain of HERC1 | | Descriptor: | CHLORIDE ION, E3 ubiquitin-protein ligase HERC1, MAGNESIUM ION, ... | | Authors: | Dong, A, Hu, J, Li, Y, Walker, J.R, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | | Deposit date: | 2013-12-17 | | Release date: | 2014-01-15 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of the third RCC1-like domain of HERC1
To be Published
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5C7M
 | | CRYSTAL STRUCTURE OF E3 LIGASE ITCH WITH A UB VARIANT | | Descriptor: | E3 ubiquitin-protein ligase Itchy homolog, Polyubiquitin-C | | Authors: | Walker, J.R, Hu, J, Dong, A, Wernimont, A, Zhang, W, Sidhu, S, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC) | | Deposit date: | 2015-06-24 | | Release date: | 2016-03-16 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.03 Å) | | Cite: | System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
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5C7J
 | | CRYSTAL STRUCTURE OF NEDD4 WITH A UB VARIANT | | Descriptor: | E3 ubiquitin-protein ligase NEDD4, Polyubiquitin-C | | Authors: | Walker, J.R, Hu, J, Dong, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Tong, Y, Structural Genomics Consortium (SGC) | | Deposit date: | 2015-06-24 | | Release date: | 2016-03-16 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.
Mol.Cell, 62, 2016
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6J72
 | | Crystal structure of IniA from Mycobacterium smegmatis with GTP bound | | Descriptor: | GUANOSINE-5'-TRIPHOSPHATE, Isoniazid inducible gene protein IniA, L(+)-TARTARIC ACID, ... | | Authors: | Wang, M.F, Guo, X.Y, Hu, J.J, Li, J, Rao, Z.H. | | Deposit date: | 2019-01-16 | | Release date: | 2019-09-11 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Mycobacterial dynamin-like protein IniA mediates membrane fission.
Nat Commun, 10, 2019
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6JFL
 | | Nucleotide-free Mitofusin2 (MFN2) | | Descriptor: | CALCIUM ION, GLYCEROL, Mitofusin-2,cDNA FLJ57997, ... | | Authors: | Li, Y.J, Cao, Y.L, Feng, J.X, Qi, Y.B, Meng, S.X, Yang, J.F, Zhong, Y.T, Kang, S.S, Chen, X.X, Lan, L, Luo, L, Yu, B, Chen, S.D, Chan, D.C, Hu, J.J, Gao, S. | | Deposit date: | 2019-02-10 | | Release date: | 2019-11-13 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.806 Å) | | Cite: | Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset.
Nat Commun, 10, 2019
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6JFM
 | | Mitofusin2 (MFN2)_T111D | | Descriptor: | ACETATE ION, CALCIUM ION, Mitofusin-2,Mitofusin-2 | | Authors: | Li, Y.J, Cao, Y.L, Feng, J.X, Qi, Y.B, Meng, S.X, Yang, J.F, Zhong, Y.T, Kang, S.S, Chen, X.X, Lan, L, Luo, L, Yu, B, Chen, S.D, Chan, D.C, Hu, J.J, Gao, S. | | Deposit date: | 2019-02-10 | | Release date: | 2019-11-13 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset.
Nat Commun, 10, 2019
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5HUQ
 | | A tethered niacin-derived pincer complex with a nickel-carbon bond in lactate racemase | | Descriptor: | 3-methanethioyl-1-(5-O-phosphono-beta-D-ribofuranosyl)-5-(sulfanylcarbonyl)pyridin-1-ium, Lactate racemization operon protein LarA, NICKEL (II) ION, ... | | Authors: | Desguin, B, Zhang, T, Soumillion, P, Hols, P, Hu, J, Hausinger, R.P. | | Deposit date: | 2016-01-27 | | Release date: | 2016-02-10 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | METALLOPROTEINS. A tethered niacin-derived pincer complex with a nickel-carbon bond in lactate racemase.
