8UU4
| Cryo-EM structure of the Listeria innocua 70S ribosome in complex with HPF (structure I-A) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 5S Ribosomal RNA, ... | 著者 | Seely, S.M, Basu, R.S, Gagnon, M.G. | 登録日 | 2023-10-31 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Mechanistic insights into the alternative ribosome recycling by HflXr. Nucleic Acids Res., 52, 2024
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8UU5
| Cryo-EM structure of the Listeria innocua 70S ribosome (head-swiveled) in complex with pe/E-tRNA (structure I-B) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 5S Ribosomal RNA, ... | 著者 | Seely, S.M, Basu, R.S, Gagnon, M.G. | 登録日 | 2023-10-31 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Mechanistic insights into the alternative ribosome recycling by HflXr. Nucleic Acids Res., 52, 2024
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8UU8
| Cryo-EM structure of the Listeria innocua 70S ribosome (head-swiveled) in complex with HflXr and pe/E-tRNA (structure II-C) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 5S Ribosomal RNA, ... | 著者 | Seely, S.M, Basu, R.S, Gagnon, M.G. | 登録日 | 2023-10-31 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Mechanistic insights into the alternative ribosome recycling by HflXr. Nucleic Acids Res., 52, 2024
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8UU9
| Cryo-EM structure of the ratcheted Listeria innocua 70S ribosome (head-swiveled) in complex with HflXr and pe/E-tRNA (structure II-D) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 5S Ribosomal RNA, ... | 著者 | Seely, S.M, Basu, R.S, Gagnon, M.G. | 登録日 | 2023-10-31 | 公開日 | 2024-02-28 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Mechanistic insights into the alternative ribosome recycling by HflXr. Nucleic Acids Res., 52, 2024
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8FZF
| Cryo-EM structure of an E. coli rotated ribosome complex bound with RF3-ppGpp and p/E-tRNAPhe (Composite state I-C) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | 登録日 | 2023-01-28 | 公開日 | 2024-06-26 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | The ribosome termination complex remodels release factor RF3 and ejects GDP. Nat.Struct.Mol.Biol., 2024
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8FZE
| Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with RF1, P- and E-site tRNAPhe (State I-A) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | 登録日 | 2023-01-28 | 公開日 | 2024-07-17 | 最終更新日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | The ribosome termination complex remodels release factor RF3 and ejects GDP. Nat.Struct.Mol.Biol., 2024
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8FZI
| Cryo-EM structure of an E. coli rotated ribosome bound with RF3-GDPCP and p/E-tRNAPhe (Composite state II-B) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | 登録日 | 2023-01-28 | 公開日 | 2024-07-17 | 最終更新日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The ribosome termination complex remodels release factor RF3 and ejects GDP. Nat.Struct.Mol.Biol., 2024
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8FZD
| Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with apoRF3, RF1, P- and E-site tRNAPhe (Composite state I-B) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | 登録日 | 2023-01-28 | 公開日 | 2024-07-17 | 最終更新日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The ribosome termination complex remodels release factor RF3 and ejects GDP. Nat.Struct.Mol.Biol., 2024
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8FZJ
| Cryo-EM structure of an E. coli rotated ribosome bound with RF3-GDPCP and p/E-tRNAPhe (Composite state II-C) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | 登録日 | 2023-01-28 | 公開日 | 2024-07-17 | 最終更新日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | The ribosome termination complex remodels release factor RF3 and ejects GDP. Nat.Struct.Mol.Biol., 2024
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8FZG
| Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with RF3-GDPCP, RF1, P- and E-site tRNAPhe (Composite state II-A) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | 登録日 | 2023-01-28 | 公開日 | 2024-07-17 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The ribosome termination complex remodels release factor RF3 and ejects GDP. Nat.Struct.Mol.Biol., 2024
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8FZH
| Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with RF1, P- and E-site tRNAPhe (State II-D) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | 登録日 | 2023-01-28 | 公開日 | 2024-07-17 | 最終更新日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | The ribosome termination complex remodels release factor RF3 and ejects GDP. Nat.Struct.Mol.Biol., 2024
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4WQU
| Crystal structure of the Thermus thermophilus 70S ribosome in complex with elongation factor G trapped by the antibiotic dityromycin | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Lin, J, Gagnon, M.G, Steitz, T.A. | 登録日 | 2014-10-22 | 公開日 | 2015-01-28 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation. Cell, 160, 2015
