6SS2
| Structure of arginase-2 in complex with the inhibitory human antigen-binding fragment Fab C0021158 | 分子名称: | Arginase-2, mitochondrial, Fab C0021158 heavy chain (IgG1), ... | 著者 | Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M. | 登録日 | 2019-09-06 | 公開日 | 2020-06-10 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action. Mabs, 12
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6SS0
| Structure of the arginase-2-inhibitory human antigen-binding fragment Fab C0021181 | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Fab C0021181 heavy chain (IgG1), ... | 著者 | Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M. | 登録日 | 2019-09-06 | 公開日 | 2020-06-10 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action. Mabs, 12
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6SS6
| Structure of arginase-2 in complex with the inhibitory human antigen-binding fragment Fab C0020187 | 分子名称: | Arginase-2, mitochondrial, Fab C0020187 heavy chain (IgG1), ... | 著者 | Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M. | 登録日 | 2019-09-06 | 公開日 | 2020-06-10 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Extensive sequence and structural evolution of Arginase 2 inhibitory antibodies enabled by an unbiased approach to affinity maturation. Proc.Natl.Acad.Sci.USA, 117, 2020
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6SRX
| Structure of the arginase-2-inhibitory human antigen-binding fragment Fab C0021158 | 分子名称: | ACETATE ION, CHLORIDE ION, Fab C0021158 heavy chain (IgG1), ... | 著者 | Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M. | 登録日 | 2019-09-06 | 公開日 | 2020-06-10 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action. Mabs, 12
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6SRV
| Structure of the arginase-2-inhibitory human antigen-binding fragment Fab C0021144 | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... | 著者 | Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M. | 登録日 | 2019-09-06 | 公開日 | 2020-06-10 | 最終更新日 | 2020-09-16 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action. Mabs, 12
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6TUL
| Structure of the arginase-2-inhibitory human antigen-binding fragment Fab C0021177 | 分子名称: | D-MALATE, Fab C0021177 heavy chain (IgG1), Fab C0021177 light chain (IgG1), ... | 著者 | Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M. | 登録日 | 2020-01-07 | 公開日 | 2020-06-10 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action. Mabs, 12
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6SS5
| Structure of the arginase-2-inhibitory human antigen-binding fragment Fab C0020187 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ... | 著者 | Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M. | 登録日 | 2019-09-06 | 公開日 | 2020-06-10 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | 主引用文献 | Extensive sequence and structural evolution of Arginase 2 inhibitory antibodies enabled by an unbiased approach to affinity maturation. Proc.Natl.Acad.Sci.USA, 117, 2020
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5MC7
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5ILN
| Crystal structure of Aspartate Transcarbamoylase from Plasmodium falciparum (PfATC) with bound citrate | 分子名称: | Aspartate carbamoyltransferase, CITRATE ANION, GLYCEROL, ... | 著者 | Lunev, S, Bosch, S.S, Batista, F.D.A, Wrenger, C, Groves, M.R. | 登録日 | 2016-03-04 | 公開日 | 2017-03-29 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Crystal structure of truncated Aspartate Transcarbamoylase from Plasmodium falciparum To be published
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2W9Y
