5J8G
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![BU of 5j8g by Molmil](/molmil-images/mine/5j8g) | Structure of nitroreductase from E. cloacae complexed with para-nitrobenzoic acid | 分子名称: | 4-NITROBENZOIC ACID, FLAVIN MONONUCLEOTIDE, Oxygen-insensitive NAD(P)H nitroreductase | 著者 | Haynes, C.A, Koder, R.L, Miller, A.-F, Rodgers, D.W. | 登録日 | 2016-04-07 | 公開日 | 2017-05-17 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mechanism-Informed Refinement Reveals Altered Substrate-Binding Mode for Catalytically Competent Nitroreductase. Structure, 25, 2017
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5J8D
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![BU of 5j8d by Molmil](/molmil-images/mine/5j8d) | Structure of nitroreductase from E. cloacae complexed with nicotinic acid adenine dinucleotide | 分子名称: | FLAVIN MONONUCLEOTIDE, NICOTINIC ACID ADENINE DINUCLEOTIDE, Oxygen-insensitive NAD(P)H nitroreductase | 著者 | Haynes, C.A, Koder, R.L, Miller, A.F, Rodgers, D.W. | 登録日 | 2016-04-07 | 公開日 | 2017-05-17 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Mechanism-Informed Refinement Reveals Altered Substrate-Binding Mode for Catalytically Competent Nitroreductase. Structure, 25, 2017
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1KQD
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![BU of 1kqd by Molmil](/molmil-images/mine/1kqd) | Structure of Nitroreductase from E. cloacae Bound with 2e-Reduced Flavin Mononucleotide (FMN) | 分子名称: | FLAVIN MONONUCLEOTIDE, OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE | 著者 | Haynes, C.A, Koder, R.L, Miller, A.F, Rodgers, D.W. | 登録日 | 2002-01-04 | 公開日 | 2002-02-13 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structures of nitroreductase in three states: effects of inhibitor binding and reduction. J.Biol.Chem., 277, 2002
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1KQB
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![BU of 1kqb by Molmil](/molmil-images/mine/1kqb) | Structure of Nitroreductase from E. cloacae complex with inhibitor benzoate | 分子名称: | BENZOIC ACID, FLAVIN MONONUCLEOTIDE, OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE | 著者 | Haynes, C.A, Koder, R.L, Miller, A.F, Rodgers, D.W. | 登録日 | 2002-01-04 | 公開日 | 2002-02-13 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structures of nitroreductase in three states: effects of inhibitor binding and reduction. J.Biol.Chem., 277, 2002
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1KQC
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![BU of 1kqc by Molmil](/molmil-images/mine/1kqc) | Structure of Nitroreductase from E. cloacae Complex with Inhibitor Acetate | 分子名称: | ACETATE ION, FLAVIN MONONUCLEOTIDE, OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE | 著者 | Haynes, C.A, Koder, R.L, Miller, A.F, Rodgers, D.W. | 登録日 | 2002-01-04 | 公開日 | 2002-02-13 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structures of nitroreductase in three states: effects of inhibitor binding and reduction. J.Biol.Chem., 277, 2002
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5I4Q
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![BU of 5i4q by Molmil](/molmil-images/mine/5i4q) | Contact-dependent inhibition system from Escherichia coli NC101 - ternary CdiA/CdiI/EF-Tu complex (domains 2 and 3) | 分子名称: | CHLORIDE ION, Contact-dependent inhibitor A, Contact-dependent inhibitor I, ... | 著者 | Michalska, K, Stols, L, Eschenfeldt, W, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) | 登録日 | 2016-02-12 | 公開日 | 2017-06-28 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structure of a novel antibacterial toxin that exploits elongation factor Tu to cleave specific transfer RNAs. Nucleic Acids Res., 45, 2017
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6GT3
