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PDB: 94 results

8DCP
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BU of 8dcp by Molmil
PI 3-kinase alpha with nanobody 3-126
Descriptor: Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Authors:Hart, J.R, Liu, X, Pan, C, Liang, A, Ueno, L, Xu, Y, Quezada, A, Zou, X, Yang, S, Zhou, Q, Schoonooghe, S, Hassanzadeh-Ghassabeh, G, Xia, T, Shui, W, Yang, D, Vogt, P.K, Wang, M.-W.
Deposit date:2022-06-17
Release date:2022-09-21
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.41 Å)
Cite:Nanobodies and chemical cross-links advance the structural and functional analysis of PI3K alpha.
Proc.Natl.Acad.Sci.USA, 119, 2022
8DD4
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BU of 8dd4 by Molmil
PI 3-kinase alpha with nanobody 3-142
Descriptor: Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Authors:Hart, J.R, Liu, X, Pan, C, Liang, A, Ueno, L, Xu, Y, Quezada, A, Zou, X, Yang, S, Zhou, Q, Schoonooghe, S, Hassanzadeh-Ghassabeh, G, Xia, T, Shui, W, Yang, D, Vogt, P.K, Wang, M.-W.
Deposit date:2022-06-17
Release date:2022-09-21
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Nanobodies and chemical cross-links advance the structural and functional analysis of PI3K alpha.
Proc.Natl.Acad.Sci.USA, 119, 2022
8DD8
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BU of 8dd8 by Molmil
PI 3-kinase alpha with nanobody 3-142, crosslinked with DSG
Descriptor: Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Authors:Hart, J.R, Liu, X, Pan, C, Liang, A, Ueno, L, Xu, Y, Quezada, A, Zou, X, Yang, S, Zhou, Q, Schoonooghe, S, Hassanzadeh-Ghassabeh, G, Xia, T, Shui, W, Yang, D, Vogt, P.K, Wang, M.-W.
Deposit date:2022-06-17
Release date:2022-09-21
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Nanobodies and chemical cross-links advance the structural and functional analysis of PI3K alpha.
Proc.Natl.Acad.Sci.USA, 119, 2022
8DCX
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BU of 8dcx by Molmil
PI 3-kinase alpha with nanobody 3-159
Descriptor: Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Authors:Hart, J.R, Liu, X, Pan, C, Liang, A, Ueno, L, Xu, Y, Quezada, A, Zou, X, Yang, S, Zhou, Q, Schoonooghe, S, Hassanzadeh-Ghassabeh, G, Xia, T, Shui, W, Yang, D, Vogt, P.K, Wang, M.-W.
Deposit date:2022-06-17
Release date:2022-09-21
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Nanobodies and chemical cross-links advance the structural and functional analysis of PI3K alpha.
Proc.Natl.Acad.Sci.USA, 119, 2022
3SZ7
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BU of 3sz7 by Molmil
Crystal structure of the Sgt2 TPR domain from Aspergillus fumigatus
Descriptor: Hsc70 cochaperone (SGT)
Authors:Chartron, J.W, Gonzalez, G.M, Clemons Jr, W.M.
Deposit date:2011-07-18
Release date:2011-08-10
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.72 Å)
Cite:A structural model of the Sgt2 protein and its interactions with chaperones and the Get4/Get5 complex.
J.Biol.Chem., 286, 2011
6QGX
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BU of 6qgx by Molmil
Crystal structure of E.coli BamA beta-barrel in complex with nanobody F7
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, NanoF7, Outer membrane protein assembly factor BamA
Authors:Hartmann, J.-B, Kaur, H, Jakob, R.P, Zahn, M, Zimmermann, I, Seeger, M, Maier, T, Hiller, S.
Deposit date:2019-01-14
Release date:2019-06-26
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Identification of conformation-selective nanobodies against the membrane protein insertase BamA by an integrated structural biology approach.
J.Biomol.Nmr, 73, 2019
6QGY
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BU of 6qgy by Molmil
Crystal structure of E.coli BamA beta-barrel in complex with nanobody B12
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, NanoB12, Outer membrane protein assembly factor BamA
Authors:Hartmann, J.-B, Kaur, H, Jakob, R.P, Zahn, M, Zimmermann, I, Seeger, M, Maier, T, Hiller, S.
Deposit date:2019-01-14
Release date:2019-06-26
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.509 Å)
Cite:Identification of conformation-selective nanobodies against the membrane protein insertase BamA by an integrated structural biology approach.
J.Biomol.Nmr, 73, 2019
6QGW
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BU of 6qgw by Molmil
Crystal structure of E.coli BamA beta-barrel in complex with nanobody E6
Descriptor: (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, NanoE6, Outer membrane protein assembly factor BamA
Authors:Hartmann, J.-B, Kaur, H, Jakob, R.P, Zahn, M, Zimmermann, I, Seeger, M, Maier, T, Hiller, S.
