4H2K
| Crystal structure of the catalytic domain of succinyl-diaminopimelate desuccinylase from Haemophilus influenzae | Descriptor: | Succinyl-diaminopimelate desuccinylase, ZINC ION | Authors: | Nocek, B, Jedrzejczak, R, Makowska-Grzyska, M, Starus, A, Holz, R, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2012-09-12 | Release date: | 2012-11-21 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.84 Å) | Cite: | The dimerization domain in DapE enzymes is required for catalysis. Plos One, 9, 2014
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9D6M
| Nitrile hydratase BR157K mutant | Descriptor: | Cobalt-containing nitrile hydratase subunit alpha, Cobalt-containing nitrile hydratase subunit beta | Authors: | Miller, C.G, Holz, R.C, Liu, D, Kaley, N. | Deposit date: | 2024-08-15 | Release date: | 2024-08-28 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Role of second-sphere arginine residues in metal binding and metallocentre assembly in nitrile hydratases. J Inorg Biochem, 256, 2024
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9D65
| Nitrile hydratase BR52A mutant | Descriptor: | Cobalt-containing nitrile hydratase subunit alpha, Cobalt-containing nitrile hydratase subunit beta | Authors: | Miller, C.G, Holz, R.C, Liu, D, Kaley, N. | Deposit date: | 2024-08-14 | Release date: | 2024-08-28 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Role of second-sphere arginine residues in metal binding and metallocentre assembly in nitrile hydratases. J Inorg Biochem, 256, 2024
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9D6K
| Nitrile hydratase BR157A mutant | Descriptor: | Cobalt-containing nitrile hydratase subunit alpha, Cobalt-containing nitrile hydratase subunit beta, OXYGEN ATOM | Authors: | Miller, C.G, Holz, R.C, Liu, D, Kaley, N. | Deposit date: | 2024-08-15 | Release date: | 2024-09-25 | Method: | X-RAY DIFFRACTION (1.29 Å) | Cite: | Role of second-sphere arginine residues in metal binding and metallocentre assembly in nitrile hydratases. J Inorg Biochem, 256, 2024
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9D6J
| Nitrile hydratase BR52K mutant | Descriptor: | Cobalt-containing nitrile hydratase subunit alpha, Cobalt-containing nitrile hydratase subunit beta | Authors: | Miller, C.G, Holz, R.C, Liu, D, Kaley, N. | Deposit date: | 2024-08-15 | Release date: | 2024-08-28 | Method: | X-RAY DIFFRACTION (1.47 Å) | Cite: | Role of second-sphere arginine residues in metal binding and metallocentre assembly in nitrile hydratases. J Inorg Biochem, 256, 2024
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3IC1
| Crystal structure of zinc-bound succinyl-diaminopimelate desuccinylase from Haemophilus influenzae | Descriptor: | GLYCEROL, SULFATE ION, Succinyl-diaminopimelate desuccinylase, ... | Authors: | Nocek, B.P, Gillner, D.M, Holz, R.C, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-07-17 | Release date: | 2009-09-22 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural basis for catalysis by the mono- and dimetalated forms of the dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase. J.Mol.Biol., 397, 2010
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3ISZ
| Crystal structure of mono-zinc form of succinyl-diaminopimelate desuccinylase from Haemophilus influenzae | Descriptor: | SULFATE ION, Succinyl-diaminopimelate desuccinylase, ZINC ION | Authors: | Nocek, B.P, Gillner, D.M, Holz, R.C, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2009-08-27 | Release date: | 2009-11-10 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural basis for catalysis by the mono- and dimetalated forms of the dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase. J.Mol.Biol., 397, 2010
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4ZGJ
| Double Mutant H80A/H81A of Fe-Type Nitrile Hydratase from Comamonas testosteroni Ni1 | Descriptor: | FE (III) ION, Nitrile hydratase alpha subunit, Nitrile hydratase beta subunit | Authors: | Wu, R, Martinez, S, Holz, R, Liu, D. | Deposit date: | 2015-04-23 | Release date: | 2015-07-01 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Analyzing the catalytic role of active site residues in the Fe-type nitrile hydratase from Comamonas testosteroni Ni1. J.Biol.Inorg.Chem., 20, 2015
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4ZGD
