6BQX
| Crystal structure of Escherichia coli DsbA in complex with N-methyl-1-(4-phenoxyphenyl)methanamine | 分子名称: | N-methyl-1-(4-phenoxyphenyl)methanamine, Thiol:disulfide interchange protein DsbA | 著者 | Heras, B, Totsika, M, Paxman, J.J, Wang, G, Scanlon, M.J. | 登録日 | 2017-11-29 | 公開日 | 2017-12-27 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (1.992 Å) | 主引用文献 | Inhibition of Diverse DsbA Enzymes in Multi-DsbA Encoding Pathogens. Antioxid. Redox Signal., 29, 2018
|
|
6BR4
| Crystal structure of Escherichia coli DsbA in complex with {N}-methyl-1-(3-thiophen-2-ylphenyl)methanamine | 分子名称: | COPPER (II) ION, Thiol:disulfide interchange protein DsbA, ~{N}-methyl-1-(3-thiophen-2-ylphenyl)methanamine | 著者 | Heras, B, Totsika, M, Paxman, J.J, Wang, G, Scanlon, M.J, Martin, J.L. | 登録日 | 2017-11-29 | 公開日 | 2017-12-27 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | 主引用文献 | Inhibition of Diverse DsbA Enzymes in Multi-DsbA Encoding Pathogens. Antioxid. Redox Signal., 29, 2018
|
|
6DPS
| |
6DNU
| |
7S1C
| Crystal structure of E.coli DsbA in complex with compound MIPS-0001897 (compound 1) | 分子名称: | COPPER (II) ION, Thiol:disulfide interchange protein DsbA, ~{N}-methyl-1-(3-thiophen-3-ylphenyl)methanamine | 著者 | Heras, B, Scanlon, M.J, Martin, J.L, Sharma, P. | 登録日 | 2021-09-02 | 公開日 | 2023-02-08 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.949 Å) | 主引用文献 | Fluoromethylketone-fragment conjugates designed as covalent modifiers of EcDsbA are atypical substrates Chemrxiv, 2022
|
|
7S1F
| Crystal structure of E.coli DsbA in complex with compound MIPS-0001886 (compound 38) | 分子名称: | 1-[(3-thiophen-3-ylphenyl)methyl]-3~{H}-pyrrol-2-one, COPPER (II) ION, GLYCEROL, ... | 著者 | Heras, B, Scanlon, M.J, Martin, J.L, Caria, S. | 登録日 | 2021-09-02 | 公開日 | 2023-02-08 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Fluoromethylketone-fragment conjugates designed as covalent modifiers of EcDsbA are atypical substrates Chemrxiv, 2022
|
|
7S1D
| Crystal structure of E.coli DsbA in complex with compound MIPS-0001877 (compound 39) | 分子名称: | 1-[3-(thiophen-3-yl)benzyl]piperidin-2-one, COPPER (II) ION, Thiol:disulfide interchange protein DsbA | 著者 | Heras, B, Scanlon, M.J, Martin, J.L, Caria, S. | 登録日 | 2021-09-02 | 公開日 | 2023-02-08 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Fluoromethylketone-fragment conjugates designed as covalent modifiers of EcDsbA are atypical substrates Chemrxiv, 2022
|
|
7S1L
| Crystal structure of E.coli DsbA in complex with compound MIPS-0001896 (compound 72) | 分子名称: | COPPER (II) ION, Thiol:disulfide interchange protein DsbA, methyl cis-4-({[3-(thiophen-3-yl)benzyl]amino}methyl)cyclohexanecarboxylate | 著者 | Heras, B, Scanlon, M.J, Martin, J.L, Caria, S. | 登録日 | 2021-09-02 | 公開日 | 2023-02-08 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.623 Å) | 主引用文献 | Fluoromethylketone-fragment conjugates designed as covalent modifiers of EcDsbA are atypical substrates Chemrxiv, 2022
|
|
3BCI
| |
5EK5
| STRUCTURAL CHARACTERIZATION OF IRMA FROM ESCHERICHIA COLI | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, FORMIC ACID, ... | 著者 | Heras, B, Moriel, D.G, Paxman, J.J, Schembri, M.A. | 登録日 | 2015-11-03 | 公開日 | 2016-03-09 | 最終更新日 | 2016-07-13 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Molecular and Structural Characterization of a Novel Escherichia coli Interleukin Receptor Mimic Protein. Mbio, 7, 2016
|
|
3BCK
| |
3BD2
| |
1V58
| Crystal Structure Of the Reduced Protein Disulfide Bond Isomerase DsbG | 分子名称: | SULFATE ION, Thiol:disulfide interchange protein dsbG | 著者 | Heras, B, Edeling, M.A, Schirra, H.J, Raina, S, Martin, J.L. | 登録日 | 2003-11-21 | 公開日 | 2004-06-29 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal structures of the DsbG disulfide isomerase reveal an unstable disulfide Proc.Natl.Acad.Sci.USA, 101, 2004
