5M61
 
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5M5V
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5M5U
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5M5T
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5M5S
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2YGB
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2YGC
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2X45
 | | Crystal Structure of Arg r 1 in complex with histamine | | Descriptor: | ALLERGEN ARG R 1, HISTAMINE | | Authors: | Paesen, G.C, Siebold, C, Syme, N, Harlos, K, Graham, S.C, Hilger, C, Homans, S.W, Hentges, F, Stuart, D.I. | | Deposit date: | 2010-01-28 | | Release date: | 2011-02-09 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Crystal Structure of the Allergen Arg R 1, a Histamine-Binding Lipocalin from a Soft Tick
To be Published
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4BBD
 | | THE STRUCTURE OF VACCINIA VIRUS N1 R58Y MUTANT | | Descriptor: | N1L | | Authors: | Maluquer de Motes, C, Cooray, S, McGourty, K, Ren, H, Bahar, M.W, Stuart, D.I, Grimes, J.M, Graham, S.C, Smith, G.L. | | Deposit date: | 2012-09-21 | | Release date: | 2012-10-03 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Inhibition of Apoptosis and NF-kappaB Activation by Vaccinia Protein N1 Occur Via Distinct Binding Surfaces and Make Different Contributions to Virulence.
Plos Pathog., 7, 2011
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4BBC
 | | THE STRUCTURE OF VACCINIA VIRUS N1 R71Y MUTANT | | Descriptor: | N1L | | Authors: | Maluquer de Motes, C, Cooray, S, McGourty, K, Ren, H, Bahar, M.W, Stuart, D.I, Grimes, J.M, Graham, S.C, Smith, G.L. | | Deposit date: | 2012-09-21 | | Release date: | 2012-10-03 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Inhibition of Apoptosis and NF-kappaB Activation by Vaccinia Protein N1 Occur Via Distinct Binding Surfaces and Make Different Contributions to Virulence.
Plos Pathog., 7, 2011
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4CCC
 | | STRUCTURE OF MOUSE GALACTOCEREBROSIDASE WITH 4NBDG: ENZYME-SUBSTRATE COMPLEX | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-nitrophenyl beta-D-galactopyranoside, ... | | Authors: | Hill, C.H, Graham, S.C, Read, R.J, Deane, J.E. | | Deposit date: | 2013-10-21 | | Release date: | 2013-12-11 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Structural Snapshots Illustrate the Catalytic Cycle of Beta-Galactocerebrosidase, the Defective Enzyme in Krabbe Disease
Proc.Natl.Acad.Sci.USA, 110, 2013
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4CCE
 | | STRUCTURE OF MOUSE GALACTOCEREBROSIDASE WITH GALACTOSE: ENZYME- PRODUCT COMPLEX | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | Authors: | Hill, C.H, Graham, S.C, Read, R.J, Deane, J.E. | | Deposit date: | 2013-10-21 | | Release date: | 2013-12-11 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | Structural Snapshots Illustrate the Catalytic Cycle of Beta-Galactocerebrosidase, the Defective Enzyme in Krabbe Disease
Proc.Natl.Acad.Sci.USA, 110, 2013
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4CCA
 | | Structure of human Munc18-2 | | Descriptor: | CHLORIDE ION, SYNTAXIN-BINDING PROTEIN 2 | | Authors: | Hackmann, Y, Graham, S.C, Ehl, S, Hoening, S, Lehmberg, K, Arico, M, Owen, D.J, Griffiths, G.G. | | Deposit date: | 2013-10-21 | | Release date: | 2013-10-30 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Syntaxin Binding Mechanism and Disease-Causing Mutations in Munc18-2
Proc.Natl.Acad.Sci.USA, 110, 2013
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4BBB
 | | THE STRUCTURE OF VACCINIA VIRUS N1 Q61Y MUTANT | | Descriptor: | N1L | | Authors: | Maluquer de Motes, C, Cooray, S, McGourty, K, Ren, H, Bahar, M.W, Stuart, D.I, Grimes, J.M, Graham, S.C, Smith, G.L. | | Deposit date: | 2012-09-21 | | Release date: | 2012-10-03 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (3.09 Å) | | Cite: | Inhibition of Apoptosis and NF-kappaB Activation by Vaccinia Protein N1 Occur Via Distinct Binding Surfaces and Make Different Contributions to Virulence.
