7R59
 
 | | PARP2 catalytic domain in complex with OUL245 | | 分子名称: | GLYCEROL, Poly [ADP-ribose] polymerase 2, [1,2,4]triazolo[3,4-b][1,3]benzothiazol-6-ol | | 著者 | Galera-Prat, A, Maksimainen, M.M, Lehtio, L. | | 登録日 | 2022-02-10 | | 公開日 | 2023-01-25 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | [1,2,4]Triazolo[3,4- b ]benzothiazole Scaffold as Versatile Nicotinamide Mimic Allowing Nanomolar Inhibition of Different PARP Enzymes.
J.Med.Chem., 66, 2023
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7AEO
 | | Human ARTD2 in complex with DNA oligonucleotides | | 分子名称: | DNA, Poly [ADP-ribose] polymerase 2, SULFATE ION | | 著者 | Obaji, E, Maksimainen, M.M, Galera-Prat, A, Lehtio, L. | | 登録日 | 2020-09-17 | | 公開日 | 2021-05-19 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Activation of PARP2/ARTD2 by DNA damage induces conformational changes relieving enzyme autoinhibition.
Nat Commun, 12, 2021
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