5JW2
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![BU of 5jw2 by Molmil](/molmil-images/mine/5jw2) | Crystal structure of mithramycin analogue MTM SA-Phe in complex with a 10-mer DNA AGGGATCCCT | Descriptor: | DNA (5'-D(*AP*GP*GP*GP*AP*TP*CP*CP*CP*T)-3'), Plicamycin, mithramycin analogue MTM SA-Phe, ... | Authors: | Hou, C, Rohr, J, Tsodikov, O.V. | Deposit date: | 2016-05-11 | Release date: | 2016-09-14 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1. Nucleic Acids Res., 44, 2016
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5JW0
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![BU of 5jw0 by Molmil](/molmil-images/mine/5jw0) | Crystal structure of mithramycin analogue MTM SA-Phe in complex with a 10-mer DNA AGGGTACCCT | Descriptor: | DNA (5'-D(P*AP*GP*GP*GP*TP*AP*CP*CP*CP*T)-3'), Plicamycin, mithramycin analogue MTM SA-Phe, ... | Authors: | Hou, C, Rohr, J, Tsodikov, O.V. | Deposit date: | 2016-05-11 | Release date: | 2016-09-14 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1. Nucleic Acids Res., 44, 2016
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7JSL
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![BU of 7jsl by Molmil](/molmil-images/mine/7jsl) | |
7JSA
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![BU of 7jsa by Molmil](/molmil-images/mine/7jsa) | |
5E8G
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![BU of 5e8g by Molmil](/molmil-images/mine/5e8g) | |
5U9N
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![BU of 5u9n by Molmil](/molmil-images/mine/5u9n) | Second Bromodomain of cdg4_1340 from Cryptosporidium parvum, complexed with bromosporine | Descriptor: | Bromo domain containing protein, Bromosporine, SULFATE ION | Authors: | Hou, C.F.D, Lin, Y.H, Loppnau, P, Hutchinson, A, Dong, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Hui, R, Walker, J.R, Structural Genomics Consortium (SGC) | Deposit date: | 2016-12-16 | Release date: | 2017-01-18 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Second Bromodomain of cdg4_1340 from Cryptosporidium parvum, complexed with bromosporine To be published
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5VS7
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![BU of 5vs7 by Molmil](/molmil-images/mine/5vs7) | Bromodomain of PF3D7_1475600 from Plasmodium falciparum complexed with peptide H4K5ac | Descriptor: | Bromodomain protein, putative, CHLORIDE ION, ... | Authors: | Hou, C.F.D, Loppnau, P, Dong, A, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Hui, R, Walker, J.R, Structural Genomics Consortium (SGC) | Deposit date: | 2017-05-11 | Release date: | 2017-05-31 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Bromodomain of PF3D7_1475600 from Plasmodium falciparum complexed with peptide H4K5ac To be published
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4Z2Y
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![BU of 4z2y by Molmil](/molmil-images/mine/4z2y) | Crystal structure of methyltransferase CalO6 | Descriptor: | CalO6, MERCURY (II) ION | Authors: | Hou, C, Garneau-Tsodikova, S, Tsodikov, O.V. | Deposit date: | 2015-03-30 | Release date: | 2015-07-22 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Crystal structure of O-methyltransferase CalO6 from the calicheamicin biosynthetic pathway: a case of challenging structure determination at low resolution. Bmc Struct.Biol., 15, 2015
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5W34
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![BU of 5w34 by Molmil](/molmil-images/mine/5w34) | |
5W33
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![BU of 5w33 by Molmil](/molmil-images/mine/5w33) | |
4P62
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3LCW
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![BU of 3lcw by Molmil](/molmil-images/mine/3lcw) | L-KDO aldolase complexed with hydroxypyruvate | Descriptor: | 3-HYDROXYPYRUVIC ACID, N-acetylneuraminate lyase, SULFATE ION | Authors: | Chou, C.-Y, Wang, A.H.-J, Ko, T.-P. | Deposit date: | 2010-01-12 | Release date: | 2011-01-19 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Modulation of substrate specificities of D-sialic acid aldolase through single mutations of Val251 To be Published
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8J25
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![BU of 8j25 by Molmil](/molmil-images/mine/8j25) | Crystal structure of PML B-box2 mutant | Descriptor: | Maltose/maltodextrin-binding periplasmic protein,Protein PML, ZINC ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Zhou, C, Zang, N, Zhang, J. | Deposit date: | 2023-04-14 | Release date: | 2023-09-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structural Basis of PML-RARA Oncoprotein Targeting by Arsenic Unravels a Cysteine Rheostat Controlling PML Body Assembly and Function. Cancer Discov, 13, 2023
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7CH6
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![BU of 7ch6 by Molmil](/molmil-images/mine/7ch6) | Cryo-EM structure of E.coli MlaFEB with AMPPNP | Descriptor: | Lipid asymmetry maintenance ABC transporter permease subunit MlaE, Lipid asymmetry maintenance protein MlaB, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Zhou, C, Shi, H, Zhang, M, Huang, Y. | Deposit date: | 2020-07-05 | Release date: | 2021-08-04 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural Insight into Phospholipid Transport by the MlaFEBD Complex from P. aeruginosa. J.Mol.Biol., 433, 2021
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8J2P
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![BU of 8j2p by Molmil](/molmil-images/mine/8j2p) | Crystal structure of PML B-box2 | Descriptor: | Maltose/maltodextrin-binding periplasmic protein,Protein PML, ZINC ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | Authors: | Zhou, C, Zang, N, Zhang, J. | Deposit date: | 2023-04-15 | Release date: | 2023-09-20 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Structural Basis of PML-RARA Oncoprotein Targeting by Arsenic Unravels a Cysteine Rheostat Controlling PML Body Assembly and Function. Cancer Discov, 13, 2023