Plos Pathog., 7, 2011
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4D5S
 | | Structure of A49 from Vaccinia Virus Western Reserve | | Descriptor: | A49R | | Authors: | Neidel, S, Maluquer de Motes, C, Mansur, D.S, Strnadova, P, Smith, G.L, Graham, S.C. | | Deposit date: | 2014-11-07 | | Release date: | 2015-01-21 | | Last modified: | 2024-10-23 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Vaccinia Virus Protein A49 is an Unexpected Member of the B-Cell Lymphoma (Bcl)-2 Protein Family
J.Biol.Chem., 290, 2015
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4D5T
 | | Structure of N-terminally truncated A49 from Vaccinia Virus Western Reserve | | Descriptor: | PROTEIN A49R, SULFATE ION | | Authors: | Neidel, S, Maluquer de Motes, C, Mansur, D.S, Strnadova, P, Smith, G.L, Graham, S.C. | | Deposit date: | 2014-11-07 | | Release date: | 2015-01-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.84 Å) | | Cite: | Vaccinia Virus Protein A49 is an Unexpected Member of the B-Cell Lymphoma (Bcl)-2 Protein Family
J.Biol.Chem., 290, 2015
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4CCD
 | | STRUCTURE OF MOUSE GALACTOCEREBROSIDASE WITH D-GALACTAL: ENZYME- INTERMEDIATE COMPLEX | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-deoxy-alpha-D-galactopyranose, ... | | Authors: | Hill, C.H, Graham, S.C, Read, R.J, Deane, J.E. | | Deposit date: | 2013-10-21 | | Release date: | 2013-12-11 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.97 Å) | | Cite: | Structural Snapshots Illustrate the Catalytic Cycle of Beta-Galactocerebrosidase, the Defective Enzyme in Krabbe Disease
Proc.Natl.Acad.Sci.USA, 110, 2013
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4D5R
 | | Structure of N-terminally truncated A49 from Vaccinia Virus Western Reserve | | Descriptor: | A49 | | Authors: | Neidel, S, Maluquer de Motes, C, Mansur, D.S, Strnadova, P, Smith, G.L, Graham, S.C. | | Deposit date: | 2014-11-07 | | Release date: | 2015-01-21 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Vaccinia Virus Protein A49 is an Unexpected Member of the B-Cell Lymphoma (Bcl)-2 Protein Family
J.Biol.Chem., 290, 2015
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2DFY
 | | Crystal structure of a cyclized protein fusion of LMO4 LIM domains 1 and 2 with the LIM interacting domain of LDB1 | | Descriptor: | GLYCEROL, ZINC ION, fusion protein of LIM domain transcription factor LMO4 and LIM domain-binding protein 1 | | Authors: | Jeffries, C.M.J, Graham, S.C, Collyer, C.A, Guss, J.M, Matthews, J.M. | | Deposit date: | 2006-03-06 | | Release date: | 2006-10-31 | | Last modified: | 2023-10-25 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Stabilization of a binary protein complex by intein-mediated cyclization
Protein Sci., 15, 2006
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2VT1
 | | Crystal structure of the cytoplasmic domain of Spa40, the specificity switch for the Shigella flexneri Type III Secretion System | | Descriptor: | SURFACE PRESENTATION OF ANTIGENS PROTEIN SPAS | | Authors: | Deane, J.E, Graham, S.C, Mitchell, E.P, Flot, D, Johnson, S, Lea, S.M. | | Deposit date: | 2008-05-08 | | Release date: | 2008-05-20 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structure of Spa40, the Specificity Switch for the Shigella Flexneri Type III Secretion System
Mol.Microbiol., 69, 2008
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2WFO
 | | Crystal structure of Machupo virus envelope glycoprotein GP1 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCOPROTEIN 1 | | Authors: | Bowden, T.A, Crispin, M, Graham, S.C, Harvey, D.J, Grimes, J.M, Jones, E.Y, Stuart, D.I. | | Deposit date: | 2009-04-09 | | Release date: | 2009-06-16 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (1.73 Å) | | Cite: | Unusual Molecular Architecture of the Machupo Virus Attachment Glycoprotein.
J.Virol., 83, 2009
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2VSC
 | | Structure of the immunoglobulin-superfamily ectodomain of human CD47 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, LEUKOCYTE SURFACE ANTIGEN CD47, MAGNESIUM ION | | Authors: | Hatherley, D, Graham, S.C, Turner, J, Harlos, K, Stuart, D.I, Barclay, A.N. | | Deposit date: | 2008-04-22 | | Release date: | 2008-08-12 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Paired Receptor Specificity Explained by Structures of Signal Regulatory Proteins Alone and Complexed with Cd47.
Mol.Cell, 31, 2008
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2X46
 | | Crystal Structure of SeMet Arg r 1 | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ALLERGEN ARG R 1 | | Authors: | Paesen, G.C, Siebold, C, Syme, N, Harlos, K, Graham, S.C, Hilger, C, Homans, S.W, Hentges, F, Stuart, D.I. | | Deposit date: | 2010-01-28 | | Release date: | 2011-02-09 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1 Å) | | Cite: | Crystal Structure of the Allergen Arg R 1, a Histamine-Binding Lipocalin from a Soft Tick
To be Published
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2WNG
 | | complete extracellular structure of human signal regulatory protein (SIRP) alpha | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1 | | Authors: | Hatherley, D, Graham, S.C, Harlos, K, Stuart, D.I, Barclay, A.N. | | Deposit date: | 2009-07-09 | | Release date: | 2009-07-21 | | Last modified: | 2023-12-13 | | Method: | X-RAY DIFFRACTION (2.49 Å) | | Cite: | Structure of Signal-Regulatory Protein Alpha: A Link to Antigen Receptor Evolution.
J.Biol.Chem., 284, 2009
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6I2M
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