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PDB: 26 results

4JVB
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BU of 4jvb by Molmil
Crystal structure of PDE6D in complex with the inhibitor rac-2
Descriptor: 1-benzyl-2-(4-{[(2R)-2-(2-phenyl-1H-benzimidazol-1-yl)pent-4-en-1-yl]oxy}phenyl)-1H-benzimidazole, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta
Authors:Gunther, Z, Papke, B, Ismail, S, Vartak, N, Chandra, A, Hoffmann, M, Hahn, S, Triola, G, Wittinghofer, A, Bastiaens, P, Waldmann, H.
Deposit date:2013-03-25
Release date:2013-05-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Small molecule inhibition of the KRAS PDEd interaction impairs oncogenic KRAS signalling
Nature, 497, 2013
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