5DK5
| Crystal structure of CRN-4-MES complex | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cell death-related nuclease 4, ISOPROPYL ALCOHOL, ... | Authors: | Hsiao, Y.-Y, Yuan, H.S. | Deposit date: | 2015-09-03 | Release date: | 2016-08-24 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Identification of Inhibitors for the DEDDh Family of Exonucleases and a Unique Inhibition Mechanism by Crystal Structure Analysis of CRN-4 Bound with 2-Morpholin-4-ylethanesulfonate (MES) J.Med.Chem., 59, 2016
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4KB1
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4KAZ
| Crystal structure of RNase T in complex with a Y structured DNA | Descriptor: | DNA (5'-D(*TP*TP*GP*GP*CP*CP*CP*TP*CP*TP*TP*TP*AP*GP*GP*GP*CP*CP*CP*C)-3'), MAGNESIUM ION, Ribonuclease T | Authors: | Hsiao, Y.-Y, Yuan, H.S. | Deposit date: | 2013-04-23 | Release date: | 2014-03-05 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural insights into DNA repair by RNase T--an exonuclease processing 3' end of structured DNA in repair pathways. Plos Biol., 12, 2014
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4KB0
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3CG7
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3CM5
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3CM6
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3NH0
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3NGZ
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3NH2
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3NGY
| Crystal structure of RNase T (E92G mutant) | Descriptor: | COBALT (II) ION, Ribonuclease T, his tag sequence | Authors: | Hsiao, Y.-Y, Yuan, H.S. | Deposit date: | 2010-06-14 | Release date: | 2011-02-16 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.204 Å) | Cite: | Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation Nat.Chem.Biol., 7, 2011
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3NH1
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3V9W
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3V9X
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3VA0
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3V9Z
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3V9S
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3V9U
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3VA3
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5GYJ
| Structure of catalytically active sortase from Clostridium difficile | Descriptor: | Putative peptidase C60B, sortase B | Authors: | Yin, J.-C, Fei, C.-H, Hsiao, Y.-Y, Nix, J.C, Huang, I.-H, Wang, S. | Deposit date: | 2016-09-22 | Release date: | 2017-01-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.801 Å) | Cite: | Structural Insights into Substrate Recognition by Clostridium difficile Sortase. Front Cell Infect Microbiol, 6, 2016
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1M07
| RESIDUES INVOLVED IN THE CATALYSIS AND BASE SPECIFICITY OF CYTOTOXIC RIBONUCLEASE FROM BULLFROG (RANA CATESBEIANA) | Descriptor: | 5'-D(*AP*CP*GP*A)-3', Ribonuclease | Authors: | Leu, Y.-J, Chern, S.-S, Wang, S.-C, Hsiao, Y.-Y, Amiraslanov, I, Liaw, Y.-C, Liao, Y.-D. | Deposit date: | 2002-06-12 | Release date: | 2003-01-21 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Residues involved in the catalysis, base specificity, and cytotoxicity of ribonuclease from Rana catesbeiana based upon mutagenesis and X-ray crystallography J.Biol.Chem., 278, 2003
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4PE8
| Crystal structure of TatD in complex with trinucleotide DNA | Descriptor: | DNA (5'-D(*GP*CP*T)-3'), Tat-linked quality control protein TatD | Authors: | Chen, Y, Li, C.-L, Hsiao, Y.-Y, Duh, Y, Yuan, H.S. | Deposit date: | 2014-04-23 | Release date: | 2014-08-27 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.894 Å) | Cite: | Structure and function of TatD exonuclease in DNA repair. Nucleic Acids Res., 42, 2014
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4P5U
| Crystal structure of TatD | Descriptor: | Tat-linked quality control protein TatD | Authors: | Chen, Y, Li, C.-L, Hsiao, Y.-Y, Duh, Y, Yuan, H.S. | Deposit date: | 2014-03-20 | Release date: | 2014-08-27 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure and function of TatD exonuclease in DNA repair. Nucleic Acids Res., 42, 2014
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3HKM
| Crystal Structure of rice(Oryza sativa) Rrp46 | Descriptor: | Os03g0854200 protein | Authors: | Yang, C.-C, Wang, Y.-T, Hsiao, Y.-Y, Doudeva, L.G, Yuan, H.S. | Deposit date: | 2009-05-25 | Release date: | 2010-01-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9845 Å) | Cite: | Structural and biochemical characterization of CRN-5 and Rrp46: an exosome component participating in apoptotic DNA degradation Rna, 16, 2010
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3KRN
| Crystal Structure of C. elegans cell-death-related nuclease 5(CRN-5) | Descriptor: | Protein C14A4.5, confirmed by transcript evidence | Authors: | Yang, C.-C, Wang, Y.-T, Hsiao, Y.-Y, Doudeva, L.G, Chow, S.Y, Yuan, H.S. | Deposit date: | 2009-11-19 | Release date: | 2010-01-26 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.918 Å) | Cite: | Structural and biochemical characterization of CRN-5 and Rrp46: an exosome component participating in apoptotic DNA degradation Rna, 16, 2010
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