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PDB: 56 件

6UH1
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Structure of the EVA71 strain 11316 capsid
分子名称: SPHINGOSINE, VP1, VP2, ...
著者Lee, H, Hafenstein, S.
登録日2019-09-26
公開日2019-12-18
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Scaffold Simplification Strategy Leads to a Novel Generation of Dual Human Immunodeficiency Virus and Enterovirus-A71 Entry Inhibitors.
J.Med.Chem., 63, 2020
4GB3
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BU of 4gb3 by Molmil
Human coxsackievirus B3 strain RD coat protein
分子名称: MYRISTIC ACID, PALMITIC ACID, coat protein 1, ...
著者Yoder, J.D, Hafenstein, S.
登録日2012-07-26
公開日2012-09-26
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献The Crystal Structure of a Coxsackievirus B3-RD Variant and a Refined 9-Angstrom Cryo-Electron Microscopy Reconstruction of the Virus Complexed with Decay-Accelerating Factor (DAF) Provide a New Footprint of DAF on the Virus Surface.
J.Virol., 86, 2012
6DIZ
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EV-A71 strain 11316 complexed with tryptophan dendrimer MADAL_0385
分子名称: SPHINGOSINE, VP1, VP2, ...
著者Sun, L, Lee, H, Thibaut, H.J, Rivero-Buceta, E, Martinez-Gualda, B, Delang, L, Leyssen, P, Gago, F, San-Felix, A, Hafenstein, S, Mirabelli, C, Neyts, J.
登録日2018-05-24
公開日2019-04-24
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.59 Å)
主引用文献Viral engagement with host (co-)receptors blocked by a novel class of tryptophan dendrimers that targets the 5-fold-axis of the enterovirus-A71 capsid.
Plos Pathog., 15, 2019
2X5I
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BU of 2x5i by Molmil
Crystal structure echovirus 7
分子名称: LAURIC ACID, VP1, VP2, ...
著者Plevka, P, Hafenstein, S, Zhang, Y, Bowman, V.D, Chipman, P.R, Bator, C.M, Rossmann, M.G.
登録日2010-02-08
公開日2010-12-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Interaction of Decay-Accelerating Factor with Echovirus 7.
J.Virol., 84, 2010
6BT3
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BU of 6bt3 by Molmil
High-Resolution Structure Analysis of Antibody V5 Conformational Epitope on Human Papillomavirus 16
分子名称: Major capsid protein L1, V5 Fab Heavy-chain, V5 Fab Light-chain
著者Guan, J, Bywaters, S.M, Brendle, S.A, Ashley, R.E, Makhov, A.M, Conway, J.F, Christensen, N.D, Hafenstein, S.
登録日2017-12-05
公開日2018-01-17
最終更新日2018-01-24
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献High-Resolution Structure Analysis of Antibody V5 and U4 Conformational Epitopes on Human Papillomavirus 16.
Viruses, 9, 2017
6BSP
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High-Resolution Structure Analysis of Antibody V5 and U4 Conformational Epitope on Human Papillomavirus 16
分子名称: Major capsid protein L1, U4 Heavy chain, U4 Light chain
著者Guan, J, Bywaters, S.M, Brendle, S.A, Ashley, R.E, Makhov, A.M, Conway, J.F, Christenson, N.D, Hafenstein, S.
登録日2017-12-04
公開日2018-02-14
最終更新日2018-10-24
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献High-Resolution Structure Analysis of Antibody V5 and U4 Conformational Epitopes on Human Papillomavirus 16.
Viruses, 9, 2017
7KZF
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BU of 7kzf by Molmil
High resolution cryo EM analysis of HPV16 identifies minor structural protein L2 and describes capsid flexibility
分子名称: Major capsid protein L1
著者Hartmann, S.R, Goetschius, D.J, Hafenstein, S.
登録日2020-12-10
公開日2021-02-24
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献High resolution cryo EM analysis of HPV16 identifies minor structural protein L2 and describes capsid flexibility.
Sci Rep, 11, 2021
9C2T
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Infectious B19V capsid
分子名称: Alpha-1-antichymotrypsin His-Pro-less, Capsid protein 2
著者Lee, H, Hafenstein, S.
