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PDB: 1 results

4JOA
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Crystal Structure of Human Anaplastic Lymphoma Kinase in complex with 7-azaindole based inhibitor
Descriptor: 3-[1-(2,5-difluorobenzyl)-1H-pyrazol-4-yl]-5-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine, ALK tyrosine kinase receptor
Authors:Hosahalli, S, Krishnamurthy, N.R, Lakshminarasimhan, A.
Deposit date:2013-03-18
Release date:2013-07-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Discovery of 7-azaindole based anaplastic lymphoma kinase (ALK) inhibitors: wild type and mutant (L1196M) active compounds with unique binding mode
Bioorg.Med.Chem.Lett., 23, 2013

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