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![BU of 6gt3 by Molmil](/molmil-images/mine/6gt3) | Crystal Structure of the A2A-StaR2-bRIL562 in complex with AZD4635 at 2.0A resolution | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 6-(2-chloranyl-6-methyl-pyridin-4-yl)-5-(4-fluorophenyl)-1,2,4-triazin-3-amine, Adenosine receptor A2a,Soluble cytochrome b562,Adenosine receptor A2a, ... | 著者 | Borodovsky, A, Wang, Y, Deng, N, Ye, M, Stephen, T.L, Goodwin, K, Goodwin, R, Strittmatter, N, Shaw, J, Sachsenmeier, K, Clarke, J.D, Hay, C, Reimer, C, Andrews, S.P, Brown, G.A, Congreve, M, Cheng, R.K.Y, Dore, A.S, Mason, J.S, Marshall, F.H, Weir, M.P, Lyne, P, Woessner, R. | 登録日 | 2018-06-15 | 公開日 | 2019-06-26 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Small molecule AZD4635 inhibitor of A2AR signaling rescues immune cell function including CD103+ dendritic cells enhancing anti-tumor immunity J Immunother Cancer, 2020
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5I4R
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![BU of 5i4r by Molmil](/molmil-images/mine/5i4r) | Contact-dependent inhibition system from Escherichia coli NC101 - ternary CdiA/CdiI/EF-Tu complex (trypsin-modified) | 分子名称: | Contact-dependent inhibitor A, Contact-dependent inhibitor I, Elongation factor Tu, ... | 著者 | Michalska, K, Stols, L, Eschenfeldt, W, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) | 登録日 | 2016-02-12 | 公開日 | 2017-06-28 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Structure of a novel antibacterial toxin that exploits elongation factor Tu to cleave specific transfer RNAs. Nucleic Acids Res., 45, 2017
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6CP9
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![BU of 6cp9 by Molmil](/molmil-images/mine/6cp9) | Contact-dependent growth inhibition toxin - immunity protein complex from Klebsiella pneumoniae 342 | 分子名称: | CdiA, CdiI | 著者 | Michalska, K, Stols, L, Eschenfeldt, W, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) | 登録日 | 2018-03-13 | 公開日 | 2019-03-13 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Convergent Evolution of the Barnase/EndoU/Colicin/RelE (BECR) Fold in Antibacterial tRNase Toxins. Structure, 27, 2019
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6CP8
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![BU of 6cp8 by Molmil](/molmil-images/mine/6cp8) | Contact-dependent growth inhibition toxin-immunity protein complex from from E. coli 3006 | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CdiA, CdiI, ... | 著者 | Michalska, K, Stols, L, Eschenfeldt, W, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) | 登録日 | 2018-03-13 | 公開日 | 2019-03-13 | 最終更新日 | 2020-01-01 | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | 主引用文献 | Convergent Evolution of the Barnase/EndoU/Colicin/RelE (BECR) Fold in Antibacterial tRNase Toxins. Structure, 27, 2019
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8SSK
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![BU of 8ssk by Molmil](/molmil-images/mine/8ssk) | Citrobacter rodentium contact dependent growth inhibition (CDI) entry and toxin (CdiA-CT) domains | 分子名称: | ACETATE ION, CALCIUM ION, Contact-dependent inhibitor A, ... | 著者 | Cuthbert, B.J, Goulding, C.W, Hayes, C.S, Nhan, D.Q. | 登録日 | 2023-05-08 | 公開日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Citrobacter rodentium contact dependent growth inhibition (CDI) entry and toxin (CdiA-CT) domains To Be Published
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4Q7O
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![BU of 4q7o by Molmil](/molmil-images/mine/4q7o) | The crystal structure of an immunity protein NMB0503 from Neisseria meningitidis MC58 | 分子名称: | BROMIDE ION, FORMIC ACID, Immunity protein | 著者 | Tan, K, Stols, L, Eschenfeldt, W, Babnigg, G, Low, D.A, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI) | 登録日 | 2014-04-25 | 公開日 | 2014-05-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | The structure of a contact-dependent growth-inhibition (CDI) immunity protein from Neisseria meningitidis MC58. Acta Crystallogr F Struct Biol Commun, 71, 2015
