3V72
| Crystal Structure of Rat DNA polymerase beta Mutator E295K: Enzyme-dsDNA | Descriptor: | CHLORIDE ION, DNA 5'-D(P*AP*AP*AP*CP*TP*CP*AP*CP*AP*T)-3', DNA 5'-D(P*AP*TP*GP*TP*GP*AP*GP*T)-3', ... | Authors: | Gridley, C.L, Jaeger, J. | Deposit date: | 2011-12-20 | Release date: | 2012-07-04 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Unfavorable Electrostatic and Steric Interactions in DNA Polymerase beta E295K Mutant Interfere with the Enzyme s Pathway J.Am.Chem.Soc., 134, 2012
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3UXN
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3UXO
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3UXP
| Co-crystal Structure of Rat DNA polymerase beta Mutator I260Q: Enzyme-DNA-ddTTP | Descriptor: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA 5'-D(P*AP*CP*TP*CP*AP*CP*AP*TP*A)-3', DNA 5'-D(P*AP*TP*GP*TP*GP*AP*G)-3', ... | Authors: | Gridley, C.L, Jaeger, J. | Deposit date: | 2011-12-05 | Release date: | 2012-12-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.723 Å) | Cite: | Structural Changes in the Hydrophobic Hinge Region Adversely Affect the Activity and Fidelity of the I260Q Mutator DNA Polymerase beta. Biochemistry, 52, 2013
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