3V16
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![BU of 3v16 by Molmil](/molmil-images/mine/3v16) | An intramolecular pi-cation latch in phosphatidylinositol-specific phospholipase C from S.aureus controls substrate access to the active site | Descriptor: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, 1-phosphatidylinositol phosphodiesterase, CHLORIDE ION | Authors: | Goldstein, R.I, Cheng, J, Stec, B, Roberts, M.F. | Deposit date: | 2011-12-09 | Release date: | 2012-04-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structure of the S. aureus PI-Specific Phospholipase C Reveals Modulation of Active Site Access by a Titratable PI-Cation Latched Loop Biochemistry, 51, 2012
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3V18
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![BU of 3v18 by Molmil](/molmil-images/mine/3v18) | Structure of the Phosphatidylinositol-specific phospholipase C from Staphylococcus aureus | Descriptor: | 1-phosphatidylinositol phosphodiesterase, ISOPROPYL ALCOHOL, SULFATE ION | Authors: | Goldstein, R.I, Cheng, J, Stec, B, Roberts, M.F. | Deposit date: | 2011-12-09 | Release date: | 2012-04-04 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Structure of the S. aureus PI-Specific Phospholipase C Reveals Modulation of Active Site Access by a Titratable PI-Cation Latched Loop Biochemistry, 51, 2012
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3V1H
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![BU of 3v1h by Molmil](/molmil-images/mine/3v1h) | Structure of the H258Y mutant of Phosphatidylinositol-specific phospholipase C from Staphylococcus aureus | Descriptor: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, 1-phosphatidylinositol phosphodiesterase, ACETATE ION | Authors: | Goldstein, R.I, Cheng, J, Stec, B, Roberts, M.F. | Deposit date: | 2011-12-09 | Release date: | 2012-04-04 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of the S. aureus PI-Specific Phospholipase C Reveals Modulation of Active Site Access by a Titratable PI-Cation Latched Loop Biochemistry, 51, 2012
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6B62
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![BU of 6b62 by Molmil](/molmil-images/mine/6b62) | IMPase (AF2372) with 400 mM Glutamate | Descriptor: | Fructose-1,6-bisphosphatase/inositol-1-monophosphatase, GLUTAMIC ACID, GLYCEROL, ... | Authors: | Goldstein, R.I, Roberts, M. | Deposit date: | 2017-10-01 | Release date: | 2018-10-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.003 Å) | Cite: | Osmolyte binding capacity of a dual action IMPase/FBPase (AF2372) To Be Published
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6B63
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![BU of 6b63 by Molmil](/molmil-images/mine/6b63) | IMPase (AF2372) with 25 mM Asp | Descriptor: | (2R)-2,3-dihydroxypropyl (2S)-2,3-dihydroxypropyl hydrogen phosphate, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Fructose-1,6-bisphosphatase/inositol-1-monophosphatase, ... | Authors: | Goldstein, R.I, Roberts, M. | Deposit date: | 2017-10-01 | Release date: | 2018-10-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.696 Å) | Cite: | Osmolyte binding capacity of a dual action IMPase/FBPase (AF2372) To Be Published
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6B64
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![BU of 6b64 by Molmil](/molmil-images/mine/6b64) | IMPase (AF2372) with 25 mM Asp | Descriptor: | ASPARTIC ACID, Fructose-1,6-bisphosphatase/inositol-1-monophosphatase, MAGNESIUM ION, ... | Authors: | Goldstein, R.I, Roberts, M. | Deposit date: | 2017-10-01 | Release date: | 2018-10-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Osmolyte binding capacity of a dual action IMPase/FBPase (AF2372) To Be Published
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6B65
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![BU of 6b65 by Molmil](/molmil-images/mine/6b65) | IMPase (AF2372) R92Q/K164E | Descriptor: | DI(HYDROXYETHYL)ETHER, Fructose-1,6-bisphosphatase/inositol-1-monophosphatase, ISOPROPYL ALCOHOL, ... | Authors: | Goldstein, R.I, Roberts, M. | Deposit date: | 2017-10-01 | Release date: | 2018-10-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.702 Å) | Cite: | Osmolyte binding capacity of a dual action IMPase/FBPase (AF2372) To Be Published
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6B66
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![BU of 6b66 by Molmil](/molmil-images/mine/6b66) | IMPase (AF2372) R92Q/K164E with 400 mM Glutamate | Descriptor: | Fructose-1,6-bisphosphatase/inositol-1-monophosphatase, GLUTAMIC ACID, GLYCEROL, ... | Authors: | Goldstein, R.I, Roberts, M. | Deposit date: | 2017-10-01 | Release date: | 2018-10-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Osmolyte binding capacity of a dual action IMPase/FBPase (AF2372) To Be Published
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6B5Z