| The structure of the lipid binding protein Ce-FAR-7 from Caenorhabditis elegans | 分子名称: | FATTY ACID/RETINOL BINDING PROTEIN PROTEIN 7, ISOFORM A, CONFIRMED BY TRANSCRIPT EVIDENCE, ... | 著者 | Jordanova, R, Groves, M.R, Tucker, P.A. | 登録日 | 2009-01-30 | 公開日 | 2009-10-20 | 最終更新日 | 2015-04-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Fatty Acid and Retinoid Binding Proteins Have Distinct Binding Pockets for the Two Types of Cargo J.Biol.Chem., 284, 2009
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5ILQ
| Crystal structure of truncated unliganded Aspartate Transcarbamoylase from Plasmodium falciparum | 分子名称: | Aspartate carbamoyltransferase, GLYCEROL, SULFATE ION | 著者 | Lunev, S, Bosch, S.S, Batista, F.D.A, Wrenger, C, Groves, M.R. | 登録日 | 2016-03-04 | 公開日 | 2016-06-08 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of truncated aspartate transcarbamoylase from Plasmodium falciparum. Acta Crystallogr.,Sect.F, 72, 2016
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6RRR
| Crystal structure of the tyrosinase PvdP from Pseudomonas aeruginosa | 分子名称: | GLYCEROL, PvdP | 著者 | Wibowo, J.P, Batista, F.A, van Oosterwijk, N, Groves, M.R, Dekker, F.J, Quax, W.J. | 登録日 | 2019-05-20 | 公開日 | 2020-04-15 | 実験手法 | X-RAY DIFFRACTION (2.11 Å) | 主引用文献 | A novel mechanism of inhibition by phenylthiourea on PvdP, a tyrosinase synthesizing pyoverdine of Pseudomonas aeruginosa. Int.J.Biol.Macromol., 146, 2020
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6RRQ
| Crystal structure of tyrosinase PvdP from Pseudomonas aeruginosa bound to copper | 分子名称: | COPPER (II) ION, GLYCEROL, PvdP | 著者 | Wibowo, J.P, Batista, F.A, van Oosterwijk, N, Groves, M.R, Dekker, F.J, Quax, W.J. | 登録日 | 2019-05-20 | 公開日 | 2020-04-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | A novel mechanism of inhibition by phenylthiourea on PvdP, a tyrosinase synthesizing pyoverdine of Pseudomonas aeruginosa. Int.J.Biol.Macromol., 146, 2020
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6RRP
| Crystal structure of tyrosinase PvdP from Pseudomonas aeruginosa bound to copper and phenylthiourea | 分子名称: | COPPER (II) ION, N-PHENYLTHIOUREA, PvdP | 著者 | Wibowo, J.P, Batista, F.A, van Oosterwijk, N, Groves, M.R, Dekker, F.J, Quax, W.J. | 登録日 | 2019-05-20 | 公開日 | 2020-04-15 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A novel mechanism of inhibition by phenylthiourea on PvdP, a tyrosinase synthesizing pyoverdine of Pseudomonas aeruginosa. Int.J.Biol.Macromol., 146, 2020
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5OJE
| Endothiapepsin with Ligand VSK-B24 | 分子名称: | (2~{S})-2-azanyl-3-(1~{H}-indol-3-yl)-~{N}-[2-(2,4,6-trimethylphenyl)ethyl]propanamide, DIMETHYL SULFOXIDE, Endothiapepsin, ... | 著者 | Gierse, R.M, Magari, F, Groves, M.R, Heine, A, Klebe, G, Hirsch, A. | 登録日 | 2017-07-21 | 公開日 | 2018-09-12 | 最終更新日 | 2018-11-21 | 実験手法 | X-RAY DIFFRACTION (1.579 Å) | 主引用文献 | Design and Synthesis of Bioisosteres of Acylhydrazones as Stable Inhibitors of the Aspartic Protease Endothiapepsin. ChemMedChem, 13, 2018
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3LCY
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6HT5
| Oct4/Sox2:UTF1 structure | 分子名称: | DNA (5'-D(*TP*TP*CP*AP*CP*TP*AP*GP*CP*AP*TP*AP*AP*CP*AP*AP*TP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*CP*AP*TP*TP*GP*TP*TP*AP*TP*GP*CP*TP*AP*GP*TP*GP*AP*AP*G)-3'), POU domain, ... | 著者 | Vahokoski, J, Meusch, D, Groves, M, Pogenberg, V, Wilmanns, M. | 登録日 | 2018-10-03 | 公開日 | 2019-10-23 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.451 Å) | 主引用文献 | Oct4/Sox2:UTF1 structure To Be Published
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