1Y4Y
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![BU of 1y4y by Molmil](/molmil-images/mine/1y4y) | X-ray crystal structure of Bacillus stearothermophilus Histidine phosphocarrier protein (Hpr) | Descriptor: | Phosphocarrier protein HPr, SULFATE ION | Authors: | Sridharan, S, Razvi, A, Scholtz, J.M, Sacchettini, J.C. | Deposit date: | 2004-12-01 | Release date: | 2005-02-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The HPr proteins from the thermophile Bacillus stearothermophilus can form domain-swapped dimers. J.Mol.Biol., 346, 2005
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1Y50
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![BU of 1y50 by Molmil](/molmil-images/mine/1y50) | X-ray crystal structure of Bacillus stearothermophilus Histidine phosphocarrier protein (Hpr) F29W mutant domain_swapped dimer | Descriptor: | Phosphocarrier protein HPr, SULFATE ION | Authors: | Sridharan, S, Razvi, A, Scholtz, J.M, Sacchettini, J.C. | Deposit date: | 2004-12-01 | Release date: | 2005-02-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The HPr proteins from the thermophile Bacillus stearothermophilus can form domain-swapped dimers. J.Mol.Biol., 346, 2005
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1Y51
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![BU of 1y51 by Molmil](/molmil-images/mine/1y51) | X-ray crystal structure of Bacillus stearothermophilus Histidine phosphocarrier protein (Hpr) F29W mutant | Descriptor: | Phosphocarrier protein HPr, SULFATE ION | Authors: | Sridharan, S, Razvi, A, Scholtz, J.M, Sacchettini, J.C. | Deposit date: | 2004-12-01 | Release date: | 2005-02-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | The HPr proteins from the thermophile Bacillus stearothermophilus can form domain-swapped dimers. J.Mol.Biol., 346, 2005
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4D92
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![BU of 4d92 by Molmil](/molmil-images/mine/4d92) | Salmonella typhimurium D-Cysteine desulfhydrase soaked with beta-chloro-D-alanine shows pyruvate bound 4 A away from active site | Descriptor: | BENZAMIDINE, D-cysteine desulfhydrase, PYRUVIC ACID, ... | Authors: | Bharath, S.R, Shveta, B, Rajesh, K.H, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2012-01-11 | Release date: | 2012-05-30 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Structural and Mutational Studies on Substrate Specificity and Catalysis of Salmonella typhimurium D-Cysteine Desulfhydrase. Plos One, 7, 2012
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4D96
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![BU of 4d96 by Molmil](/molmil-images/mine/4d96) | D-Cysteine desulfhydrase from Salmonella typhimurium complexed with 1-amino-1-carboxycyclopropane (ACC) | Descriptor: | BENZAMIDINE, D-cysteine desulfhydrase, N-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-Y-LMETHYL]-1-AMINO-CYCLOPROPANECARBOXYLIC ACID, ... | Authors: | Bharath, S.R, Shveta, B, Rajesh, K.H, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2012-01-11 | Release date: | 2012-05-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Structural and Mutational Studies on Substrate Specificity and Catalysis of Salmonella typhimurium D-Cysteine Desulfhydrase. Plos One, 7, 2012
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5C2T
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![BU of 5c2t by Molmil](/molmil-images/mine/5c2t) | Crystal structure of Mitochondrial rhodoquinol-fumarate reductase from Ascaris suum with rhodoquinone-2 | Descriptor: | 2-amino-5-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-3-methoxy-6-methylcyclohexa-2,5-diene-1,4-dione, Cytochrome b-large subunit, FE2/S2 (INORGANIC) CLUSTER, ... | Authors: | Harada, S, Shiba, T, Sato, D, Yamamoto, A, Nagahama, M, Yone, A, Inaoka, D.K, Sakamoto, K, Inoue, M, Honma, T, Kita, K. | Deposit date: | 2015-06-16 | Release date: | 2015-08-05 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria Int J Mol Sci, 16, 2015
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4D9B