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8SSM
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![BU of 8ssm by Molmil](/molmil-images/mine/8ssm) | |
8SX0
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![BU of 8sx0 by Molmil](/molmil-images/mine/8sx0) | Bordetella filamentous hemagglutinin (FhaB) C-terminal domain | 分子名称: | CALCIUM ION, Filamentous hemagglutinin, GLYCEROL, ... | 著者 | Cuthbert, B.J, Goulding, C.W, Hayes, C.S, Costello, M.S. | 登録日 | 2023-05-19 | 公開日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Bordetella filamentous hemagglutinin (FhaB) C-terminal domain To Be Published
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8EY4
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![BU of 8ey4 by Molmil](/molmil-images/mine/8ey4) | Contact-dependent growth inhibition toxin-immunity protein complex from E. coli O32:H37 | 分子名称: | Cys_rich_CPCC domain-containing protein, FE (III) ION, PT-VENN domain-containing protein | 著者 | Michalska, K, Stols, L, Eschenfeldt, W, Goulding, C.W, Hayes, C.S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2022-10-26 | 公開日 | 2023-11-08 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Contact-dependent growth inhibition toxin-immunity protein complex from E. coli O32:H37 To Be Published
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6VEK
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![BU of 6vek by Molmil](/molmil-images/mine/6vek) | Contact-dependent growth inhibition toxin-immunity protein complex from from E. coli 3006, full-length | 分子名称: | contact-dependent immunity protein CdiI, contact-dependent toxin CdiA | 著者 | Michalska, K, Stols, L, Eschenfeldt, W, Hayes, C.S, Goulding, C.W, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI), Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-01-02 | 公開日 | 2021-01-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Contact-dependent growth inhibition toxin-immunity protein complex from from E. coli 3006, full-length To Be Published
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8EY3
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![BU of 8ey3 by Molmil](/molmil-images/mine/8ey3) | Contact-dependent growth inhibition (CDI) immunity protein from E. coli O32:H37 | 分子名称: | Cys_rich_CPCC domain-containing protein, FE (III) ION, SODIUM ION | 著者 | Michalska, K, Stols, L, Eschenfeldt, W, Goulding, C.W, Hayes, C.S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2022-10-26 | 公開日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1 Å) | 主引用文献 | Contact-dependent growth inhibition (CDI) immunity protein from E. coli O32:H37 To Be Published
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5T87
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![BU of 5t87 by Molmil](/molmil-images/mine/5t87) | Crystal structure of CDI complex from Cupriavidus taiwanensis LMG 19424 | 分子名称: | CdiA toxin, CdiI immunity protein | 著者 | Michalska, K, Joachimiak, G, Jedrzejczak, R, Hayes, C.S, Goulding, C.W, Joachimiak, A, Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI), Midwest Center for Structural Genomics (MCSG) | 登録日 | 2016-09-06 | 公開日 | 2017-09-13 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Target highlights from the first post-PSI CASP experiment (CASP12, May-August 2016). Proteins, 86 Suppl 1, 2018
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7M5F
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![BU of 7m5f by Molmil](/molmil-images/mine/7m5f) | Contact-dependent inhibition system from Serratia marcescens BWH57 | 分子名称: | CdiI, MALONATE ION, Toxin CdiA | 著者 | Michalska, K, Nutt, W, Stols, L, Jedrzejczak, R, Hayes, C.S, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2021-03-23 | 公開日 | 2021-05-12 | 最終更新日 | 2021-08-18 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Contact-dependent inhibition system from Serratia marcescens To Be Published
