5A6E
| Cryo-EM structure of the Slo2.2 Na-activated K channel | Descriptor: | GATING RING OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1, PORE DOMAIN OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1, RCK2 ELABORATION OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1, ... | Authors: | Hite, R.K, Yuan, P, Li, Z, Hsuing, Y, Walz, T, MacKinnon, R. | Deposit date: | 2015-06-25 | Release date: | 2015-10-14 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Cryo-Electron Microscopy Structure of the Slo2.2 Na1-Activated K1 Channel Nature, 527, 2015
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5A6G
| Cryo-EM structure of the Slo2.2 Na-activated K channel | Descriptor: | PORE DOMAIN OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1, S1-S4 DOMAIN OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1 | Authors: | Hite, R.K, Yuan, P, Li, Z, Hsuing, Y, Walz, T, MacKinnon, R. | Deposit date: | 2015-06-25 | Release date: | 2015-10-14 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (5.2 Å) | Cite: | Cryo-Electron Microscopy Structure of the Slo2.2 Na1-Activated K1 Channel Nature, 527, 2015
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5A6F
| Cryo-EM structure of the Slo2.2 Na-activated K channel | Descriptor: | GATING RING OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1, RCK2 ELABORATION OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1 | Authors: | Hite, R.K, Yuan, P, Li, Z, Hsuing, Y, Walz, T, MacKinnon, R. | Deposit date: | 2015-06-25 | Release date: | 2015-10-14 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Cryo-Electron Microscopy Structure of the Slo2.2 Na1-Activated K1 Channel Nature, 527, 2015
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8UBZ
| Choline-bound FLVCR1 | Descriptor: | CHOLESTEROL HEMISUCCINATE, CHOLINE ION, Heme transporter FLVCR1 | Authors: | Hite, R.K, Son, Y. | Deposit date: | 2023-09-25 | Release date: | 2024-03-27 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.02 Å) | Cite: | Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1. Nature, 629, 2024
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8UBX
| Ethanolamine-bound FLVCR1 | Descriptor: | CHOLESTEROL HEMISUCCINATE, ETHANOLAMINE, Heme transporter FLVCR1 | Authors: | Hite, R.K, Son, Y. | Deposit date: | 2023-09-25 | Release date: | 2024-03-27 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1. Nature, 629, 2024
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8UC0
| Endogenous ligand bound FLVCR1 | Descriptor: | CHOLESTEROL HEMISUCCINATE, Heme transporter FLVCR1 | Authors: | Hite, R.K, Son, Y. | Deposit date: | 2023-09-25 | Release date: | 2024-03-27 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.42 Å) | Cite: | Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1. Nature, 629, 2024
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8UBW
| Choline-bound FLVCR1 | Descriptor: | CHOLESTEROL HEMISUCCINATE, CHOLINE ION, Heme transporter FLVCR1 | Authors: | Hite, R.K, Son, Y. | Deposit date: | 2023-09-25 | Release date: | 2024-03-27 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.59 Å) | Cite: | Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1. Nature, 629, 2024
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8UBY
| Choline-bound FLVCR1 | Descriptor: | CHOLESTEROL HEMISUCCINATE, CHOLINE ION, Heme transporter FLVCR1 | Authors: | Hite, R.K, Son, Y. | Deposit date: | 2023-09-25 | Release date: | 2024-03-27 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.67 Å) | Cite: | Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1. Nature, 629, 2024
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6DRA
| Low IP3 Ca2+ human type 3 1,4,5-inositol trisphosphate receptor | Descriptor: | CALCIUM ION, Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION | Authors: | Hite, R.K, Paknejad, N. | Deposit date: | 2018-06-11 | Release date: | 2018-08-01 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.96 Å) | Cite: | Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3. Nat. Struct. Mol. Biol., 25, 2018
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6DQJ
| Human type 3 1,4,5-inositol trisphosphate receptor in a ligand-free state | Descriptor: | Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION | Authors: | Hite, R.K, Paknejad, N. | Deposit date: | 2018-06-11 | Release date: | 2018-08-01 | Last modified: | 2018-08-15 | Method: | ELECTRON MICROSCOPY (3.49 Å) | Cite: | Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3. Nat. Struct. Mol. Biol., 25, 2018
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6DQN
| Class 1 IP3-bound human type 3 1,4,5-inositol trisphosphate receptor | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION | Authors: | Hite, R.K, Paknejad, N. | Deposit date: | 2018-06-11 | Release date: | 2018-08-01 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3. Nat. Struct. Mol. Biol., 25, 2018
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6DR0
| Class 5 IP3-bound human type 3 1,4,5-inositol trisphosphate receptor | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION | Authors: | Hite, R.K, Paknejad, N. | Deposit date: | 2018-06-11 | Release date: | 2018-08-01 | Last modified: | 2018-08-15 | Method: | ELECTRON MICROSCOPY (4.47 Å) | Cite: | Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3. Nat. Struct. Mol. Biol., 25, 2018
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6DQZ