Science, 349, 2015
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6JFK
 | | GDP bound Mitofusin2 (MFN2) | | Descriptor: | CITRIC ACID, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | | Authors: | Li, Y.J, Cao, Y.L, Feng, J.X, Qi, Y.B, Meng, S.X, Yang, J.F, Zhong, Y.T, Kang, S.S, Chen, X.X, Lan, L, Luo, L, Yu, B, Chen, S.D, Chan, D.C, Hu, J.J, Gao, S. | | Deposit date: | 2019-02-10 | | Release date: | 2019-11-13 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (1.997 Å) | | Cite: | Structural insights of human mitofusin-2 into mitochondrial fusion and CMT2A onset.
Nat Commun, 10, 2019
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6J73
 | | Crystal structure of IniA from Mycobacterium smegmatis | | Descriptor: | Isoniazid inducible gene protein IniA | | Authors: | Wang, M.F, Guo, X.Y, Hu, J.J, Li, J, Rao, Z.H. | | Deposit date: | 2019-01-16 | | Release date: | 2019-09-11 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (3.211 Å) | | Cite: | Mycobacterial dynamin-like protein IniA mediates membrane fission.
Nat Commun, 10, 2019
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5GNR
 | | the structure of mini-MFN1 K88A in complex with GDP | | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Mitofusin-1 | | Authors: | Yan, L, Yu, C, Ming, Z, Lou, Z, Rao, Z, Hu, J. | | Deposit date: | 2016-07-24 | | Release date: | 2016-11-23 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.65 Å) | | Cite: | BDLP-like folding of Mitofusin 1
To Be Published
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4JUY
 | | Crystal structure of the PUB domain of E3 ubiquitin ligase RNF31 | | Descriptor: | E3 ubiquitin-protein ligase RNF31, UNKNOWN ATOM OR ION | | Authors: | Dong, A, Hu, J, Li, Y, Wernimont, A, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | | Deposit date: | 2013-03-25 | | Release date: | 2013-04-10 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.4 Å) | | Cite: | Crystal structure of the PUB domain of E3 ubiquitin ligase RNF31
To be Published
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4KFV
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4L1M
 | | Structure of the first RCC1-like domain of HERC2 | | Descriptor: | E3 ubiquitin-protein ligase HERC2, SULFATE ION, UNKNOWN ATOM OR ION | | Authors: | Tempel, W, Khan, M.B, Dong, A, Hu, J, Li, Y, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Tong, Y, Structural Genomics Consortium (SGC) | | Deposit date: | 2013-06-03 | | Release date: | 2013-07-03 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structure of the first RCC1-like domain of HERC2
TO BE PUBLISHED
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4KFW
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6B2M
 | | LarE, a sulfur transferase involved in synthesis of the cofactor for lactate racemase in complex with coenzyme A | | Descriptor: | ATP-utilizing enzyme of the PP-loopsuperfamily, COENZYME A, PHOSPHATE ION | | Authors: | Fellner, M, Hausinger, R.P, Hu, J. | | Deposit date: | 2017-09-20 | | Release date: | 2018-09-05 | | Last modified: | 2023-10-04 | | Method: | X-RAY DIFFRACTION (2.088 Å) | | Cite: | Analysis of the Active Site Cysteine Residue of the Sacrificial Sulfur Insertase LarE from Lactobacillus plantarum.
Biochemistry, 57, 2018
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6CF3
 | | Ethylene forming enzyme Y306A variant in complex with manganese and 2-oxoglutarate | | Descriptor: | 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, 2-oxoglutarate-dependent ethylene/succinate-forming enzyme, ... | | Authors: | Fellner, M, Martinez, S, Hu, J, Hausinger, R.P. | | Deposit date: | 2018-02-13 | | Release date: | 2019-02-13 | | Last modified: | 2024-04-17 | | Method: | X-RAY DIFFRACTION (1.12 Å) | | Cite: | Structural, Spectroscopic, and Computational Insights from Canavanine-Bound and Two Catalytically Compromised Variants of the Ethylene-Forming Enzyme.
Biochemistry, 2024
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