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PDB: 25 results

5DK5
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BU of 5dk5 by Molmil
Crystal structure of CRN-4-MES complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cell death-related nuclease 4, ISOPROPYL ALCOHOL, ...
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2015-09-03
Release date:2016-08-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Identification of Inhibitors for the DEDDh Family of Exonucleases and a Unique Inhibition Mechanism by Crystal Structure Analysis of CRN-4 Bound with 2-Morpholin-4-ylethanesulfonate (MES)
J.Med.Chem., 59, 2016
4KB1
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BU of 4kb1 by Molmil
Crystal structure of RNase T in complex with a bluge DNA (two nucleotide insertion CT )
Descriptor: Bulge DNA, MAGNESIUM ION, Ribonuclease T
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2013-04-23
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural insights into DNA repair by RNase T--an exonuclease processing 3' end of structured DNA in repair pathways.
Plos Biol., 12, 2014
4KAZ
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BU of 4kaz by Molmil
Crystal structure of RNase T in complex with a Y structured DNA
Descriptor: DNA (5'-D(*TP*TP*GP*GP*CP*CP*CP*TP*CP*TP*TP*TP*AP*GP*GP*GP*CP*CP*CP*C)-3'), MAGNESIUM ION, Ribonuclease T
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2013-04-23
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into DNA repair by RNase T--an exonuclease processing 3' end of structured DNA in repair pathways.
Plos Biol., 12, 2014
4KB0
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BU of 4kb0 by Molmil
Crystal structure of RNase T in complex with a bluge DNA (Two nucleotide insertion CC )
Descriptor: DNA (5'-D(*GP*GP*CP*CP*CP*TP*CP*TP*TP*TP*AP*GP*GP*GP*CP*CP*CP*C)-3'), MAGNESIUM ION, Ribonuclease T
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2013-04-23
Release date:2014-03-05
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.004 Å)
Cite:Structural insights into DNA repair by RNase T--an exonuclease processing 3' end of structured DNA in repair pathways.
Plos Biol., 12, 2014
3CG7
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BU of 3cg7 by Molmil
Crystal structure of cell-death related nuclease 4 (CRN-4)
Descriptor: Cell death-related nuclease 4, ZINC ION
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2008-03-05
Release date:2008-12-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of CRN-4: implications for domain function in apoptotic DNA degradation
Mol.Cell.Biol., 29, 2009
3CM5
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BU of 3cm5 by Molmil
Crystal structure of Cell-Death Related Nuclease 4 (CRN-4) bound with Mn
Descriptor: Cell death-related nuclease 4, MANGANESE (II) ION, ZINC ION
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2008-03-21
Release date:2008-12-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Crystal structure of CRN-4: implications for domain function in apoptotic DNA degradation
Mol.Cell.Biol., 29, 2009
3CM6
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BU of 3cm6 by Molmil
Crystal structure of cell-death related nuclease 4 (CRN-4) bound with Er
Descriptor: Cell death-related nuclease 4, ERBIUM (III) ION, ZINC ION
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2008-03-21
Release date:2008-12-30
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of CRN-4: implications for domain function in apoptotic DNA degradation
Mol.Cell.Biol., 29, 2009
3NH0
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BU of 3nh0 by Molmil
Crystal structure of RNase T in complex with a non-preferred ssDNA (AAC)
Descriptor: 5'-D(*TP*TP*AP*CP*AP*AP*C)-3', Ribonuclease T
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2010-06-14
Release date:2011-02-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation
Nat.Chem.Biol., 7, 2011
3NGZ
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BU of 3ngz by Molmil
Crystal structure of RNase T in complex with a non-preferred ssDNA (GC) with one Mg in the active site
Descriptor: 5'-D(P*GP*C)-3', COBALT (II) ION, MAGNESIUM ION, ...
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2010-06-14
Release date:2011-02-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation
Nat.Chem.Biol., 7, 2011
3NH2
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BU of 3nh2 by Molmil
Crystal structure of RNase T in complex with a stem DNA with a 3' overhang
Descriptor: 5'-D(P*TP*TP*AP*CP*AP*AP*C)-3', Ribonuclease T
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2010-06-14
Release date:2011-02-16
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation
Nat.Chem.Biol., 7, 2011
3NGY
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BU of 3ngy by Molmil
Crystal structure of RNase T (E92G mutant)
Descriptor: COBALT (II) ION, Ribonuclease T, his tag sequence
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2010-06-14
Release date:2011-02-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.204 Å)
Cite:Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation
Nat.Chem.Biol., 7, 2011
3NH1
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BU of 3nh1 by Molmil
Crystal structure of RNase T in complex with a preferred ssDNA (TAGG) with two Mg in the active site
Descriptor: 5'-D(*TP*TP*AP*TP*AP*GP*G)-3', MAGNESIUM ION, Ribonuclease T
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2010-06-14
Release date:2011-02-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.107 Å)
Cite:Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation
Nat.Chem.Biol., 7, 2011
3V9W
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BU of 3v9w by Molmil
Crystal structure of RNase T in complex with a preferred ssDNA (TTA) with two Mg in the active site
Descriptor: COBALT (II) ION, DNA (5'-D(*GP*CP*TP*TP*A)-3'), MAGNESIUM ION, ...
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2011-12-28
Release date:2012-07-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.702 Å)
Cite:How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes
Nucleic Acids Res., 40, 2012
3V9X
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BU of 3v9x by Molmil
Crystal structure of RNase T in complex with a preferred ssDNA (AAA) with two Mg in the active site
Descriptor: DNA (5'-D(*TP*TP*AP*TP*AP*AP*A)-3'), MAGNESIUM ION, Ribonuclease T
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2011-12-28
Release date:2012-07-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes
Nucleic Acids Res., 40, 2012
3VA0
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BU of 3va0 by Molmil
Crystal structure of RNase T in complex with a di-nucleotide product (GG) with one Mg in the active site
Descriptor: COBALT (II) ION, DNA (5'-D(*GP*G)-3'), MAGNESIUM ION, ...
