4MS6
| Human Leukotriene A4 Hydrolase in complex with Pro-Gly-Pro analogue | 分子名称: | 1-{4-oxo-4-[(2S)-pyrrolidin-2-yl]butanoyl}-L-proline, ACETIC ACID, Leukotriene A-4 hydrolase, ... | 著者 | Stsiapanava, A, Rinaldo-Matthis, A, Haeggstrom, J.Z. | 登録日 | 2013-09-18 | 公開日 | 2014-03-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Binding of Pro-Gly-Pro at the active site of leukotriene A4 hydrolase/aminopeptidase and development of an epoxide hydrolase selective inhibitor. Proc.Natl.Acad.Sci.USA, 111, 2014
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2XPY
| Structure of Native Leukotriene A4 Hydrolase from Saccharomyces cerevisiae | 分子名称: | GLUTATHIONE, GLYCEROL, LEUKOTRIENE A-4 HYDROLASE, ... | 著者 | Helgstrand, C, Hasan, M, Usyal, H, Haeggstrom, J.Z, Thunnissen, M.M.G.M. | 登録日 | 2010-08-31 | 公開日 | 2010-12-29 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | A Leukotriene A(4) Hydrolase-Related Aminopeptidase from Yeast Undergoes Induced Fit Upon Inhibitor Binding. J.Mol.Biol., 406, 2011
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4J7Y
| Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis | 分子名称: | D-gamma-glutamyl-(Z)-N-(carboxymethylidene)-S-[(2R)-2-hydroxy-4-phenylbutyl]-L-cysteinamide, Leukotriene C4 synthase, NICKEL (II) ION, ... | 著者 | Niegowski, D, Rinaldo-Matthis, A, Haeggstrom, J.Z. | 登録日 | 2013-02-14 | 公開日 | 2014-01-01 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.901 Å) | 主引用文献 | Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM. J.Biol.Chem., 289, 2014
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4L2L
| Human Leukotriene A4 Hydrolase complexed with ligand 4-(4-benzylphenyl)thiazol-2-amine | 分子名称: | 4-(4-benzylphenyl)-1,3-thiazol-2-amine, ACETATE ION, Leukotriene A-4 hydrolase, ... | 著者 | Stsiapanava, A, Rinaldo-Matthis, A, Haeggstrom, J.Z. | 登録日 | 2013-06-04 | 公開日 | 2014-03-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.648 Å) | 主引用文献 | Binding of Pro-Gly-Pro at the active site of leukotriene A4 hydrolase/aminopeptidase and development of an epoxide hydrolase selective inhibitor. Proc.Natl.Acad.Sci.USA, 111, 2014
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4JRZ
| Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis | 分子名称: | Leukotriene C4 synthase, NICKEL (II) ION, PALMITIC ACID, ... | 著者 | Niegowski, D, Rinaldo-Matthis, A, Haeggstrom, J.Z. | 登録日 | 2013-03-22 | 公開日 | 2014-01-01 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM. J.Biol.Chem., 289, 2014
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4JC7
| Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis | 分子名称: | Leukotriene C4 synthase, NICKEL (II) ION, PALMITIC ACID, ... | 著者 | Niegowski, D, Rinaldo-Matthis, A, Haeggstrom, J.Z. | 登録日 | 2013-02-21 | 公開日 | 2014-01-01 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM. J.Biol.Chem., 289, 2014
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4JCZ
| Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis | 分子名称: | Leukotriene C4 synthase, NICKEL (II) ION, PALMITIC ACID, ... | 著者 | Niegowski, D, Rinaldo-Matthis, A, Haeggstrom, J.Z. | 登録日 | 2013-02-22 | 公開日 | 2014-01-01 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM. J.Biol.Chem., 289, 2014
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4J7T
| Human LTC4 synthase in complex with product analogs - implications for enzyme catalysis | 分子名称: | D-gamma-glutamyl-S-(4-phenylbutyl)-L-cysteinylglycine, Leukotriene C4 synthase, NICKEL (II) ION, ... | 著者 | Niegowski, D, Rinaldo-Matthis, A, Haeggstrom, J.Z. | 登録日 | 2013-02-14 | 公開日 | 2014-01-01 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.203 Å) | 主引用文献 | Crystal Structures of Leukotriene C4 Synthase in Complex with Product Analogs: IMPLICATIONS FOR THE ENZYME MECHANISM. J.Biol.Chem., 289, 2014
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1SQM
| STRUCTURE OF [R563A] LEUKOTRIENE A4 HYDROLASE | 分子名称: | ACETIC ACID, IMIDAZOLE, LEUKOTRIENE A-4 HYDROLASE, ... | 著者 | Tholander, F.O.T, Rudberg, P.C, Thunnissen, M.M.G.M, Haeggstrom, J.Z. | 登録日 | 2004-03-19 | 公開日 | 2004-08-03 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Leukotriene A4 hydrolase: identification of a common carboxylate recognition site for the epoxide hydrolase and aminopeptidase substrates J.Biol.Chem., 279, 2004
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