8JBP
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![BU of 8jbp by Molmil](/molmil-images/mine/8jbp) | Crystal structure of triosephosphate isomerase from Leishmania orientalis at 1.45 angstroms resolution with an arsenic atom bound at Cys57 | Descriptor: | ARSENIC, Triosephosphate isomerase | Authors: | Kuaprasert, B, Leartsakulpanich, U, Riangrungroj, P, Pornthanakasem, W, Suginta, W, Robinson, R.C, Zhou, Y, Mungthin, M, Leelayoova, S, Saehlee, S, Choowongkomon, K. | Deposit date: | 2023-05-09 | Release date: | 2024-05-15 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Leishmania orientalis triosephosphate isomerase crystal structure at 1.45 angstroms resolution and its potential specific inhibitors To be published
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5N15
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![BU of 5n15 by Molmil](/molmil-images/mine/5n15) | First Bromodomain (BD1) from Candida albicans Bdf1 in the unbound form | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Bromodomain-containing factor 1, GLYCEROL, ... | Authors: | Mietton, F, Ferri, E, Champleboux, M, Zala, N, Maubon, D, Zhou, Y, Harbut, M, Spittler, D, Garnaud, C, Courcon, M, Chauvel, M, d'Enfert, C, Kashemirov, B.A, Hull, M, Cornet, M, McKenna, C.E, Govin, J, Petosa, C. | Deposit date: | 2017-02-05 | Release date: | 2017-05-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Selective BET bromodomain inhibition as an antifungal therapeutic strategy. Nat Commun, 8, 2017
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6MDR
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![BU of 6mdr by Molmil](/molmil-images/mine/6mdr) | Cryo-EM structure of the Ceru+32/GFP-17 protomer | Descriptor: | Ceru+32, GFP-17 | Authors: | Simon, A.J, Zhou, Y, Ramasubramani, V, Glaser, J, Pothukuchy, A, Golihar, J, Gerberich, J.C, Leggere, J.C, Morrow, B.R, Jung, C, Glotzer, S.C, Taylor, D.W, Ellington, A.D. | Deposit date: | 2018-09-05 | Release date: | 2019-01-23 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | Supercharging enables organized assembly of synthetic biomolecules. Nat Chem, 11, 2019
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8GXN
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![BU of 8gxn by Molmil](/molmil-images/mine/8gxn) | The crystal structure of CsFAOMT2 in complex with SAH | Descriptor: | MAGNESIUM ION, S-ADENOSYL-L-HOMOCYSTEINE, caffeyl-CoA-O-methyltransferase | Authors: | Zhang, Z.M, Zhou, Y.E, Huang, H.S. | Deposit date: | 2022-09-20 | Release date: | 2023-09-20 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.34 Å) | Cite: | Characterization of two O-methyltransferases involved in the biosynthesis of O-methylated catechins in tea plant. Nat Commun, 14, 2023
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8GXO
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![BU of 8gxo by Molmil](/molmil-images/mine/8gxo) | |
5N16
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![BU of 5n16 by Molmil](/molmil-images/mine/5n16) | First Bromodomain (BD1) from Candida albicans Bdf1 bound to a dibenzothiazepinone (compound 1) | Descriptor: | 5-cyclopropyl-2-(5-pyrazin-2-yl-1,2,4-oxadiazol-3-yl)benzo[b][1,4]benzothiazepin-6-one, Bromodomain-containing factor 1, GLYCEROL, ... | Authors: | Mietton, F, Ferri, E, Champleboux, M, Zala, N, Maubon, D, Zhou, Y, Harbut, M, Spittler, D, Garnaud, C, Courcon, M, Chauvel, M, d'Enfert, C, Kashemirov, B.A, Hull, M, Cornet, M, McKenna, C.E, Govin, J, Petosa, C. | Deposit date: | 2017-02-05 | Release date: | 2017-05-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Selective BET bromodomain inhibition as an antifungal therapeutic strategy. Nat Commun, 8, 2017
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5N13
