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PDB: 3 件

7TI1
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BU of 7ti1 by Molmil
Structure of AmpC bound to RPX-7063 at 2.0A
分子名称: 1,2-ETHANEDIOL, Beta-lactamase, CHLORIDE ION, ...
著者Clifton, M.C, Abendroth, J, Edwards, T.E, Hecker, S.J.
登録日2022-01-12
公開日2023-01-25
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Broad-spectrum cyclic boronate beta-lactamase inhibitors featuring an intramolecular prodrug for oral bioavailability.
Bioorg.Med.Chem., 62, 2022
7TI2
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BU of 7ti2 by Molmil
Structure of KPC-2 bound to RPX-7063 at 1.75A
分子名称: 1,2-ETHANEDIOL, Carbapenem-hydrolyzing beta-lactamase KPC, {(3R,7S)-2-hydroxy-3-[2-(thiophen-2-yl)acetamido]-2,3,4,7-tetrahydro-1,2-oxaborepin-7-yl}acetic acid
著者Clifton, M.C, Fairman, J.W, Edwards, T.E, Hecker, S.J.
登録日2022-01-12
公開日2022-10-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Broad-spectrum cyclic boronate beta-lactamase inhibitors featuring an intramolecular prodrug for oral bioavailability.
Bioorg.Med.Chem., 62, 2022
7TI0
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BU of 7ti0 by Molmil
Structure of CTX-M-15 bound to RPX-7063 at 1.5A
分子名称: 1,2-ETHANEDIOL, Beta-lactamase, CHLORIDE ION, ...
著者Clifton, M.C, Abendroth, J, Hecker, S.J, Edwards, T.E.
登録日2022-01-12
公開日2022-05-18
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Broad-spectrum cyclic boronate beta-lactamase inhibitors featuring an intramolecular prodrug for oral bioavailability.
Bioorg.Med.Chem., 62, 2022

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件を2024-07-24に公開中

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