3GBK
| Crystal Structure of Human PPAR-gamma Ligand Binding Domain Complexed with a Potent and Selective Agonist | 分子名称: | 2-[(1-{3-[4-(biphenyl-4-ylcarbonyl)-2-propylphenoxy]propyl}-1,2,3,4-tetrahydroquinolin-5-yl)oxy]-2-methylpropanoic acid, Peroxisome proliferator-activated receptor gamma | 著者 | Peng, Y.-H, Lin, C.-H, Hsieh, H.-P, Wu, S.-Y. | 登録日 | 2009-02-19 | 公開日 | 2009-12-29 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Design and structural analysis of novel pharmacophores for potent and selective peroxisome proliferator-activated receptor gamma agonists J.Med.Chem., 52, 2009
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2ATH
| Crystal structure of the ligand binding domain of human PPAR-gamma im complex with an agonist | 分子名称: | 2-{5-[3-(7-PROPYL-3-TRIFLUOROMETHYLBENZO[D]ISOXAZOL-6-YLOXY)PROPOXY]INDOL-1-YL}ETHANOIC ACID, Peroxisome proliferator activated receptor gamma | 著者 | Mahindroo, N, Huang, C.-F, Wu, S.-Y, Hsieh, H.-P. | 登録日 | 2005-08-25 | 公開日 | 2006-08-25 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Novel indole-based peroxisome proliferator-activated receptor agonists: design, SAR, structural biology, and biological activities J.Med.Chem., 48, 2005
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