4DK3
| Structure of Editosome protein | 分子名称: | RNA-editing complex protein MP81, single domain antibody VHH | 著者 | Park, Y.-J, Hol, W. | 登録日 | 2012-02-03 | 公開日 | 2012-07-04 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | The structure of the C-terminal domain of the largest editosome interaction protein and its role in promoting RNA binding by RNA-editing ligase L2. Nucleic Acids Res., 40, 2012
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4DKA
| Structure of Editosome protein | 分子名称: | RNA-editing complex protein MP81, SODIUM ION, single domain antibody VHH | 著者 | Park, Y.-J, Hol, W. | 登録日 | 2012-02-03 | 公開日 | 2012-07-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | 主引用文献 | The structure of the C-terminal domain of the largest editosome interaction protein and its role in promoting RNA binding by RNA-editing ligase L2. Nucleic Acids Res., 40, 2012
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4DNI
| Structure of Editosome protein | 分子名称: | Fusion protein of RNA-editing complex proteins MP42 and MP18 | 著者 | Park, Y.-J, Hol, W. | 登録日 | 2012-02-08 | 公開日 | 2012-12-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Explorations of linked editosome domains leading to the discovery of motifs defining conserved pockets in editosome OB-folds. J.Struct.Biol., 180, 2012
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4DK6
| Structure of Editosome protein | 分子名称: | RNA-editing complex protein MP81, single domain antibody VHH | 著者 | Park, Y.-J, Hol, W. | 登録日 | 2012-02-03 | 公開日 | 2012-07-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | The structure of the C-terminal domain of the largest editosome interaction protein and its role in promoting RNA binding by RNA-editing ligase L2. Nucleic Acids Res., 40, 2012
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3SOL
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2BP2
| THE STRUCTURE OF BOVINE PANCREATIC PROPHOSPHOLIPASE A2 AT 3.0 ANGSTROMS RESOLUTION | 分子名称: | PHOSPHOLIPASE A2 | 著者 | Dijkstra, B.W, Vannes, G.J.H, Kalk, K.H, Brandenburg, N.P, Hol, W.G.J, Drenth, J. | 登録日 | 1981-06-05 | 公開日 | 1981-07-16 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The Structure of Bovine Pancreatic Prophospholipase A2 at 3.0 Angstroms Resolution Acta Crystallogr.,Sect.B, 38, 1982
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2ISY
| Crystal structure of the nickel-activated two-domain iron-dependent regulator (IdeR) | 分子名称: | Iron-dependent repressor ideR, NICKEL (II) ION, PHOSPHATE ION | 著者 | Wisedchaisri, G, Chou, C.J, Wu, M, Roach, C, Rice, A.E, Holmes, R.K, Beeson, C, Hol, W.G. | 登録日 | 2006-10-18 | 公開日 | 2007-02-13 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.955 Å) | 主引用文献 | Crystal structures, metal activation, and DNA-binding properties of two-domain IdeR from Mycobacterium tuberculosis Biochemistry, 46, 2007
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1LPF
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3LAD
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1TQX
| Crystal Structure of Pfal009167 A Putative D-Ribulose 5-Phosphate 3-Epimerase from P.falciparum | 分子名称: | D-ribulose-5-phosphate 3-epimerase, putative, SULFATE ION, ... | 著者 | Caruthers, J, Bosch, J, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) | 登録日 | 2004-06-18 | 公開日 | 2004-12-21 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of a ribulose 5-phosphate 3-epimerase from Plasmodium falciparum. Proteins, 62, 2006
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1A5C
| FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE FROM PLASMODIUM FALCIPARUM | 分子名称: | FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE | 著者 | Kim, H, Certa, U, Dobeli, H, Jakob, P, Hol, W.G.J. | 登録日 | 1998-02-13 | 公開日 | 1998-06-10 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of fructose-1,6-bisphosphate aldolase from the human malaria parasite Plasmodium falciparum. Biochemistry, 37, 1998
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1A31
| HUMAN RECONSTITUTED DNA TOPOISOMERASE I IN COVALENT COMPLEX WITH A 22 BASE PAIR DNA DUPLEX | 分子名称: | DNA (5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*5IUP*5IU*TP*GP*AP*AP*AP*AP*AP*5IUP*5IUP*5IUP*5IUP*T)-3'), DNA (5'-D(*AP*AP*AP*AP*AP*TP*5IUP*5IUP*5IUP*5IUP*CP*AP*AP*AP*GP*TP*CP*TP*TP*TP*TP*T)-3'), PROTEIN (TOPOISOMERASE I) | 著者 | Redinbo, M.R, Stewart, L, Kuhn, P, Champoux, J.J, Hol, W.G.J. | 登録日 | 1998-01-27 | 公開日 | 1998-08-28 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science, 279, 1998
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1AG1
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1A36
| TOPOISOMERASE I/DNA COMPLEX | 分子名称: | DNA (5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*TP*AP*GP*AP*AP*AP*AP*A P*TP*TP*TP*TP*T)- 3'), DNA (5'-D(*AP*AP*AP*AP*AP*TP*TP*TP*TP*TP*CP*TP*AP*AP*GP*TP*C P*TP*TP*TP*TP*T)- 3'), TOPOISOMERASE I | 著者 | Stewart, L, Redinbo, M.R, Qiu, X, Champoux, J.J, Hol, W.G.J. | 登録日 | 1998-01-29 | 公開日 | 1998-08-12 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A model for the mechanism of human topoisomerase I. Science, 279, 1998
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4MW2
| Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-(3-{[5-chloro-2-hydroxy-3-(prop-2-en-1-yl)benzyl]amino}propyl)-3-thiophen-3-ylurea (Chem 1472) | 分子名称: | 1-(3-{[5-chloro-2-hydroxy-3-(prop-2-en-1-yl)benzyl]amino}propyl)-3-thiophen-3-ylurea, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Koh, C.Y, Kim, J.E, Wetzel, A.B, de van der Schueren, W.J, Shibata, S, Liu, J, Zhang, Z, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. | 登録日 | 2013-09-24 | 公開日 | 2014-04-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness. Plos Negl Trop Dis, 8, 2014
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4MW7
| Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(5-chloro-2-ethoxy-3-iodobenzyl)amino]propyl}-3-thiophen-3-ylurea (Chem 1469) | 分子名称: | 1-{3-[(5-chloro-2-ethoxy-3-iodobenzyl)amino]propyl}-3-thiophen-3-ylurea, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Koh, C.Y, Kim, J.E, Wetzel, A.B, de van der Schueren, W.J, Shibata, S, Liu, J, Zhang, Z, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. | 登録日 | 2013-09-24 | 公開日 | 2014-04-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness. Plos Negl Trop Dis, 8, 2014
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16PK
| PHOSPHOGLYCERATE KINASE FROM TRYPANOSOMA BRUCEI BISUBSTRATE ANALOG | 分子名称: | 1,1,5,5-TETRAFLUOROPHOSPHOPENTYLPHOSPHONIC ACID ADENYLATE ESTER, 3-PHOSPHOGLYCERATE KINASE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | 著者 | Bernstein, B.E, Bressi, J, Blackburn, M, Gelb, M, Hol, W.G.J. | 登録日 | 1998-05-18 | 公開日 | 1998-11-25 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | A bisubstrate analog induces unexpected conformational changes in phosphoglycerate kinase from Trypanosoma brucei. J.Mol.Biol., 279, 1998
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4MW4
| Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-{3-[(5-chloro-2-hydroxy-3-iodobenzyl)amino]propyl}-3-thiophen-3-ylurea (Chem 1473) | 分子名称: | 1-{3-[(5-chloro-2-hydroxy-3-iodobenzyl)amino]propyl}-3-thiophen-3-ylurea, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Koh, C.Y, Kim, J.E, Wetzel, A.B, de van der Schueren, W.J, Shibata, S, Liu, J, Zhang, Z, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. | 登録日 | 2013-09-24 | 公開日 | 2014-04-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness. Plos Negl Trop Dis, 8, 2014
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1BI0
| STRUCTURE OF APO-AND HOLO-DIPHTHERIA TOXIN REPRESSOR | 分子名称: | DIPHTHERIA TOXIN REPRESSOR, SULFATE ION, ZINC ION | 著者 | Pohl, E, Hol, W.G. | 登録日 | 1998-06-21 | 公開日 | 1999-07-22 | 最終更新日 | 2022-12-21 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Motion of the DNA-binding domain with respect to the core of the diphtheria toxin repressor (DtxR) revealed in the crystal structures of apo- and holo-DtxR. J.Biol.Chem., 273, 1998
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2PC4
| Crystal structure of fructose-bisphosphate aldolase from Plasmodium falciparum in complex with TRAP-tail determined at 2.4 angstrom resolution | 分子名称: | Fructose-bisphosphate aldolase, PbTRAP | 著者 | Bosch, J, Buscaglia, C.A, Krumm, B, Cardozo, T, Nussenzweig, V, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP) | 登録日 | 2007-03-29 | 公開日 | 2007-04-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Aldolase provides an unusual binding site for thrombospondin-related anonymous protein in the invasion machinery of the malaria parasite. Proc.Natl.Acad.Sci.Usa, 104, 2007
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2QV8
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4EG1
| Trypanosoma brucei methionyl-tRNA synthetase in complex with substrate Methionine | 分子名称: | GLYCEROL, METHIONINE, Methionyl-tRNA synthetase, ... | 著者 | Koh, C.Y, Kim, J.E, Shibata, S, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. | 登録日 | 2012-03-30 | 公開日 | 2012-09-12 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection. Structure, 20, 2012
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2RET
| The crystal structure of a binary complex of two pseudopilins: EpsI and EpsJ from the Type 2 Secretion System of Vibrio vulnificus | 分子名称: | CHLORIDE ION, EpsJ, Pseudopilin EpsI, ... | 著者 | Yanez, M.E, Korotkov, K.V, Abendroth, J, Hol, W.G.J. | 登録日 | 2007-09-27 | 公開日 | 2008-02-05 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | The crystal structure of a binary complex of two pseudopilins: EpsI and EpsJ from the type 2 secretion system of Vibrio vulnificus. J.Mol.Biol., 375, 2008
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2TEC
| MOLECULAR DYNAMICS REFINEMENT OF A THERMITASE-EGLIN-C COMPLEX AT 1.98 ANGSTROMS RESOLUTION AND COMPARISON OF TWO CRYSTAL FORMS THAT DIFFER IN CALCIUM CONTENT | 分子名称: | CALCIUM ION, EGLIN C, THERMITASE | 著者 | Gros, P, Betzel, C, Dauter, Z, Wilson, K.S, Hol, W.G.J. | 登録日 | 1990-10-26 | 公開日 | 1992-01-15 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | 主引用文献 | Molecular dynamics refinement of a thermitase-eglin-c complex at 1.98 A resolution and comparison of two crystal forms that differ in calcium content. J.Mol.Biol., 210, 1989
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4EG3
| Trypanosoma brucei methionyl-tRNA synthetase in complex with product methionyl-adenylate | 分子名称: | GLYCEROL, Methionyl-tRNA synthetase, putative, ... | 著者 | Koh, C.Y, Kim, J.E, Shibata, S, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J. | 登録日 | 2012-03-30 | 公開日 | 2012-09-12 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | 主引用文献 | Distinct States of Methionyl-tRNA Synthetase Indicate Inhibitor Binding by Conformational Selection. Structure, 20, 2012
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