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![BU of 5n13 by Molmil](/molmil-images/mine/5n13) | Second Bromodomain (BD2) from Candida albicans Bdf1 in the unbound form | Descriptor: | Bromodomain-containing factor 1, GLYCEROL | Authors: | Mietton, F, Ferri, E, Champlebouxm, M, Zala, N, Maubon, D, Zhou, Y, Harbut, M, Spittler, D, Garnaud, C, Courcon, M, Chauvel, M, d'Enfert, C, Kashemirov, B.A, Hull, M, Cornet, M, McKenna, C.E, Govin, J, Petosa, C. | Deposit date: | 2017-02-04 | Release date: | 2017-05-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | Selective BET bromodomain inhibition as an antifungal therapeutic strategy. Nat Commun, 8, 2017
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5N17
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![BU of 5n17 by Molmil](/molmil-images/mine/5n17) | First Bromodomain (BD1) from Candida albicans Bdf1 bound to a dibenzothiazepinone (compound 3) | Descriptor: | (2~{S})-~{N}-(5-methyl-6-oxidanylidene-benzo[b][1,4]benzothiazepin-2-yl)oxolane-2-carboxamide, Bromodomain-containing factor 1, SULFATE ION | Authors: | Mietton, F, Ferri, E, Champleboux, M, Zala, N, Maubon, D, Zhou, Y, Harbut, M, Spittler, D, Garnaud, C, Courcon, M, Chauvon, M, d'Enfer, C, Kashemirov, B.A, Hull, M, Cornet, M, McKenna, C.E, Govin, J, Petosa, C. | Deposit date: | 2017-02-05 | Release date: | 2017-05-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Selective BET bromodomain inhibition as an antifungal therapeutic strategy. Nat Commun, 8, 2017
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5N18
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![BU of 5n18 by Molmil](/molmil-images/mine/5n18) | Second Bromodomain (BD2) from Candida albicans Bdf1 bound to an imidazopyridine (compound 2) | Descriptor: | 4-[8-methyl-3-[(4-methylphenyl)amino]imidazo[1,2-a]pyridin-2-yl]phenol, Bromodomain-containing factor 1, GLYCEROL | Authors: | Mietton, F, Ferri, E, Champleboux, M, Zala, N, Maubon, D, Zhou, Y, Harbut, M, Spittler, D, Garnaud, C, Courcon, M, Chauvel, M, d'Enfert, C, Kashemirov, B.A, Hull, M, Cornet, M, McKenna, C.E, Govin, J, Petosa, C. | Deposit date: | 2017-02-05 | Release date: | 2017-05-31 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Selective BET bromodomain inhibition as an antifungal therapeutic strategy. Nat Commun, 8, 2017
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8C9M
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![BU of 8c9m by Molmil](/molmil-images/mine/8c9m) | HERV-K Gag immature lattice | Descriptor: | Gag protein | Authors: | Krebs, A.-S, Liu, H.-F, Zhou, Y, Rey, J.S, Levintov, L, Perilla, J.R, Bartesaghi, A, Zhang, P. | Deposit date: | 2023-01-23 | Release date: | 2023-02-01 | Last modified: | 2023-07-05 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Molecular architecture and conservation of an immature human endogenous retrovirus. Biorxiv, 2023
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6DCX
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![BU of 6dcx by Molmil](/molmil-images/mine/6dcx) | iASPP-PP-1c structure and targeting of p53 | Descriptor: | RelA-associated inhibitor, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit | Authors: | Glover, J.N.M, Zhou, Y, Edwards, R.A. | Deposit date: | 2018-05-08 | Release date: | 2019-05-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.408 Å) | Cite: | Flexible Tethering of ASPP Proteins Facilitates PP-1c Catalysis. Structure, 27, 2019
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8HE4
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![BU of 8he4 by Molmil](/molmil-images/mine/8he4) | The structure of chitin deacetylase Pst_13661 from Puccinia striiformis f. sp. tritici | Descriptor: | Chitin deacetylase, ZINC ION, ~{N}-oxidanylnaphthalene-1-carboxamide | Authors: | Liu, L, Li, Y.C, Zhou, Y, Yang, Q. | Deposit date: | 2022-11-07 | Release date: | 2023-05-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Inhibition of chitin deacetylases to attenuate plant fungal diseases. Nat Commun, 14, 2023
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8HE2
