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PDB: 7 件
1ZP2
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BU of 1zp2 by Molmil
Structure of the Mediator subunit cyclin C
分子名称: RNA polymerase II holoenzyme cyclin-like subunit
著者Hoeppner, S, Baumli, S, Cramer, P.
登録日2005-05-16
公開日2005-07-19
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the Mediator Subunit Cyclin C and its Implications for CDK8 Function.
J.Mol.Biol., 350, 2005
4EAW
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BU of 4eaw by Molmil
HCV NS5B in complex with IDX375
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, N-{(1S)-3-[(5S)-5-tert-butyl-1-(3,3-dimethylbutyl)-4-hydroxy-2-oxo-2,5-dihydro-1H-pyrrol-3-yl]-1-ethoxy-1-oxido-1,4-dihydro-2,4,1-benzodiazaphosphinin-7-yl}methanesulfonamide, ...
著者Dousson, C.B, Paparin, J.-L, Surleraux, D, Augustin, M, Blaesse, M, Hoeppner, S, Krapp, S, Wenzkowski, C.
登録日2012-03-22
公開日2013-03-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献HCV NS5B in complex with IDX375
To be Published
2HZM
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BU of 2hzm by Molmil
Structure of the Mediator head subcomplex Med18/20
分子名称: PHOSPHATE ION, RNA polymerase II mediator complex subunit 18, RNA polymerase II mediator complex subunit 20
著者Lariviere, L, Geiger, S, Hoeppner, S, Rother, S, Straesser, K, Cramer, P.
登録日2006-08-09
公開日2006-09-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20.
Nat.Struct.Mol.Biol., 13, 2006
2HZS
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BU of 2hzs by Molmil
Structure of the Mediator head submodule Med8C/18/20
分子名称: RNA polymerase II mediator complex subunit 18, RNA polymerase II mediator complex subunit 20, RNA polymerase II mediator complex subunit 8
著者Lariviere, L, Geiger, S, Hoeppner, S, Rother, S, Straesser, K, Cramer, P.
登録日2006-08-09
公開日2006-09-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure and TBP binding of the Mediator head subcomplex Med8-Med18-Med20.
Nat.Struct.Mol.Biol., 13, 2006
1YKE
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BU of 1yke by Molmil
Structure of the mediator MED7/MED21 subcomplex
分子名称: RNA polymerase II holoenzyme component SRB7, RNA polymerase II mediator complex protein MED7
著者Baumli, S, Hoeppner, S, Cramer, P.
登録日2005-01-18
公開日2005-02-22
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献A conserved mediator hinge revealed in the structure of the MED7.MED21 (Med7.Srb7) heterodimer.
J.Biol.Chem., 280, 2005
1YKH
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BU of 1ykh by Molmil
Structure of the mediator MED7/MED21 (Med7/Srb7) subcomplex
分子名称: RNA polymerase II holoenzyme component SRB7, RNA polymerase II mediator complex protein MED7
著者Baumli, S, Hoeppner, S, Cramer, P.
登録日2005-01-18
公開日2005-02-22
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A conserved mediator hinge revealed in the structure of the MED7.MED21 (Med7.Srb7) heterodimer.
J.Biol.Chem., 280, 2005
5M6U
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BU of 5m6u by Molmil
HUMAN PI3KDELTA IN COMPLEX WITH LASW1579
分子名称: 4-azanyl-6-[[(1~{S})-1-(4-oxidanylidene-3-phenyl-pyrrolo[2,1-f][1,2,4]triazin-2-yl)ethyl]amino]pyrimidine-5-carbonitrile, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
著者Segarra, V, Hernandez, B, Lozoya, E, Blaesse, M, Hoeppner, S, Jestel, A.
登録日2016-10-26
公開日2017-02-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Discovery of a Potent, Selective, and Orally Available PI3K delta Inhibitor for the Treatment of Inflammatory Diseases.
ACS Med Chem Lett, 8, 2017

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件を2024-10-30に公開中

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