5AQG
 
 | | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | | 分子名称: | (2R,3R,4S,5R)-2-(3-AMINO-5-METHYL-1,4,5,6,8-PENTAAZAACENAPHTHYLEN-1(5H)-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BAG FAMILY MOLECULAR CHAPERONE REGULATOR 1, ... | | 著者 | Jones, A.M, Westwood, I.M, Osborne, J.D, Matthews, T.P, Cheeseman, M.D, Rowlands, M.G, Jeganathan, F, Burke, R, Lee, D, Kadi, N, Liu, M, Richards, M, McAndrew, C, Yahya, N, Dobson, S.E, Jones, K, Workman, P, Collins, I, van Montfort, R.L.M. | | 登録日 | 2015-09-22 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | | 主引用文献 | A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
Sci Rep, 6, 2016
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5ZZO
 | | Crystal structure of CcpE regulatory domain in complex with citrate from Staphyloccocus aureus | | 分子名称: | CITRATE ANION, LysR family transcriptional regulator | | 著者 | Chen, J, Wang, L, Shang, F, Xu, Y. | | 登録日 | 2018-06-04 | | 公開日 | 2018-06-20 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural and Biochemical Analysis of the Citrate-Responsive Mechanism of the Regulatory Domain of Catabolite Control Protein E from Staphylococcus aureus
Biochemistry, 57, 2018
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6KZW
 | | Crystal structure of YggS family pyridoxal phosphate-dependent enzyme PipY from Fusobacterium nucleatum | | 分子名称: | PHOSPHATE ION, Pyridoxal phosphate homeostasis protein | | 著者 | Chen, Y, Wang, L, Shang, F, Lan, J, Liu, W, Xu, Y. | | 登録日 | 2019-09-25 | | 公開日 | 2019-10-16 | | 最終更新日 | 2021-01-13 | | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | | 主引用文献 | Crystal structure of YggS family pyridoxal phosphate-dependent enzyme PipY from Fusobacterium nucleatum
To Be Published
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6E8W
 | | MPER-TM Domain of HIV-1 envelope glycoprotein (Env) | | 分子名称: | Envelope glycoprotein gp160 | | 著者 | Fu, Q, Shaik, M.M, Cai, Y, Ghantous, F, Piai, A, Peng, H, Rits-Volloch, S, Liu, Z, Harrison, S.C, Seaman, M.S, Chen, B, Chou, J.J. | | 登録日 | 2018-07-31 | | 公開日 | 2018-09-05 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of the membrane proximal external region of HIV-1 envelope glycoprotein.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6L3E
 | | Crystal structure of Salmonella enterica sugar-binding protein MalE | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ... | | 著者 | Wang, L, Chen, Y, Liu, W, Lan, J, Shang, F, Xu, Y. | | 登録日 | 2019-10-10 | | 公開日 | 2019-10-23 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The crystal structure of Salmonella enterica sugar-binding protein MalE
To Be Published
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6L0Z
 | | The crystal structure of Salmonella enterica sugar-binding protein MalE | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,5-anhydro-D-glucitol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... | | 著者 | Wang, L, Chen, Y, Liu, W, Lan, J, Shang, F, Xu, Y. | | 登録日 | 2019-09-27 | | 公開日 | 2019-10-16 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The crystal structure of Salmonella enterica sugar-binding protein MalE
To Be Published
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6L19
 | | The crystal structure of competence or damage-inducible protein from Enterobacter asburiae | | 分子名称: | CHLORIDE ION, GLYCEROL, PncC family amidohydrolase, ... | | 著者 | Wang, L, Chen, Y, Liu, W, Lan, J, Shang, F, Xu, Y. | | 登録日 | 2019-09-28 | | 公開日 | 2019-10-16 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | | 主引用文献 | The crystal structure of Competence or damage-inducible protein from Enterobacter asburiae
