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PDB: 96 件

9EQK
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WWP1 WW2-2,3-linker-WW3-WW4-HECT (WWP1-2L34H) with ordered WW2 domain
分子名称: NEDD4-like E3 ubiquitin-protein ligase WWP1
著者Dudey, A.P, Hemmings, A.M.
登録日2024-03-21
公開日2024-05-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Expanding the Inhibitor Space of the WWP1 and WWP2 HECT E3 Ligases
To Be Published
7Z2T
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BU of 7z2t by Molmil
Escherichia coli periplasmic phytase AppA D304A mutant, complex with myo-inositol hexakissulfate
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Acidphosphatase, D-MYO-INOSITOL-HEXASULPHATE, ...
著者Acquistapace, I.M, Brearley, C.A, Hemmings, A.M.
登録日2022-02-28
公開日2022-03-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA.
Int J Mol Sci, 23, 2022
7Z2S
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Escherichia coli periplasmic phytase AppA, complex with myo-inositol hexakissulfate
分子名称: Acidphosphatase, D-MYO-INOSITOL-HEXASULPHATE, NICKEL (II) ION, ...
著者Acquistapace, I.M, Brearley, C.A, Hemmings, A.M.
登録日2022-02-28
公開日2022-03-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA.
Int J Mol Sci, 23, 2022
7Z2Y
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Escherichia coli periplasmic phytase AppA T305E mutant, complex with myo-inositol hexakissulfate
分子名称: Acidphosphatase, D-MYO-INOSITOL-HEXASULPHATE, NICKEL (II) ION
著者Acquistapace, I.M, Brearley, C.A, Hemmings, A.M.
登録日2022-03-01
公開日2022-03-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA.
Int J Mol Sci, 23, 2022
7Z32
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Escherichia coli periplasmic phytase AppA D304A mutant, phosphohistidine intermediate
分子名称: Acidphosphatase, NICKEL (II) ION
著者Acquistapace, I.M, Brearley, C.A, Hemmings, A.M.
登録日2022-03-01
公開日2022-03-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA.
Int J Mol Sci, 23, 2022
7Z1J
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BU of 7z1j by Molmil
Escherichia coli periplasmic phytase AppA, complex with phosphate
分子名称: Acidphosphatase, MAGNESIUM ION, NICKEL (II) ION, ...
著者Acquistapace, I.M, Brearley, C.A, Hemmings, A.M.
登録日2022-02-24
公開日2022-03-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA.
Int J Mol Sci, 23, 2022
7Z2W
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BU of 7z2w by Molmil
Escherichia coli periplasmic phytase AppA D304A,T305E mutant, complex with myo-inositol hexakissulfate
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Acidphosphatase, D-MYO-INOSITOL-HEXASULPHATE, ...
著者Acquistapace, I.M, Brearley, C.A, Hemmings, A.M.
登録日2022-03-01
公開日2022-03-16
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA.
Int J Mol Sci, 23, 2022
7Z3V
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BU of 7z3v by Molmil
Escherichia coli periplasmic phytase AppA D304E mutant, complex with myo-inositol hexakissulfate
分子名称: Acidphosphatase, D-MYO-INOSITOL-HEXASULPHATE, POTASSIUM ION
著者Acquistapace, I.M, Brearley, C.A, Hemmings, A.M.
登録日2022-03-02
公開日2022-06-29
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA.
Int J Mol Sci, 23, 2022
6RXG
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BU of 6rxg by Molmil
Crystal Structure of Bifidobacterium longum Multiple Inositol Polyphosphate Phosphatase Complex with Phosphate
分子名称: Histidine acid phosphatase, PHOSPHATE ION, ZINC ION
著者Zietek, M.A.Z, Brearley, C.A, Hemmings, A.M.
登録日2019-06-07
公開日2020-07-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Snapshots during the catalytic cycle of a histidine acid phytase reveal an induced-fit structural mechanism.
J.Biol.Chem., 295, 2020
8OXE
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BU of 8oxe by Molmil
Inositol 1,3,4-trisphosphate 5/6-kinase 1 from Solanum tuberosum (StITPK1) in complex with ADP/Mg2+
分子名称: ADENOSINE-5'-DIPHOSPHATE, Inositol-tetrakisphosphate 1-kinase, MAGNESIUM ION
著者Faba-Rodriguez, R, Li, A.W.H, Brearley, C.A, Hemmings, A.M.