|
|
1V57
| Crystal Structure of the Disulfide Bond Isomerase DsbG | 分子名称: | SULFATE ION, Thiol:disulfide interchange protein dsbG | 著者 | Heras, B, Edeling, M.A, Schirra, H.J, Raina, S, Martin, J.L. | 登録日 | 2003-11-21 | 公開日 | 2004-06-29 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures of the DsbG disulfide isomerase reveal an unstable disulfide Proc.Natl.Acad.Sci.USA, 101, 2004
|
|
3L9U
| |
3L9V
| Crystal Structure of Salmonella enterica serovar Typhimurium SrgA | 分子名称: | 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, HEXAETHYLENE GLYCOL, O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL, ... | 著者 | Heras, B, Jarrott, R, Shouldice, S.R, Guncar, G. | 登録日 | 2010-01-05 | 公開日 | 2010-03-09 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2.151 Å) | 主引用文献 | Structural and functional characterization of three DsbA paralogues from Salmonella enterica serovar typhimurium J.Biol.Chem., 285, 2010
|
|
3L9S
| |
6PBU
| ClpP1 from Mycobacterium smegmatis | 分子名称: | ATP-dependent Clp protease proteolytic subunit, MALONATE ION | 著者 | Heras, B, Nagpal, J, Dougan, D.A. | 登録日 | 2019-06-14 | 公開日 | 2019-12-18 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Molecular and structural insights into an asymmetric proteolytic complex (ClpP1P2) from Mycobacterium smegmatis. Sci Rep, 9, 2019
|
|
4KH3
| Structure of a bacterial self-associating protein | 分子名称: | Antigen 43, MALONATE ION | 著者 | Heras, B, Gee, C.L, Schembri, M.A, Totsika, M. | 登録日 | 2013-04-30 | 公開日 | 2014-01-15 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The antigen 43 structure reveals a molecular Velcro-like mechanism of autotransporter-mediated bacterial clumping. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
7TTV
| |
6WHD
| |
4WF5
| Crystal structure of E.Coli DsbA soaked with compound 4 | 分子名称: | 1,2-ETHANEDIOL, 4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxylic acid, COPPER (II) ION, ... | 著者 | Adams, L.A, Sharma, P, Mohanty, B, Ilyichova, O.V, Mulcair, M.D, Williams, M.L, Gleeson, E.C, Totsika, M, Doak, B.C, Caria, S, Rimmer, K, Shouldice, S.R, Vazirani, M, Headey, S.J, Plumb, B.R, Martin, J.L, Heras, B, Simpson, J.S, Scanlon, M.J. | 登録日 | 2014-09-12 | 公開日 | 2015-01-21 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Application of Fragment-Based Screening to the Design of Inhibitors of Escherichia coli DsbA. Angew.Chem.Int.Ed.Engl., 54, 2015
|
|
4WEY
| Crystal structure of E.Coli DsbA in complex with compound 17 | 分子名称: | 1,2-ETHANEDIOL, N-({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}carbonyl)-L-serine, Thiol:disulfide interchange protein | 著者 | Adams, L.A, Sharma, P, Mohanty, B, Ilyichova, O.V, Mulcair, M.D, Williams, M.L, Gleeson, E.C, Totsika, M, Doak, B.C, Caria, S, Rimmer, K, Shouldice, S.R, Vazirani, M, Headey, S.J, Plumb, B.R, Martin, J.L, Heras, B, Simpson, J.S, Scanlon, M.J. | 登録日 | 2014-09-11 | 公開日 | 2015-01-21 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Application of Fragment-Based Screening to the Design of Inhibitors of Escherichia coli DsbA. Angew.Chem.Int.Ed.Engl., 54, 2015
|
|
4WF4
| Crystal structure of E.Coli DsbA co-crystallised in complex with compound 4 | 分子名称: | 1,2-ETHANEDIOL, 4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxylic acid, Thiol:disulfide interchange protein | 著者 | Adams, L.A, Sharma, P, Mohanty, B, Ilyichova, O.V, Mulcair, M.D, Williams, M.L, Gleeson, E.C, Totsika, M, Doak, B.C, Caria, S, Rimmer, K, Shouldice, S.R, Vazirani, M, Headey, S.J, Plumb, B.R, Martin, J.L, Heras, B, Simpson, J.S, Scanlon, M.J. | 登録日 | 2014-09-12 | 公開日 | 2015-01-21 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Application of Fragment-Based Screening to the Design of Inhibitors of Escherichia coli DsbA. Angew.Chem.Int.Ed.Engl., 54, 2015
|
|
6DNV
| |