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![BU of 8he2 by Molmil](/molmil-images/mine/8he2) | The structure of chitin deacetylase Pst_13661 from Puccinia striiformis f. sp. tritici | Descriptor: | Chitin deacetylase, ZINC ION, tert-butyl N-[3-[[4-(oxidanylcarbamoyl)phenyl]methylamino]-3-oxidanylidene-propyl]carbamate | Authors: | Liu, L, Li, Y.C, Zhou, Y, Yang, Q. | Deposit date: | 2022-11-07 | Release date: | 2023-05-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Inhibition of chitin deacetylases to attenuate plant fungal diseases. Nat Commun, 14, 2023
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8HE1
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![BU of 8he1 by Molmil](/molmil-images/mine/8he1) | The structure of chitin deacetylase Pst_13661 from Puccinia striiformis f. sp. tritici | Descriptor: | BENZHYDROXAMIC ACID, Chitin deacetylase, ZINC ION | Authors: | Liu, L, Li, Y.C, Zhou, Y, Yang, Q. | Deposit date: | 2022-11-07 | Release date: | 2023-05-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Inhibition of chitin deacetylases to attenuate plant fungal diseases. Nat Commun, 14, 2023
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8HFA
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![BU of 8hfa by Molmil](/molmil-images/mine/8hfa) | |
8HF9
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![BU of 8hf9 by Molmil](/molmil-images/mine/8hf9) | The structure of chitin deacetylase Pst_13661 from Puccinia striiformis f. sp. tritici | Descriptor: | Chitin deacetylase, ZINC ION | Authors: | Liu, L, Li, Y.C, Zhou, Y, Yang, Q. | Deposit date: | 2022-11-10 | Release date: | 2023-05-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.96 Å) | Cite: | Inhibition of chitin deacetylases to attenuate plant fungal diseases. Nat Commun, 14, 2023
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8HTD
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![BU of 8htd by Molmil](/molmil-images/mine/8htd) | Crystal structure of an effector from Chromobacterium violaceum in complex with ubiquitin | Descriptor: | NAD(+)--protein-threonine ADP-ribosyltransferase, Ubiquitin | Authors: | Tan, J, Wang, X, Zhou, Y, Zhu, Y. | Deposit date: | 2022-12-21 | Release date: | 2023-11-22 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.848 Å) | Cite: | Molecular basis of threonine ADP-ribosylation of ubiquitin by bacterial ARTs. Nat.Chem.Biol., 20, 2024
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8HTC
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![BU of 8htc by Molmil](/molmil-images/mine/8htc) | Crystal structure of a SeMet-labeled effector from Chromobacterium violaceum in complex with Ubiquitin | Descriptor: | NAD(+)--protein-threonine ADP-ribosyltransferase, Ubiquitin-40S ribosomal protein S27a (Fragment) | Authors: | Tan, J, Wang, X, Zhou, Y, Zhu, Y. | Deposit date: | 2022-12-21 | Release date: | 2023-11-22 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Molecular basis of threonine ADP-ribosylation of ubiquitin by bacterial ARTs. Nat.Chem.Biol., 20, 2024
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8HTE
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![BU of 8hte by Molmil](/molmil-images/mine/8hte) | Crystal structure of an effector mutant in complex with ubiquitin | Descriptor: | GLYCEROL, NAD(+)--protein-threonine ADP-ribosyltransferase, NICOTINAMIDE, ... | Authors: | Tan, J, Wang, X, Zhou, Y, Zhu, Y. | Deposit date: | 2022-12-21 | Release date: | 2023-11-22 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.307 Å) | Cite: | Molecular basis of threonine ADP-ribosylation of ubiquitin by bacterial ARTs. Nat.Chem.Biol., 20, 2024
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8HTF
