1EO8
| INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY (HEAVY CHAIN), ... | 著者 | Fleury, D, Gigant, B, Daniels, R.S, Skehel, J.J, Knossow, M, Bizebard, T. | 登録日 | 2000-03-22 | 公開日 | 2000-04-12 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural evidence for recognition of a single epitope by two distinct antibodies. Proteins, 40, 2000
|
|
7Q1F
| CPAP:TUBULIN:IE5 ALPHAREP COMPLEX | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CITRATE ANION, Centromere protein J, ... | 著者 | Campanacci, V, Gigant, b. | 登録日 | 2021-10-19 | 公開日 | 2022-04-20 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.347 Å) | 主引用文献 | Structural convergence for tubulin binding of CPAP and vinca domain microtubule inhibitors. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7Q1E
| CPAP:TUBULIN:IIH5 ALPHAREP COMPLEX | 分子名称: | Centromere protein J, GLYCEROL, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Campanacci, V, Gigant, b. | 登録日 | 2021-10-19 | 公開日 | 2022-04-13 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural convergence for tubulin binding of CPAP and vinca domain microtubule inhibitors. Proc.Natl.Acad.Sci.USA, 119, 2022
|
|
7A5E
| OSM-3 kinesin motor domain complexed with Mg.AMPPNP | 分子名称: | GLYCEROL, MAGNESIUM ION, Osmotic avoidance abnormal protein 3, ... | 著者 | Varela, F.P, Menetrey, J, Gigant, B. | 登録日 | 2020-08-21 | 公開日 | 2021-02-03 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.904 Å) | 主引用文献 | Structural snapshots of the kinesin-2 OSM-3 along its nucleotide cycle: implications for the ATP hydrolysis mechanism. Febs Open Bio, 11, 2021
|
|
4Y05
| KIF2C short Loop2 construct | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF2C, MAGNESIUM ION, ... | 著者 | Wang, W, Knossow, M, Gigant, B. | 登録日 | 2015-02-05 | 公開日 | 2015-06-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | New Insights into the Coupling between Microtubule Depolymerization and ATP Hydrolysis by Kinesin-13 Protein Kif2C. J.Biol.Chem., 290, 2015
|
|
1KEN
| INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH AN ANTIBODY THAT PREVENTS THE HEMAGGLUTININ LOW PH FUSOGENIC TRANSITION | 分子名称: | alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin HA1, hemagglutinin HA2, ... | 著者 | Barbey-Martin, C, Gigant, B, Bizebard, T, Calder, L.J, Wharto, S.A, Skehel, J.J, Knossow, M. | 登録日 | 2001-11-16 | 公開日 | 2002-04-24 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | An Antibody that Prevents the Hemagglutinin Low pH Fusogenic Transition VIROLOGY, 294, 2002
|
|
4LNU
| Nucleotide-free kinesin motor domain in complex with tubulin and a DARPin | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Designed ankyrin repeat protein (DARPIN) D1, GLYCEROL, ... | 著者 | Cao, L, Gigant, B, Knossow, M. | 登録日 | 2013-07-12 | 公開日 | 2014-12-03 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | 主引用文献 | The structure of apo-kinesin bound to tubulin links the nucleotide cycle to movement Nat Commun, 5, 2014
|
|
7A40
| |
1KNO
| |
4P3Z
| Chlamydia pneumoniae CopN (D29 construct) | 分子名称: | CopN, GLYCEROL, SULFATE ION | 著者 | Nawrotek, A, Guimaraes, B.G, Knossow, M, Gigant, B. | 登録日 | 2014-03-10 | 公開日 | 2014-07-30 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Biochemical and Structural Insights into Microtubule Perturbation by CopN from Chlamydia pneumoniae. J.Biol.Chem., 289, 2014
|
|
4P40
| Chlamydia pneumoniae CopN | 分子名称: | CHLORIDE ION, CopN, DIMETHYLAMINE, ... | 著者 | Nawrotek, A, Guimaraes, B.G, Knossow, M, Gigant, B. | 登録日 | 2014-03-10 | 公開日 | 2014-07-30 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Biochemical and Structural Insights into Microtubule Perturbation by CopN from Chlamydia pneumoniae. J.Biol.Chem., 289, 2014
|
|
7A3Z
| |
3UT5
