7UBZ
 
 | | Chymotrypsin digested toxin/immunity complex for a T6SS lipase effector from E. cloacae | | 分子名称: | Ankyrin repeat domain-containing protein, CITRATE ANION, GLYCEROL, ... | | 著者 | Cuthbert, B.J, Jensen, S.J, Goulding, C.W, Hayes, C.S. | | 登録日 | 2022-03-15 | | 公開日 | 2022-08-24 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Toxin/immunity complex for a T6SS lipase effector from E. cloacae
To Be Published
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7M5F
 | | Contact-dependent inhibition system from Serratia marcescens BWH57 | | 分子名称: | CdiI, MALONATE ION, Toxin CdiA | | 著者 | Michalska, K, Nutt, W, Stols, L, Jedrzejczak, R, Hayes, C.S, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2021-03-23 | | 公開日 | 2021-05-12 | | 最終更新日 | 2021-08-18 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Contact-dependent inhibition system from Serratia marcescens
To Be Published
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4Q7O
 | | The crystal structure of an immunity protein NMB0503 from Neisseria meningitidis MC58 | | 分子名称: | BROMIDE ION, FORMIC ACID, Immunity protein | | 著者 | Tan, K, Stols, L, Eschenfeldt, W, Babnigg, G, Low, D.A, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) | | 登録日 | 2014-04-25 | | 公開日 | 2014-05-14 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | The structure of a contact-dependent growth-inhibition (CDI) immunity protein from Neisseria meningitidis MC58.
Acta Crystallogr F Struct Biol Commun, 71, 2015
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6CP9
 | | Contact-dependent growth inhibition toxin - immunity protein complex from Klebsiella pneumoniae 342 | | 分子名称: | CdiA, CdiI | | 著者 | Michalska, K, Stols, L, Eschenfeldt, W, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) | | 登録日 | 2018-03-13 | | 公開日 | 2019-03-13 | | 最終更新日 | 2020-01-01 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Convergent Evolution of the Barnase/EndoU/Colicin/RelE (BECR) Fold in Antibacterial tRNase Toxins.
Structure, 27, 2019
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8EY4
 | | Contact-dependent growth inhibition toxin-immunity protein complex from E. coli O32:H37 | | 分子名称: | Cys_rich_CPCC domain-containing protein, FE (III) ION, PT-VENN domain-containing protein | | 著者 | Michalska, K, Stols, L, Eschenfeldt, W, Goulding, C.W, Hayes, C.S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2022-10-26 | | 公開日 | 2023-11-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | Contact-dependent growth inhibition toxin-immunity protein complex from E. coli O32:H37
To Be Published
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8EY3
 | | Contact-dependent growth inhibition (CDI) immunity protein from E. coli O32:H37 | | 分子名称: | Cys_rich_CPCC domain-containing protein, FE (III) ION, SODIUM ION | | 著者 | Michalska, K, Stols, L, Eschenfeldt, W, Goulding, C.W, Hayes, C.S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2022-10-26 | | 公開日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Contact-dependent growth inhibition (CDI) immunity protein from E. coli O32:H37
To Be Published
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4G6V
 | | CdiA-CT/CdiI toxin and immunity complex from Burkholderia pseudomallei | | 分子名称: | Adhesin/hemolysin, BROMIDE ION, CdiI | | 著者 | Morse, R.P, Nikolakakis, K, Willet, J, Gerrick, E, Low, D.A, Hayes, C.S, Goulding, C.W. | | 登録日 | 2012-07-19 | | 公開日 | 2012-12-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Structural basis of toxicity and immunity in contact-dependent growth inhibition (CDI) systems.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4G6U
 | | CdiA-CT/CdiI toxin and immunity complex from Escherichia coli | | 分子名称: | ACETATE ION, CHLORIDE ION, EC869 CdiA-CT, ... | | 著者 | Morse, R.P, Nikolakakis, K, Willet, J, Gerrick, E, Low, D.A, Hayes, C.S, Goulding, C.W. | | 登録日 | 2012-07-19 | | 公開日 | 2012-12-12 | | 最終更新日 | 2017-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.353 Å) | | 主引用文献 | Structural basis of toxicity and immunity in contact-dependent growth inhibition (CDI) systems.