To Be Published
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6L1K
 | | Crystal structure of NADH-dependent butanol dehydrogenase A from Fusobacterium nucleatum | | 分子名称: | NADH-dependent butanol dehydrogenase A, PHOSPHATE ION | | 著者 | Lan, J, Shang, F, Liu, W, Xu, Y, Chen, Y. | | 登録日 | 2019-09-29 | | 公開日 | 2019-10-16 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Crystal structure of NADH-dependent butanol dehydrogenase A from Fusobacterium nucleatum
To Be Published
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5DEJ
 | | Transthyretin natural mutant A19D | | 分子名称: | CALCIUM ION, Transthyretin | | 著者 | Pereira, H.M, Ferreira, P, Andrade, C, Lima, C, Palhano, F, Foguel, D. | | 登録日 | 2015-08-25 | | 公開日 | 2016-08-31 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | | 主引用文献 | Crystal structure of human Transthyretin natural mutant A19D
To Be Published
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9CEU
 | | Spizellomyces punctatus Fanzor (SpuFz) State 1 | | 分子名称: | DNA (5'-D(P*CP*CP*TP*AP*TP*AP*GP*AP*TP*AP*TP*GP*CP*CP*CP*GP*GP*GP*TP*AP*CP*CP*G)-3'), DNA (5'-D(P*CP*GP*GP*TP*AP*CP*CP*CP*GP*GP*GP*CP*AP*TP*A)-3'), Maltose/maltodextrin-binding periplasmic protein, ... | | 著者 | Xu, P, Saito, M, Zhang, F. | | 登録日 | 2024-06-27 | | 公開日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | | 主引用文献 | Structural insights into the diversity and DNA cleavage mechanism of Fanzor.
Cell, 2024
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9CET
 | | Guillardia theta Fanzor (GtFz) State 3 | | 分子名称: | DNA (28-MER), DNA (5'-D(P*AP*TP*GP*AP*CP*TP*TP*CP*TP*CP*TP*TP*AP*AP*AP*GP*GP*CP*CP*CP*CP*GP*GP*G)-3'), Maltose/maltodextrin-binding periplasmic protein, ... | | 著者 | Xu, P, Saito, M, Zhang, F. | | 登録日 | 2024-06-27 | | 公開日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural insights into the diversity and DNA cleavage mechanism of Fanzor.
Cell, 2024
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9CF1
 | | Parasitella parasitica Fanzor (PpFz) State 2 | | 分子名称: | DNA (5'-D(P*AP*CP*CP*CP*GP*GP*GP*AP*TP*AP*A)-3'), DNA (5'-D(P*GP*CP*TP*GP*GP*AP*TP*GP*TP*TP*TP*AP*TP*CP*CP*CP*GP*GP*GP*T)-3'), DNA/RNA (51-MER), ... | | 著者 | Xu, P, Saito, M, Zhang, F. | | 登録日 | 2024-06-27 | | 公開日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | | 主引用文献 | Structural insights into the diversity and DNA cleavage mechanism of Fanzor.
Cell, 2024
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9CF0
 | | Parasitella parasitica Fanzor (PpFz) State 1 | | 分子名称: | DNA (5'-D(P*AP*CP*CP*CP*GP*GP*GP*AP*TP*AP*A)-3'), DNA (5'-D(P*TP*GP*TP*TP*TP*AP*TP*CP*CP*CP*GP*GP*GP*T)-3'), DNA/RNA (54-MER), ... | | 著者 | Xu, P, Saito, M, Zhang, F. | | 登録日 | 2024-06-27 | | 公開日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | Structural insights into the diversity and DNA cleavage mechanism of Fanzor.
Cell, 2024
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2MVZ
 | | Solution Structure for Cyclophilin A from Geobacillus Kaustophilus | | 分子名称: | Peptidyl-prolyl cis-trans isomerase | | 著者 | Holliday, M.J, Isern, N.G, Geoffrey, A.S, Zhang, F, Eisenmesser, E.Z. | | 登録日 | 2014-10-20 | | 公開日 | 2015-07-08 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure and Dynamics of GeoCyp: A Thermophilic Cyclophilin with a Novel Substrate Binding Mechanism That Functions Efficiently at Low Temperatures.