Deposit date:2019-01-14
Release date:2019-06-26
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.938 Å)
Cite:Identification of conformation-selective nanobodies against the membrane protein insertase BamA by an integrated structural biology approach.
J.Biomol.Nmr, 73, 2019
3LKU
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BU of 3lku by Molmil
Crystal structure of S. cerevisiae Get4 in complex with an N-terminal fragment of Get5
Descriptor: PROLINE, UPF0363 protein YOR164C, Ubiquitin-like protein MDY2
Authors:Chartron, J.W, Clemons Jr, W.M.
Deposit date:2010-01-27
Release date:2010-06-23
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural characterization of the Get4/Get5 complex and its interaction with Get3.
Proc.Natl.Acad.Sci.USA, 107, 2010
3VEJ
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BU of 3vej by Molmil
Crystal structure of the Get5 carboxyl domain from S. cerevisiae
Descriptor: PHOSPHATE ION, Ubiquitin-like protein MDY2
Authors:Chartron, J.W, Vandervelde, D.G, Rao, M, Clemons Jr, W.M.
Deposit date:2012-01-08
Release date:2012-01-25
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.23 Å)
Cite:Get5 Carboxyl-terminal Domain Is a Novel Dimerization Motif That Tethers an Extended Get4/Get5 Complex.
J.Biol.Chem., 287, 2012
3PSG
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BU of 3psg by Molmil
THE HIGH RESOLUTION CRYSTAL STRUCTURE OF PORCINE PEPSINOGEN
Descriptor: PEPSINOGEN
Authors:Hartsuck, J.A, Koelsch, G, Remington, S.J.
Deposit date:1991-09-03
Release date:1993-01-15
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:The high-resolution crystal structure of porcine pepsinogen.
Proteins, 13, 1992
2GOY
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BU of 2goy by Molmil
Crystal structure of assimilatory adenosine 5'-phosphosulfate reductase with bound APS
Descriptor: ADENOSINE-5'-PHOSPHOSULFATE, IRON/SULFUR CLUSTER, adenosine phosphosulfate reductase
Authors:Chartron, J, Carroll, K.S, Shiau, C, Gao, H, Leary, J.A, Bertozzi, C.R, Stout, C.D.
Deposit date:2006-04-14
Release date:2006-09-19
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Substrate Recognition, Protein Dynamics, and Iron-Sulfur Cluster in Pseudomonas aeruginosa Adenosine 5'-Phosphosulfate Reductase.
J.Mol.Biol., 364, 2006
2LNZ
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BU of 2lnz by Molmil
Solution structure of the Get5 carboxyl domain from S. cerevisiae
Descriptor: Ubiquitin-like protein MDY2
Authors:Chartron, J.W, Vandervelde, D.G, Rao, M, Clemons Jr, W.M.
Deposit date:2012-01-08
Release date:2012-01-25
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Get5 Carboxyl-terminal Domain Is a Novel Dimerization Motif That Tethers an Extended Get4/Get5 Complex.
J.Biol.Chem., 287, 2012
4GOC
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BU of 4goc by Molmil
Crystal structure of the Get5 ubiquitin-like domain
Descriptor: Golgi to ER traffic protein 5
Authors:Chartron, J.W, VanderVelde, D.G, Clemons Jr, W.M.
Deposit date:2012-08-19
Release date:2012-11-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of the Sgt2/SGTA Dimerization Domain with the Get5/UBL4A UBL Domain Reveal an Interaction that Forms a Conserved Dynamic Interface.
Cell Rep, 2, 2012
4GOE
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BU of 4goe by Molmil
Crystal structure of the SGTA homodimerization domain with a covalent modification of a single C38
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, Small glutamine-rich tetratricopeptide repeat-containing protein alpha
Authors:Chartron, J.W, VanderVelde, D.G, Clemons Jr, W.M.
Deposit date:2012-08-19
Release date:2012-11-21
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Structures of the Sgt2/SGTA Dimerization Domain with the Get5/UBL4A UBL Domain Reveal an Interaction that Forms a Conserved Dynamic Interface.
Cell Rep, 2, 2012
4GOF
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BU of 4gof by Molmil
Crystal structure of the SGTA homodimerization domain with covalent modifications to both C38
Descriptor: BETA-MERCAPTOETHANOL, CHLORIDE ION, Small glutamine-rich tetratricopeptide repeat-containing protein alpha
Authors:Chartron, J.W, VanderVelde, D.G, Clemons Jr, W.M.
Deposit date:2012-08-19
Release date:2012-11-21
Last modified:2013-01-16
Method:X-RAY DIFFRACTION (1.35 Å)
Cite:Structures of the Sgt2/SGTA Dimerization Domain with the Get5/UBL4A UBL Domain Reveal an Interaction that Forms a Conserved Dynamic Interface.
Cell Rep, 2, 2012
4GOD
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BU of 4god by Molmil
Crystal structure of the SGTA homodimerization domain
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Small glutamine-rich tetratricopeptide repeat-containing protein alpha
Authors:Chartron, J.W, VanderVelde, D.G, Clemons Jr, W.M.