Proc.Natl.Acad.Sci.USA, 109, 2012
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5T87
 | | Crystal structure of CDI complex from Cupriavidus taiwanensis LMG 19424 | | 分子名称: | CdiA toxin, CdiI immunity protein | | 著者 | Michalska, K, Joachimiak, G, Jedrzejczak, R, Hayes, C.S, Goulding, C.W, Joachimiak, A, Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI), Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2016-09-06 | | 公開日 | 2017-09-13 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016).
Proteins, 86 Suppl 1, 2018
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5T86
 | | Crystal structure of CDI complex from E. coli A0 34/86 | | 分子名称: | ACETATE ION, CdiA toxin, CdiI immunity protein | | 著者 | Michalska, K, Stols, L, Jedrzejczak, R, Hayes, C.S, Goulding, C.W, Joachimiak, A, Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI), Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2016-09-06 | | 公開日 | 2017-09-13 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of CDI complex from E. coli A0 34/86
To Be Published
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5I4R
 | | Contact-dependent inhibition system from Escherichia coli NC101 - ternary CdiA/CdiI/EF-Tu complex (trypsin-modified) | | 分子名称: | Contact-dependent inhibitor A, Contact-dependent inhibitor I, Elongation factor Tu, ... | | 著者 | Michalska, K, Stols, L, Eschenfeldt, W, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) | | 登録日 | 2016-02-12 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Structure of a novel antibacterial toxin that exploits elongation factor Tu to cleave specific transfer RNAs.
Nucleic Acids Res., 45, 2017
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6CP8
 | | Contact-dependent growth inhibition toxin-immunity protein complex from from E. coli 3006 | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CdiA, CdiI, ... | | 著者 | Michalska, K, Stols, L, Eschenfeldt, W, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) | | 登録日 | 2018-03-13 | | 公開日 | 2019-03-13 | | 最終更新日 | 2020-01-01 | | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | | 主引用文献 | Convergent Evolution of the Barnase/EndoU/Colicin/RelE (BECR) Fold in Antibacterial tRNase Toxins.
Structure, 27, 2019
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5I4Q
 | | Contact-dependent inhibition system from Escherichia coli NC101 - ternary CdiA/CdiI/EF-Tu complex (domains 2 and 3) | | 分子名称: | CHLORIDE ION, Contact-dependent inhibitor A, Contact-dependent inhibitor I, ... | | 著者 | Michalska, K, Stols, L, Eschenfeldt, W, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) | | 登録日 | 2016-02-12 | | 公開日 | 2017-06-28 | | 最終更新日 | 2019-12-25 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Structure of a novel antibacterial toxin that exploits elongation factor Tu to cleave specific transfer RNAs.
Nucleic Acids Res., 45, 2017
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6VEK
 | | Contact-dependent growth inhibition toxin-immunity protein complex from from E. coli 3006, full-length | | 分子名称: | contact-dependent immunity protein CdiI, contact-dependent toxin CdiA | | 著者 | Michalska, K, Stols, L, Eschenfeldt, W, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI), Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2020-01-02 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Contact-dependent growth inhibition toxin-immunity protein complex from from E. coli 3006, full-length
To Be Published
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6GT3
 | | Crystal Structure of the A2A-StaR2-bRIL562 in complex with AZD4635 at 2.0A resolution | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 6-(2-chloranyl-6-methyl-pyridin-4-yl)-5-(4-fluorophenyl)-1,2,4-triazin-3-amine, Adenosine receptor A2a,Soluble cytochrome b562,Adenosine receptor A2a, ... | | 著者 | Borodovsky, A, Wang, Y, Deng, N, Ye, M, Stephen, T.L, Goodwin, K, Goodwin, R, Strittmatter, N, Shaw, J, Sachsenmeier, K, Clarke, J.D, Hay, C, Reimer, C, Andrews, S.P, Brown, G.A, Congreve, M, Cheng, R.K.Y, Dore, A.S, Mason, J.S, Marshall, F.H, Weir, M.P, Lyne, P, Woessner, R. | | 登録日 | 2018-06-15 | | 公開日 | 2019-06-26 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Small molecule AZD4635 inhibitor of A2AR signaling rescues immune cell function including CD103+ dendritic cells enhancing anti-tumor immunity
J Immunother Cancer, 2020
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