Biochemistry, 54, 2015
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8W1P
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9CER
 | | Guillardia theta Fanzor (GtFz) State 1 | | 分子名称: | Maltose/maltodextrin-binding periplasmic protein, Guillardia theta Fanzor1 chimera, RNA (142-MER) | | 著者 | Xu, P, Saito, M, Zhang, F. | | 登録日 | 2024-06-27 | | 公開日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | Structural insights into the diversity and DNA cleavage mechanism of Fanzor.
Cell, 2024
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9CES
 | | Guillardia theta Fanzor (GtFz) State 2 | | 分子名称: | DNA (5'-D(P*AP*TP*GP*AP*CP*TP*TP*CP*TP*CP*TP*TP*AP*AP*AP*GP*GP*CP*CP*CP*CP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*GP*GP*GP*GP*CP*CP*TP*TP*TP*AP*AP*G)-3'), Maltose/maltodextrin-binding periplasmic protein, ... | | 著者 | Xu, P, Saito, M, Zhang, F. | | 登録日 | 2024-06-27 | | 公開日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | | 主引用文献 | Structural insights into the diversity and DNA cleavage mechanism of Fanzor.
Cell, 2024
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9CEV
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9CEW
 | | Spizellomyces punctatus Fanzor (SpuFz) State 3 | | 分子名称: | DNA (29-MER), DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*CP*GP*GP*TP*AP*CP*CP*CP*GP*GP*GP*CP*AP*TP*A)-3'), ... | | 著者 | Xu, P, Saito, M, Zhang, F. | | 登録日 | 2024-06-27 | | 公開日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | | 主引用文献 | Structural insights into the diversity and DNA cleavage mechanism of Fanzor.
Cell, 2024
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9CEZ
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9CEY
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9CEX
 | | Spizellomyces punctatus Fanzor (SpuFz) State 4 | | 分子名称: | DNA (29-MER), DNA (5'-D(*(MG)*(MG)P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*CP*GP*GP*TP*AP*CP*CP*CP*GP*GP*GP*CP*AP*TP*A)-3'), ... | | 著者 | Xu, P, Saito, M, Zhang, F. | | 登録日 | 2024-06-27 | | 公開日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | | 主引用文献 | Structural insights into the diversity and DNA cleavage mechanism of Fanzor.
Cell, 2024
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9CF2
 | | Parasitella parasitica Fanzor (PpFz) State 3 | | 分子名称: | DNA (26-MER), DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), ... | | 著者 | Xu, P, Saito, M, Zhang, F. | | 登録日 | 2024-06-27 | | 公開日 | 2024-09-11 | | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | | 主引用文献 | Structural insights into the diversity and DNA cleavage mechanism of Fanzor.
Cell, 2024
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9CF3
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5AQV
 | | Fragment-based screening of HSP70 sheds light on the functional role of ATP-binding site residues | | 分子名称: | (1R,2S,3R,5R)-3-((5-(benzyloxy)quinazolin-4-yl)amino)-5-(hydroxymethyl)cyclopentane-1,2-diol, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, BAG FAMILY MOLECULAR CHAPERONE REGULATOR 1, ... | | 著者 | Jones, A.M, Westwood, I.M, Osborne, J.D, Matthews, T.P, Cheeseman, M.D, Rowlands, M.G, Jeganathan, F, Burke, R, Lee, D, Kadi, N, Liu, M, Richards, M, McAndrew, C, Yahya, N, Dobson, S.E, Jones, K, Workman, P, Collins, I, van Montfort, R.L.M. | | 登録日 | 2015-09-22 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
Sci Rep, 6, 2016
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