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PDB: 19 件

8ADD
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Viral tegument-like DUBs
分子名称: ATP-dependent DNA helicase
著者Erven, I, Abraham, E.T, Hermanns, T, Hofmann, K, Baumann, U.
登録日2022-07-08
公開日2023-02-15
最終更新日2024-09-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A widely distributed family of eukaryotic and bacterial deubiquitinases related to herpesviral large tegument proteins.
Nat Commun, 13, 2022
3ZNX
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Crystal structure of the OTU domain of OTULIN D336A mutant
分子名称: CALCIUM ION, CHLORIDE ION, GLYCEROL, ...
著者Keusekotten, K, Elliott, P.R, Glockner, L, Kulathu, Y, Wauer, T, Krappmann, D, Hofmann, K, Komander, D.
登録日2013-02-18
公開日2013-06-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Otulin Antagonizes Lubac Signaling by Specifically Hydrolyzing met1-Linked Polyubiquitin.
Cell(Cambridge,Mass.), 153, 2013
3ZNZ
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Crystal structure of OTULIN OTU domain (C129A) in complex with Met1- di ubiquitin
分子名称: POLYUBIQUITIN-C, PROTEIN FAM105B, SULFATE ION
著者Keusekotten, K, Elliott, P.R, Glockner, L, Kulathu, Y, Wauer, T, Krappmann, D, Hofmann, K, Komander, D.
登録日2013-02-18
公開日2013-06-26
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Otulin Antagonizes Lubac Signaling by Specifically Hydrolyzing met1-Linked Polyubiquitin.
Cell(Cambridge,Mass.), 153, 2013
3ZNV
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Crystal structure of the OTU domain of OTULIN at 1.3 Angstroms.
分子名称: CALCIUM ION, CHLORIDE ION, GLYCEROL, ...
著者Keusekotten, K, Elliott, P.R, Glockner, L, Kulathu, Y, Wauer, T, Krappmann, D, Hofmann, K, Komander, D.
登録日2013-02-18
公開日2013-06-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Otulin Antagonizes Lubac Signaling by Specifically Hydrolyzing met1-Linked Polyubiquitin.
Cell(Cambridge,Mass.), 153, 2013
8CMR
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Linear specific OTU-type DUB SnOTU from the pathogen S. negenvensis in complex with linear di-ubiquitin
分子名称: OTU domain-containing protein, Polyubiquitin-B
著者Uthoff, M, Hermanns, T, Boll, V, Hofmann, K, Baumann, U.
登録日2023-02-21
公開日2023-11-22
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Functional and structural diversity in deubiquitinases of the Chlamydia-like bacterium Simkania negevensis.
Nat Commun, 14, 2023
4BKG
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BU of 4bkg by Molmil
crystal structure of human diSUMO-2
分子名称: SMALL UBIQUITIN-RELATED MODIFIER 2
著者Keusekotten, K, Bade, V.N, Meyer-Teschendorf, K, Sriramachandran, A, Fischer-Schrader, K, Krause, A, Horst, C, Hofmann, K, Dohmen, R.J, Praefcke, G.J.K.
登録日2013-04-25
公開日2013-11-06
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Multivalent Interactions of the Sumo-Interaction Motifs in the Ring-Finger Protein 4 (Rnf4) Determine the Specificity for Chains of the Small Ubiquitin-Related Modifier (Sumo).
Biochem.J., 457, 2014
7OJE
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BU of 7oje by Molmil
Crystal structure of the covalent complex between Tribolium castaneum deubiquitinase ZUP and Ubiquitin-PA
分子名称: 1,2-ETHANEDIOL, CITRIC ACID, Lys-63-specific deubiquitinase ZUFSP, ...
著者Pichlo, C, Hermanns, T, Hofmann, K, Baumann, U.
登録日2021-05-14
公開日2022-02-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献A structural basis for the diverse linkage specificities within the ZUFSP deubiquitinase family.
Nat Commun, 13, 2022
7OIY
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Crystal structure of the ZUFSP family member Mug105
分子名称: SODIUM ION, Ubiquitin carboxyl-terminal hydrolase mug105
著者Pichlo, C, Hermanns, T, Hofmann, K, Baumann, U.
登録日2021-05-12
公開日2022-02-02
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献A structural basis for the diverse linkage specificities within the ZUFSP deubiquitinase family.
Nat Commun, 13, 2022
8ADB
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Viral tegument-like DUBs
分子名称: CITRIC ACID, Deubiquitinating enzyme, Ubiquitin, ...
著者Erven, I, Abraham, E.T, Hermanns, T, Baumann, U, Hofmann, K.
登録日2022-07-08
公開日2023-02-15
最終更新日2024-09-04
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献A widely distributed family of eukaryotic and bacterial deubiquitinases related to herpesviral large tegument proteins.
Nat Commun, 13, 2022
8ADC
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BU of 8adc by Molmil
Viral tegument-like DUBs
分子名称: Deubiquitinating enzyme
著者Erven, I, Abraham, E.T, Hermanns, T, Baumann, U, Hofmann, K.
