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PDB: 71 件
4DUI
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BU of 4dui by Molmil
DARPIN D1 binding to tubulin beta chain (not in complex)
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN) D1
著者Pecqueur, L, Duellberg, C, Dreier, B, Wang, Q, Jiang, C, Pluckthun, A, Surrey, T, Gigant, B, Knossow, M.
登録日2012-02-22
公開日2013-02-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.16 Å)
主引用文献An Anti-Tubulin Darpin Caps the Microtubule Plus-End
To be Published
1EO8
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BU of 1eo8 by Molmil
INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY (HEAVY CHAIN), ...
著者Fleury, D, Gigant, B, Daniels, R.S, Skehel, J.J, Knossow, M, Bizebard, T.
登録日2000-03-22
公開日2000-04-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural evidence for recognition of a single epitope by two distinct antibodies.
Proteins, 40, 2000
5MIO
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BU of 5mio by Molmil
KIF2C-DARPIN FUSION PROTEIN BOUND TO TUBULIN
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF2C,KIF2C FUSED TO A DARPIN,KIF2C FUSED TO A DARPIN, ...
著者Wang, W, Gigant, B.
登録日2016-11-28
公開日2017-07-19
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Insight into microtubule disassembly by kinesin-13s from the structure of Kif2C bound to tubulin.
Nat Commun, 8, 2017
5LT3
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BU of 5lt3 by Molmil
nucleotide-free kinesin-1 motor domain T87A mutant, P1 crystal form
分子名称: Kinesin-1 heavy chain, SULFATE ION
著者Cao, L, Gigant, B.
登録日2016-09-06
公開日2017-03-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献The structural switch of nucleotide-free kinesin.
Sci Rep, 7, 2017
5LT4
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BU of 5lt4 by Molmil
nucleotide-free kinesin-1 motor domain T92V mutant, P1 crystal form
分子名称: Kinesin-1 heavy chain, SULFATE ION
著者Cao, L, Gigant, B.
登録日2016-09-06
公開日2017-03-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.881 Å)
主引用文献The structural switch of nucleotide-free kinesin.
Sci Rep, 7, 2017
5LT1
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BU of 5lt1 by Molmil
nucleotide-free kinesin-1 motor domain T92V mutant, P21 crystal form
分子名称: ACETATE ION, Kinesin-like protein, STRONTIUM ION, ...
著者Cao, L, Gigant, B.
登録日2016-09-06
公開日2017-03-01
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.949 Å)
主引用文献The structural switch of nucleotide-free kinesin.
Sci Rep, 7, 2017
3HKB
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BU of 3hkb by Molmil
Tubulin: RB3 Stathmin-like domain complex
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Dorleans, A, Gigant, B, Ravelli, R.B.G, Mailliet, P, Mikol, V, Knossow, M.
登録日2009-05-23
公開日2009-09-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.65 Å)
主引用文献Variations in the colchicine-binding domain provide insight into the structural switch of tubulin
Proc.Natl.Acad.Sci.USA, 106, 2009
3HKC
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BU of 3hkc by Molmil
Tubulin-ABT751: RB3 stathmin-like domain complex
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Dorleans, A, Gigant, B, Ravelli, R.B.G, Mailliet, P, Mikol, V, Knossow, M.
登録日2009-05-23
公開日2009-09-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Variations in the colchicine-binding domain provide insight into the structural switch of tubulin
Proc.Natl.Acad.Sci.USA, 106, 2009
3HKE
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BU of 3hke by Molmil
Tubulin-T138067: RB3 stathmin-like domain complex
分子名称: 2,3,4,5,6-pentafluoro-N-(3-fluoro-4-methoxyphenyl)benzenesulfonamide, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Dorleans, A, Gigant, B, Ravelli, R.B.G, Mailliet, P, Mikol, V, Knossow, M.
登録日2009-05-23
公開日2009-09-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Variations in the colchicine-binding domain provide insight into the structural switch of tubulin
Proc.Natl.Acad.Sci.USA, 106, 2009
3HKD
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BU of 3hkd by Molmil
Tubulin-TN16 : RB3 stathmin-like domain complex
分子名称: (3Z,5S)-5-benzyl-3-[1-(phenylamino)ethylidene]pyrrolidine-2,4-dione, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Dorleans, A, Gigant, B, Ravelli, R.B.G, Mailliet, P, Mikol, V, Knossow, M.
登録日2009-05-23
公開日2009-09-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Variations in the colchicine-binding domain provide insight into the structural switch of tubulin
Proc.Natl.Acad.Sci.USA, 106, 2009
3RYI
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BU of 3ryi by Molmil
GDP-Tubulin: rb3 stathmin-like domain complex
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Nawrotek, A, Knossow, M, Gigant, B.
登録日2011-05-11
公開日2011-10-05
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Determinants That Govern Microtubule Assembly from the Atomic Structure of GTP-Tubulin.
