4GK7
 
 | | yeast 20S proteasome in complex with the Syringolin-Glidobactin chimera | | 分子名称: | Proteasome component C1, Proteasome component C11, Proteasome component C5, ... | | 著者 | Groll, M, Stein, M.L, Bachmann, A. | | 登録日 | 2012-08-10 | | 公開日 | 2012-08-29 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Activity enhancement of the synthetic syrbactin proteasome inhibitor hybrid and biological evaluation in tumor cells.
Biochemistry, 51, 2012
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1RYP
 | | CRYSTAL STRUCTURE OF THE 20S PROTEASOME FROM YEAST AT 2.4 ANGSTROMS RESOLUTION | | 分子名称: | 20S PROTEASOME, MAGNESIUM ION | | 著者 | Groll, M, Ditzel, L, Loewe, J, Stock, D, Bochtler, M, Bartunik, H.D, Huber, R. | | 登録日 | 1997-02-26 | | 公開日 | 1998-04-15 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of 20S proteasome from yeast at 2.4 A resolution.
Nature, 386, 1997
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1G0U
 | | A GATED CHANNEL INTO THE PROTEASOME CORE PARTICLE | | 分子名称: | MAGNESIUM ION, PROTEASOME COMPONENT C1, PROTEASOME COMPONENT C11, ... | | 著者 | Groll, M, Bajorek, M, Kohler, A, Moroder, L, Rubin, D.M, Huber, R, Glickman, M.H, Finley, D. | | 登録日 | 2000-10-09 | | 公開日 | 2000-11-06 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | A gated channel into the proteasome core particle.
Nat.Struct.Biol., 7, 2000
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1G65
 | | Crystal structure of epoxomicin:20s proteasome reveals a molecular basis for selectivity of alpha,beta-epoxyketone proteasome inhibitors | | 分子名称: | EPOXOMICIN (peptide inhibitor), MAGNESIUM ION, Proteasome component C1, ... | | 著者 | Groll, M, Kim, K.B, Kairies, N, Huber, R, Crews, C. | | 登録日 | 2000-11-03 | | 公開日 | 2000-11-27 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Crystal Structure of Epoxomicin:20S Proteasome reveals a molecular basis for selectivity of alpha,beta-Epoxyketone Proteasome Inhibitors
J.Am.Chem.Soc., 122, 2000
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2GPL
 | | TMC-95 based biphenyl-ether macrocycles: specific proteasome inhibitors | | 分子名称: | BENZYL [12-(2-AMINO-2-OXOETHYL)-4-NITRO-10,13-DIOXO-15-[(PROPYLAMINO)CARBONYL]-2-OXA-11,14-DIAZATRICYCLO[15 .2.2.1~3,7~]DOCOSA-1(19),3(22),4,6,17,20-HEXAEN-9-YL]CARBAMATE, Proteasome component C1, Proteasome component C11, ... | | 著者 | Groll, M, Goetz, M, Kaiser, M, Weyher, E, Moroder, M. | | 登録日 | 2006-04-18 | | 公開日 | 2006-07-11 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | TMC-95-Based Inhibitor Design Provides Evidence for the Catalytic Versatility of the Proteasome.
Chem.Biol., 13, 2006
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2R2Y
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7NCB
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7NC9
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7NCM
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7NCU
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7NCT
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7NC2
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7NCE
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7NCL
 | | Glutathione-S-transferase GliG mutant E82Q | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Glutathione S-transferase GliG | | 著者 | Groll, M, Huber, E.M. | | 登録日 | 2021-01-29 | | 公開日 | 2021-05-12 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and Mechanistic Insights into C-S Bond Formation in Gliotoxin.
Angew.Chem.Int.Ed.Engl., 60, 2021
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7NC1
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7NCD
 | | Glutathione-S-transferase GliG mutant N27D | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Glutathione S-transferase GliG, ... | | 著者 | Groll, M, Huber, E.M. | | 登録日 | 2021-01-28 | | 公開日 | 2021-05-12 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural and Mechanistic Insights into C-S Bond Formation in Gliotoxin.
Angew.Chem.Int.Ed.Engl., 60, 2021
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7NC8
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7NC6
 | | Glutathione-S-transferase GliG in complex with cyclo[L-Phe-L-Ser]-bis-glutathione-adduct | | 分子名称: | (2~{S})-2-azanyl-5-[[(2~{R})-3-[(2~{R},5~{R})-5-(hydroxymethyl)-3,6-bis(oxidanylidene)-2-(phenylmethyl)-5-sulfanyl-piperazin-2-yl]sulfanyl-1-(2-hydroxy-2-oxoethylamino)-1-oxidanylidene-propan-2-yl]amino]-5-oxidanylidene-pentanoic acid, 1,2-ETHANEDIOL, ACETATE ION, ... | | 著者 | Groll, M, Huber, E.M. | | 登録日 | 2021-01-28 | | 公開日 | 2021-05-12 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural and Mechanistic Insights into C-S Bond Formation in Gliotoxin.
Angew.Chem.Int.Ed.Engl., 60, 2021
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7NCO
 | | Glutathione-S-transferase GliG mutant K127R | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Glutathione S-transferase GliG | | 著者 | Groll, M, Huber, E.M. | | 登録日 | 2021-01-29 | | 公開日 | 2021-05-12 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural and Mechanistic Insights into C-S Bond Formation in Gliotoxin.
Angew.Chem.Int.Ed.Engl., 60, 2021
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7NC5
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7NCN
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7NC3
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7NCP
 | | Glutathione-S-transferase GliG mutant K127A | | 分子名称: | 1,2-ETHANEDIOL, Glutathione S-transferase GliG, SODIUM ION | | 著者 | Groll, M, Huber, E.M. | | 登録日 | 2021-01-29 | | 公開日 | 2021-05-12 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structural and Mechanistic Insights into C-S Bond Formation in Gliotoxin.
Angew.Chem.Int.Ed.Engl., 60, 2021
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2ZCY
 | | yeast 20S proteasome:syringolin A-complex | | 分子名称: | (2S)-2-[[(2S)-1-[[(5S,8S,9E)-2,7-dioxo-5-propan-2-yl-1,6-diazacyclododeca-3,9-dien-8-yl]amino]-3-methyl-1-oxo-butan-2-yl]carbamoylamino]-3-methyl-butanoic acid, Proteasome component C1, Proteasome component C11, ... | | 著者 | Groll, M, Dudler, R, Kaiser, M. | | 登録日 | 2007-11-15 | | 公開日 | 2008-04-08 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism
Nature, 452, 2008
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3BDM
 | | yeast 20S proteasome:glidobactin A-complex | | 分子名称: | (2E,4E)-N-[(2S,3R)-3-hydroxy-1-[[(3Z,5S,8S,10S)-10-hydroxy-5-methyl-2,7-dioxo-1,6-diazacyclododec-3-en-8-yl]amino]-1-ox obutan-2-yl]dodeca-2,4-dienamide, Proteasome component C1, Proteasome component C11, ... | | 著者 | Groll, M, Dudler, R, Kaiser, M. | | 登録日 | 2007-11-15 | | 公開日 | 2008-04-08 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | A plant pathogen virulence factor inhibits the eukaryotic proteasome by a novel mechanism
Nature, 452, 2008
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