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8V9J
| Cryo-EM structure of the Mycobacterium smegmatis 70S ribosome in complex with hibernation factor Msmeg1130 (Balon) (Structure 4) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S14, ... | 著者 | Rybak, M.Y, Helena-Bueno, K, Hill, C.H, Melnikov, S.V, Gagnon, M.G. | 登録日 | 2023-12-08 | 公開日 | 2024-02-07 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | A new family of bacterial ribosome hibernation factors. Nature, 626, 2024
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8V9K
| Cryo-EM structure of the Mycobacterium smegmatis 70S ribosome in complex with hibernation factor Rv2629 (Balon) (Structure 5) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S2, ... | 著者 | Rybak, M.Y, Helena-Bueno, K, Hill, C.H, Melnikov, S.V, Gagnon, M.G. | 登録日 | 2023-12-08 | 公開日 | 2024-02-07 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | A new family of bacterial ribosome hibernation factors. Nature, 626, 2024
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8V9L
| Cryo-EM structure of the Mycobacterium smegmatis 70S ribosome in complex with hibernation factor Msmeg1130 (Balon) and MsmegEF-Tu(GDP) (Composite structure 6) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S2, ... | 著者 | Rybak, M.Y, Helena-Bueno, K, Hill, C.H, Melnikov, S.V, Gagnon, M.G. | 登録日 | 2023-12-08 | 公開日 | 2024-02-07 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | A new family of bacterial ribosome hibernation factors. Nature, 626, 2024
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4WPO
| Crystal structure of the Thermus thermophilus 70S ribosome in complex with elongation factor G in the pre-translocational state | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Lin, J, Gagnon, M.G, Steitz, T.A. | 登録日 | 2014-10-20 | 公開日 | 2015-01-28 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation. Cell, 160, 2015
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7UNW
| Pseudomonas aeruginosa 70S ribosome initiation complex bound to IF2-GDPCP (structure II-B) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Basu, R.S, Sherman, M.B, Gagnon, M.G. | 登録日 | 2022-04-11 | 公開日 | 2022-06-22 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Compact IF2 allows initiator tRNA accommodation into the P site and gates the ribosome to elongation Nat Commun, 13, 2022
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7UNV
| Pseudomonas aeruginosa 70S ribosome initiation complex bound to IF2-GDPCP (structure II-A) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Basu, R.S, Sherman, M.B, Gagnon, M.G. | 登録日 | 2022-04-11 | 公開日 | 2022-06-22 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Compact IF2 allows initiator tRNA accommodation into the P site and gates the ribosome to elongation Nat Commun, 13, 2022
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7UNU
| Pseudomonas aeruginosa 70S ribosome initiation complex bound to compact IF2-GDP (composite structure I-B) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Basu, R.S, Sherman, M.B, Gagnon, M.G. | 登録日 | 2022-04-11 | 公開日 | 2022-06-22 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Compact IF2 allows initiator tRNA accommodation into the P site and gates the ribosome to elongation Nat Commun, 13, 2022
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7UNR
| Pseudomonas aeruginosa 70S ribosome initiation complex bound to compact IF2-GDP (composite structure I-A) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Basu, R.S, Sherman, M.B, Gagnon, M.G. | 登録日 | 2022-04-11 | 公開日 | 2022-06-22 | 最終更新日 | 2024-02-14 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Compact IF2 allows initiator tRNA accommodation into the P site and gates the ribosome to elongation Nat Commun, 13, 2022
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7UIU
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7UNQ
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7UNT
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5FX6
| Novel inhibitors of human rhinovirus 3C protease | 分子名称: | RHINOVIRUS 3C PROTEASE, ethyl (4R)-4-[[(2S,4S)-1-[(2S)-3-methyl-2-[(5-methyl-1,2-oxazol-3-yl)carbonylamino]butanoyl]-4-phenyl-pyrrolidin-2-yl]carbonylamino]-5-[(3S)-2-oxidanylidenepyrrolidin-3-yl]pentanoate | 著者 | Kawatkar, S, Ek, M, Hoesch, V, Gagnon, M, Nilsson, E, Lister, T, Olsson, L, Patel, J, Yu, Q. | 登録日 | 2016-02-24 | 公開日 | 2016-06-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Design and Structure-Activity Relationships of Novel Inhibitors of Human Rhinovirus 3C Protease. Bioorg.Med.Chem.Lett., 26, 2016
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5FX5
| Novel inhibitors of human rhinovirus 3C protease | 分子名称: | GLYCEROL, RHINOVIRUS 3C PROTEASE, TETRAETHYLENE GLYCOL, ... | 著者 | Kawatkar, S, Ek, M, Hoesch, V, Gagnon, M, Nilsson, E, Lister, T, Olsson, L, Patel, J, Yu, Q. | 登録日 | 2016-02-24 | 公開日 | 2016-06-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Design and Structure-Activity Relationships of Novel Inhibitors of Human Rhinovirus 3C Protease. Bioorg.Med.Chem.Lett., 26, 2016
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