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![BU of 4d9b by Molmil](/molmil-images/mine/4d9b) | Pyridoxamine 5' phosphate (PMP) bound form of Salmonella typhimurium D-Cysteine desulfhydrase obtained after co-crystallization with D-cycloserine | Descriptor: | 1,2-ETHANEDIOL, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, BENZAMIDINE, ... | Authors: | Bharath, S.R, Shveta, B, Rajesh, K.H, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2012-01-11 | Release date: | 2012-05-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.67 Å) | Cite: | Structural and Mutational Studies on Substrate Specificity and Catalysis of Salmonella typhimurium D-Cysteine Desulfhydrase. Plos One, 7, 2012
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4D8T
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![BU of 4d8t by Molmil](/molmil-images/mine/4d8t) | Crystal structure of D-Cysteine desulfhydrase from Salmonella typhimurium at 2.2 A resolution | Descriptor: | BENZAMIDINE, CHLORIDE ION, D-cysteine desulfhydrase, ... | Authors: | Bharath, S.R, Shveta, B, Rajesh, K.H, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2012-01-11 | Release date: | 2012-05-30 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | Structural and Mutational Studies on Substrate Specificity and Catalysis of Salmonella typhimurium D-Cysteine Desulfhydrase. Plos One, 7, 2012
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4D8U
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![BU of 4d8u by Molmil](/molmil-images/mine/4d8u) | Crystal structure of D-Cysteine desulfhydrase from Salmonella typhimurium at 3.3 A in monoclinic space group with 8 subunits in the asymmetric unit | Descriptor: | D-cysteine desulfhydrase, PHOSPHATE ION | Authors: | Bharath, S.R, Shveta, B, Rajesh, K.H, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2012-01-11 | Release date: | 2012-05-30 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structural and Mutational Studies on Substrate Specificity and Catalysis of Salmonella typhimurium D-Cysteine Desulfhydrase. Plos One, 7, 2012
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4D8W
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![BU of 4d8w by Molmil](/molmil-images/mine/4d8w) | Salmonella typhimurium D-Cysteine desulfhydrase soaked with D-cys shows pyruvate bound 4 A away from active site | Descriptor: | 1,2-ETHANEDIOL, BENZAMIDINE, CHLORIDE ION, ... | Authors: | Bharath, S.R, Shveta, B, Rajesh, K.H, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2012-01-11 | Release date: | 2012-05-30 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Structural and Mutational Studies on Substrate Specificity and Catalysis of Salmonella typhimurium D-Cysteine Desulfhydrase. Plos One, 7, 2012
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5H3S
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![BU of 5h3s by Molmil](/molmil-images/mine/5h3s) | apo form of GEMIN5-WD | Descriptor: | GLYCEROL, Gem-associated protein 5 | Authors: | Bharath, S.R, Tang, X, Song, H. | Deposit date: | 2016-10-27 | Release date: | 2016-12-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural basis for specific recognition of pre-snRNA by Gemin5 Cell Res., 26, 2016
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5H3T
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![BU of 5h3t by Molmil](/molmil-images/mine/5h3t) | m7G cap bound to GEMIN5-WD | Descriptor: | 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, GLYCEROL, Gem-associated protein 5 | Authors: | Bharath, S.R, Tang, X, Song, H. | Deposit date: | 2016-10-27 | Release date: | 2016-12-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.571 Å) | Cite: | Structural basis for specific recognition of pre-snRNA by Gemin5 Cell Res., 26, 2016
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5H3U
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![BU of 5h3u by Molmil](/molmil-images/mine/5h3u) | Sm RNA bound to GEMIN5-WD | Descriptor: | GLYCEROL, Gem-associated protein 5, RNA (5'-R(*AP*AP*UP*UP*UP*UP*UP*GP*AP*C)-3') | Authors: | Bharath, S.R, Tang, X, Song, H. | Deposit date: | 2016-10-27 | Release date: | 2016-12-28 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.499 Å) | Cite: | Structural basis for specific recognition of pre-snRNA by Gemin5 Cell Res., 26, 2016
