8UW1
 
 | | Cryo-EM structure of DNMT3A1 UDR in complex with H2AK119Ub-nucleosome | | Descriptor: | DNA (146-MER), DNA (cytosine-5)-methyltransferase 3A, Histone H2A, ... | | Authors: | Gretarsson, K, Abini-Agbomson, S, Armache, K.-J, Lu, C. | | Deposit date: | 2023-11-05 | | Release date: | 2024-09-11 | | Method: | ELECTRON MICROSCOPY (2.88 Å) | | Cite: | Cancer-associated DNA hypermethylation of Polycomb targets requires DNMT3A dual recognition of histone H2AK119 ubiquitination and the nucleosome acidic patch.
Sci Adv, 10, 2024
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