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7CH7
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![BU of 7ch7 by Molmil](/molmil-images/mine/7ch7) | Cryo-EM structure of E.coli MlaFEB | Descriptor: | Lipid asymmetry maintenance ABC transporter permease subunit MlaE, Lipid asymmetry maintenance protein MlaB, Phospholipid ABC transporter ATP-binding protein MlaF | Authors: | Zhou, C, Shi, H, Huang, Y. | Deposit date: | 2020-07-05 | Release date: | 2021-05-19 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural Insight into Phospholipid Transport by the MlaFEBD Complex from P. aeruginosa. J.Mol.Biol., 433, 2021
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7CHA
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![BU of 7cha by Molmil](/molmil-images/mine/7cha) | Cryo-EM structure of P.aeruginosa MlaFEBD with AMPPNP | Descriptor: | 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, MlaD domain-containing protein, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | Authors: | Zhou, C, Shi, H, Zhang, M, Huang, Y. | Deposit date: | 2020-07-05 | Release date: | 2021-05-19 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural Insight into Phospholipid Transport by the MlaFEBD Complex from P. aeruginosa. J.Mol.Biol., 433, 2021
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7CH9
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![BU of 7ch9 by Molmil](/molmil-images/mine/7ch9) | Cryo-EM structure of P.aeruginosa MlaFEBD | Descriptor: | 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, MlaD domain-containing protein, Probable ATP-binding component of ABC transporter, ... | Authors: | Zhou, C, Shi, H, Zhang, M, Huang, Y. | Deposit date: | 2020-07-05 | Release date: | 2021-10-06 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural Insight into Phospholipid Transport by the MlaFEBD Complex from P. aeruginosa. J.Mol.Biol., 433, 2021
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7CH8
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![BU of 7ch8 by Molmil](/molmil-images/mine/7ch8) | Cryo-EM structure of P.aeruginosa MlaFEBD with ADP-V | Descriptor: | 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, ADP METAVANADATE, MAGNESIUM ION, ... | Authors: | Zhou, C, Shi, H, Zhang, M, Huang, Y. | Deposit date: | 2020-07-05 | Release date: | 2021-10-06 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural Insight into Phospholipid Transport by the MlaFEBD Complex from P. aeruginosa. J.Mol.Biol., 433, 2021
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8H8Y
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![BU of 8h8y by Molmil](/molmil-images/mine/8h8y) | Crystal structure of AbHheG from Acidimicrobiia bacterium | Descriptor: | GLYCEROL, alpha/beta hydrolase | Authors: | Zhou, C.H, Chen, X, Han, X, Liu, W.D, Wu, Q.Q, Zhu, D.M, Ma, Y.H. | Deposit date: | 2022-10-24 | Release date: | 2023-08-02 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Flipping the Substrate Creates a Highly Selective Halohydrin Dehalogenase for the Synthesis of Chiral 4-Aryl-2-oxazolidinones from Readily Available Epoxides Acs Catalysis, 13, 2023
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8HQP
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![BU of 8hqp by Molmil](/molmil-images/mine/8hqp) | Crystal structure of AbHheG mutant from Acidimicrobiia bacterium | Descriptor: | AbHheG_m | Authors: | Zhou, C.H, Chen, X, Han, X, Liu, W.D, Wu, Q.Q, Zhu, D.M, Ma, Y.H. | Deposit date: | 2022-12-13 | Release date: | 2023-08-02 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.62 Å) | Cite: | Flipping the Substrate Creates a Highly Selective Halohydrin Dehalogenase for the Synthesis of Chiral 4-Aryl-2-oxazolidinones from Readily Available Epoxides Acs Catalysis, 13, 2023
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6S3W
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![BU of 6s3w by Molmil](/molmil-images/mine/6s3w) | Solution NMR Structure of TolAIII Bound to a Peptide Derived from the N-terminus of TolB | Descriptor: | Cell envelope integrity/translocation protein TolA, TolBp | Authors: | Kleanthous, C, Redfield, C, Rajasekar, K, Holmes, P. | Deposit date: | 2019-06-26 | Release date: | 2020-03-25 | Last modified: | 2024-07-03 | Method: | SOLUTION NMR | Cite: | The lipoprotein Pal stabilises the bacterial outer membrane during constriction by a mobilisation-and-capture mechanism. Nat Commun, 11, 2020
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5EAX
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![BU of 5eax by Molmil](/molmil-images/mine/5eax) | Crystal structure of Dna2 in complex with an ssDNA | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), DNA replication ATP-dependent helicase/nuclease DNA2, ... | Authors: | Zhou, C, Pourmal, S, Pavletich, N.P. | Deposit date: | 2015-10-17 | Release date: | 2015-11-18 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Dna2 nuclease-helicase structure, mechanism and regulation by Rpa. Elife, 4, 2015
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5EAN
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![BU of 5ean by Molmil](/molmil-images/mine/5ean) | Crystal structure of Dna2 in complex with a 5' overhang DNA | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, DNA (5'-D(P*AP*CP*TP*CP*TP*GP*CP*CP*AP*AP*GP*AP*GP*GP*A)-3'), ... | Authors: | Zhou, C, Pourmal, S, Pavletich, N.P. | Deposit date: | 2015-10-16 | Release date: | 2015-11-18 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.36 Å) | Cite: | Dna2 nuclease-helicase structure, mechanism and regulation by Rpa. Elife, 4, 2015
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8FUK
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![BU of 8fuk by Molmil](/molmil-images/mine/8fuk) | |