登録日2023-05-02
公開日2024-03-27
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Crystal Structure and Enzymology of Solanum tuberosum Inositol Tris/Tetrakisphosphate Kinase 1 ( St ITPK1).
Biochemistry, 63, 2024
5FD6
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BU of 5fd6 by Molmil
zinc-bound manganese uptake regulator
分子名称: Ferric uptake regulation protein, GLYCEROL, SULFATE ION, ...
著者Bellini, D, Hemmings, A.M, Walsh, M.A.
登録日2015-12-15
公開日2016-12-28
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献structure of a zinc-bound manganese uptake regulator, mur
To Be Published
3L1T
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BU of 3l1t by Molmil
E. coli NrfA sulfite ocmplex
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Cytochrome c-552, ...
著者Clarke, T.A, Hemmings, A.M, Butt, J.N.
登録日2009-12-14
公開日2010-10-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Kinetic and thermodynamic resolution of the interactions between sulfite and the pentahaem cytochrome NrfA from Escherichia coli
Biochem.J., 431, 2010
4XKT
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BU of 4xkt by Molmil
E coli BFR variant Y149F
分子名称: Bacterioferritin, SULFATE ION
著者Bradley, J.M, Hemmings, A.M, Le Brun, N.E.
登録日2015-01-12
公開日2015-12-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Three Aromatic Residues are Required for Electron Transfer during Iron Mineralization in Bacterioferritin.
Angew.Chem.Int.Ed.Engl., 54, 2015
7PUP
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BU of 7pup by Molmil
INOSITOL 1,3,4-TRISPHOSPHATE 5/6-KINASE 4 from Arabidopsis thaliana (AtITPK4) in complex with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Inositol 1,3,4-trisphosphate 5/6-kinase 4
著者Whitfield, H, He, S, Brearley, C.A, Hemmings, A.M.
登録日2021-09-30
公開日2022-10-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献Diversification in the inositol tris/tetrakisphosphate kinase (ITPK) family: crystal structure and enzymology of the outlier AtITPK4.
Biochem.J., 480, 2023
4FDU
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BU of 4fdu by Molmil
Crystal Structure of a Multiple Inositol Polyphosphate Phosphatase
分子名称: 1,2-ETHANEDIOL, D-MYO-INOSITOL-HEXASULPHATE, Putative multiple inositol polyphosphate histidine phosphatase 1
著者Li, A.W.H, Hemmings, A.M.
登録日2012-05-29
公開日2014-01-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.293 Å)
主引用文献A Bacterial Homolog of a Eukaryotic Inositol Phosphate Signaling Enzyme Mediates Cross-kingdom Dialog in the Mammalian Gut.
Cell Rep, 6, 2014
4FDT
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BU of 4fdt by Molmil
Crystal Structure of a Multiple Inositol Polyphosphate Phosphatase
分子名称: 1,2-ETHANEDIOL, PHOSPHATE ION, Putative multiple inositol polyphosphate histidine phosphatase 1
著者Li, A.W.H, Hemmings, A.M.
登録日2012-05-29
公開日2014-01-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献A Bacterial Homolog of a Eukaryotic Inositol Phosphate Signaling Enzyme Mediates Cross-kingdom Dialog in the Mammalian Gut.
Cell Rep, 6, 2014
3TOR
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BU of 3tor by Molmil
Crystal structure of Escherichia coli NrfA with Europium bound
分子名称: CALCIUM ION, Cytochrome c nitrite reductase, EUROPIUM ION, ...
著者Lockwood, C.W.J, Clarke, T.A, Butt, J.N, Hemmings, A.M, Richardson, D.J.
登録日2011-09-06
公開日2011-12-07
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Characterization of the active site and calcium binding in cytochrome c nitrite reductases.
Biochem.Soc.Trans., 39, 2011
2QIF
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BU of 2qif by Molmil
Crystal structure of a metallochaperone with a tetranuclear Cu(I) cluster
分子名称: ACETATE ION, CALCIUM ION, COPPER (I) ION, ...