| Class 4 IP3-bound human type 3 1,4,5-inositol trisphosphate receptor | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION | Authors: | Hite, R.K, Paknejad, N. | Deposit date: | 2018-06-11 | Release date: | 2018-08-01 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (6.01 Å) | Cite: | Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3. Nat. Struct. Mol. Biol., 25, 2018
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6DQS
| Class 3 IP3-bound human type 3 1,4,5-inositol trisphosphate receptor | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION | Authors: | Hite, R.K, Paknejad, N. | Deposit date: | 2018-06-11 | Release date: | 2018-08-01 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (4.12 Å) | Cite: | Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3. Nat. Struct. Mol. Biol., 25, 2018
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6DR2
| Ca2+-bound human type 3 1,4,5-inositol trisphosphate receptor | Descriptor: | CALCIUM ION, Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION | Authors: | Hite, R.K, Paknejad, N. | Deposit date: | 2018-06-11 | Release date: | 2018-07-18 | Last modified: | 2018-08-15 | Method: | ELECTRON MICROSCOPY (4.33 Å) | Cite: | Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3. Nat. Struct. Mol. Biol., 25, 2018
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6DQV
| Class 2 IP3-bound human type 3 1,4,5-inositol trisphosphate receptor | Descriptor: | D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ZINC ION | Authors: | Hite, R.K, Paknejad, N. | Deposit date: | 2018-06-11 | Release date: | 2018-08-01 | Last modified: | 2019-11-20 | Method: | ELECTRON MICROSCOPY (3.82 Å) | Cite: | Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3. Nat. Struct. Mol. Biol., 25, 2018
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6DRC
| High IP3 Ca2+ human type 3 1,4,5-inositol trisphosphate receptor | Descriptor: | CALCIUM ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, Inositol 1,4,5-trisphosphate receptor type 3, ... | Authors: | Hite, R.K, Paknejad, N. | Deposit date: | 2018-06-11 | Release date: | 2018-08-01 | Last modified: | 2024-10-16 | Method: | ELECTRON MICROSCOPY (3.92 Å) | Cite: | Structural basis for the regulation of inositol trisphosphate receptors by Ca2+and IP3. Nat. Struct. Mol. Biol., 25, 2018
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5U76
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5U70
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3M9I
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7TD0
| Lysophosphatidic acid receptor 1-Gi complex bound to LPA | Descriptor: | (2R)-2-hydroxy-3-(phosphonooxy)propyl (9E)-octadec-9-enoate, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Liu, S, Paknejad, N, Zhu, L, Kihara, Y, Ray, D, Chun, J, Liu, W, Hite, R.K, Huang, X.Y. | Deposit date: | 2021-12-30 | Release date: | 2022-02-09 | Last modified: | 2022-02-23 | Method: | ELECTRON MICROSCOPY (2.83 Å) | Cite: | Differential activation mechanisms of lipid GPCRs by lysophosphatidic acid and sphingosine 1-phosphate. Nat Commun, 13, 2022
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7TD2
| Lysophosphatidic acid receptor 1-Gi complex bound to LPA, state a | Descriptor: | (2R)-2-hydroxy-3-(phosphonooxy)propyl (9E)-octadec-9-enoate, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Liu, S, Paknejad, N, Zhu, L, Kihara, Y, Ray, D, Chun, J, Liu, W, Hite, R.K, Huang, X.Y. | Deposit date: | 2021-12-30 | Release date: | 2022-02-09 | Last modified: | 2022-02-23 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Differential activation mechanisms of lipid GPCRs by lysophosphatidic acid and sphingosine 1-phosphate. Nat Commun, 13, 2022
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7TD3
| Sphingosine-1-phosphate receptor 1-Gi complex bound to S1P | Descriptor: | (2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Liu, S, Paknejad, N, Zhu, L, Kihara, Y, Ray, D, Chun, J, Liu, W, Hite, R.K, Huang, X.Y. | Deposit date: | 2021-12-30 | Release date: | 2022-02-09 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Differential activation mechanisms of lipid GPCRs by lysophosphatidic acid and sphingosine 1-phosphate. Nat Commun, 13, 2022
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7TD1
| Lysophosphatidic acid receptor 1-Gi complex bound to LPA, state a | Descriptor: | (2R)-2-hydroxy-3-(phosphonooxy)propyl (9E)-octadec-9-enoate, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Liu, S, Paknejad, N, Zhu, L, Kihara, Y, Ray, D, Chun, J, Liu, W, Hite, R.K, Huang, X.Y. | Deposit date: | 2021-12-30 | Release date: | 2022-02-09 | Last modified: | 2022-02-23 | Method: | ELECTRON MICROSCOPY (3.08 Å) | Cite: | Differential activation mechanisms of lipid GPCRs by lysophosphatidic acid and sphingosine 1-phosphate. Nat Commun, 13, 2022
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7TD4
| Sphingosine-1-phosphate receptor 1-Gi complex bound to Siponimod | Descriptor: | 1-[[4-[(~{E})-~{N}-[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]-~{C}-methyl-carbonimidoyl]-2-ethyl-phenyl]methyl]azetidine-3-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Liu, S, Paknejad, N, Zhu, L, Kihara, Y, Ray, D, Chun, J, Liu, W, Hite, R.K, Huang, X.Y. | Deposit date: | 2021-12-30 | Release date: | 2022-02-09 | Last modified: | 2024-10-09 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Differential activation mechanisms of lipid GPCRs by lysophosphatidic acid and sphingosine 1-phosphate. Nat Commun, 13, 2022
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