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5T86
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![BU of 5t86 by Molmil](/molmil-images/mine/5t86) | Crystal structure of CDI complex from E. coli A0 34/86 | 分子名称: | ACETATE ION, CdiA toxin, CdiI immunity protein | 著者 | Michalska, K, Stols, L, Jedrzejczak, R, Hayes, C.S, Goulding, C.W, Joachimiak, A, Structure-Function Analysis of Polymorphic CDI Toxin-Immunity Protein Complexes (UC4CDI), Midwest Center for Structural Genomics (MCSG) | 登録日 | 2016-09-06 | 公開日 | 2017-09-13 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of CDI complex from E. coli A0 34/86 To Be Published
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4G6V
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![BU of 4g6v by Molmil](/molmil-images/mine/4g6v) | CdiA-CT/CdiI toxin and immunity complex from Burkholderia pseudomallei | 分子名称: | Adhesin/hemolysin, BROMIDE ION, CdiI | 著者 | Morse, R.P, Nikolakakis, K, Willet, J, Gerrick, E, Low, D.A, Hayes, C.S, Goulding, C.W. | 登録日 | 2012-07-19 | 公開日 | 2012-12-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | Structural basis of toxicity and immunity in contact-dependent growth inhibition (CDI) systems. Proc.Natl.Acad.Sci.USA, 109, 2012
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4G6U
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![BU of 4g6u by Molmil](/molmil-images/mine/4g6u) | CdiA-CT/CdiI toxin and immunity complex from Escherichia coli | 分子名称: | ACETATE ION, CHLORIDE ION, EC869 CdiA-CT, ... | 著者 | Morse, R.P, Nikolakakis, K, Willet, J, Gerrick, E, Low, D.A, Hayes, C.S, Goulding, C.W. | 登録日 | 2012-07-19 | 公開日 | 2012-12-12 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.353 Å) | 主引用文献 | Structural basis of toxicity and immunity in contact-dependent growth inhibition (CDI) systems. Proc.Natl.Acad.Sci.USA, 109, 2012
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7UBZ
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![BU of 7ubz by Molmil](/molmil-images/mine/7ubz) | Chymotrypsin digested toxin/immunity complex for a T6SS lipase effector from E. cloacae | 分子名称: | Ankyrin repeat domain-containing protein, CITRATE ANION, GLYCEROL, ... | 著者 | Cuthbert, B.J, Jensen, S.J, Goulding, C.W, Hayes, C.S. | 登録日 | 2022-03-15 | 公開日 | 2022-08-24 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Toxin/immunity complex for a T6SS lipase effector from E. cloacae To Be Published
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1F00
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![BU of 1f00 by Molmil](/molmil-images/mine/1f00) | CRYSTAL STRUCTURE OF C-TERMINAL 282-RESIDUE FRAGMENT OF ENTEROPATHOGENIC E. COLI INTIMIN | 分子名称: | INTIMIN | 著者 | Luo, Y, Frey, E.A, Pfuetzner, R.A, Creagh, A.L, Knoechel, D.G, Haynes, C.A, Finlay, B.B, Strynadka, N.C.J. | 登録日 | 2000-05-12 | 公開日 | 2000-07-12 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of enteropathogenic Escherichia coli intimin-receptor complex. Nature, 405, 2000
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1F02
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![BU of 1f02 by Molmil](/molmil-images/mine/1f02) | CRYSTAL STRUCTURE OF C-TERMINAL 282-RESIDUE FRAGMENT OF INTIMIN IN COMPLEX WITH TRANSLOCATED INTIMIN RECEPTOR (TIR) INTIMIN-BINDING DOMAIN | 分子名称: | INTIMIN, TRANSLOCATED INTIMIN RECEPTOR | 著者 | Luo, Y, Frey, E.A, Pfuetzner, R.A, Creagh, A.L, Knoechel, D.G, Haynes, C.A, Finlay, B.B, Strynadka, N.C.J. | 登録日 | 2000-05-14 | 公開日 | 2000-07-12 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structure of enteropathogenic Escherichia coli intimin-receptor complex. Nature, 405, 2000
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