登録日2024-05-31
公開日2024-10-16
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Infectious parvovirus B19 circulates in the blood plasma coated with active host protease inhibitors
To be published
9C4F
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Infectious B19V capsid
分子名称: Capsid protein 2, Inter-alpha-trypsin inhibitor heavy chain H4
著者Lee, H, Hafenstein, S.
登録日2024-06-04
公開日2024-10-16
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Infectious parvovirus B19 circulates in the blood plasma coated with active host protease inhibitors
To Be Published
9C27
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Infectious B19V capsid
分子名称: Capsid protein 2
著者Lee, H, Hafenstein, S.
登録日2024-05-30
公開日2024-10-16
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Infectious parvovirus B19 circulates in the blood plasma coated with active host protease inhibitors
To Be Published
9D7K
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BU of 9d7k by Molmil
Infectious B19V capsid
分子名称: Alpha-1-antichymotrypsin
著者Lee, H, Hafenstein, S.
登録日2024-08-16
公開日2024-10-16
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Infectious parvovirus B19 circulates in the blood plasma coated with active host protease inhibitors
To Be Published
3JCX
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BU of 3jcx by Molmil
Canine Parvovirus complexed with Fab E
分子名称: Capsid protein 2, Fab E heavy chain, Fab E light chain
著者Organtini, L.J, Iketani, S, Huang, K, Ashley, R.E, Makhov, A.M, Conway, J.F, Parrish, C.R, Hafenstein, S.
登録日2016-03-21
公開日2016-07-20
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Near-Atomic Resolution Structure of a Highly Neutralizing Fab Bound to Canine Parvovirus.
J.Virol., 90, 2016
7JYI
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BU of 7jyi by Molmil
Subparticle Map of ZIKV MR-766
分子名称: E Glycoprotein, M protein
著者Jose, J, Hafenstein, S.
登録日2020-08-30
公開日2020-09-16
最終更新日2020-10-14
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Identification of a pocket factor that is critical to Zika virus assembly.
Nat Commun, 11, 2020
3J91
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BU of 3j91 by Molmil
Cryo-electron microscopy of Enterovirus 71 (EV71) procapsid in complex with Fab fragments of neutralizing antibody 22A12
分子名称: VP0, VP1, VP3
著者Shingler, K.L, Cifuente, J.O, Ashley, R.E, Makhov, A.M, Conway, J.F, Hafenstein, S.
登録日2014-11-24
公開日2014-12-10
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (8.8 Å)
主引用文献The enterovirus 71 procapsid binds neutralizing antibodies and rescues virus infection in vitro.
J.Virol., 89, 2015
3JD7
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The novel asymmetric entry intermediate of a picornavirus captured with nanodiscs
分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ...
著者Lee, H, Shingler, K.L, Organtini, L.J, Ashley, R.E, Makhov, A.M, Conway, J.F, Hafenstein, S.
登録日2016-04-29
公開日2016-09-14
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献The novel asymmetric entry intermediate of a picornavirus captured with nanodiscs.
Sci Adv, 2, 2016
3J8Z
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BU of 3j8z by Molmil
Cryo-EM reconstruction of quasi-HPV16 complex with H16.1A Fab
分子名称: H16.1A heavy chain, H16.1A light chain, L1
著者Guan, J, Hafenstein, S.
登録日2014-11-20
公開日2015-05-06
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (14 Å)
主引用文献Structural comparison of four different antibodies interacting with human papillomavirus 16 and mechanisms of neutralization.
Virology, 483, 2015
3J7G
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BU of 3j7g by Molmil
Electron cryo-microscopy of human papillomavirus 16 and H16.V5 Fab fragments
分子名称: L1
著者Lee, H, Hafenstein, S.
登録日2014-06-24
公開日2014-11-26
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (13.6 Å)
主引用文献A cryo-electron microscopy study identifies the complete H16.V5 epitope and reveals global conformational changes initiated by binding of the neutralizing antibody fragment.
J.Virol., 89, 2015
3JBA
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BU of 3jba by Molmil
The U4 antibody epitope on human papillomavirus 16 identified by cryo-EM
分子名称: H16.U4 antibody heavy chain, H16.U4 antibody light chain, Major capsid protein L1
著者Guan, J, Bywaters, S.M, Brendle, S.A, Lee, H, Ashley, R.E, Christensen, N.D, Hafenstein, S.