| Tubulin-Colchicine-Ustiloxin: Stathmin-like domain complex | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Ranaivoson, F.M, Gigant, B, Knossow, M. | 登録日 | 2011-11-25 | 公開日 | 2012-08-01 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | Structural plasticity of tubulin assembly probed by vinca-domain ligands. Acta Crystallogr.,Sect.D, 68, 2012
|
|
1QFU
| INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (HEMAGGLUTININ (HA1 CHAIN)), ... | 著者 | Fleury, D, Gigant, B, Bizebard, T, Daniels, R.S, Skehel, J.J, Knossow, M. | 登録日 | 1999-04-14 | 公開日 | 1999-04-16 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A complex of influenza hemagglutinin with a neutralizing antibody that binds outside the virus receptor binding site. Nat.Struct.Biol., 6, 1999
|
|
1SA1
| Tubulin-podophyllotoxin: stathmin-like domain complex | 分子名称: | 9-HYDROXY-5-(3,4,5-TRIMETHOXYPHENYL)-5,8,8A,9-TETRAHYDROFURO[3',4':6,7]NAPHTHO[2,3-D][1,3]DIOXOL-6(5AH)-ONE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Ravelli, R.B, Gigant, B, Curmi, P.A, Jourdain, I, Lachkar, S, Sobel, A, Knossow, M. | 登録日 | 2004-02-06 | 公開日 | 2004-03-23 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (4.2 Å) | 主引用文献 | Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain. Nature, 428, 2004
|
|
1SA0
| TUBULIN-COLCHICINE: STATHMIN-LIKE DOMAIN COMPLEX | 分子名称: | 2-MERCAPTO-N-[1,2,3,10-TETRAMETHOXY-9-OXO-5,6,7,9-TETRAHYDRO-BENZO[A]HEPTALEN-7-YL]ACETAMIDE, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Ravelli, R.B, Gigant, B, Curmi, P.A, Jourdain, I, Lachkar, S, Sobel, A, Knossow, M. | 登録日 | 2004-02-06 | 公開日 | 2004-03-23 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.58 Å) | 主引用文献 | Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain. Nature, 428, 2004
|
|
6H9B
| 1,1-Diheterocyclic Ethylenes Derived from Quinaldine and Carbazole as New Tubulin Polymerization Inhibitors: Synthesis, Metabolism, and Biological Evaluation | 分子名称: | 9-methyl-3-[1-(2-methylquinolin-4-yl)ethenyl]carbazole, GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | 著者 | Varela, P.F, Gigant, B. | 登録日 | 2018-08-03 | 公開日 | 2018-12-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | 1,1-Diheterocyclic Ethylenes Derived from Quinaldine and Carbazole as New Tubulin-Polymerization Inhibitors: Synthesis, Metabolism, and Biological Evaluation. J. Med. Chem., 62, 2019
|
|
5LT1
| |
5EYL
| TUBULIN-BINDING DARPIN | 分子名称: | DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN), GLYCEROL, PHOSPHATE ION | 著者 | Ahmad, S, Kossow, M, Gigant, B. | 登録日 | 2015-11-25 | 公開日 | 2016-07-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | Destabilizing an interacting motif strengthens the association of a designed ankyrin repeat protein with tubulin. Sci Rep, 6, 2016
|
|
5EYP
| TUBULIN-DARPIN COMPLEX | 分子名称: | DESIGNED ANKYRIN REPEAT PROTEIN (DARPIN), GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Ahmad, S, Knossow, M, Gigant, B. | 登録日 | 2015-11-25 | 公開日 | 2016-07-20 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Destabilizing an interacting motif strengthens the association of a designed ankyrin repeat protein with tubulin. Sci Rep, 6, 2016
|
|
5MIO
| KIF2C-DARPIN FUSION PROTEIN BOUND TO TUBULIN | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Kinesin-like protein KIF2C,KIF2C FUSED TO A DARPIN,KIF2C FUSED TO A DARPIN, ... | 著者 | Wang, W, Gigant, B. | 登録日 | 2016-11-28 | 公開日 | 2017-07-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | 主引用文献 | Insight into microtubule disassembly by kinesin-13s from the structure of Kif2C bound to tubulin. Nat Commun, 8, 2017
|
|
5LT2
| |
5LT4
| |
5LT3
| |
4DRX
| GTP-Tubulin in complex with a DARPIN | 分子名称: | Designed ankyrin repeat protein (DARPIN) D1, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Pecqueur, L, Gigant, B, Knossow, M. | 登録日 | 2012-02-17 | 公開日 | 2012-07-11 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.22 Å) | 主引用文献 | A designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus end. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|