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3H2Q
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![BU of 3h2q by Molmil](/molmil-images/mine/3h2q) | Human SOD1 H80R variant, P21 crystal form | Descriptor: | SULFATE ION, Superoxide dismutase [Cu-Zn], ZINC ION | Authors: | Seetharaman, S.V, Winkler, D.D, Taylor, A.B, Cao, X, Whitson, L.J, Doucette, P.A, Valentine, J.S, Carroll, M.C, Culotta, V.C, Hart, P.J. | Deposit date: | 2009-04-14 | Release date: | 2010-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structures of Pathogenic SOD1 Mutants H80R and D124V: Disrupted Zinc-binding
and Compromised Post-translational Modification by the Copper Chaperone CCS To be Published
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3H2P
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![BU of 3h2p by Molmil](/molmil-images/mine/3h2p) | Human SOD1 D124V Variant | Descriptor: | ACETYL GROUP, MALONATE ION, Superoxide dismutase [Cu-Zn], ... | Authors: | Seetharaman, S.V, Winkler, D.D, Taylor, A.B, Cao, X, Whitson, L.J, Doucette, P.A, Valentine, J.S, Carroll, M.C, Culotta, V.C, Hart, P.J. | Deposit date: | 2009-04-14 | Release date: | 2010-05-05 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Structures of Pathogenic SOD1 Mutants H80R and D124V: Disrupted Zinc-binding
and Compromised Post-translational Modification by the Copper Chaperone CCS To be Published
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3GTV
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![BU of 3gtv by Molmil](/molmil-images/mine/3gtv) | Human-mouse SOD1 chimera | Descriptor: | Superoxide dismutase [Cu-Zn], ZINC ION | Authors: | Seetharaman, S.V, Taylor, A.B, Hart, P.J. | Deposit date: | 2009-03-28 | Release date: | 2010-09-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structures of mouse SOD1 and human/mouse SOD1 chimeras. Arch.Biochem.Biophys., 503, 2010
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4D99
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![BU of 4d99 by Molmil](/molmil-images/mine/4d99) | Salmonella typhimurium D-Cysteine desulfhydrase with L-ser bound non-covalently at the active site | Descriptor: | BENZAMIDINE, D-cysteine desulfhydrase, SERINE, ... | Authors: | Bharath, S.R, Shveta, B, Rajesh, K.H, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2012-01-11 | Release date: | 2012-05-30 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Structural and Mutational Studies on Substrate Specificity and Catalysis of Salmonella typhimurium D-Cysteine Desulfhydrase. Plos One, 7, 2012
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4D9E
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![BU of 4d9e by Molmil](/molmil-images/mine/4d9e) | D-Cysteine desulfhydrase from Salmonella typhimurium complexed with L-cycloserine (LCS) | Descriptor: | BENZAMIDINE, D-Cysteine desulfhydrase, [5-hydroxy-6-methyl-4-({[(4E)-3-oxo-1,2-oxazolidin-4-ylidene]amino}methyl)pyridin-3-yl]methyl dihydrogen phosphate | Authors: | Bharath, S.R, Shveta, B, Rajesh, K.H, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2012-01-11 | Release date: | 2012-05-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.47 Å) | Cite: | Structural and Mutational Studies on Substrate Specificity and Catalysis of Salmonella typhimurium D-Cysteine Desulfhydrase. Plos One, 7, 2012
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4D9C
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![BU of 4d9c by Molmil](/molmil-images/mine/4d9c) | PMP bound form of Salmonella typhimurium D-Cysteine desulfhydrase obtained after co-crystallization with L-cycloserine | Descriptor: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, BENZAMIDINE, D-Cysteine desulfhydrase | Authors: | Bharath, S.R, Shveta, B, Rajesh, K.H, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2012-01-11 | Release date: | 2012-05-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Structural and Mutational Studies on Substrate Specificity and Catalysis of Salmonella typhimurium D-Cysteine Desulfhydrase. Plos One, 7, 2012
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4D9F