Deposit date:2012-08-19
Release date:2012-11-21
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structures of the Sgt2/SGTA Dimerization Domain with the Get5/UBL4A UBL Domain Reveal an Interaction that Forms a Conserved Dynamic Interface.
Cell Rep, 2, 2012
2OG2
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BU of 2og2 by Molmil
Crystal structure of chloroplast FtsY from Arabidopsis thaliana
Descriptor: MAGNESIUM ION, MALONATE ION, Putative signal recognition particle receptor
Authors:Chartron, J, Chandrasekar, S, Ampornpan, P.J, Shan, S.
Deposit date:2007-01-04
Release date:2007-12-11
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of the Chloroplast Signal Recognition Particle (SRP) Receptor: Domain Arrangement Modulates SRP-Receptor Interaction.
J.Mol.Biol., 375, 2007
2LO0
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BU of 2lo0 by Molmil
Solution structure of the Get5 carboxyl domain from A. fumigatus
Descriptor: Uncharacterized protein
Authors:Chartron, J.W, Vandervelde, D.G, Rao, M, Clemons Jr, W.M.
Deposit date:2012-01-08
Release date:2012-01-25
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Get5 Carboxyl-terminal Domain Is a Novel Dimerization Motif That Tethers an Extended Get4/Get5 Complex.
J.Biol.Chem., 287, 2012
2LXA
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BU of 2lxa by Molmil
Solution structure of the Get5 ubiquitin-like domain
Descriptor: Ubiquitin-like protein MDY2
Authors:Chartron, J.W, Vandervelde, D.G, Clemons Jr, W.M.
Deposit date:2012-08-19
Release date:2012-11-21
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structures of the Sgt2/SGTA Dimerization Domain with the Get5/UBL4A UBL Domain Reveal an Interaction that Forms a Conserved Dynamic Interface.
Cell Rep, 2, 2012
2LXB
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BU of 2lxb by Molmil
Solution structure of the Sgt2 homodimerization domain
Descriptor: Small glutamine-rich tetratricopeptide repeat-containing protein 2
Authors:Chartron, J.W, Vandervelde, D.G, Clemons Jr, W.M.
Deposit date:2012-08-19
Release date:2012-11-21
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structures of the Sgt2/SGTA Dimerization Domain with the Get5/UBL4A UBL Domain Reveal an Interaction that Forms a Conserved Dynamic Interface.
Cell Rep, 2, 2012
2LXC
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BU of 2lxc by Molmil
Solution structure of the complex between the Sgt2 homodimerization domain and the Get5 UBL domain
Descriptor: Small glutamine-rich tetratricopeptide repeat-containing protein 2, Ubiquitin-like protein MDY2
Authors:Chartron, J.W, Vandervelde, D.G, Clemons Jr, W.M.
Deposit date:2012-08-19
Release date:2012-11-21
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structures of the Sgt2/SGTA Dimerization Domain with the Get5/UBL4A UBL Domain Reveal an Interaction that Forms a Conserved Dynamic Interface.
Cell Rep, 2, 2012
2O8V
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BU of 2o8v by Molmil
PAPS reductase in a covalent complex with thioredoxin C35A
Descriptor: Phosphoadenosine phosphosulfate reductase, Thioredoxin 1
Authors:Chartron, J, Shiau, C, Stout, C.D, Carroll, K.S.
Deposit date:2006-12-12
Release date:2007-03-27
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (3 Å)
Cite:3'-Phosphoadenosine-5'-phosphosulfate Reductase in Complex with Thioredoxin: A Structural Snapshot in the Catalytic Cycle.
Biochemistry, 46, 2007
8GUB
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BU of 8gub by Molmil
Cryo-EM structure of cancer-specific PI3Kalpha mutant H1047R in complex with BYL-719
Descriptor: (2S)-N~1~-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Authors:Liu, X, Zhou, Q, Hart, J.R, Xu, Y, Yang, S, Yang, D, Vogt, P.K, Wang, M.-W.
Deposit date:2022-09-11
Release date:2022-11-23
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.73 Å)
Cite:Cryo-EM structures of cancer-specific helical and kinase domain mutations of PI3K alpha.
Proc.Natl.Acad.Sci.USA, 119, 2022
8GUD
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BU of 8gud by Molmil
Cryo-EM structure of cancer-specific PI3Kalpha mutant E545K in complex with BYL-719
Descriptor: (2S)-N~1~-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Authors:Liu, X, Zhou, Q, Hart, J.R, Xu, Y, Yang, S, Yang, D, Vogt, P.K, Wang, M.-W.
Deposit date:2022-09-11
Release date:2022-11-23
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.62 Å)
Cite:Cryo-EM structures of cancer-specific helical and kinase domain mutations of PI3K alpha.
Proc.Natl.Acad.Sci.USA, 119, 2022

 

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數據於2024-11-20公開中

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