| Mutant R157A of Fe-Type Nitrile Hydratase from Comamonas testosteroni Ni1 | Descriptor: | FE (III) ION, Nitrile hydratase alpha subunit, Nitrile hydratase beta subunit | Authors: | Wu, R, Martinez, S, Holz, R, Liu, D. | Deposit date: | 2015-04-22 | Release date: | 2015-07-01 | Last modified: | 2015-07-08 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Analyzing the catalytic role of active site residues in the Fe-type nitrile hydratase from Comamonas testosteroni Ni1. J.Biol.Inorg.Chem., 20, 2015
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4ZGE
| Double Mutant H80W/H81W of Fe-Type Nitrile Hydratase from Comamonas testosteroni Ni1 | Descriptor: | FE (III) ION, Nitrile hydratase alpha subunit, Nitrile hydratase beta subunit | Authors: | Wu, R, Martinez, S, Holz, R, Liu, D. | Deposit date: | 2015-04-22 | Release date: | 2015-07-01 | Last modified: | 2015-07-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Analyzing the catalytic role of active site residues in the Fe-type nitrile hydratase from Comamonas testosteroni Ni1. J.Biol.Inorg.Chem., 20, 2015
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1LOK
| The 1.20 Angstrom Resolution Crystal Structure of the Aminopeptidase from Aeromonas proteolytica Complexed with Tris: A Tale of Buffer Inhibition | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bacterial leucyl aminopeptidase, SODIUM ION, ... | Authors: | Desmarais, W.T, Bienvenue, D.L, Bzymek, K.P, Holz, R.C, Petsko, G.A, Ringe, D. | Deposit date: | 2002-05-06 | Release date: | 2002-11-27 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | The 1.20 Angstrom Resolution Crystal Structure of the Aminopeptidase from Aeromonas proteolytica Complexed with Tris A tale of Buffer Inhibition Structure, 10, 2002
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4FM4
| Wild Type Fe-type Nitrile Hydratase from Comamonas testosteroni Ni1 | Descriptor: | FE (III) ION, Nitrile hydratase alpha subunit, Nitrile hydratase beta subunit, ... | Authors: | Kuhn, M.L, Martinez, S, Gumataotao, N, Bornscheuer, U, Liu, D, Holz, R.C. | Deposit date: | 2012-06-15 | Release date: | 2012-08-22 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.384 Å) | Cite: | The Fe-type nitrile hydratase from Comamonas testosteroni Ni1 does not require an activator accessory protein for expression in Escherichia coli. Biochem.Biophys.Res.Commun., 424, 2012
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1WKM
| THE PRODUCT BOUND FORM OF THE MN(II)LOADED METHIONINE AMINOPEPTIDASE FROM HYPERTHERMOPHILE PYROCOCCUS FURIOSUS | Descriptor: | MANGANESE (II) ION, METHIONINE, Methionine aminopeptidase | Authors: | Copik, A.J, Nocek, B.P, Jang, S.B, Swierczek, S.I, Ruebush, S, Meng, L, D'souza, V.M, Peters, J.W, Bennett, B, Holz, R.C. | Deposit date: | 2004-06-01 | Release date: | 2005-02-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | EPR and X-ray crystallographic characterization of the product-bound form of the MnII-loaded methionyl aminopeptidase from Pyrococcus furiosus Biochemistry, 44, 2005
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1FT7
| AAP COMPLEXED WITH L-LEUCINEPHOSPHONIC ACID | Descriptor: | BACTERIAL LEUCYL AMINOPEPTIDASE, LEUCINE PHOSPHONIC ACID, POTASSIUM ION, ... | Authors: | Stamper, C, Bennett, B, Holz, R, Petsko, G, Ringe, D. | Deposit date: | 2000-09-11 | Release date: | 2000-10-04 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Inhibition of the aminopeptidase from Aeromonas proteolytica by L-leucinephosphonic acid. Spectroscopic and crystallographic characterization of the transition state of peptide hydrolysis. Biochemistry, 40, 2001
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2ANP
| Functional Glutamate 151 to Histidine mutant of the aminopeptidase from Aeromonas Proteolytica. | Descriptor: | SODIUM ION, ZINC ION, leucyl aminopeptidase | Authors: | Bzymek, K.P, Moulin, A, Swierczek, S.I, Ringe, D, Petsko, G.A, Holz, R.C. | Deposit date: | 2005-08-11 | Release date: | 2005-10-04 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Kinetic, Spectroscopic, and X-ray Crystallographic Characterization of the Functional E151H Aminopeptidase from Aeromonas proteolytica. Biochemistry, 44, 2005
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4PQA
