Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 16 件
7CGW
DownloadVisualize
BU of 7cgw by Molmil
Complex structure of PD-1 and tislelizumab Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of tislelizumab Fab, Light chain of tislelizumab Fab, ...
著者Hong, Y, Feng, Y.C, Liu, Y.
登録日2020-07-02
公開日2021-04-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Tislelizumab uniquely binds to the CC' loop of PD-1 with slow-dissociated rate and complete PD-L1 blockage.
Febs Open Bio, 11, 2021
6K98
DownloadVisualize
BU of 6k98 by Molmil
Substrates promiscuity of xyloglucanases and endoglucanases of glycoside hydrolase 12 family
分子名称: GH12 beta-1, 4-endoglucanase
著者Hong, Y, Tao, T, Pengjun, S, Jiaming, C, Xiaoyu, W, Chen, H, yingguo, B, Bin, Y.
登録日2019-06-14
公開日2020-06-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.032 Å)
主引用文献Substrates promiscuity of xyloglucanases and endoglucanases of glycoside hydrolase 12 family
To Be Published
6K9D
DownloadVisualize
BU of 6k9d by Molmil
glycoside hydrolase family 12 (GH12) englucanase
分子名称: GH12 beta-1, 4-endoglucanase
著者Hong, Y, Tao, T, Pengjun, S, Jiaming, C, Xiaoyu, W, Chen, H, Yingguo, B, Bin, Y.
登録日2019-06-14
公開日2020-06-17
実験手法X-RAY DIFFRACTION (1.505 Å)
主引用文献Substrates promiscuity of xyloglucanases and endoglucanases of glycoside hydrolase 12 family
To Be Published
6ITS
DownloadVisualize
BU of 6its by Molmil
The citrate-bound trimer of chemoreceptor MCP2201 ligand binding domain
分子名称: CITRIC ACID, Methyl-accepting chemotaxis sensory transducer
著者Hong, Y, Li, D.F.
登録日2018-11-26
公開日2018-12-26
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献The ligand-binding domain of a chemoreceptor from Comamonas testosteroni has a previously unknown homotrimeric structure.
Mol.Microbiol., 112, 2019
5XUA
DownloadVisualize
BU of 5xua by Molmil
The ligand-free dimer of chemoreceptor MCP2201 ligand binding domain
分子名称: Methyl-accepting chemotaxis sensory transducer
著者Hong, Y, Li, D.F, Wang, D.C.
登録日2017-06-23
公開日2018-06-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The ligand-binding domain of a chemoreceptor from Comamonas testosteroni has a previously unknown homotrimeric structure.
Mol.Microbiol., 2019
5XUB
DownloadVisualize
BU of 5xub by Molmil
The citrate-bound trimer of chemoreceptor MCP2201 ligand binding domain
分子名称: CITRIC ACID, Methyl-accepting chemotaxis sensory transducer
著者Hong, Y, Li, D.F, Wang, D.C.
登録日2017-06-23
公開日2018-06-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献The ligand-binding domain of a chemoreceptor from Comamonas testosteroni has a previously unknown homotrimeric structure.
Mol.Microbiol., 2019
7WRM
DownloadVisualize
BU of 7wrm by Molmil
The malate-bound dimer of chemoreceptor MCP2201 ligand binding domain
分子名称: (2S)-2-hydroxybutanedioic acid, Methyl-accepting chemotaxis sensory transducer
著者Hong, Y, Guo, L, Li, D.F.
登録日2022-01-27
公開日2023-01-04
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The repellent response to malate mediated by chemoreceptor MCP2201 in Comamonas testosteroni CNB-1
to be published
1EQX
DownloadVisualize
BU of 1eqx by Molmil
SOLUTION STRUCTURE DETERMINATION AND MUTATIONAL ANALYSIS OF THE PAPILLOMAVIRUS E6-INTERACTING PEPTIDE OF E6AP
分子名称: PAPILLOMAVIRUS E6-ASSOCIATED PROTEIN
著者Be, X, Hong, Y, Androphy, E.J, Chen, J.J, Baleja, J.D.
登録日2000-04-06
公開日2001-02-28
最終更新日2022-02-16
実験手法SOLUTION NMR
主引用文献Solution structure determination and mutational analysis of the papillomavirus E6 interacting peptide of E6AP.
Biochemistry, 40, 2001
6J6M
DownloadVisualize
BU of 6j6m by Molmil
Co-crystal structure of BTK kinase domain with Zanubrutinib
分子名称: (7S)-2-(4-phenoxyphenyl)-7-(1-propanoylpiperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide, IMIDAZOLE, Tyrosine-protein kinase BTK
著者Zhou, X, Hong, Y.
登録日2019-01-15
公開日2019-10-23
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Discovery of Zanubrutinib (BGB-3111), a Novel, Potent, and Selective Covalent Inhibitor of Bruton's Tyrosine Kinase.
J.Med.Chem., 62, 2019