J.Mol.Biol., 412, 2011
3RYC
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BU of 3ryc by Molmil
Tubulin: RB3 stathmin-like domain complex
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Nawrotek, A, Knossow, M, Gigant, B.
登録日2011-05-11
公開日2011-10-05
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Determinants That Govern Microtubule Assembly from the Atomic Structure of GTP-Tubulin.
J.Mol.Biol., 412, 2011
3RYH
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BU of 3ryh by Molmil
GMPCPP-Tubulin: RB3 Stathmin-like domain complex
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, ...
著者Nawrotek, A, Knossow, M, Gigant, B.
登録日2011-05-11
公開日2011-10-05
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Determinants That Govern Microtubule Assembly from the Atomic Structure of GTP-Tubulin.
J.Mol.Biol., 412, 2011
3RYF
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BU of 3ryf by Molmil
GTP-Tubulin: RB3 Stathmin-like domain complex
分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, SULFATE ION, ...
著者Nawrotek, A, Knossow, M, Gigant, B.
登録日2011-05-11
公開日2011-10-05
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献The Determinants That Govern Microtubule Assembly from the Atomic Structure of GTP-Tubulin.
J.Mol.Biol., 412, 2011
6TDE
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BU of 6tde by Molmil
Tubulin-inhibitor complex
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Varela, P.F, Gigant, B.
登録日2019-11-08
公開日2020-09-02
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.286 Å)
主引用文献Discovery of dihydrofuranoallocolchicinoids - Highly potent antimitotic agents with low acute toxicity.
Eur.J.Med.Chem., 207, 2020
2VIU
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BU of 2viu by Molmil
INFLUENZA VIRUS HEMAGGLUTININ
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Bizebard, T, Fleury, D, Gigant, B, Wharton, S.A, Skehel, J.J, Knossow, M.
登録日1997-12-22
公開日1998-04-29
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Antigen distortion allows influenza virus to escape neutralization.
Nat.Struct.Biol., 5, 1998
2VIR
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BU of 2vir by Molmil
INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY
分子名称: HEMAGGLUTININ, IMMUNOGLOBULIN (IGG1, LAMBDA), ...
著者Bizebard, T, Fleury, D, Gigant, B, Wharton, S.A, Skehel, J.J, Knossow, M.
登録日1997-12-22
公開日1998-04-29
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Antigen distortion allows influenza virus to escape neutralization.
Nat.Struct.Biol., 5, 1998
2VIS
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BU of 2vis by Molmil
INFLUENZA VIRUS HEMAGGLUTININ, (ESCAPE) MUTANT WITH THR 131 REPLACED BY ILE, COMPLEXED WITH A NEUTRALIZING ANTIBODY
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, HEMAGGLUTININ, IMMUNOGLOBULIN (IGG1, ...
著者Bizebard, T, Fleury, D, Gigant, B, Wharton, S.A, Skehel, J.J, Knossow, M.
登録日1997-12-22
公開日1998-04-29
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Antigen distortion allows influenza virus to escape neutralization.
Nat.Struct.Biol., 5, 1998
2VIT
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BU of 2vit by Molmil
INFLUENZA VIRUS HEMAGGLUTININ, MUTANT WITH THR 155 REPLACED BY ILE, COMPLEXED WITH A NEUTRALIZING ANTIBODY
分子名称: HEMAGGLUTININ, IMMUNOGLOBULIN (IGG1, LAMBDA), ...
著者Bizebard, T, Fleury, D, Gigant, B, Wharton, S.A, Skehel, J.J, Knossow, M.
登録日1997-12-22
公開日1998-04-29
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Antigen distortion allows influenza virus to escape neutralization.
Nat.Struct.Biol., 5, 1998
6H9B
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BU of 6h9b by Molmil
1,1-Diheterocyclic Ethylenes Derived from Quinaldine and Carbazole as New Tubulin Polymerization Inhibitors: Synthesis, Metabolism, and Biological Evaluation
分子名称: 9-methyl-3-[1-(2-methylquinolin-4-yl)ethenyl]carbazole, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Varela, P.F, Gigant, B.
登録日2018-08-03
公開日2018-12-19
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献1,1-Diheterocyclic Ethylenes Derived from Quinaldine and Carbazole as New Tubulin-Polymerization Inhibitors: Synthesis, Metabolism, and Biological Evaluation.
J. Med. Chem., 62, 2019
4EB6
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BU of 4eb6 by Molmil
Tubulin-Vinblastine: Stathmin-like complex
分子名称: (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Ranaivoson, F.M, Gigant, B, Knossow, M.
登録日2012-03-23
公開日2012-08-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.47 Å)
主引用文献Structural plasticity of tubulin assembly probed by vinca-domain ligands.
Acta Crystallogr.,Sect.D, 68, 2012
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