登録日2015-08-11
公開日2015-10-07
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (12 Å)
主引用文献The U4 Antibody Epitope on Human Papillomavirus 16 Identified by Cryo-electron Microscopy.
J.Virol., 89, 2015
3J6L
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BU of 3j6l by Molmil
Kinetic and Structural Analysis of Coxsackievirus B3 Receptor Interactions and Formation of the A-particle
分子名称: Coxsackievirus and adenovirus receptor, SULFATE ION
著者Organtini, L.J, Makhov, A.M, Conway, J.F, Hafenstein, S, Carson, S.D.
登録日2014-03-19
公開日2014-04-09
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Kinetic and structural analysis of coxsackievirus b3 receptor interactions and formation of the a-particle.
J.Virol., 88, 2014
3J6N
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BU of 3j6n by Molmil
Kinetic and Structural Analysis of Coxsackievirus B3 Receptor Interactions and Formation of the A-particle
分子名称: Coxsackie and adenovirus receptor
著者Organtini, L.J, Makhov, A.M, Conway, J.F, Hafenstein, S, Carson, S.D.
登録日2014-03-19
公開日2014-04-09
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Kinetic and structural analysis of coxsackievirus b3 receptor interactions and formation of the a-particle.
J.Virol., 88, 2014
3J93
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BU of 3j93 by Molmil
Fitting of Fab into the cryoEM density map of EV71 procapsid in complex with Fab22A12
分子名称: neutralizing antibody 22A12, heavy chain, light chain
著者Shingler, K.L, Cifuente, J.O, Ashley, R.E, Makhov, A.M, Conway, J.F, Hafenstein, S.
登録日2014-12-02
公開日2014-12-24
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (8.8 Å)
主引用文献The enterovirus 71 procapsid binds neutralizing antibodies and rescues virus infection in vitro.
J.Virol., 89, 2015
3J8W
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BU of 3j8w by Molmil
Cryo-EM reconstruction of quasi-HPV16 complex with H263.A2 Fab
分子名称: H263.A2 heavy chain, H263.A2 light chain, L1
著者Guan, J, Hafenstein, S.
登録日2014-11-19
公開日2015-05-06
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (13 Å)
主引用文献Structural comparison of four different antibodies interacting with human papillomavirus 16 and mechanisms of neutralization.
Virology, 483, 2015
3J8V
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BU of 3j8v by Molmil
Cryo-EM reconstruction of quasi-HPV16 complex with H16.14J Fab
分子名称: H16.14J heavy chain, H16.14J light chain, L1
著者Guan, J, Hafenstein, S.
登録日2014-11-19
公開日2015-05-06
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (13.9 Å)
主引用文献Structural comparison of four different antibodies interacting with human papillomavirus 16 and mechanisms of neutralization.
Virology, 483, 2015
3EPD
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BU of 3epd by Molmil
CryoEM structure of poliovirus receptor bound to poliovirus type 3
分子名称: MYRISTIC ACID, Poliovirus Type3 peptide, Poliovirus receptor, ...
著者Zhang, P, Mueller, S, Morais, M.C, Bator, C.M, Bowman, V.D, Hafenstein, S, Wimmer, E, Rossmann, M.G.
登録日2008-09-29
公開日2008-11-11
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Crystal structure of CD155 and electron microscopic studies of its complexes with polioviruses.
Proc.Natl.Acad.Sci.USA, 105, 2008
3EPF
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BU of 3epf by Molmil
CryoEM structure of poliovirus receptor bound to poliovirus type 2
分子名称: 1[2-CHLORO-4-METHOXY-PHENYL-OXYMETHYL]-4-[2,6-DICHLORO-PHENYL-OXYMETHYL]-BENZENE, MYRISTIC ACID, Poliovirus receptor, ...
著者Zhang, P, Mueller, S, Morais, M.C, Bator, C.M, Bowman, V.D, Hafenstein, S, Wimmer, E, Rossmann, M.G.
登録日2008-09-29
公開日2008-11-11
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Crystal structure of CD155 and electron microscopic studies of its complexes with polioviruses.
Proc.Natl.Acad.Sci.USA, 105, 2008

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