PDB Search results for query - Protein Data Bank Japan

PDB: 2 results

Crystal structure of human soluble adenylyl cyclase catalytic domain in complex with the inhibitor TDI-10228
Descriptor:	1,2-ETHANEDIOL, 4-chloranyl-6-[4-[(3-fluorophenyl)methyl]-1-methyl-pyrazol-3-yl]pyrimidin-2-amine, ACETATE ION, ...
Authors:	Steegborn, C, Fushimi, M.
Deposit date:	2023-02-28
Release date:	2023-04-26
Last modified:	2023-05-17
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Scaffold Hopping and Optimization of Small Molecule Soluble Adenyl Cyclase Inhibitors Led by Free Energy Perturbation. J.Chem.Inf.Model., 63, 2023

Complex of human soluble adenylyl cyclase 10 catalytic core with inhibitor TDI-10962
Descriptor:	1,2-ETHANEDIOL, 2-(dimethylamino)ethyl 5-(2-azanyl-6-chloranyl-pyrimidin-4-yl)-2-methyl-4-(phenylmethyl)pyrazole-3-carboxylate, ACETATE ION, ...
Authors:	Steegborn, C, Fushimi, M.
Deposit date:	2023-02-28
Release date:	2023-04-26
Last modified:	2023-05-17
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Scaffold Hopping and Optimization of Small Molecule Soluble Adenyl Cyclase Inhibitors Led by Free Energy Perturbation. J.Chem.Inf.Model., 63, 2023