| Crystal Structure of succinyl-diaminopimelate desuccinylase from Neisseria meningitidis MC58 in complex with the Inhibitor Captopril | Descriptor: | L-CAPTOPRIL, SULFATE ION, Succinyl-diaminopimelate desuccinylase, ... | Authors: | Nocek, B, Starus, A, Holz, R, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2014-03-01 | Release date: | 2014-04-30 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Inhibition of the dapE-Encoded N-Succinyl-L,L-diaminopimelic Acid Desuccinylase from Neisseria meningitidis by L-Captopril. Biochemistry, 54, 2015
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2PRQ
| X-ray crystallographic characterization of the Co(II)-substituted Tris-bound form of the aminopeptidase from Aeromonas proteolytica | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bacterial leucyl aminopeptidase, COBALT (II) ION | Authors: | Munih, P, Moulin, A, Stamper, C.C, Bennet, B, Ringe, D, Petsko, G.A, Holz, R.C. | Deposit date: | 2007-05-04 | Release date: | 2007-06-12 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | X-ray crystallographic characterization of the Co(II)-substituted Tris-bound form of the aminopeptidase from Aeromonas proteolytica. J.Inorg.Biochem., 101, 2007
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4PPZ
| Crystal structure of zinc-bound succinyl-diaminopimelate desuccinylase from Neisseria meningitidis MC58 | Descriptor: | PHOSPHATE ION, Succinyl-diaminopimelate desuccinylase, ZINC ION | Authors: | Nocek, B, Holz, R, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2014-02-27 | Release date: | 2014-03-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Inhibition of the dapE-Encoded N-Succinyl-L,L-diaminopimelic Acid Desuccinylase from Neisseria meningitidis by L-Captopril. Biochemistry, 54, 2015
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1CP6
| 1-BUTANEBORONIC ACID BINDING TO AEROMONAS PROTEOLYTICA AMINOPEPTIDASE | Descriptor: | 1-BUTANE BORONIC ACID, PROTEIN (AMINOPEPTIDASE), ZINC ION | Authors: | Depaola, C.C, Bennett, B, Holz, R.C, Ringe, D, Petsko, G.A. | Deposit date: | 1999-06-08 | Release date: | 1999-06-17 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | 1-Butaneboronic acid binding to Aeromonas proteolytica aminopeptidase: a case of arrested development. Biochemistry, 38, 1999
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1RTQ
| The 0.95 Angstrom Resolution Crystal Structure of the Aminopeptidase from Aeromonas proteolytica | Descriptor: | Bacterial leucyl aminopeptidase, SODIUM ION, THIOCYANATE ION, ... | Authors: | Desmarais, W, Bienvenue, D.L, Krzysztof, B.P, Holz, R.C, Petsko, G.A, Ringe, D. | Deposit date: | 2003-12-10 | Release date: | 2004-02-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (0.95 Å) | Cite: | The high-resolution structures of the neutral and the low pH crystals of aminopeptidase from Aeromonas proteolytica. J.Biol.Inorg.Chem., 11, 2006
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1TXR
| X-ray crystal structure of bestatin bound to AAP | Descriptor: | 2-(3-AMINO-2-HYDROXY-4-PHENYL-BUTYRYLAMINO)-4-METHYL-PENTANOIC ACID, Bacterial leucyl aminopeptidase, ZINC ION | Authors: | Stamper, C.C, Holz, R.C, Ringe, D, Petsko, G.A. | Deposit date: | 2004-07-06 | Release date: | 2004-07-20 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Spectroscopic and X-ray Crystallographic Characterization of Bestatin Bound to the Aminopeptidase from Aeromonas (Vibrio) proteolytica. Biochemistry, 43, 2004
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4O23
| Crystal structure of mono-zinc form of succinyl diaminopimelate desuccinylase from Neisseria meningitidis MC58 | Descriptor: | SULFATE ION, Succinyl-diaminopimelate desuccinylase, ZINC ION | Authors: | Nocek, B, Holz, R, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-12-16 | Release date: | 2014-01-15 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Inhibition of the dapE-Encoded N-Succinyl-L,L-diaminopimelic Acid Desuccinylase from Neisseria meningitidis by L-Captopril. Biochemistry, 54, 2015
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1VRS
| Crystal structure of the disulfide-linked complex between the N-terminal and C-terminal domain of the electron transfer catalyst DsbD | Descriptor: | Thiol:disulfide interchange protein dsbD | Authors: | Rozhkova, A, Stirnimann, C.U, Frei, P, Grauschopf, U, Brunisholz, R, Gruetter, M.G, Capitani, G, Glockshuber, R. | Deposit date: | 2005-06-17 | Release date: | 2005-07-12 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structural basis and kinetics of inter- and intramolecular disulfide exchange in the redox catalyst DsbD Embo J., 23, 2004
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