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![BU of 6b5z by Molmil](/molmil-images/mine/6b5z) | IMPase (AF2372) with 25 mM Asp | Descriptor: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, ASPARTIC ACID, Fructose-1,6-bisphosphatase/inositol-1-monophosphatase, ... | Authors: | Goldstein, R.I, Roberts, M. | Deposit date: | 2017-10-01 | Release date: | 2018-10-03 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Osmolyte binding capacity of a dual action IMPase/FBPase (AF2372) To Be Published
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6B61
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![BU of 6b61 by Molmil](/molmil-images/mine/6b61) | IMPase (AF2372) with 25 mM Asp | Descriptor: | ASPARTIC ACID, Fructose-1,6-bisphosphatase/inositol-1-monophosphatase, MAGNESIUM ION, ... | Authors: | Goldstein, R.I, Roberts, M. | Deposit date: | 2017-10-01 | Release date: | 2018-10-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Osmolyte binding capacity of a dual action IMPase/FBPase (AF2372) To Be Published
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6B60
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![BU of 6b60 by Molmil](/molmil-images/mine/6b60) | IMPase (AF2372) with 25 mM Glutamate | Descriptor: | DI(HYDROXYETHYL)ETHER, Fructose-1,6-bisphosphatase/inositol-1-monophosphatase, GLUTAMIC ACID, ... | Authors: | Goldstein, R.I, Roberts, M.F. | Deposit date: | 2017-10-01 | Release date: | 2018-10-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Osmolyte binding capacity of a dual action IMPase/FBPase (AF2372) To Be Published
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4I8Y
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![BU of 4i8y by Molmil](/molmil-images/mine/4i8y) | Structure of the unliganded N254Y/H258Y mutant of the phosphatidylinositol-specific phospholipase C from S. aureus | Descriptor: | 1-phosphatidylinositol phosphodiesterase, ACETATE ION, CHLORIDE ION | Authors: | Goldstein, R.I, Cheng, J, Stec, B, Gershenson, A, Roberts, M.F. | Deposit date: | 2012-12-04 | Release date: | 2013-04-10 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The cation-pi box is a specific phosphatidylcholine membrane targeting motif. J.Biol.Chem., 288, 2013
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4I9J
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![BU of 4i9j by Molmil](/molmil-images/mine/4i9j) | Structure of the N254Y/H258Y mutant of the phosphatidylinositol-specific phospholipase C from S. aureus bound to diC4PC | Descriptor: | (4S,7R)-7-(heptanoyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-3,5,9-trioxa-4-phosphahexadecan-1-aminium 4-oxide, 1-phosphatidylinositol phosphodiesterase, ACETATE ION | Authors: | Goldstein, R.I, Cheng, J, Stec, B, Gershenson, A, Roberts, M.F. | Deposit date: | 2012-12-05 | Release date: | 2013-04-10 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The cation-pi box is a specific phosphatidylcholine membrane targeting motif. J.Biol.Chem., 288, 2013
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4I90
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![BU of 4i90 by Molmil](/molmil-images/mine/4i90) | Structure of the N254Y/H258Y mutant of the phosphatidylinositol-specific phospholipase C from S. aureus bound to choline | Descriptor: | 1-phosphatidylinositol phosphodiesterase, ACETATE ION, CHLORIDE ION, ... | Authors: | Goldstein, R.I, Cheng, J, Stec, B, Gershenson, A, Roberts, M.F. | Deposit date: | 2012-12-04 | Release date: | 2013-04-10 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | The cation-pi box is a specific phosphatidylcholine membrane targeting motif. J.Biol.Chem., 288, 2013
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4I9M
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![BU of 4i9m by Molmil](/molmil-images/mine/4i9m) | Structure of the N254Y/H258Y mutant of the phosphatidylinositol-specific phospholipase C from Staphylococcus aureus bound to HEPES | Descriptor: | 1-phosphatidylinositol phosphodiesterase, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SULFATE ION | Authors: | Goldstein, R.I, Cheng, J, Stec, B, Gershenson, A, Roberts, M.F. | Deposit date: | 2012-12-05 | Release date: | 2013-04-10 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The cation-pi box is a specific phosphatidylcholine membrane targeting motif. J.Biol.Chem., 288, 2013
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4I9T
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![BU of 4i9t by Molmil](/molmil-images/mine/4i9t) | Structure of the H258Y mutant of the phosphatidylinositol-specific phospholipase C from Staphylococcus aureus | Descriptor: | 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, 1-phosphatidylinositol phosphodiesterase, SULFATE ION, ... | Authors: | Goldstein, R.I, Cheng, J, Stec, B, Gershenson, A, Roberts, M.F. | Deposit date: | 2012-12-05 | Release date: | 2013-04-10 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The cation-pi box is a specific phosphatidylcholine membrane targeting motif. J.Biol.Chem., 288, 2013
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