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2011-12-28
Release date:2012-07-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.201 Å)
Cite:How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes
Nucleic Acids Res., 40, 2012
3V9Z
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BU of 3v9z by Molmil
Crystal structure of RNase T in complex with a product ssDNA (ACC) with one Mg in the active site
Descriptor: COBALT (II) ION, DNA (5'-D(*TP*TP*AP*CP*AP*CP*C)-3'), MAGNESIUM ION, ...
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2011-12-28
Release date:2012-07-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes
Nucleic Acids Res., 40, 2012
3V9S
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BU of 3v9s by Molmil
Crystal structure of RNase T in complex with a product ssDNA (AAC) with one Mg in the active site
Descriptor: COBALT (II) ION, DNA (5'-D(*TP*TP*AP*CP*AP*AP*C)-3'), MAGNESIUM ION, ...
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2011-12-28
Release date:2012-07-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes
Nucleic Acids Res., 40, 2012
3V9U
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BU of 3v9u by Molmil
Crystal structure of RNase T in complex with a preferred ssDNA (AAT) with two Mg in the active site
Descriptor: COBALT (II) ION, DNA (5'-D(*TP*TP*AP*CP*AP*AP*T)-3'), MAGNESIUM ION, ...
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2011-12-28
Release date:2012-07-11
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.298 Å)
Cite:How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes
Nucleic Acids Res., 40, 2012
3VA3
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BU of 3va3 by Molmil
Crystal structure of RNase T in complex with a duplex DNA product (stem loop DNA with 2 nucleotide 3' overhang)
Descriptor: COBALT (II) ION, DNA (5'-D(*GP*GP*CP*CP*CP*TP*CP*TP*TP*TP*AP*GP*GP*GP*CP*CP*TP*T)-3'), Ribonuclease T
Authors:Hsiao, Y.-Y, Yuan, H.S.
Deposit date:2011-12-28
Release date:2012-07-11
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.714 Å)
Cite:How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes
Nucleic Acids Res., 40, 2012
5GYJ
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BU of 5gyj by Molmil
Structure of catalytically active sortase from Clostridium difficile
Descriptor: Putative peptidase C60B, sortase B
Authors:Yin, J.-C, Fei, C.-H, Hsiao, Y.-Y, Nix, J.C, Huang, I.-H, Wang, S.
Deposit date:2016-09-22
Release date:2017-01-04
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.801 Å)
Cite:Structural Insights into Substrate Recognition by Clostridium difficile Sortase.
Front Cell Infect Microbiol, 6, 2016
1M07
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BU of 1m07 by Molmil
RESIDUES INVOLVED IN THE CATALYSIS AND BASE SPECIFICITY OF CYTOTOXIC RIBONUCLEASE FROM BULLFROG (RANA CATESBEIANA)
Descriptor: 5'-D(*AP*CP*GP*A)-3', Ribonuclease
Authors:Leu, Y.-J, Chern, S.-S, Wang, S.-C, Hsiao, Y.-Y, Amiraslanov, I, Liaw, Y.-C, Liao, Y.-D.
Deposit date:2002-06-12
Release date:2003-01-21
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Residues involved in the catalysis, base specificity, and cytotoxicity of ribonuclease from Rana catesbeiana based upon mutagenesis and X-ray crystallography
J.Biol.Chem., 278, 2003
4PE8
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BU of 4pe8 by Molmil
Crystal structure of TatD in complex with trinucleotide DNA
Descriptor: DNA (5'-D(*GP*CP*T)-3'), Tat-linked quality control protein TatD
Authors:Chen, Y, Li, C.-L, Hsiao, Y.-Y, Duh, Y, Yuan, H.S.
Deposit date:2014-04-23
Release date:2014-08-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.894 Å)
Cite:Structure and function of TatD exonuclease in DNA repair.
Nucleic Acids Res., 42, 2014
4P5U
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BU of 4p5u by Molmil
Crystal structure of TatD
Descriptor: Tat-linked quality control protein TatD
Authors:Chen, Y, Li, C.-L, Hsiao, Y.-Y, Duh, Y, Yuan, H.S.
Deposit date:2014-03-20
Release date:2014-08-27
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and function of TatD exonuclease in DNA repair.
Nucleic Acids Res., 42, 2014
3HKM
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BU of 3hkm by Molmil
Crystal Structure of rice(Oryza sativa) Rrp46
Descriptor: Os03g0854200 protein
Authors:Yang, C.-C, Wang, Y.-T, Hsiao, Y.-Y, Doudeva, L.G, Yuan, H.S.
Deposit date:2009-05-25
Release date:2010-01-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (1.9845 Å)
Cite:Structural and biochemical characterization of CRN-5 and Rrp46: an exosome component participating in apoptotic DNA degradation
Rna, 16, 2010
3KRN
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BU of 3krn by Molmil
Crystal Structure of C. elegans cell-death-related nuclease 5(CRN-5)
Descriptor: Protein C14A4.5, confirmed by transcript evidence
Authors:Yang, C.-C, Wang, Y.-T, Hsiao, Y.-Y, Doudeva, L.G, Chow, S.Y, Yuan, H.S.
Deposit date:2009-11-19
Release date:2010-01-26
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.918 Å)
Cite:Structural and biochemical characterization of CRN-5 and Rrp46: an exosome component participating in apoptotic DNA degradation
Rna, 16, 2010

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