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![BU of 4d9f by Molmil](/molmil-images/mine/4d9f) | D-Cysteine desulfhydrase from Salmonella typhimurium complexed with D-cycloserine (DCS) | Descriptor: | BENZAMIDINE, D-Cysteine desulfhydrase, D-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-N,O-CYCLOSERYLAMIDE | Authors: | Bharath, S.R, Shveta, B, Rajesh, K.H, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2012-01-11 | Release date: | 2012-05-30 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Structural and Mutational Studies on Substrate Specificity and Catalysis of Salmonella typhimurium D-Cysteine Desulfhydrase. Plos One, 7, 2012
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4D97
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![BU of 4d97 by Molmil](/molmil-images/mine/4d97) | Salmonella typhimurium D-Cysteine desulfhydrase with D-ser bound at active site | Descriptor: | BENZAMIDINE, D-SERINE, D-cysteine desulfhydrase | Authors: | Bharath, S.R, Shveta, B, Rajesh, K.H, Savithri, H.S, Murthy, M.R.N. | Deposit date: | 2012-01-11 | Release date: | 2012-05-30 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Structural and Mutational Studies on Substrate Specificity and Catalysis of Salmonella typhimurium D-Cysteine Desulfhydrase. Plos One, 7, 2012
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5C3J
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![BU of 5c3j by Molmil](/molmil-images/mine/5c3j) | Crystal structure of Mitochondrial rhodoquinol-fumarate reductase from Ascaris suum with Ubiquinone-1 | Descriptor: | Cytochrome b-large subunit, FE2/S2 (INORGANIC) CLUSTER, FE3-S4 CLUSTER, ... | Authors: | Harada, S, Shiba, T, Sato, D, Yamamoto, A, Nagahama, M, Yone, A, Inaoka, D.K, Sakamoto, K, Inoue, M, Honma, T, Kita, K. | Deposit date: | 2015-06-17 | Release date: | 2016-06-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria To Be Published
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3GTT
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![BU of 3gtt by Molmil](/molmil-images/mine/3gtt) | Mouse SOD1 | Descriptor: | Superoxide dismutase [Cu-Zn], ZINC ION | Authors: | Seetharaman, S.V, Taylor, A.B, Hart, P.J. | Deposit date: | 2009-03-28 | Release date: | 2010-09-08 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structures of mouse SOD1 and human/mouse SOD1 chimeras. Arch.Biochem.Biophys., 503, 2010
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6L3R
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![BU of 6l3r by Molmil](/molmil-images/mine/6l3r) | Crystal structure of Ribonucleotide reductase R1 subunit, RRM1 in complex with 4-bromo-N-((1S,2R)-2-(naphthalen-1-yl)-1-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)propyl)benzenesulfonamide | Descriptor: | 4-bromo-N-((1S,2R)-2-(naphthalen-1-yl)-1-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)propyl)benzenesulfonamide, ACETATE ION, MAGNESIUM ION, ... | Authors: | Miyahara, S, Chong, K.T, Suzuki, T. | Deposit date: | 2019-10-15 | Release date: | 2020-10-28 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | TAS1553, a novel small molecule ribonucleotide reductase (RNR) subunit interaction inhibitor, displays remarkable anti-tumor activity To be published
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6L7L
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![BU of 6l7l by Molmil](/molmil-images/mine/6l7l) | Crystal structure of Ribonucleotide reductase R1 subunit, RRM1 in complex with 5-chloro-2-(N-((1S,2R)-2-(2,3-dihydro-1H-inden-4-yl)-1-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)propyl)sulfamoyl)benzamide | Descriptor: | 5-chloro-2-(N-((1S,2R)-2-(2,3-dihydro-1H-inden-4-yl)-1-(5-oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)propyl)sulfamoyl)benzamide, ACETATE ION, MAGNESIUM ION, ... | Authors: | Miyahara, S, Chong, K.T, Suzuki, T. | Deposit date: | 2019-11-01 | Release date: | 2020-11-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.171 Å) | Cite: | TAS1553, a novel small molecule ribonucleotide reductase (RNR) subunit interaction inhibitor, displays remarkable anti-tumor activity To be published
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