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![BU of 8htf by Molmil](/molmil-images/mine/8htf) | Crystal structure of an effector in complex with ubiquitin | Descriptor: | NAD(+)--protein-threonine ADP-ribosyltransferase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Ubiquitin-40S ribosomal protein S27a (Fragment) | Authors: | Tan, J, Wang, X, Zhou, Y, Zhu, Y. | Deposit date: | 2022-12-21 | Release date: | 2023-11-22 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (2.151 Å) | Cite: | Molecular basis of threonine ADP-ribosylation of ubiquitin by bacterial ARTs. Nat.Chem.Biol., 20, 2024
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6ZUS
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![BU of 6zus by Molmil](/molmil-images/mine/6zus) | Crystal structure of the effector Ecp11-1 from Fulvia fulva | Descriptor: | DI(HYDROXYETHYL)ETHER, Extracellular protein 11-1, GLYCEROL, ... | Authors: | Lazar, N, Mesarich, C, Petit-Houdenot, Y, Talbi, N, Li de la Sierra-Gallay, I, Zelie, E, Blondeau, K, Gracy, J, Ollivier, B, van de Wouw, A, Balesdent, M.H, Idnurm, A, van Tilbeurgh, H, Fudal, I. | Deposit date: | 2020-07-23 | Release date: | 2021-08-04 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | A new family of structurally conserved fungal effectors displays epistatic interactions with plant resistance proteins. Plos Pathog., 18, 2022
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6ZUQ
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![BU of 6zuq by Molmil](/molmil-images/mine/6zuq) | Crystal structure of the effector Ecp11-1 from Fulvia fulva | Descriptor: | Extracellular protein 11-1, GLYCEROL, ZINC ION | Authors: | Lazar, N, Mesarich, C, Petit-Houdenot, Y, Talbi, N, Li de la Sierra-Gallay, I, Zelie, E, Blondeau, K, Gracy, J, Ollivier, B, van de Wouw, A, Balesdent, M.H, Idnurm, A, van Tilbeurgh, H, Fudal, I. | Deposit date: | 2020-07-23 | Release date: | 2021-08-04 | Last modified: | 2022-07-27 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | A new family of structurally conserved fungal effectors displays epistatic interactions with plant resistance proteins. Plos Pathog., 18, 2022
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5JDB
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![BU of 5jdb by Molmil](/molmil-images/mine/5jdb) | Binding specificity of P[8] VP8* proteins of rotavirus vaccine strains with histo-blood group antigens | Descriptor: | Outer capsid protein VP4 | Authors: | Sun, X, Guo, N, Li, D, Zhou, Y, Jin, M, Xie, G, Pang, L, Zhang, Q, Cao, Y, Duan, Z. | Deposit date: | 2016-04-16 | Release date: | 2016-07-13 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.901 Å) | Cite: | Binding specificity of P[8] VP8* proteins of rotavirus vaccine strains with histo-blood group antigens. Virology, 495, 2016
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7F5G
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![BU of 7f5g by Molmil](/molmil-images/mine/7f5g) | The crystal structure of RBD-Nanobody complex, DL4 (SA4) | Descriptor: | ACETATE ION, GLYCEROL, Nanobody DL4, ... | Authors: | Li, T, Lai, Y, Zhou, Y, Tan, J, Li, D. | Deposit date: | 2021-06-22 | Release date: | 2022-05-25 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Isolation, characterization, and structure-based engineering of a neutralizing nanobody against SARS-CoV-2. Int.J.Biol.Macromol., 209, 2022
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7B76
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![BU of 7b76 by Molmil](/molmil-images/mine/7b76) | Crystal structure of the effector AvrLm5-9 from Leptosphaeria maculans | Descriptor: | Avirulence protein LmJ1, IODIDE ION | Authors: | Lazar, N, Mesarich, C, Petit-Houdenot, Y, Talbi, N, Li de la Sierra-Gallay, I, Zelie, E, Blondeau, K, Gracy, J, Ollivier, B, van de Wouw, A, Balesdent, M.H, Idnurm, A, van Tilbeurgh, H, Fudal, I. | Deposit date: | 2020-12-09 | Release date: | 2022-01-12 | Last modified: | 2023-03-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | A new family of structurally conserved fungal effectors displays epistatic interactions with plant resistance proteins. Plos Pathog., 18, 2022
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