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PDB: 10 件

5OJE
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Endothiapepsin with Ligand VSK-B24
分子名称: (2~{S})-2-azanyl-3-(1~{H}-indol-3-yl)-~{N}-[2-(2,4,6-trimethylphenyl)ethyl]propanamide, DIMETHYL SULFOXIDE, Endothiapepsin, ...
著者Gierse, R.M, Magari, F, Groves, M.R, Heine, A, Klebe, G, Hirsch, A.
登録日2017-07-21
公開日2018-09-12
最終更新日2018-11-21
実験手法X-RAY DIFFRACTION (1.579 Å)
主引用文献Design and Synthesis of Bioisosteres of Acylhydrazones as Stable Inhibitors of the Aspartic Protease Endothiapepsin.
ChemMedChem, 13, 2018
8A29
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Apo 1-deoxy-D-xylulose 5-phosphate synthase from Pseudomonas aeruginosa
分子名称: 1-deoxy-D-xylulose-5-phosphate synthase, CALCIUM ION, CHLORIDE ION, ...
著者Hamid, R, Adam, S, Lacour, A, Monjas, L, Hirsch, A.
登録日2022-06-02
公開日2023-06-14
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献1-deoxy-D-xylulose-5-phosphate synthase from Pseudomonas aeruginosa and Klebsiella pneumoniae reveals conformational changes upon cofactor binding.
J.Biol.Chem., 299, 2023
7Z68
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Pseudomonas aeruginosa Elastase in complex with a Thiol based inhibitor (R-and S-configured)
分子名称: (2~{R})-~{N}-[4-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]sulfanylphenyl]-3-phenyl-2-sulfanyl-propanamide, CALCIUM ION, GLYCEROL, ...
著者Klein, A, Hirsch, A.
登録日2022-03-11
公開日2023-09-20
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Dual inhibitors of Pseudomonas aeruginosa virulence factors LecA and LasB
To Be Published
8A45
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Structural analysis of 1-deoxy-D-xylulose 5-phosphate synthase from Pseudomonas aeruginosa with 2-acetyl thiamine diphosphate
分子名称: 1-deoxy-D-xylulose-5-phosphate synthase, 2-ACETYL-THIAMINE DIPHOSPHATE, CALCIUM ION, ...
著者Hamid, R, Hirsch, A.
登録日2022-06-10
公開日2023-07-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献1-deoxy-D-xylulose-5-phosphate synthase from Pseudomonas aeruginosa and Klebsiella pneumoniae reveals conformational changes upon cofactor binding.
J.Biol.Chem., 299, 2023
8A4D
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BU of 8a4d by Molmil
1-deoxy-D-xylulose 5-phosphate synthase from Pseudomonas aeruginosa with a thiamine analog inhibitor
分子名称: 1-deoxy-D-xylulose-5-phosphate synthase, 2-{3-[(4-amino-2-methylpyrimidin-5-yl)methyl]phenyl}ethanol, CALCIUM ION, ...
著者Hamid, R, Hirsch, A.
登録日2022-06-10
公開日2023-07-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献1-deoxy-D-xylulose-5-phosphate synthase from Pseudomonas aeruginosa and Klebsiella pneumoniae reveals conformational changes upon cofactor binding.
J.Biol.Chem., 299, 2023
8A5K
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BU of 8a5k by Molmil
Structural analysis of 1-deoxy-D-xylulose 5-phosphate synthase from Pseudomonas aeruginosa and Klebsiella pneumoniae reveals conformational changes upon cofactor binding
分子名称: 1-deoxy-D-xylulose-5-phosphate synthase, CALCIUM ION, GLYCEROL, ...
著者Hamid, R, Hirsch, A.
登録日2022-06-15
公開日2023-07-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献1-deoxy-D-xylulose-5-phosphate synthase from Pseudomonas aeruginosa and Klebsiella pneumoniae reveals conformational changes upon cofactor binding.
J.Biol.Chem., 299, 2023
8A9C
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BU of 8a9c by Molmil
Structure of truncated 1-deoxy-D-xylulose 5-phosphate synthase (DXS) from Klebsiella pneumoniae in complex with cofactor TPP
分子名称: 1-deoxy-D-xylulose-5-phosphate synthase, MAGNESIUM ION, THIAMINE DIPHOSPHATE
著者Adam, S, Hirsch, A.
登録日2022-06-28
公開日2023-07-12
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of truncated 1-deoxy-D-xylulose 5-phosphate synthase (DXS) from Klebsiella pneumoniae in complex with cofactor TPP
To Be Published
8A8Y
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BU of 8a8y by Molmil
Structure of truncated 1-deoxy-D-xylulose 5-phosphate synthase (DXS) from Klebsiella pneumoniae
分子名称: 1-deoxy-D-xylulose-5-phosphate synthase
著者Adam, S, Hirsch, A.
登録日2022-06-24
公開日2023-07-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.10000443 Å)
主引用文献Structure of truncated 1-deoxy-D-xylulose 5-phosphate synthase (DXS) from Klebsiella pneumoniae
To Be Published
4V67
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Crystal structure of a translation termination complex formed with release factor RF2.
分子名称: 16S RRNA, 23S RRNA, 30S ribosomal protein S10, ...
著者Korostelev, A, Asahara, H, Lancaster, L, Laurberg, M, Hirschi, A, Noller, H.F.
登録日2008-10-27
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of a translation termination complex formed with release factor RF2.
Proc.Natl.Acad.Sci.USA, 105, 2008
4LPA
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BU of 4lpa by Molmil
Crystal structure of a Cdc6 phosphopeptide in complex with Cks1
分子名称: Cyclin-dependent kinases regulatory subunit
著者McGrath, D.A, Balog, E.R.M, Koivomagi, M, Lucena, R, Mai, M.V, Hirschi, A, Kellogg, D.R, Loog, M, Rubin, S.M.
登録日2013-07-15
公開日2013-11-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Cks confers specificity to phosphorylation-dependent CDK signaling pathways.
Nat.Struct.Mol.Biol., 20, 2013

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件を2024-11-06に公開中

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