登録日2022-07-08
公開日2023-02-15
最終更新日2024-09-04
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A widely distributed family of eukaryotic and bacterial deubiquitinases related to herpesviral large tegument proteins.
Nat Commun, 13, 2022
6EI1
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BU of 6ei1 by Molmil
Crystal structure of the covalent complex between deubiquitinase ZUFSP (ZUP1) and Ubiquitin-PA
分子名称: GLYCEROL, MALONATE ION, Polyubiquitin-B, ...
著者Pichlo, C, Baumann, U, Hofmann, K, Hermanns, T.
登録日2017-09-16
公開日2018-03-07
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (1.732 Å)
主引用文献A family of unconventional deubiquitinases with modular chain specificity determinants.
Nat Commun, 9, 2018
8Q00
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TssM-Ub-PA complex - A USP-like DUB from B. pseudomallei (193-430) reacted with Ub-PA
分子名称: 1,2-ETHANEDIOL, CITRATE ANION, Polyubiquitin-B, ...
著者Uthoff, M, Hermanns, T, Hofmann, K, Baumann, U.
登録日2023-07-27
公開日2023-12-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献The structural basis for deubiquitination by the fingerless USP-type effector TssM.
Life Sci Alliance, 7, 2024
8PZ3
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TssM - A USP-like DUB from B. pseudomallei (193-430)
分子名称: TssM
著者Uthoff, M, Hermanns, T, Hofmann, K, Baumann, U.
登録日2023-07-26
公開日2023-12-13
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献The structural basis for deubiquitination by the fingerless USP-type effector TssM.
Life Sci Alliance, 7, 2024
4AE4
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BU of 4ae4 by Molmil
The UBAP1 subunit of ESCRT-I interacts with ubiquitin via a novel SOUBA domain
分子名称: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, POTASSIUM ION, ...
著者Agromayor, M, Soler, N, Caballe, A, Kueck, T, Freund, S.M, Allen, M.D, Bycroft, M, Perisic, O, Ye, Y, McDonald, B, Scheel, H, Hofmann, K, Neil, S.J.D, Martin-Serrano, J, Williams, R.L.
登録日2012-01-06
公開日2012-03-21
最終更新日2018-02-28
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献The UBAP1 subunit of ESCRT-I interacts with ubiquitin via a SOUBA domain.
Structure, 20, 2012
1B89
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CLATHRIN HEAVY CHAIN PROXIMAL LEG SEGMENT (BOVINE)
分子名称: PROTEIN (CLATHRIN HEAVY CHAIN)
著者Ybe, J.A, Brodsky, F.M, Hofmann, K, Lin, K, Liu, S.-H, Chen, L, Earnest, T.N, Fletterick, R.J, Hwang, P.K.
登録日1999-05-27
公開日1999-06-04
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Clathrin self-assembly is mediated by a tandemly repeated superhelix.
Nature, 399, 1999
2VHF
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BU of 2vhf by Molmil
Structure of the CYLD USP domain
分子名称: UBIQUITIN CARBOXYL-TERMINAL HYDROLASE CYLD, ZINC ION
著者Komander, D, Lord, C.J, Scheel, H, Swift, S, Hofmann, K, Ashworth, A, Barford, D.
登録日2007-11-21
公開日2008-03-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Structure of the Cyld Usp Domain Explains its Specificity for Lys63-Linked Polyubiquitin and Reveals a B-Box Module
Mol.Cell.Biol., 29, 2008
2WWZ
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BU of 2wwz by Molmil
TAB2 NZF DOMAIN IN COMPLEX WITH Lys63-linked di-ubiquitin, P212121
分子名称: MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7-INTERACTING PROTEIN 2, UBIQUITIN, ZINC ION
著者Kulathu, Y, Akutsu, M, Bremm, A, Hofmann, K, Komander, D.
登録日2009-10-30
公開日2009-11-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Two-Sided Ubiquitin Binding Explains Specificity of the Tab2 Nzf Domain
Nat.Struct.Mol.Biol., 16, 2009
2WX0
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BU of 2wx0 by Molmil
TAB2 NZF DOMAIN IN COMPLEX WITH Lys63-linked di-ubiquitin, P21
分子名称: MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7-INTERACTING PROTEIN 2, UBIQUITIN, ZINC ION
著者Kulathu, Y, Akutsu, M, Bremm, A, Hofmann, K, Komander, D.
登録日2009-10-30
公開日2009-11-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Two-Sided Ubiquitin Binding Explains Specificity of the Tab2 Nzf Domain
Nat.Struct.Mol.Biol., 16, 2009
2WX1
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TAB2 NZF DOMAIN IN COMPLEX WITH Lys63-linked tri-ubiquitin, P212121
分子名称: MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 7-INTERACTING PROTEIN 2, UBIQUITIN, ZINC ION
著者Kulathu, Y, Akutsu, M, Bremm, A, Hofmann, K, Komander, D.
登録日2009-10-30
公開日2009-11-24
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Two-Sided Ubiquitin Binding Explains Specificity of the Tab2 Nzf Domain
Nat.Struct.Mol.Biol., 16, 2009

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