著者West, C, Singleton, C, Kihlken, M.A, Le Brun, N.E, Hemmings, A.M.
登録日2007-07-04
公開日2008-07-08
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献A tetranuclear Cu(I) cluster in the metallochaperone protein CopZ.
Biochemistry, 48, 2009
2RDZ
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BU of 2rdz by Molmil
High Resolution Crystal Structure of the Escherichia coli Cytochrome c Nitrite Reductase.
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, Cytochrome c-552, ...
著者Clarke, T.A, Hemmings, A.M, RIchardson, D.J.
登録日2007-09-25
公開日2008-03-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Role of a Conserved Glutamine Residue in Tuning the Catalytic Activity of Escherichia coli Cytochrome c Nitrite Reductase.
Biochemistry, 47, 2008
7ZGG
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BU of 7zgg by Molmil
Crystal Structure of Amycolatopsis jejuensis Multiple Inositol Polyphosphate Phosphatase, phosphate-bound
分子名称: GLYCEROL, Multiple inositol-polyphosphate phosphatase, PHOSPHATE ION
著者Acquistapace, I.M, Brearley, C.A, Hemmings, A.M.
登録日2022-04-03
公開日2022-05-18
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Crystal Structure of Amycolatopsis jejuensis Multiple Inositol Polyphosphate Phosphatase, apo-protein
To Be Published
7ZGF
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BU of 7zgf by Molmil
Crystal Structure of Amycolatopsis jejuensis Multiple Inositol Polyphosphate Phosphatase, apo-protein
分子名称: Multiple inositol-polyphosphate phosphatase
著者Acquistapace, I.M, Brearley, C.A, Hemmings, A.M.
登録日2022-04-03
公開日2022-05-18
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Crystal Structure of Amycolatopsis jejuensis Multiple Inositol Polyphosphate Phosphatase, apo-protein
To Be Published
7ZGH
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BU of 7zgh by Molmil
Crystal Structure of Amycolatopsis jejuensis Multiple Inositol Polyphosphate Phosphatase, complex with myo-inositol hexakissulfate
分子名称: D-MYO-INOSITOL-HEXASULPHATE, GLYCEROL, Multiple inositol-polyphosphate phosphatase
著者Acquistapace, I.M, Brearley, C.A, Hemmings, A.M.
登録日2022-04-03
公開日2022-05-18
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.41 Å)
主引用文献Crystal Structure of Amycolatopsis jejuensis Multiple Inositol Polyphosphate Phosphatase, complex with myo-inositol hexakissulfate
To Be Published
7R5Y
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BU of 7r5y by Molmil
Crystal Structure of Prevotella sp. CAG:617 Multiple Inositol Polyphosphate Phosphatase, complex with myo-inositol hexakissulfate
分子名称: D-MYO-INOSITOL-HEXASULPHATE, Histidine acid phosphatase, SULFATE ION
著者Acquistapace, I.M, Brearley, C.A, Hemmings, A.M.
登録日2022-02-12
公開日2022-05-18
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Crystal Structure of Prevotella sp. CAG:617 Multiple Inositol Polyphosphate Phosphatase, complex with myo-inositol hexakissulfate
To Be Published
6SRR
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BU of 6srr by Molmil
Crystal structure of human SHIP2 catalytic domain
分子名称: Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2
著者Whitfield, H, Brearley, C.A, Hemmings, A.M.
登録日2019-09-05
公開日2021-01-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Allosteric Site on SHIP2 Identified Through Fluorescent Ligand Screening and Crystallography: A Potential New Target for Intervention.
J.Med.Chem., 64, 2021
6SQU
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BU of 6squ by Molmil
Crystal structure of human SHIP2 catalytic domain in complex with 1,2,4 Dimer
分子名称: 5,5'-(ethane-1,2-diylbis(oxy))bis(benzene-5,4,2,1,-tetrayl)hexakisphosphate, Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2
著者Whitfield, H, Brearley, C.A, Hemmings, A.M.
登録日2019-09-04
公開日2021-01-13
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Allosteric Site on SHIP2 Identified Through Fluorescent Ligand Screening and Crystallography: A Potential New Target for Intervention.
J.Med.Chem., 64, 2021

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件を2024-06-12に公開中

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