5UJV
DownloadVisualize
BU of 5ujv by Molmil
Crystal structure of FePYR1 in complex with abscisic acid
分子名称: (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, PYR1
著者Ren, Z, Wang, Z, Zhou, X.E, Hong, Y, Cao, M, Chan, Z, Liu, X, Shi, H, Xu, H.E, Zhu, J.-K.
登録日2017-01-19
公開日2017-11-08
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure determination and activity manipulation of the turfgrass ABA receptor FePYR1.
Sci Rep, 7, 2017
8HOH
DownloadVisualize
BU of 8hoh by Molmil
Crystal structure of Bcl-2 G101V in complex with sonrotoclax
分子名称: Apoptosis regulator Bcl-2, ~{N}-[4-[(4-methyl-4-oxidanyl-cyclohexyl)methylamino]-3-nitro-phenyl]sulfonyl-4-[2-[(2~{S})-2-(2-propan-2-ylphenyl)pyrrolidin-1-yl]-7-azaspiro[3.5]nonan-7-yl]-2-(1~{H}-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide
著者Liu, J, Xu, M, Feng, Y, Hong, Y, Liu, Y.
登録日2022-12-10
公開日2024-01-17
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Sonrotoclax overcomes BCL2 G101V mutation-induced venetoclax resistance in preclinical models of hematologic malignancy.
Blood, 143, 2024
8HOG
DownloadVisualize
BU of 8hog by Molmil
Crystal structure of Bcl-2 in complex with sonrotoclax
分子名称: Apoptosis regulator Bcl-2, ~{N}-[4-[(4-methyl-4-oxidanyl-cyclohexyl)methylamino]-3-nitro-phenyl]sulfonyl-4-[2-[(2~{S})-2-(2-propan-2-ylphenyl)pyrrolidin-1-yl]-7-azaspiro[3.5]nonan-7-yl]-2-(1~{H}-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide
著者Liu, J, Xu, M, Feng, Y, Hong, Y, Liu, Y.
登録日2022-12-10
公開日2024-01-17
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Sonrotoclax overcomes BCL2 G101V mutation-induced venetoclax resistance in preclinical models of hematologic malignancy.
Blood, 143, 2024
8HOI
DownloadVisualize
BU of 8hoi by Molmil
Crystal structure of Bcl-2 D103Y in complex with sonrotoclax
分子名称: Apoptosis regulator Bcl-2, FORMIC ACID, ~{N}-[4-[(4-methyl-4-oxidanyl-cyclohexyl)methylamino]-3-nitro-phenyl]sulfonyl-4-[2-[(2~{S})-2-(2-propan-2-ylphenyl)pyrrolidin-1-yl]-7-azaspiro[3.5]nonan-7-yl]-2-(1~{H}-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide
著者Liu, J, Xu, M, Feng, Y, Hong, Y, Liu, Y.
登録日2022-12-10
公開日2024-01-17
最終更新日2024-05-15
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Sonrotoclax overcomes BCL2 G101V mutation-induced venetoclax resistance in preclinical models of hematologic malignancy.
Blood, 143, 2024
7CMW
DownloadVisualize
BU of 7cmw by Molmil
Complex structure of PARP1 catalytic domain with pamiparib
分子名称: (2R)-14-fluoro-2-methyl-6,9,10,19-tetrazapentacyclo[14.2.1.02,6.08,18.012,17]nonadeca-1(18),8,12(17),13,15-pentaen-11-one, GLYCEROL, Poly [ADP-ribose] polymerase 1
著者Feng, Y.C, Peng, H, Hong, Y, Liu, Y.
登録日2020-07-29
公開日2020-12-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Discovery of Pamiparib (BGB-290), a Potent and Selective Poly (ADP-ribose) Polymerase (PARP) Inhibitor in Clinical Development.
J.Med.Chem., 63, 2020
2XIR
DownloadVisualize
BU of 2xir by Molmil
Crystal structure of the VEGFR2 kinase domain in complex with PF- 00337210 (N,2-dimethyl-6-(7-(2-morpholinoethoxy)quinolin-4-yloxy) benzofuran-3-carboxamide)
分子名称: N,2-DIMETHYL-6-{[7-(2-MORPHOLIN-4-YLETHOXY)QUINOLIN-4-YL]OXY}-1-BENZOFURAN-3-CARBOXAMIDE, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2
著者McTigue, M, Wickersham, J, Pinko, C, Hong, Y, Marrone, T.
登録日2010-06-30
公開日2011-04-13
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Discovery of the Selective Vegfr Inhibitor Pf- 00337210
To be Published
7EAV
DownloadVisualize
BU of 7eav by Molmil
The X-ray crystallographic structure of glycogen debranching enzyme from Sulfolobus solfataricus STB09
分子名称: Glycogen debranching enzyme
著者Li, Z.F, Ban, X.F, Tian, Y.X, Li, C.M, Cheng, L, Hong, Y, Gu, Z.B.
登録日2021-03-08
公開日2022-03-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.803 Å)
主引用文献The X-ray Crystallographic Structure of Debranching Enzyme from Sulfolobus solfataricus STB09
To Be Published

219869

件を2024-05-15に公開中

PDB statisticsPDBj update infoContact PDBjnumon